LOCUS       NM_001166282            3124 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Mus musculus coiled-coil domain containing 33 (Ccdc33), transcript
            variant 1, mRNA.
ACCESSION   NM_001166282
VERSION     NM_001166282.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3124)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3124)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 3124)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 3124)
  AUTHORS   Kaczmarek,K., Niedzialkowska,E., Studencka,M., Schulz,Y. and
            Grzmil,P.
  TITLE     Ccdc33, a predominantly testis-expressed gene, encodes a putative
            peroxisomal protein
  JOURNAL   Cytogenet Genome Res 126 (3), 243-252 (2009)
   PUBMED   20068295
  REMARK    GeneRIF: Data show that Ccdc33 encodes a putative peroxisomal
            protein and is predominantly expressed in male germ cells.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158996.2.
            
            On Feb 2, 2022 this sequence version replaced NM_001166282.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK145264.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-394               AC158996.2         39141-39534
            395-723             AC158996.2         40338-40666
            724-840             AC158996.2         40766-40882
            841-1004            AC158996.2         59291-59454
            1005-1138           AC158996.2         71293-71426
            1139-1248           AC158996.2         75900-76009
            1249-1340           AC158996.2         80340-80431
            1341-1461           AC158996.2         81311-81431
            1462-1591           AC158996.2         88003-88132
            1592-1725           AC158996.2         88747-88880
            1726-1881           AC158996.2         99573-99728
            1882-2041           AC158996.2         124254-124413
            2042-2133           AC158996.2         124658-124749
            2134-2265           AC158996.2         124973-125104
            2266-2359           AC158996.2         125194-125287
            2360-2508           AC158996.2         126206-126354
            2509-2715           AC158996.2         126707-126913
            2716-2802           AC158996.2         127549-127635
            2803-2916           AC158996.2         128008-128121
            2917-3124           AC158996.2         129086-129293
FEATURES             Location/Qualifiers
     source          1..3124
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 31.63 cM"
     gene            1..3124
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /note="coiled-coil domain containing 33"
                     /db_xref="GeneID:382077"
                     /db_xref="MGI:MGI:1922464"
     exon            1..394
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..3042
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     speriolin-binding factor; coiled-coil domain-containing
                     protein 33"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 33 isoform
                     1"
                     /protein_id="NP_001159754.1"
                     /db_xref="CCDS:CCDS52811.1"
                     /db_xref="GeneID:382077"
                     /db_xref="MGI:MGI:1922464"
                     /translation="MAFRGPDPYLPASLLSQRLKAGEKTLDLEFEILSVGFNEEGRYA
                     LRLSAENPLQAGSSAGVQLQVNDGDPLPACSAVTEVIEQQDPGQSLTFTRNKFIFTLP
                     KGFCKNDGQSDAHLRVEALRLDGSSGQEAQRVGEAIFPIYPRPDEPRMNLTAQDHEDL
                     YRYCGNLALLRASEDPTARHCGGLAYSVAFHVHRDPRSSVSDCQLEPSQPELQTSREA
                     LSDKIEESYMSPFSTDSDQEGLSWEAGPWQHPAQVPEEPQGRLDTSQDPYPAANYLAP
                     CNKETITVTLYGATNLPAGKDGSEPWPYVVVKTTSEKANKHSPQAMTSVTSEPTRAPV
                     WGDTVNVEIQAEDTGREDLILKVMDNKRKKELVSYDIPIKYLRIFHPYQFKLEKVFLR
                     GVNEPLVNSLKPMVVIARVVPNYTEFKARQARRDPASVGLPLTQVSFPISSPMNFDVP
                     RINQNGYPQLSKPGGPPEQPLWNQSFLFQARDGATSFSENTALVLEYYPSASMQSSEP
                     WALNQPLGVSVLPLKSRLYHKMLTGKHLQGLQVERLPIIRPENFLTPNNSKALPTINP
                     KILDENLGAIRESWSMSSLDSTQEMEELQPRDVEMNNYRRAMQKMAEDILALKKQANI
                     LEEENGMLRSHLSQQSIEEQSRAEEENLAVSMKQKLLLNELDMKRLRDRVQHLQNELI
                     RKNDREKELLLLYQAQQPQAAQLRRYQDKLQKMKALEDTVRHQEKVIEKMEQILEERL
                     CERKEPIPSNRPQGKPIMASGIPLGPVGETLAVDLYSMLLAENTRLRTELEKNRQQSA
                     PIILQQQALPVDPRELGAGGDLAERLQDTNGPGHPKSTETLPAQVGVPGGYSTAQAAP
                     GAPAVHKPKINIWSSGGMRTQDFLGGTSDKFNLLAKLEQAQSRILSLENQLEESARHW
                     AREKQNLAIRLQEQQHGFGQPPNSIIIDQPNAGASKNRQQLSKLETSLPSSDKKLNRP
                     SDSQIEISNNQKT"
     exon            395..723
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            724..840
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            841..1004
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1138
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1248
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1340
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..1461
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1462..1591
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1592..1725
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..1881
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1882..2041
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2042..2133
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2134..2265
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2266..2359
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2360..2508
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2509..2715
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2716..2802
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2803..2916
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2917..3124
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3103..3108
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /note="hexamer: AATAAA"
     polyA_site      3124
                     /gene="Ccdc33"
                     /gene_synonym="4930535E21Rik; Gm1117; Tzip1"
                     /note="major polyA site"
ORIGIN      
        1 gtcttctttc cgactggacc caggatggga ctgtgagcag gagagggcag ggctcagcct
       61 ggagttctga ccctggctga agccatggcc tttagaggtc ctgatcccta cctccctgca
      121 tccctgctga gccagcgact gaaggctgga gagaagacac tggacctgga gtttgagatc
      181 ttgagtgtgg gatttaatga ggagggccgg tacgccctga ggctgtcagc tgaaaaccca
      241 ctgcaggcag gctccagtgc tggggtgcag ttgcaagtca atgatgggga cccccttcca
      301 gcctgctcag ctgtcactga ggtcattgag cagcaggatc ctggccagag cctcaccttc
      361 accaggaaca aatttatctt cactctgccc aaagggttct gtaagaatga tgggcagagt
      421 gatgcacatc tgcgtgtgga ggctctgagg ctggatggat cctcaggaca ggaggctcag
      481 agggtaggtg aggccatctt ccccatttac ccacgaccag atgagccccg aatgaacctc
      541 acagcacagg atcatgaaga cctgtaccgc tattgtggca acctggctct tctccgagcc
      601 agcgaggacc ccacagcccg ccactgtggg ggcctggctt acagtgtggc cttccatgtg
      661 cacagggacc ctaggtcctc tgtctcagac tgtcaactgg aacccagcca accagagcta
      721 cagacttcga gggaggccct gagtgacaag atagaagaat cttatatgag cccattcagc
      781 actgacagtg accaggaggg gctcagctgg gaagcaggac cctggcagca tccggctcag
      841 gttcctgagg aaccacaggg ccgcctggat acctcccagg acccatatcc tgccgccaac
      901 tacctggctc cctgtaataa ggagactatc actgtcactc tatatggagc taccaacctt
      961 cctgccggca aggatggctc tgaaccgtgg ccctacgtgg tggtaaaaac cacatcagag
     1021 aaagccaaca aacacagtcc tcaagcgatg acctctgtga cctcagaacc caccagagcc
     1081 cccgtctggg gggacacagt gaatgtggag atccaggcag aggacacagg acgggaagat
     1141 ttgatcctca aggtgatgga caacaagagg aagaaggagc tggtgtccta cgacatcccc
     1201 attaaatacc tgcgcatctt ccacccatac caatttaagt tagaaaaggt ctttcttcga
     1261 ggagtcaacg agcccttagt caacagcctc aagcccatgg tggtaattgc tcgggtagtt
     1321 cccaactata ctgagtttaa ggccaggcag gccaggcggg atcctgcctc tgtggggctg
     1381 cccctcaccc aggtttcctt ccctatctca tcgccaatga actttgatgt gcctcggatc
     1441 aaccagaacg ggtatcctca gctgtccaag cctgggggac ccccagagca gcccttgtgg
     1501 aaccagtcct tcctcttcca agcccgagat ggggccacca gtttctcaga gaacacagcc
     1561 ctggtgctgg agtactaccc ctctgcctca atgcaaagca gtgagccatg ggccctcaac
     1621 cagcccctgg gtgtatcggt gttaccactg aaatctcgtc tataccacaa gatgttgaca
     1681 ggaaaacact tgcaagggct gcaagtggag cggcttccca tcatcagacc agaaaacttc
     1741 ttgacaccaa acaacagcaa ggctctgccc accatcaacc ccaagatcct agatgagaat
     1801 ctgggtgcca tccgtgaatc ctggtccatg agctccttag actccactca ggaaatggag
     1861 gaacttcagc cccgtgatgt ggagatgaac aattaccggc gggccatgca gaagatggca
     1921 gaggacatcc tggcactgaa gaagcaggct aacatcctgg aggaggagaa cggcatgctg
     1981 aggagccacc tgagccagca gagcatagaa gagcagagca gggcggagga agagaacctg
     2041 gcagtgtcca tgaagcagaa gctactgctg aacgaactgg atatgaagag gctgcgagac
     2101 agggtgcagc acctgcaaaa tgagctgatt cggaagaatg accgagagaa ggagctgctg
     2161 cttctgtacc aggctcagca gccccaggct gcacagctga ggcgctacca ggacaagctg
     2221 cagaagatga aggccctgga ggacactgta cggcaccagg agaaggtgat cgagaagatg
     2281 gagcagatat tggaagaaag gctctgtgag aggaaggaac caataccatc aaacaggcca
     2341 caggggaagc ctatcatggc ctcgggcatt cctctgggcc ccgtgggaga gaccctggct
     2401 gttgaccttt actccatgct gctagcagaa aacacgaggc ttcggacaga gctggaaaag
     2461 aaccgccagc agtcagcccc catcattctg cagcagcagg ccctaccggt ggatcccagg
     2521 gagttgggag caggtggaga tttggcagaa aggctacaag acacaaatgg cccgggccac
     2581 cccaagtcca cagagaccct gccagcacag gtgggtgtcc caggaggcta ctccactgcc
     2641 caggctgctc caggtgcccc tgctgtacac aaacccaaaa tcaatatttg gagctctggt
     2701 ggcatgagaa cacaggactt ccttggtggt acttcagaca agtttaacct cctggccaag
     2761 ctagaacaag ctcagagtcg gatcttgtcc ctggaaaacc agctggagga gtcagctcgc
     2821 cactgggcac gagagaagca aaacctggcc attcgtcttc aagagcaaca acacggcttt
     2881 ggacagccac caaactccat catcatagac cagcctaatg ctggagcatc caagaatcgc
     2941 cagcagctct cgaaactgga aacctccctg cccagctcag acaagaagct caacagaccc
     3001 tcagactctc agattgagat ctctaacaac cagaagacct gagaccggag cagatctcct
     3061 tcgccatgtg ctggggattc acgtgccccc aaagacgcct ttaataaaag ctgtcagtca
     3121 ataa
//
