LOCUS       NM_029286               3482 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus coiled-coil domain containing 30 (Ccdc30), transcript
            variant 1, mRNA.
ACCESSION   NM_029286 XM_985783 XM_986832
VERSION     NM_029286.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3482)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3482)
  AUTHORS   Bouma,G.J., Hudson,Q.J., Washburn,L.L. and Eicher,E.M.
  TITLE     New candidate genes identified for controlling mouse gonadal sex
            determination and the early stages of granulosa and Sertoli cell
            differentiation
  JOURNAL   Biol Reprod 82 (2), 380-389 (2010)
   PUBMED   19864314
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ158930.1, AK078362.1 and AK049010.1.
            
            [WARNING] On Jul 9, 2024 this sequence was replaced by NM_029286.3.
            
            On Jul 7, 2012 this sequence version replaced NM_029286.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK078362.1, BC114436.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-274               CJ158930.1         1-274
            275-2534            AK078362.1         202-2461
            2535-2944           AK049010.1         1676-2085
            2945-3482           AK049010.1         2087-2624
FEATURES             Location/Qualifiers
     source          1..3482
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 55.35 cM"
     gene            1..3482
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /note="coiled-coil domain containing 30"
                     /db_xref="GeneID:73332"
                     /db_xref="MGI:MGI:1920582"
     exon            1..386
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            387..577
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             413..2377
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /note="isoform a is encoded by transcript variant 1;
                     coiled-coil domain-containing protein 30; prefoldin
                     subunit 6-like protein"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 30 isoform
                     a"
                     /protein_id="NP_083562.1"
                     /db_xref="CCDS:CCDS38861.1"
                     /db_xref="GeneID:73332"
                     /db_xref="MGI:MGI:1920582"
                     /translation="MCQEGLFRLALSSPRKQTACSLGERRTLAEALGLVDSTLESRRD
                     PNSSLQKEFPQHQDEDQSRAAAPQDCLLRDVECIAQKLEASLEEIHRGAREPREEREQ
                     RTLGDALENARLEIEKLKDNLMKLKESGTTDLQRAREHNQRLDEEILALRNRVRSLDS
                     EKKVLGEMYLTSGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQH
                     NSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEGLRQTQSLK
                     SQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEIKEAKS
                     IEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERE
                     RRKCEEYVKSNQELSEKLSNLQQEKEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQ
                     KVKDRLTHELEIRNKRIKELEDETGKLQQKIEMEKVFQGQIMAQNDILLLEKRKLLEQ
                     VTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRLMQQIGLLEQIIRSIQIRRE
                     EETVITDNAAFEILKKILPLQNSSFSGTGFVLSAENLQETELHKWEGAAAIPKSPEPL
                     SRSQDSESGYINVTSLKETHNTQGDQKPEL"
     exon            578..728
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            729..800
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            801..916
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1096
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1306
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1307..1461
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1462..1606
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1607..1719
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1720..1861
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1862..1998
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1999..2113
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2114..2181
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2182..3482
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2503..2508
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /note="hexamer: ATTAAA"
     regulatory      2514..2519
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2524
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /note="major polyA site"
     polyA_site      2536
                     /gene="Ccdc30"
                     /gene_synonym="1700001O02Rik; 1700041C02Rik;
                     1700111D19Rik; 4930445I03Rik"
                     /note="major polyA site"
ORIGIN      
        1 gctgagtggg gttgccatga cagcggctgg gcggctggag ctgagagtcc cctgctcctt
       61 ctgcgcgctg gcaggaaaat cccacctcag cccggggacg gacctgctct tcccgtggtg
      121 cacattccag atctcttcgg atcgccggtg agctccttcg cgcggtgctg gccggcttcg
      181 gcgtgctcgg cccggtaacg gttggctcag gagaagtgtg ctcttgaccg tccccgaagg
      241 tcccagccac aaaggcccca gagacaccgt tgtgccctgc gcgcggcccg agcgaaagga
      301 ctgtgggact agcttcgtca cacgcaacct tgcatccgga tgaagctctg caggcctttg
      361 gggataccag catccgagat catcaaaagc ccaaacaagg gaagccaacc aaatgtgtca
      421 agaaggcttg ttcagactag ctctgagcag ccccaggaaa cagactgcat gctcactggg
      481 agagaggagg acgctggcag aggccctggg acttgtggac tctacgctgg agtctcgaag
      541 agatccaaac agcagcctac aaaaagaatt tccccagcat caggatgaag accagagtag
      601 agctgcagcg cctcaggact gcctcctgag ggatgtggag tgcatagcac agaagctgga
      661 ggcctcgctg gaggagatcc acaggggagc ccgggagcca cgggaggaga gagaacagag
      721 aacgttaggt gatgcacttg agaatgcccg actggaaata gaaaaactga aagataatct
      781 gatgaaattg aaagaaagtg gtacaactga cctacagaga gcaagggagc ataaccagag
      841 gctggacgag gaaattctgg cattaagaaa ccgggttcga tcacttgact cggagaaaaa
      901 ggtgcttgga gaaatgtatc taacatctgg agagaaaaca agctgccagc accaagggga
      961 actgcgggaa ctgcggcaga acctgcgccg cctgcagatc ctgtgcaact cggctgagaa
     1021 ggagctgcgg tacgagcggg gccggagcct ggacttgaaa caacataaca gtttgctcca
     1081 ggaggagaac atcaagatca aaattgaact caagcaggcc caggagaagt tgctggacaa
     1141 cgccaggctg cactcctcgc tcactgcgga gtggaagcac tgtcagcaga aagtcaagga
     1201 gctcgagctg gaggggctta ggcagacgca gagccttaaa tcccagcagg gcctacagga
     1261 aaagctggcg cgggagaaat ccaaagcagc agaagcacag gaaaagattt tggacctgca
     1321 gcaaaagcta gaccacggaa gacaagtctg cctctcagat gtttgcattt tgcgtaagaa
     1381 gcaacttgag gaagagatta aggaagcaaa gagcatcgag gccaggctgc agcagcagtg
     1441 ccaggaggag cagcagagga ggatcctcct agaccaggac ataaatgagc tccagacaca
     1501 agtgagagcc ttgcaggata aggaggaaca acaggaagca gtcaattccc agcaacaaga
     1561 ggccctacga aaacaactgg agagggagag gagaaagtgt gaagagtatg tcaagagcaa
     1621 ccaggaattg tcagagaaac tatctaactt gcagcaagaa aaggaagctc tatggcaaga
     1681 acacgggcgg tttttggagc aacttggtga tcatgtgaga aactacaaag acaaacacca
     1741 ctgtcacaaa gccaagcttc aaaaggtcaa ggaccgtcta actcacgagc tagagatacg
     1801 gaataagagg attaaagaac ttgaagatga aactggaaaa ctgcaacaga aaattgaaat
     1861 ggagaaagtg ttccagggtc agatcatggc ccagaatgac atcctcctcc tggaaaagag
     1921 gaagcttctg gaacaagtca cagatcaaga agaactgatt tgcagcagca agtgcacgat
     1981 atctgccttc cagagcaagg cgtctttact ggataaagaa aaccagcagt tgcaggagaa
     2041 ctgcctccgg ctcatgcagc aaattggcct cttggaacaa attataagga gcatccagat
     2101 tcgcagagaa gaggaaacag taattactga caacgctgca tttgaaatac tcaaaaagat
     2161 actaccttta caaaactcca gtttctcagg gacaggcttc gtattgtcag ctgaaaatct
     2221 ccaggagact gagctgcaca aatgggaagg cgcagcagca atccccaagt cccccgagcc
     2281 tctttcacgt tcacaggatt cagaaagtgg atatataaat gtgacttctc taaaagagac
     2341 acacaacaca caaggggacc aaaagccaga actatgacct cactggtagc tacaagacta
     2401 ttcatgccta ctaactcaga gcctggatac aaaggtgcaa accgagcagg agcagtctca
     2461 cagaacaccc tggacatcaa caaggattcc tcaaaatcgc ttattaaaca gccattaaaa
     2521 tttttcaaag atgtaattgt ttgatatacc tattgataat gaggttttca attctttttt
     2581 ttttctgtct attagtggtt tgtctctgtg tgtgtgtcca tatactctgt gcatatgcca
     2641 gaaagagggc attggctctc ctgagtctag agtagcagac agctgtgtca tgtgggtgct
     2701 agaaatggaa ccccagtcct ctgttgaacc atctccccag ccctaagaag atttttattt
     2761 tatgtacatt ggtgttttgc ctgcatgtgt ctgtgtgagg gtatcagatc ccctggaact
     2821 ggagttacag gcagttgtga gctgccatgt gggtgctgag catcaaacct gggtcctttg
     2881 aaagaacagt cagtgctctt aactgctgag ccatctctcc aggcctgaag agtttttttt
     2941 ttttaaataa cgttagtaat actccaccag agaagattta tgtttagtaa gcacagaata
     3001 aaaaaaagca ttggtcgtgg tgtggaggga attggccagt ggtgaataaa tagaaaggtt
     3061 tacttagtgc catgcaaggg gtagtgggtg caataaggga cacttgcaac cttctcgcgc
     3121 attgtcagtg caactcactg cgctttgcac ttagtgtcct tattcaagta tgtgttcatt
     3181 ggaggactca acaaaagctt tatgtgtagt gctgttatgt gtttcagatc cccctagaac
     3241 ttgaatgaca gatggttgag acaaatggat gcagggaatt gaacctgggt cctctgggga
     3301 aacagtctgc aactctttac tgccaagaaa tctcaccagc ccctcatttg ggaactttcg
     3361 agataacatc tcatgttatc tcagggtcag cctaccctca aacttgatgg gctagatgac
     3421 cttgaactcc tgaccttcct acttccactt cccaaatact gcgattacaa gcatcttcta
     3481 cc
//
