LOCUS       NM_001034876            1295 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus coiled-coil domain containing 24 (Ccdc24), mRNA.
ACCESSION   NM_001034876
VERSION     NM_001034876.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1295)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1295)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1295)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133118.1, BG088507.2 and CD774819.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133118.1, SRR5189685.167026.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-47                AK133118.1         2-48
            48-60               BG088507.2         1-13
            61-1268             AK133118.1         62-1269
            1269-1295           CD774819.1         1-27                c
FEATURES             Location/Qualifiers
     source          1..1295
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 53.69 cM"
     gene            1..1295
                     /gene="Ccdc24"
                     /gene_synonym="Gm1028"
                     /note="coiled-coil domain containing 24"
                     /db_xref="GeneID:381546"
                     /db_xref="MGI:MGI:2685874"
     exon            1..76
                     /gene="Ccdc24"
                     /gene_synonym="Gm1028"
                     /inference="alignment:Splign:2.1.0"
     exon            77..268
                     /gene="Ccdc24"
                     /gene_synonym="Gm1028"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..917
                     /gene="Ccdc24"
                     /gene_synonym="Gm1028"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 24"
                     /protein_id="NP_001030048.1"
                     /db_xref="CCDS:CCDS51281.1"
                     /db_xref="GeneID:381546"
                     /db_xref="MGI:MGI:2685874"
                     /translation="MLKALLQEIQSSQVSNSDPPSLLAPPPLLRDLIRQELRQLLQGL
                     RLKAISEGRDQTQMWAQYSPRVLRFALEDTRCDSTQQELPMRADEPRAGMNNTERVMV
                     TSPVSTCPRDLTVIKDQLNVSNIDQVVRHLRSLLEEECHMLQNEISDLQHCLEMEQMQ
                     ACQPSKDTQMPTLGEIKDQKAAMERELQVSLGPSCTAAKHRQKPLRSSIPSLRPFPCL
                     HGYMPTPPSERCPHPQGQTSTRRWGRQLRYSYRKETTSTSVSSAASQAPT"
     exon            269..382
                     /gene="Ccdc24"
                     /gene_synonym="Gm1028"
                     /inference="alignment:Splign:2.1.0"
     exon            383..508
                     /gene="Ccdc24"
                     /gene_synonym="Gm1028"
                     /inference="alignment:Splign:2.1.0"
     exon            509..563
                     /gene="Ccdc24"
                     /gene_synonym="Gm1028"
                     /inference="alignment:Splign:2.1.0"
     exon            564..633
                     /gene="Ccdc24"
                     /gene_synonym="Gm1028"
                     /inference="alignment:Splign:2.1.0"
     exon            634..712
                     /gene="Ccdc24"
                     /gene_synonym="Gm1028"
                     /inference="alignment:Splign:2.1.0"
     exon            713..1281
                     /gene="Ccdc24"
                     /gene_synonym="Gm1028"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1259..1264
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc24"
                     /gene_synonym="Gm1028"
                     /note="hexamer: ATTAAA"
     polyA_site      1281
                     /gene="Ccdc24"
                     /gene_synonym="Gm1028"
                     /note="major polyA site"
ORIGIN      
        1 actcccggag cggcctgaag tgaagaggat tctgggggag gcagcagtgg acctgagtct
       61 ggagttgcga gaggagtggc aaggtacccc agctctcctt acaggtggcg atgctaaagg
      121 cgctgctcca agagatccag tcttctcaag tttccaactc tgaccctccc tccctactgg
      181 caccaccccc cctcttgagg gacctcattc gccaagaact ccgacagtta ctccaaggcc
      241 tccgccttaa ggctatcagt gagggcaggg accagaccca gatgtgggcc cagtatagtc
      301 ccagggtcct tcgctttgcc ttagaggata ccaggtgtga ctcaacacaa caggaactcc
      361 cgatgagagc tgatgagccc agggctggaa tgaacaacac agagagggtg atggtaacct
      421 cacctgtcag cacctgtccc agggacctca ctgtcatcaa ggaccaactg aatgtgtcta
      481 atattgacca agttgtcaga cacctgagaa gccttctgga ggaagagtgt cacatgttgc
      541 agaacgagat ctctgacctg cagcactgtc tggaaatgga gcagatgcag gcttgccagc
      601 cctctaagga cacccaaatg cctaccctgg gagagattaa ggatcagaag gcggccatgg
      661 aacgggagct acaggtctct ctggggcctt cctgtaccgc tgccaagcac aggcagaagc
      721 ctttgaggtc atccattccc agccttagac ccttcccttg tctccatggc tacatgccta
      781 cacctccttc ggagcgctgc ccccaccctc aaggacagac aagcacccgc cgctggggac
      841 ggcaacttcg gtacagctat cgcaaagaga caacttccac atcagtttcc agtgcagcat
      901 cccaggcacc gacctgaagg gtcacaaaac aggcttctgc tgagactcgc ccatctgttg
      961 ttgcctccag ctgccacagc tccatttctg cttcattctc agatgcgctc acatgtttct
     1021 ccctccctcc cccagctgtg tgttggtctg gtcccagccc caccccttgt caggtcagtg
     1081 ctatctagaa ctgagtggca ggacacctgt tctaaccatc aaagcctttg gccccttctc
     1141 ctctgcacaa gcctccacag agccttggag gacagaggtt cccatcccag cttgactttc
     1201 gtcccctagg gacccagaca aagcacatca gcagctcaga gacaggaata gaaatttcat
     1261 taaaacctac ggactttaaa aaaaaaaaaa aaaaa
//
