LOCUS       NM_001384199            1955 bp    mRNA    linear   ROD 04-AUG-2024
DEFINITION  Mus musculus coiled-coil domain containing 63 (Ccdc63), transcript
            variant 6, mRNA.
ACCESSION   NM_001384199 XM_006530388
VERSION     NM_001384199.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1955)
  AUTHORS   Young,S.A., Miyata,H., Satouh,Y., Kato,H., Nozawa,K., Isotani,A.,
            Aitken,R.J., Baker,M.A. and Ikawa,M.
  TITLE     CRISPR/Cas9-Mediated Rapid Generation of Multiple Mouse Lines
            Identified Ccdc63 as Essential for Spermiogenesis
  JOURNAL   Int J Mol Sci 16 (10), 24732-24750 (2015)
   PUBMED   26501274
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140353.2.
            
            On Jun 5, 2020 this sequence version replaced XM_006530388.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.122215.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849378 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-45                AC140353.2         151239-151283       c
            46-162              AC140353.2         149607-149723       c
            163-395             AC140353.2         149041-149273       c
            396-585             AC140353.2         146725-146914       c
            586-705             AC140353.2         144244-144363       c
            706-887             AC140353.2         142044-142225       c
            888-1069            AC140353.2         140236-140417       c
            1070-1290           AC140353.2         136128-136348       c
            1291-1365           AC140353.2         132452-132526       c
            1366-1558           AC140353.2         130178-130370       c
            1559-1762           AC140353.2         128490-128693       c
            1763-1955           AC140353.2         127373-127565       c
FEATURES             Location/Qualifiers
     source          1..1955
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 62.17 cM"
     gene            1..1955
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /note="coiled-coil domain containing 63"
                     /db_xref="GeneID:330188"
                     /db_xref="MGI:MGI:3607777"
     exon            1..45
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            46..162
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             154..1902
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /note="isoform 2 is encoded by transcript variant 6;
                     coiled-coil domain-containing protein 63"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 63 isoform
                     2"
                     /protein_id="NP_001371128.1"
                     /db_xref="GeneID:330188"
                     /db_xref="MGI:MGI:3607777"
                     /translation="MPVKKYRWTTTVGRVGILFLCLAQMKKVRRKGSSGLSELSEKAR
                     EQLAQAELRKLRQQFRKMVDSRKSFNFRHQRMIAGQYKEIETLKAEQAETTMLLSLVK
                     SPKNLDINQKNFMELRFLLQTKGDYEALISSMKVLLGELDDKIVQMERKITNQRQLFL
                     RTQEANNPKRLQRQIHVLESRLNLVTVHFDTMLTSNSQLRKEIEDLLFEKAAYDHVYQ
                     QLQRRLQTQKKTMNVAIEQSAQAYEQRVEAMARMAAMKDRQQKDISQYNLEIRELERL
                     YDHETKLKSFLLAKLNDRSEFEDQAKKQEDVKSKKLGKKGKGESFASYEVAHLRLLKL
                     AENGDLNQLTEDFLAKEEKNFARFTYVTELNNDMETMHKKTQRIQDDIINLRSQQQTS
                     HEGTRSILKQMEEKLRKTTQEADIYETKYKEMSKTLEYLKNSVEKMFKKINCDATEIL
                     GKLGESGKVTDINLQQYFAIIEKKTNDLLLLESFRRLQEAEGPDVDVPQPFVNPFWGG
                     SALLKPPEPIRVVLPVFGADSFSDKLEEVDSPLDHSTLQQMVLENFLQRERTKELQDT
                     MSEKGDEIRLKKKVIG"
     exon            163..395
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            396..585
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            586..705
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            706..887
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1069
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1070..1290
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..1365
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1558
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1559..1762
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..1955
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1936..1941
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1955
                     /gene="Ccdc63"
                     /gene_synonym="4921511C16Rik"
                     /note="major polyA site"
ORIGIN      
        1 agacacacga gccgccacta ccgggagccg cgggagccgt gggtggacat tgcagacaga
       61 ggagacaaag agagacggag aaagaggtgg gcttgctggc tttgacctcc aggacccagt
      121 gtctaagcag aagggaagct cagatccatc tcaatgccag tgaaaaaata cagatggact
      181 accactgtag gtcgtgtggg catcctcttt ctctgtcttg cccagatgaa gaaagtcagg
      241 aggaagggct cttcaggcct ttcggaactt tccgagaagg ccagggagca gctcgcccag
      301 gcagagctac ggaaactgag gcagcagttc cgcaagatgg tagacagccg caagtccttc
      361 aacttccgcc accagcgtat gatcgccggc caatacaagg aaatagagac tctgaaagct
      421 gaacaggccg agaccaccat gcttctaagc ctcgtgaagt ctccgaagaa cctggacatc
      481 aaccagaaaa acttcatgga actacgcttc ctgctgcaga ccaaggggga ctacgaggcg
      541 ctcatctcct ccatgaaggt gctgctggga gaactggatg ataagatcgt tcagatggag
      601 agaaagatca cgaaccagag acagctcttc ttgaggacac aagaggccaa taatcccaag
      661 agactgcaga gacagatcca tgttctggag tcccgactga acctggtcac tgtccacttt
      721 gacacgatgc tgacctctaa ctcccagctc cggaaggaga ttgaggatct cctctttgag
      781 aaggccgcct acgaccacgt ctaccagcag cttcagcggc gtctgcagac acagaagaag
      841 accatgaacg tggccattga gcagtctgcc caggcctatg agcagagagt ggaggccatg
      901 gctcggatgg ctgccatgaa ggaccgccag cagaaagaca tctctcagta caacctggag
      961 atccgggaac tggaacgtct atatgatcac gagacgaaac tcaagtcctt cctgctggcc
     1021 aagcttaacg accgctctga atttgaggac caggccaaga agcaggaaga tgtcaaatcc
     1081 aagaagcttg ggaagaaggg gaagggcgag agtttcgcga gctatgaggt ggcgcacctg
     1141 cggctgctga agctggcgga gaacggggac ctgaaccagc tcaccgagga tttcctggcc
     1201 aaggaggaga agaattttgc tcgtttcact tatgtcaccg agctcaacaa tgacatggag
     1261 accatgcaca agaagaccca gcggatccag gatgacatca tcaacttgcg gtcacagcag
     1321 cagacctccc atgagggcac ccggagcatc ctgaaacaga tggaggagaa actgagaaag
     1381 accacgcagg aagcggacat ttatgagacc aaatacaagg agatgagcaa gaccctggag
     1441 tatctcaaga actcggtgga gaagatgttt aagaagatca actgcgatgc cactgagatc
     1501 ctgggcaagc tgggcgagtc cgggaaggtc acggacatca atctgcagca gtattttgct
     1561 atcatagaaa agaagacaaa tgacctgctg cttctagagt ccttccggcg cctgcaggag
     1621 gcagaggggc ccgatgtcga tgtcccacaa ccctttgtca accccttctg gggcggctct
     1681 gccctcctca agcccccaga gcccataagg gttgtgctgc ctgtgtttgg ggcagactcc
     1741 ttcagtgaca aacttgaaga ggtggactct cctctggacc acagtaccct ccagcagatg
     1801 gtcttggaga acttccttca gagggaacgc acaaaagaac tacaggacac catgtcagag
     1861 aagggggacg agataaggct caagaagaag gtgataggct gagcctcgtg ggtgcctgta
     1921 ttccacacca gagagaataa atgttttctt gctga
//
