LOCUS       NM_026222               3609 bp    mRNA    linear   ROD 21-AUG-2024
DEFINITION  Mus musculus coiled-coil domain containing 39 (Ccdc39), mRNA.
ACCESSION   NM_026222
VERSION     NM_026222.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3609)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3609)
  AUTHORS   Brown,F.N., Iwasawa,E., Shula,C., Fugate,E.M., Lindquist,D.M.,
            Mangano,F.T. and Goto,J.
  TITLE     Early postnatal microglial ablation in the Ccdc39 mouse model
            reveals adverse effects on brain development and in neonatal
            hydrocephalus
  JOURNAL   Fluids Barriers CNS 20 (1), 42 (2023)
   PUBMED   37296418
  REMARK    GeneRIF: Early postnatal microglial ablation in the Ccdc39 mouse
            model reveals adverse effects on brain development and in neonatal
            hydrocephalus.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3609)
  AUTHORS   Iwasawa,E., Brown,F.N., Shula,C., Kahn,F., Lee,S.H., Berta,T.,
            Ladle,D.R., Campbell,K., Mangano,F.T. and Goto,J.
  TITLE     The Anti-Inflammatory Agent Bindarit Attenuates the Impairment of
            Neural Development through Suppression of Microglial Activation in
            a Neonatal Hydrocephalus Mouse Model
  JOURNAL   J Neurosci 42 (9), 1820-1844 (2022)
   PUBMED   34992132
REFERENCE   4  (bases 1 to 3609)
  AUTHORS   Abdelhamed,Z., Vuong,S.M., Hill,L., Shula,C., Timms,A., Beier,D.,
            Campbell,K., Mangano,F.T., Stottmann,R.W. and Goto,J.
  TITLE     A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal
            motile cilia development in mice
  JOURNAL   Development 145 (1) (2018)
   PUBMED   29317443
  REMARK    GeneRIF: data provide the first evidence for involvement of Ccdc39
            in hydrocephalus and suggest that the proper development of medial
            wall ependymal cilia is crucial for normal mouse brain development.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3609)
  AUTHORS   Solomon,G.M., Francis,R., Chu,K.K., Birket,S.E., Gabriel,G.,
            Trombley,J.E., Lemke,K.L., Klena,N., Turner,B., Tearney,G.J.,
            Lo,C.W. and Rowe,S.M.
  TITLE     Assessment of ciliary phenotype in primary ciliary dyskinesia by
            micro-optical coherence tomography
  JOURNAL   JCI Insight 2 (5), e91702 (2017)
   PUBMED   28289722
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3609)
  AUTHORS   Burnicka-Turek,O., Steimle,J.D., Huang,W., Felker,L., Kamp,A.,
            Kweon,J., Peterson,M., Reeves,R.H., Maslen,C.L., Gruber,P.J.,
            Yang,X.H., Shendure,J. and Moskowitz,I.P.
  TITLE     Cilia gene mutations cause atrioventricular septal defects by
            multiple mechanisms
  JOURNAL   Hum Mol Genet 25 (14), 3011-3028 (2016)
   PUBMED   27340223
REFERENCE   7  (bases 1 to 3609)
  AUTHORS   Li,Y., Klena,N.T., Gabriel,G.C., Liu,X., Kim,A.J., Lemke,K.,
            Chen,Y., Chatterjee,B., Devine,W., Damerla,R.R., Chang,C., Yagi,H.,
            San Agustin,J.T., Thahir,M., Anderton,S., Lawhead,C., Vescovi,A.,
            Pratt,H., Morgan,J., Haynes,L., Smith,C.L., Eppig,J.T.,
            Reinholdt,L., Francis,R., Leatherbury,L., Ganapathiraju,M.K.,
            Tobita,K., Pazour,G.J. and Lo,C.W.
  TITLE     Global genetic analysis in mice unveils central role for cilia in
            congenital heart disease
  JOURNAL   Nature 521 (7553), 520-524 (2015)
   PUBMED   25807483
REFERENCE   8  (bases 1 to 3609)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   9  (bases 1 to 3609)
  AUTHORS   Stottmann,R.W., Moran,J.L., Turbe-Doan,A., Driver,E., Kelley,M. and
            Beier,D.R.
  TITLE     Focusing forward genetics: a tripartite ENU screen for
            neurodevelopmental mutations in the mouse
  JOURNAL   Genetics 188 (3), 615-624 (2011)
   PUBMED   21515572
REFERENCE   10 (bases 1 to 3609)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: Ccdc39 is most abundantly expressed in tissues rich in
            highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154395.4.
            
            On Dec 20, 2022 this sequence version replaced NM_026222.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014839.1, BC138917.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-197               AC154395.4         199089-199285       c
            198-317             AC154395.4         196053-196172       c
            318-464             AC154395.4         194062-194208       c
            465-623             AC154395.4         192790-192948       c
            624-716             AC154395.4         191924-192016       c
            717-845             AC154395.4         191700-191828       c
            846-1037            AC154395.4         187512-187703       c
            1038-1141           AC154395.4         185641-185744       c
            1142-1274           AC154395.4         185009-185141       c
            1275-1469           AC154395.4         181439-181633       c
            1470-1634           AC154395.4         180375-180539       c
            1635-1772           AC154395.4         176361-176498       c
            1773-1981           AC154395.4         174792-175000       c
            1982-2105           AC154395.4         171812-171935       c
            2106-2265           AC154395.4         170896-171055       c
            2266-2372           AC154395.4         170396-170502       c
            2373-2513           AC154395.4         169639-169779       c
            2514-2690           AC154395.4         169337-169513       c
            2691-2767           AC154395.4         169174-169250       c
            2768-3609           AC154395.4         167343-168184       c
FEATURES             Location/Qualifiers
     source          1..3609
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 16.32 cM"
     gene            1..3609
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /note="coiled-coil domain containing 39"
                     /db_xref="GeneID:51938"
                     /db_xref="MGI:MGI:1289263"
     exon            1..197
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     CDS             108..2921
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 39"
                     /protein_id="NP_080498.1"
                     /db_xref="CCDS:CCDS17304.1"
                     /db_xref="GeneID:51938"
                     /db_xref="MGI:MGI:1289263"
                     /translation="MCSEFLSELHWEDGFAIPVANQENKILEDQLAKLREEKSNLQDQ
                     LHDYEERINSMTSHLKNVNQEFLFTQSLYKARESEIESEEHFKAIAERELGRVKNETQ
                     LLEKEMAIIRERKSQMENNIFKTTQKLDDLKCQMNWDQQALEAWLEESAHKDSDSLTL
                     QKYSQQDDNKIRALTLQLEKLTMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHL
                     ERQELIQQWENTIEQMQRRDQEIDNCALALSRIKQEAREKEGVVKEKIKFLENEVENN
                     IEYERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLNRTSSDLQALRKNISK
                     VKKDIFDETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVE
                     VQLGIVKDVLFKKVQELQNEIAKEKALVSEIEGTRSSLKHLNKQLHKLDFETLKQQEI
                     MYSQDFYIQQVERRMSRLKGEINSEEKQALEAKILELKKTMDEKKSTLSLLESQIKKL
                     HNDLYFIKKSNGKNNDEKESLMNKISELNLFIDRSEKELSKAKAVKEDMMIEDNLLKL
                     QVKRARELLYSKAEEVLSLEKRKQQLGKDMEERAEEIKVHKAMLTSQIRCVEQQRKTM
                     SSEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQSYYVIKAAQEKEELQREGDSLD
                     AKINKAEKEIYALQNTLQVLNSCNSNYKQSFKKVTPSSDEYALKIQLEEQKRTADERY
                     RCKQRQIRELQEDIQSMENTFEVIGHLANNAKEKLTEKQTLAFQLRKETEEQKPKLQR
                     ITKQCGRLRREIRILKQTDNETLEEQDIQLREIIQFHKDIDQMLVNAMENAEIHAIFK
                     TYFEQNGLELPTARGPSSRSSSQSSSLSSFRSLEDVTLQSPPTAKVIQLRFPEPPPAT
                     NDSSRSASSGSNSNIPKEKKLSK"
     exon            198..317
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            318..464
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            465..623
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            624..716
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            717..845
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            846..1037
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1141
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            1142..1274
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            1275..1469
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            1470..1634
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1772
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            1773..1981
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            1982..2105
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            2106..2265
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            2266..2372
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            2373..2513
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            2514..2690
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            2691..2767
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     exon            2768..3609
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3585..3590
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /note="hexamer: AATAAA"
     polyA_site      3609
                     /gene="Ccdc39"
                     /gene_synonym="4921507O14Rik; b2b1304Clo; b2b1735Clo;
                     b2b2025.1Clo; D3Ertd789e; prh"
                     /note="major polyA site"
ORIGIN      
        1 gcctggctgt tgctagggcc gcggaataca gacggttagg cttggctgcg agctccaggg
       61 aacggttttg ggtggcttgt ctgtgattcc tttgagcctc gtacgccatg tgcagtgagt
      121 tcttgtcaga gctgcactgg gaagatgggt tcgccatccc cgtggccaat caggagaaca
      181 agatcctgga ggatcagttg gcaaagctcc gagaggaaaa atcaaacttg caagatcagc
      241 ttcatgacta tgaagaacga attaattcta tgacttctca ccttaaaaat gtgaatcagg
      301 aatttttatt tacacagtct ctttacaaag caagggagag tgagatcgag agcgaagaac
      361 attttaaggc cattgctgaa agagagctgg gccgagtcaa gaatgagacc caactgctgg
      421 agaaggagat ggcgatcatc cgggagcgca agagccaaat ggaaaacaat atatttaaaa
      481 ctactcaaaa gctggatgac ttgaaatgtc agatgaactg ggaccagcaa gccttggagg
      541 cctggctgga agaatcggct cacaaagaca gtgactctct gacccttcag aagtactctc
      601 agcaagacga taacaaaatc agggccctga ctctgcagtt agaaaagctg accatggagt
      661 ataacgagaa gaggaagctt ctagacagtg aactgacaga gacgctaagt gcgcagttag
      721 aattagataa agctgcacag gatttccgga agattcactt agaacggcag gagctcattc
      781 agcagtggga gaacaccatt gagcagatgc agaggcggga tcaggagata gacaactgtg
      841 ccctggcatt atcacgaata aagcaggaag caagagaaaa agaaggcgtg gtgaaagaga
      901 agatcaagtt tctggaaaat gaggttgaga acaacataga atacgagaga aaaatttctg
      961 ttgctgagcg gaaagtgtcc aagtgcagga tggactacca gcgtcacgaa ggcaacagaa
     1021 gtcagctgaa ggatgagctg gatactttaa aaaccactct caacagaaca tccagtgact
     1081 tacaagctct gaggaaaaac atttccaaag taaagaagga catctttgac gaaacattaa
     1141 gattacaaaa acttaaacat cacaatgagg ttgtaaaaca taaattaaag atgataactg
     1201 agaagaccct atctattgaa gagaaagcta ccaacatgga agacatgctg aaggaggagg
     1261 agaaaggcct gaaggaagtg gaggttcaat tgggcatagt aaaagacgtg ttatttaaga
     1321 aagtccaaga gttacagaac gagatagcga aagagaaagc cctggtatca gaaattgaag
     1381 gaacccgttc ctccctgaaa catcttaaca aacagttaca caaactggat tttgaaaccc
     1441 tgaagcagca ggaaattatg tacagtcagg atttttacat tcagcaagta gaacgcagaa
     1501 tgtcacgatt aaaaggagaa attaattcag aggaaaagca agcccttgaa gcaaaaatcc
     1561 ttgaacttaa gaagacaatg gatgagaaaa aatccacact ttcccttttg gaatcccaga
     1621 tcaagaagct ccataatgac ctctacttca ttaagaaatc aaatggtaaa aacaatgatg
     1681 agaaagagtc tctcatgaat aaaataagtg aactgaacct ttttattgac agatctgaga
     1741 aggaactgag caaagccaaa gctgtgaaag aggatatgat gatcgaggac aatcttttaa
     1801 agcttcaagt taaacgtgct cgagaattgc tttacagcaa ggcagaggaa gtcctttctc
     1861 tagagaaaag gaaacagcag ctgggcaaag acatggaaga gagagctgaa gaaattaaag
     1921 tgcacaaagc catgcttacc tcacagatca gatgtgttga acagcagcga aaaactatga
     1981 gttctgaatt tcatgagcgg ctaagtaaaa ttgataagct taagaataga tatgaaattc
     2041 ttactgttgt catgctgcct cctgaaggag aagaggagaa aacacagtcc tattatgtaa
     2101 taaaggctgc tcaagaaaaa gaagaacttc aaagggaagg tgatagcttg gatgctaaga
     2161 tcaacaaagc tgaaaaagaa atctatgctt tgcaaaacac cttgcaagta cttaacagct
     2221 gcaacagcaa ttataagcaa tctttcaaaa aagtgactcc gtcaagtgat gagtatgcat
     2281 taaaaattca actagaagaa caaaaaagaa ctgcagatga gagatacaga tgcaaacaaa
     2341 ggcagatcag agaacttcaa gaagatatcc agagcatgga aaatactttt gaagttatag
     2401 gacacttagc aaataatgcc aaagagaaat taacagagaa acaaacactt gcatttcaac
     2461 ttcgtaagga gactgaggag cagaagccga aattgcagcg aataactaag cagtgtggaa
     2521 gactcagaag agaaatccgc attttgaaac aaacagataa tgaaactcta gaagaacagg
     2581 acattcagct ccgtgagatc atacagtttc acaaggacat tgaccaaatg ttagttaatg
     2641 ccatggaaaa tgcagaaatt catgccatct ttaaaacata ttttgagcag aacgggttag
     2701 aactacctac agcaagaggc ccgagctcga gatcttcttc ccagtcttcc tccctttcat
     2761 cattcaggtc gctcgaggat gtaactctcc agtctccccc cacagctaaa gtgatacagc
     2821 tcagattccc agagcctcct ccagcaacaa atgacagttc taggtcagct agtagtggca
     2881 gtaattccaa cattcctaaa gaaaaaaagc tcagcaaatg aacatgcttt tttttaaaaa
     2941 aaaatctttt tatacattta gaacacaaat gaaaatctta ttaatagtta agtctctctc
     3001 tttttctggg gcttcattta ttaatgatgc aggcttacta aaatactacc aaaagtacag
     3061 agcagacaaa agttctgtac agtggctata agagctgtct gagaaaagaa caaagggagt
     3121 tttgtgtttg tttttttcct actgttttat ttatagagaa ggaaaactgc agaaccttag
     3181 ccaagccaca tgtgacaaag cagagggaaa taagcaggtt tttttttttt ttactagaac
     3241 atgtctacag tgttagatgt tttatgaagt aacacattta taagattctt tcactaatac
     3301 acttctaaag atttattcta tctctcaata atgaagtttt catttactct agatcaccaa
     3361 actacctttt aaaataaaaa ataagcgaac aactgtattc ttcagatgtt tttaaggggg
     3421 ttaacatgag ggaggagctt gggaaagacc atcttttgtt tatttgtact gtttataatg
     3481 tgtaaccaaa acacagcatc attcccactc cctcaggaaa aagtttagta agaaagacac
     3541 tgtttatgta tatgtacata tgcatttgtc tctatatgtg cacaaataaa gtgaaaccta
     3601 agctgttaa
//
