LOCUS       NM_026009               3270 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus coiled-coil domain containing 47 (Ccdc47), mRNA.
ACCESSION   NM_026009
VERSION     NM_026009.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3270)
  AUTHORS   Yamamoto,S., Yamazaki,T., Komazaki,S., Yamashita,T., Osaki,M.,
            Matsubayashi,M., Kidoya,H., Takakura,N., Yamazaki,D. and
            Kakizawa,S.
  TITLE     Contribution of calumin to embryogenesis through participation in
            the endoplasmic reticulum-associated degradation activity
  JOURNAL   Dev Biol 393 (1), 33-43 (2014)
   PUBMED   25009997
  REMARK    GeneRIF: these findings suggested that calumin serves to maintain
            the yolk sac integrity through participation in the ERAD activity,
            contributing to embryonic development.
REFERENCE   2  (bases 1 to 3270)
  AUTHORS   Konno,M., Shirakawa,H., Miyake,T., Sakimoto,S., Nakagawa,T. and
            Kaneko,S.
  TITLE     Calumin, a Ca(2)-binding protein on the endoplasmic reticulum,
            alters the ion permeability of Ca(2) release-activated Ca(2) (CRAC)
            channels
  JOURNAL   Biochem Biophys Res Commun 417 (2), 784-789 (2012)
   PUBMED   22197811
  REMARK    GeneRIF: These results reveal a novel mechanism for the regulation
            of Ca(2+) release-activated Ca(2+) channels by calumin.
REFERENCE   3  (bases 1 to 3270)
  AUTHORS   Zhang,M., Yamazaki,T., Yazawa,M., Treves,S., Nishi,M., Murai,M.,
            Shibata,E., Zorzato,F. and Takeshima,H.
  TITLE     Calumin, a novel Ca2+-binding transmembrane protein on the
            endoplasmic reticulum
  JOURNAL   Cell Calcium 42 (1), 83-90 (2007)
   PUBMED   17204322
  REMARK    GeneRIF: observations suggest that calumin plays an essential role
            in ER Ca2+ handling and is also implicated in signaling from the
            ER, which is closely associated with cell-fate decision
REFERENCE   4  (bases 1 to 3270)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   5  (bases 1 to 3270)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   6  (bases 1 to 3270)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 3270)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ157793.1, AK078812.1, AK011882.1 and AL596331.15.
            
            On Feb 10, 2007 this sequence version replaced NM_026009.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660819.108762.1,
                                           SRR1660813.152661.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                CJ157793.1         1-23
            24-668              AK078812.1         3-647
            669-2158            AK011882.1         606-2095
            2159-3270           AL596331.15        207794-208905       c
FEATURES             Location/Qualifiers
     source          1..3270
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 68.89 cM"
     gene            1..3270
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /note="coiled-coil domain containing 47"
                     /db_xref="GeneID:67163"
                     /db_xref="MGI:MGI:1914413"
     exon            1..219
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     exon            220..500
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     CDS             237..1688
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /note="coiled-coil domain-containing protein 47;
                     adipocyte-specific protein 4; PAT complex subunit CCDC47"
                     /codon_start=1
                     /product="PAT complex subunit CCDC47 precursor"
                     /protein_id="NP_080285.2"
                     /db_xref="CCDS:CCDS25551.1"
                     /db_xref="GeneID:67163"
                     /db_xref="MGI:MGI:1914413"
                     /translation="MKAFYAFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFED
                     VMEDSVTESPQRVISTEDDEDEATVELEGQDESQEGDFEDADTQEGDTESEPYDDEEF
                     EGYEDKPDTSSNKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKN
                     SRLAQAWFNSHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGM
                     LIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALLRLQKEM
                     QDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDTKMVHFLTHYADKIESVHFS
                     DQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMESLLPLMNMVIYSIDK
                     AKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP
                     EKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM"
     exon            501..608
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     exon            609..783
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     exon            784..905
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     exon            906..971
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1073
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..1184
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1270
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1329
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     exon            1330..1439
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1607
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     exon            1608..3270
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2109..2114
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /note="hexamer: AATAAA"
     polyA_site      2145
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
     regulatory      3252..3257
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /note="hexamer: ATTAAA"
     polyA_site      3270
                     /gene="Ccdc47"
                     /gene_synonym="2610204L23Rik; asp4; calumin"
                     /note="major polyA site"
ORIGIN      
        1 gcgcgcaggc gcaaactagc tgtacgcatt ctacgtaacg gacggctgaa gctacgtgaa
       61 gagtagggtg ccgtgactga gctacctgtt ctgggctgtt cagtgacatc gcggcccgca
      121 gattatcttt gcgacctgaa gacagaaacc agacaaaggc aggctggttg gaggtagtgg
      181 cctcaggagc cccgggcccg gttgcagcct cgggtgcagc ttgtttttaa ggtgcaatga
      241 aagccttcta tgctttctgt gtggtcctct tggtgtttgg gagtgtctcg gaagccaagt
      301 ttgatgattt cgaagatgag gaagacatag tagagtatga tgataatgat tttgctgagt
      361 ttgaggacgt catggaagat tctgttacgg agtcgcctca gcgagtgatc agcactgaag
      421 atgacgagga cgaggccacc gtggagttgg aagggcagga tgaaagccaa gaaggtgatt
      481 tcgaagatgc agatacccag gagggagata cagaaagtga gccatatgat gatgaggaat
      541 ttgagggtta tgaagacaaa ccagatacct cttctaacaa aaataaagat ccaataacaa
      601 ttgttgatgt tcctgcacac ctccagaaca gttgggagag ttattaccta gaaattttga
      661 tggtgactgg tctgcttgcc tatatcatga actacatcat tgggaagaat aaaaacagcc
      721 gacttgctca ggcctggttt aactctcata gagagctttt ggagagcaat tttacattag
      781 tgggggatga tgggactaac aaagaagcca caagcacagg gaagttgaat caggagaatg
      841 agcacatcta taacctgtgg tgttctggcc gagtgtgctg tgaaggcatg cttatccagc
      901 tgaggttcct taagagacaa gacttactta atgtcctggc ccggatgatg aggccagtga
      961 gtgatcaagt gcaaataaaa gtaacaatga atgacgagga catggacaca tacgtgtttg
     1021 ctgtcggcac tcgcaaagct ttgctgcgac tacagaaaga gatgcaggat ctgagtgagt
     1081 tttgcagtga taaaccaaag tctggagcaa agtatggact gccagactct ttggccattc
     1141 tgtcagaaat gggagaagtc acagagggaa tgatggatac aaagatggtt cattttctta
     1201 cacactatgc tgataagatt gaatctgttc atttttcaga ccagttctct ggtccaaaga
     1261 ttatgcaaga ggaaggccag cctttaaagc tgcctgacac caagaggacg ctactgttta
     1321 catttaatgt gcctggctca ggtaacacat acccaaagga tatggagtct ttgctacccc
     1381 tgatgaacat ggtgatttat tctatcgata aagccaaaaa gttccgactc aacagagaag
     1441 ggaaacaaaa agcagataag aaccgggctc gtgtggaaga gaactttctg aagctgacac
     1501 atgtgcagag acaggaggct gcacagtctc ggcgtgagga gaaaaaaaga gctgagaagg
     1561 agcggatcat gaacgaggag gaccctgaga aacagcgcag gctggaagaa gctgctttga
     1621 ggagagaaca aaagaagttg gagaagaagc aaatgaaaat gaaacaaatc aaagtgaaag
     1681 ccatgtagag ctggttgcag aggttgtgtc cttgctgccg ttagctctcc gtccaccgga
     1741 gacaggaaaa gcaggagtct gcacctaaca gtcacgagtc tctgctgact gagagatctt
     1801 tatctcaccc tctcctctcg gtttagagtt ctacagaggt tatagataca atgaaagggc
     1861 tctttcagtt atttccttcc agataatcaa attattttga ttattttata aaaggagcgg
     1921 tatataaagt atgtgtagtt ttaaaatata tttaaattat aatgtgaatc atcagtgcgt
     1981 tactttggtg tttgaagacc gatcatgaaa tttctaggta gattgttgct ctttgtttaa
     2041 actggacagt tgaaataact atggagactg actctaaacc aagaccctaa tatctattgg
     2101 aattgcacaa taaacattgc ttgttttttc tgtgtccaca ttaaacttgt gaaaaaagtg
     2161 gaacgtagaa cactatgtgg tgataaattc agagacttag agcatagtac agcgtatggt
     2221 ttgtgtgtgg gtggtgctat ggcagtatta taggagggaa tctgtcggta ttaggatact
     2281 gtaagtcagt ggaagattct agatgtaggt agtacaggag cagtttctca ttgcctgata
     2341 ctatgagcta atgacactgt gagtgctgga tttgaagtag ttatgtgctt atttttcttg
     2401 agcaagaatg catgacaagg tgaagtgctt cacctagctc cctccgctca gcagcagtca
     2461 ggtggctggg ctctgtgagg tcacagtggt ttgcttgctt gctgcagcct ggtaggtgtt
     2521 catggaggag ctgatctctg tcttaggcgt gcactttgct tccacgcctg cttttatatc
     2581 gtccacaagg ccggtttgta ctttcttgaa acaaataacc aatcgatata cacaaatatg
     2641 cttttaaaaa gtgagctttt tttaaatgaa tcagaatttt gtctgactca tgaggcggaa
     2701 gcgatggtag ggagaggttc ctctctgtgc ataagcattt ggcttgttga gatctctgca
     2761 ttttataaat gcttcctact gagaaagcat ttcttaagtc tttgcttgta ccaggtcatt
     2821 tttgctgggg tgggaaaggg tggtttttgc tttgggagcg ggtagtgggg ttttgttgat
     2881 gctttctgtg ttctgatgca gtaacagtga gttgcggtga aaactgtgtg tgctgttgcc
     2941 ttgggaattg tatggagttt ttcacatggc tttgtgtagg ctaatagaaa tatatgcact
     3001 gggatattca agtgtaatgt tttttaacag ttcacaagtt taagttatta aaaataacac
     3061 aaaattaaat cactttaagg ccagataatt ttagacttaa cattgtttta caaatcttta
     3121 aaatacattt agaatcaaaa tttatgtgtt tagttatcgt ttaagtaata taagctttct
     3181 taaagtccca tacatcagac cgtggcagct aattttgtaa caagcattca tatgaactac
     3241 ctatgacata tattaaactg attgacaaaa
//
