LOCUS       NM_025534               4661 bp    mRNA    linear   ROD 04-MAR-2025
DEFINITION  Mus musculus coiled-coil domain containing 82 (Ccdc82), mRNA.
ACCESSION   NM_025534
VERSION     NM_025534.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4661)
  AUTHORS   Wang,N., Zhang,S., Langfelder,P., Ramanathan,L., Gao,F.,
            Plascencia,M., Vaca,R., Gu,X., Deng,L., Dionisio,L.E., Vu,H.,
            Maciejewski,E., Ernst,J., Prasad,B.C., Vogt,T.F., Horvath,S.,
            Aaronson,J.S., Rosinski,J. and Yang,X.W.
  TITLE     Distinct mismatch-repair complex genes set neuronal CAG-repeat
            expansion rate to drive selective pathogenesis in HD mice
  JOURNAL   Cell (2025) In press
   PUBMED   39938516
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 4661)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   3  (bases 1 to 4661)
  AUTHORS   Gerhard,D.S., Wagner,L., Feingold,E.A., Shenmen,C.M., Grouse,L.H.,
            Schuler,G., Klein,S.L., Old,S., Rasooly,R., Good,P., Guyer,M.,
            Peck,A.M., Derge,J.G., Lipman,D., Collins,F.S., Jang,W., Sherry,S.,
            Feolo,M., Misquitta,L., Lee,E., Rotmistrovsky,K., Greenhut,S.F.,
            Schaefer,C.F., Buetow,K., Bonner,T.I., Haussler,D., Kent,J.,
            Kiekhaus,M., Furey,T., Brent,M., Prange,C., Schreiber,K.,
            Shapiro,N., Bhat,N.K., Hopkins,R.F., Hsie,F., Driscoll,T.,
            Soares,M.B., Casavant,T.L., Scheetz,T.E., Brown-stein,M.J.,
            Usdin,T.B., Toshiyuki,S., Carninci,P., Piao,Y., Dudekula,D.B.,
            Ko,M.S., Kawakami,K., Suzuki,Y., Sugano,S., Gruber,C.E.,
            Smith,M.R., Simmons,B., Moore,T., Waterman,R., Johnson,S.L.,
            Ruan,Y., Wei,C.L., Mathavan,S., Gunaratne,P.H., Wu,J., Garcia,A.M.,
            Hulyk,S.W., Fuh,E., Yuan,Y., Sneed,A., Kowis,C., Hodgson,A.,
            Muzny,D.M., McPherson,J., Gibbs,R.A., Fahey,J., Helton,E.,
            Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M.,
            Madari,A., Young,A.C., Wetherby,K.D., Granite,S.J., Kwong,P.N.,
            Brinkley,C.P., Pearson,R.L., Bouffard,G.G., Blakesly,R.W.,
            Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J.,
            Myers,R.M., Butterfield,Y.S., Griffith,M., Griffith,O.L.,
            Krzywinski,M.I., Liao,N., Morin,R., Palmquist,D., Petrescu,A.S.,
            Skalska,U., Smailus,D.E., Stott,J.M., Schnerch,A., Schein,J.E.,
            Jones,S.J., Holt,R.A., Baross,A., Marra,M.A., Clifton,S.,
            Makowski,K.A., Bosak,S. and Malek,J.
  CONSRTM   MGC Project Team
  TITLE     The status, quality, and expansion of the NIH full-length cDNA
            project: the Mammalian Gene Collection (MGC)
  JOURNAL   Genome Res 14 (10B), 2121-2127 (2004)
   PUBMED   15489334
  REMARK    Erratum:[Genome Res. 2006 Jun;16(6):804. Morrin, Ryan [corrected to
            Morin, Ryan]]
REFERENCE   4  (bases 1 to 4661)
  AUTHORS   Zambrowicz,B.P., Abuin,A., Ramirez-Solis,R., Richter,L.J.,
            Piggott,J., BeltrandelRio,H., Buxton,E.C., Edwards,J., Finch,R.A.,
            Friddle,C.J., Gupta,A., Hansen,G., Hu,Y., Huang,W., Jaing,C.,
            Key,B.W. Jr., Kipp,P., Kohlhauff,B., Ma,Z.Q., Markesich,D.,
            Payne,R., Potter,D.G., Qian,N., Shaw,J., Schrick,J., Shi,Z.Z.,
            Sparks,M.J., Van Sligtenhorst,I., Vogel,P., Walke,W., Xu,N.,
            Zhu,Q., Person,C. and Sands,A.T.
  TITLE     Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap
            screen to identify potential targets for therapeutic intervention
  JOURNAL   Proc Natl Acad Sci U S A 100 (24), 14109-14114 (2003)
   PUBMED   14610273
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            MH423686.1 and MH423685.1.
            
            On Jul 30, 2020 this sequence version replaced NM_025534.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057326.1, SRR10662772.3099314.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN00849390
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-66                MH423686.1         150-215
            67-150              MH423686.1         2423-2506
            151-878             MH423686.1         5235-5962
            879-1083            MH423686.1         6390-6594
            1084-1176           MH423686.1         15900-15992
            1177-1301           MH423686.1         20351-20475
            1302-1472           MH423686.1         26189-26359
            1473-1658           MH423685.1         2660-2845
            1659-4661           MH423685.1         10476-13478
FEATURES             Location/Qualifiers
     source          1..4661
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9"
     gene            1..4661
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /note="coiled-coil domain containing 82"
                     /db_xref="GeneID:66396"
                     /db_xref="MGI:MGI:1913646"
     exon            1..66
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            67..150
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            151..878
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             165..1721
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 82"
                     /protein_id="NP_079810.2"
                     /db_xref="CCDS:CCDS57651.1"
                     /db_xref="GeneID:66396"
                     /db_xref="MGI:MGI:1913646"
                     /translation="MVHVRRHETRKNSKTQKPEQKSRVDWHRTKRSISQLFDSDEELD
                     SNEELDSDEEHDSGESIDSDEELDISKKSDINELPEKETELKLIKVESQGSNSKHLTN
                     TSNSSADEEQLKETKHNDLPDDEAHPGQAENHHNRHTGQILEEDMEDEYIKPGKRKRL
                     SSVMYDSDESDDSDILIRKASAKHPRRVVEDECSSLEMEQETPEKSSAARKREYHQKL
                     QELSERSRQRRRRNSGRNFEDSEKDSCSGTGEEDEDEDEDDYRYDEDGDDYMIDDFVV
                     RNEEGDDENSNQQGENLTTSQLKLVKQNSLYSFSDHYTHFERVVKALLINAFDESFLE
                     TLYAGTRKKSYAKDMLTSLHYLDNRFIQPRLESLVSRSRWKEQYKERVESYSNLNILS
                     KSPENCVCQACGLHRHCKFSVHLSGKLYNIRTMETDDFMSHDKQVFTVGRICVERTRI
                     YHKLKHFKFKLYQDCCLIAKPEEVGDEQVKDTVKRVFNHSKERGWIRKKYDQLQNFLN
                     SADYFQDEKF"
     exon            879..1083
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1084..1176
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1301
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1472
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..1658
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1659..4661
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4631..4636
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      4661
                     /gene="Ccdc82"
                     /gene_synonym="2310043N13Rik"
                     /note="major polyA site"
ORIGIN      
        1 aaggctggag tggagttggg tgaggcagga gcagaggcgg aggcggagac cgaggcgctt
       61 tgaaagcagt cattgtatag ccctggacag cgaatcagga gacctggttt ctaatccctg
      121 ctctgtcact aacaagcttt gtgatatttg aagcttaagt gaaaatggta catgttagaa
      181 gacacgaaac aagaaaaaat tctaaaaccc aaaaacctga acaaaaatct cgagttgatt
      241 ggcatcggac taaaagaagc atctcacagt tatttgatag tgatgaagag ctagatagta
      301 atgaggaact tgacagcgat gaagagcatg atagtgggga aagtattgac agtgatgaag
      361 agcttgatat tagcaagaag tctgatatta atgaactacc agaaaaggaa acagagctta
      421 aattaatcaa agttgaaagt cagggaagca acagtaaaca tcttacaaac accagcaata
      481 gttcagcaga tgaagaacaa ctgaaggaaa ccaaacataa tgacttacca gatgatgaag
      541 ctcaccctgg tcaagcagag aatcatcaca acagacacac tgggcaaatc ctagaggaag
      601 atatggaaga tgaatacatc aagccaggaa aaagaaaaag gctgtcctct gtgatgtatg
      661 acagtgatga gagcgatgac agtgatatcc taattagaaa agcaagtgct aaacacccac
      721 gcagggtggt cgaggatgaa tgttcttcat tggaaatgga gcaagaaact cctgagaagt
      781 catcagctgc tcgaaagcga gaataccacc agaagctaca ggagctttct gagagatcac
      841 gccagagacg gaggcgcaat agtggtagaa attttgagga ctctgaaaag gactcttgtt
      901 caggcactgg tgaggaggat gaagatgagg acgaggatga ttacagatat gatgaagatg
      961 gggatgatta catgattgat gattttgtag tgcgaaatga ggaaggcgat gacgagaata
     1021 gcaatcaaca aggagaaaat ctgactacat cacaactgaa attagtaaaa cagaattctc
     1081 tttattcttt tagtgaccat tatactcact ttgaaagagt tgtgaaggct cttctgatca
     1141 atgcttttga tgaatctttt ctggaaactt tgtatgctgg caccaggaag aaatcctacg
     1201 cgaaagatat gttgacatct cttcattatt tggataatcg ctttattcaa ccccgtctag
     1261 agagtttagt ctctagaagt cgatggaaag agcaatataa ggagcgggtt gaaagctact
     1321 ctaacttaaa catcctttca aagagccctg agaactgtgt atgccaggct tgtgggctgc
     1381 atcgccactg taaattttca gtgcatctct caggaaagtt atacaacatc aggacgatgg
     1441 aaacagatga tttcatgtca catgacaagc aggtgtttac tgttggcaga atttgtgttg
     1501 aacgtaccag aatttatcat aaactaaagc attttaaatt taaactgtac caagactgct
     1561 gcttaattgc aaaaccagaa gaagttggag atgaacaggt taaagataca gtaaagagag
     1621 tcttcaatca ttcaaaagaa agaggctgga ttagaaagaa atatgatcaa ctgcagaact
     1681 ttctcaattc tgcggattat tttcaagatg agaagtttta attatagcat gcttccttca
     1741 tgaagagaag attttataaa tttctgtaaa tgcgaagacc atgagtttta tttttctgtg
     1801 ttatgtatca ttggttttat attctatgta tgtctttgtg ggaaaatatc ttatttatat
     1861 gctcatctaa ttttcataaa atgccaaagt gaagcctaat aacagtttca tagatttaca
     1921 tggagaacat tagctttgtg gttcagaagt ccctcagtgt attatagtca cgtggtgatg
     1981 cttttctcac acgtgaccag cagttgaatg tgctatcatg tcctgtcagt ttagtagaaa
     2041 caggctgtgt tacgatatat ttgggctgac ctgaggatgg ctcagtcaat atagtacttg
     2101 tcttacgaac ataaagacct gagttcagtc ccctgtactg gctagttttg tgtcaacttg
     2161 acacagctgg agttaccaca gagaaaggag cttcagttga ggaaatgcct ccataagatc
     2221 caactgtaag gcattttctc aattagtgat caagtgggaa agccccttgt gggtgggacc
     2281 atctctgggc tggtagtctt gggttctata agagagcagg ctgagcaagc caggtgaggc
     2341 aagccagtaa agaacatccc tccatggcct ttgtatcagc tcctgtttcc tgacctgctt
     2401 gagttccagt cctgacttcc tttggtgatg aacagcagta tggaagtgta agccgaataa
     2461 accctttcct ccccaactgc ttcttggtca tgatgtttgt gcaggaatag aaaccctgac
     2521 taagacaaat tggtaccagc agagtggggt attcctgtga caacctgacc atgttttggg
     2581 gaggactgtg gaaggacttt ggaactttgg gcttgaagat ccatccgttg ttaagagctc
     2641 tgtcggatgt tgtgtaggaa cttggaagat aatgttgaga acactgcaga agatggaggt
     2701 ctggtttgtg aaatttcaga gggaaaaatt aaagactctt ttcagggcca ttgctgtttt
     2761 gattgtgaag gttctgtagt tctggttagc tggggctgaa gaatcagctg tgattaacaa
     2821 gataccagaa ctaccaaagc aaaaactttg cattactggg actattgatg ctggttagct
     2881 ggagctaaga aattagcggt gattaagaag agaccagcat cattgaggtg acatcttctg
     2941 ggaagtgttt tctgaaagca caaagaggct gtgttccaga gatggccaag gttgtactcc
     3001 tgatgcagca ggacttggta atatgtaagg gtcacccagg tggtactggt tttgaaggca
     3061 tgaaggggtc acgcaaagca gctgaggctt ggcactgtga gaggccattg gtgaaggtgc
     3121 agcctcagtt gcaattgaag gcccaggact gaaggggtca tgcagtgttt tggagatgcc
     3181 agtaccatga gatgaccacc aagagcatca gcagcagtgg agtacaggca tctggagcct
     3241 agaggatgac gcatgtgcta caaagggcat ggctggagaa gtgacccaag cccttggagg
     3301 agcccagaag atcgtgagtt ggatcccaga cagtggacgg ttggagattg acttttgctt
     3361 ttgattgtga ctgtgccctg atattttccc tcttgaagga agaaactgtt ttagtggagc
     3421 ccacagttaa gagactttta attgtaaaaa gactttggat tttaaaagag atggatattt
     3481 tgaagagatt gaaattttaa gaatatgtaa agactgtggg atgtttaaag ttatttagat
     3541 cttggggatg aataagattg taagggttga ggcttactag tgatgttttt gtgtgtcaag
     3601 ttgacaaggg gtcaattgta ctggctagtt ttgtgtcaac ttgacacagc tggagttatc
     3661 acagagaaag gagcttcagt tgaggaaatg tctccatgag atccaactgt aaggcatttt
     3721 ctcaattagt gatcaagggg gaaaggcccc ttgtgggtgg gaccatttct gggctggtag
     3781 tcttggttct ataagagagc aggctgagca agccagggga agcaagccag taaagaacat
     3841 ccctccatgg cctctgcatc agctcctgct tcctgacctg cttgaattcc agtcctgact
     3901 tcctttgtca atatggaagt gtaagccgaa taaacccttt cctccccatc tgcttcttgg
     3961 tcatgatgtt tgtgcaggaa tagaaaccct gactaagaca gtcccccaaa ccatatttaa
     4021 aatagagcca ggcatgatgg aatgtacttg taatccccac gctgggaggc aaagatgagg
     4081 cagatccctg agggtgttgg ccaggcaccc agcctactca tcagtgagag accctgtctc
     4141 aaaaaacaag aatatgtggt gcttgtaagt gacaccaagg ctatcctctg agctcagcat
     4201 gcacgcagac acaaatagtc atgtgcccac acatttgaac aaccacacct gaaccttcac
     4261 atccacagta tatatgcatg tgtatatact tacatagtga gacttatacc tatatgtatg
     4321 tatgtgttct tgtacccctt ggcaatatta agtaatcttc agtaataaat gtctagttaa
     4381 tgtttcctca atcagtgagt catggaagta gcttcaggcc tccatgcatt cagtatccta
     4441 gcctcagagt gagaccatag ctcatctatt ccaggttgag aaatgtttcc ttctgctaaa
     4501 gtttccctga taaatagatg aatcggctca gggtctttca attctcatgt tcagggagaa
     4561 cttcttaata tatatatttt aattgtgtat aatgttcttt cttgtttctg tacaatttta
     4621 tgtgtagtat attaaagatt atgatatgat tttcaccata a
//
