LOCUS       NM_001165929            1651 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus coiled-coil domain containing 78 (Ccdc78), mRNA.
ACCESSION   NM_001165929 XM_354998 XM_914813
VERSION     NM_001165929.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1651)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1651)
  AUTHORS   Maksimova,N., Hara,K., Nikolaeva,I., Chun-Feng,T., Usui,T.,
            Takagi,M., Nishihira,Y., Miyashita,A., Fujiwara,H., Oyama,T.,
            Nogovicina,A., Sukhomyasova,A., Potapova,S., Kuwano,R.,
            Takahashi,H., Nishizawa,M. and Onodera,O.
  TITLE     Neuroblastoma amplified sequence gene is associated with a novel
            short stature syndrome characterised by optic nerve atrophy and
            Pelger-Huet anomaly
  JOURNAL   J Med Genet 47 (8), 538-548 (2010)
   PUBMED   20577004
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134908.5.
            
            On or before Sep 30, 2009 this sequence version replaced
            XM_914813.2, XM_354998.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-126               AC134908.5         160515-160640
            127-243             AC134908.5         160797-160913
            244-330             AC134908.5         161002-161088
            331-447             AC134908.5         161313-161429
            448-536             AC134908.5         161687-161775
            537-615             AC134908.5         161888-161966
            616-741             AC134908.5         162052-162177
            742-917             AC134908.5         162631-162806
            918-999             AC134908.5         162933-163014
            1000-1079           AC134908.5         163174-163253
            1080-1146           AC134908.5         163721-163787
            1147-1247           AC134908.5         163860-163960
            1248-1651           AC134908.5         164045-164448
FEATURES             Location/Qualifiers
     source          1..1651
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.89 cM"
     gene            1..1651
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /note="coiled-coil domain containing 78"
                     /db_xref="GeneID:381077"
                     /db_xref="MGI:MGI:2685784"
     exon            1..126
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..1350
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 78"
                     /protein_id="NP_001159401.1"
                     /db_xref="CCDS:CCDS50035.1"
                     /db_xref="GeneID:381077"
                     /db_xref="MGI:MGI:2685784"
                     /translation="MDQRPELLSSMEYVASPDPKPGVPLRVAENVAPGAEDWLPSASG
                     HLAWATSLETEHQTHLELSEEQRLQISKELVDLQIATHHLREQHEAEVFELRREILRL
                     ESRVLELELHGNGACQGHKVQPMANLGQHQVPPLEPPGGQQKLQEELKWLLEHHRARQ
                     QALETQVGVLSQQLQGAREEARTTGQQLASQAMVLASCKGQLRQAEAENTQLQLQLKK
                     MNEEYAVRLQHYARETVENASSTNQAALQAFLESTLQDIRAAHRTREQQLAQAARTYR
                     KRLADLNQRQELLLTTCRATFATAINLEPLPMHWATELSHPRENEYGRHRTLLLYPEK
                     GSGETSKENKSQPLALDTASWAQIQQRLQDFSQDTQAELERERAQLMVRATMAEQQLS
                     ELQEYVDQHLGRYKQEILKLRKLVNIGDPQGVEAVSSPGSGGARL"
     exon            127..243
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     exon            244..330
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     exon            331..447
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     exon            448..536
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     exon            537..615
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     exon            616..741
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     exon            742..917
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     exon            918..999
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1079
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1146
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     exon            1147..1247
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     exon            1248..1651
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1630..1635
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /note="hexamer: AACAAA"
     polyA_site      1648
                     /gene="Ccdc78"
                     /gene_synonym="Gm938; Gm950"
                     /note="major polyA site"
ORIGIN      
        1 acttccagca agagtcagga agcaagccac tatcagatgg atcagaggcc agaacttctt
       61 tcctctatgg agtatgtggc atctccagac cccaagccag gggtcccact tcgagttgca
      121 gagaacgttg ctccaggagc tgaggactgg ctgccaagtg cttctgggca cctagcctgg
      181 gccactagcc tggagacaga gcatcagaca catctggagc tgagtgaaga acagcggttg
      241 cagatttcta aggagctagt tgatctgcag attgcaaccc accacctgcg cgaacagcat
      301 gaagctgaag tctttgagct gaggagggaa attcttcgac tggaaagtcg ggtgctagag
      361 ctagaactgc atggaaatgg tgcctgccag ggacataaag tccaaccaat ggccaatctg
      421 gggcaacacc aggtgccacc attagagcct ccaggaggcc agcagaagct gcaggaggaa
      481 ctgaaatggc ttctggagca tcacagagcc aggcagcagg cactggagac acaagtggga
      541 gtcctaagcc agcagttgca gggagcccga gaggaagcca ggacaactgg tcagcaactg
      601 gcttcccaag ccatggtgct ggcctcctgt aagggtcagc tccggcaggc tgaggctgaa
      661 aacactcagc tgcagctcca gctgaagaag atgaacgagg agtatgctgt ccggctgcag
      721 cactatgcca gagagacggt ggagaacgcc agtagcacaa atcaggcggc ccttcaagct
      781 ttcctggagt ccactctgca ggacattagg gctgcacacc gaacccgaga gcaacagctg
      841 gcccaagctg cccggaccta ccgaaagcgc ctggcagatc tgaaccagag gcaggagttg
      901 ctgctaacca cctgcagggc tacctttgca acagccatca acctggagcc attacccatg
      961 cactgggcca ctgaactcag ccacccaaga gaaaacgagt atggccgaca taggacactg
     1021 ctactgtacc cagagaaggg atctggtgaa acttccaagg agaacaagtc acagccactg
     1081 gccctagaca ctgcatcctg ggcccaaatc cagcagaggc tgcaggactt ctcccaggac
     1141 actcaggcag agctagaacg ggaacgggca cagctgatgg tccgggccac catggcagag
     1201 cagcagcttt ctgagctaca ggagtatgtg gaccagcact tgggcaggta caagcaggaa
     1261 atcttgaaac tgaggaagtt ggtgaatatt ggagatcccc aaggagtaga agctgtatct
     1321 tcgccgggta gtggtggcgc acgactttaa tcccagcact ccggaggcag aggcagaggc
     1381 aggcagattt ctgagttcga ggccagcctg gtctacagag tgagctccag aacagccagg
     1441 gctatacaga gaaaccctgt ctcaaaaaaa aaaaaaaaaa aaaaaaaaaa gctgtatctt
     1501 ccactaggcc tcagcgccca aggactcaga gtcactagct agtctcccag aaaaatctca
     1561 aaagaaatct ctttacagcc agcatggaac cctctggaca ccctgcccca ggaagtgatt
     1621 cctggaacaa acaaaagtca ggattgaacc c
//
