LOCUS       NM_027801               3643 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus coiled-coil domain containing 191 (Ccdc191), mRNA.
ACCESSION   NM_027801 XM_915882 XM_990993
VERSION     NM_027801.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3643)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3643)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CT025520.10.
            
            On or before Jun 17, 2010 this sequence version replaced
            XM_915882.3, XM_990993.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence because no single transcript was available for the
            full length of the gene. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7974084.12044.1,
                                           SRR7345562.4832081.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-137               CT025520.10        84437-84573         c
            138-279             CT025520.10        76244-76385         c
            280-417             CT025520.10        68992-69129         c
            418-596             CT025520.10        67509-67687         c
            597-820             CT025520.10        65840-66063         c
            821-974             CT025520.10        58872-59025         c
            975-1165            CT025520.10        43091-43281         c
            1166-1415           CT025520.10        35312-35561         c
            1416-1876           CT025520.10        30511-30971         c
            1877-1968           CT025520.10        29745-29836         c
            1969-2051           CT025520.10        27724-27806         c
            2052-2153           CT025520.10        26947-27048         c
            2154-2297           CT025520.10        17514-17657         c
            2298-2450           CT025520.10        15107-15259         c
            2451-2596           CT025520.10        14312-14457         c
            2597-3643           CT025520.10        10161-11207         c
FEATURES             Location/Qualifiers
     source          1..3643
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 28.44 cM"
     gene            1..3643
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /note="coiled-coil domain containing 191"
                     /db_xref="GeneID:212153"
                     /db_xref="MGI:MGI:1922661"
     exon            1..137
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..2741
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 191"
                     /protein_id="NP_082077.1"
                     /db_xref="CCDS:CCDS57030.1"
                     /db_xref="GeneID:212153"
                     /db_xref="MGI:MGI:1922661"
                     /translation="MELSRWKRLSRKLNLKRVEKASEFAISNTCSTRNADLPGRFWRQ
                     AVDLATCEETEYHDDVYEEAQELVNDWLDNKLKQELASDGEGESTVLSSPPVPDAHDH
                     LKYDKFDDLCGYLEEEEESATVQKFIEHLLHKEVVASEMVEELGMEENQDKRQQKDPR
                     LTMEMRHKQVKENRLRREKQLESQRMADALKKAAFLEAQSLVQEEKRRKALLAKKEKE
                     DIQREMVKLRREILERRHTVEEAWKTEKKRQEEISQKNSEGKMMESTHIHLDEEKVAK
                     ERKRKLRETLIQTFKENQQCQKRYFSAWHKLILDHRIKLGKAGTLSDWKLQLKVLRAW
                     RDHTRSRKLERETKALENDLREENRKQQLATEFNRKHVLRYCFGEWQRWHGSEVIKRE
                     LALAKEQTRKKMDELLKAASLGKLSSKGSSGIGLVAEAVAVMDPAVGSGEVTILSPLW
                     ERPPVESSGCTLSHSPERTTKGNCQGPLPDVSGSTPGTEQCKAVAAETSEQPGSCERP
                     GTTRQEAEAACVRHFHRSHVYQQQLIEKQKKKLEQQQKTIQKLKENQRLAEARWAAKR
                     APAVTEGQNCLQSDPRGARDPQGTCQRLLKCEDSRTDCRKPLSASRRTLKQPTAPHPL
                     LKAMEERAIQRAERRQILAEKKKKQEEDKLAQLKAQEEERQKKDAEEKEAQLERKREE
                     RRLKKMKELEKQKRIKRIQELEAVAKGHYERVLLRKKGLEPWKRLRMQSKHNIEVAEK
                     YHSLALQRKCLLNWFQYSQETLAMKTAKADQFYSQLLYRRSIRSWLQYVSDLEKEVRR
                     LCTYLLQKKIFKAWLTTVRELKMDSQRKLKVATEHCDRKILMLTLEMWKAFVKLTKEE
                     RVKEERRDHLRRKVSEILPDFQMLVPP"
     exon            138..279
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            280..417
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            418..596
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            597..820
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            821..974
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1165
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1415
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1416..1876
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1968
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1969..2051
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2052..2153
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2154..2297
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2298..2450
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2451..2596
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2597..3643
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3006..3011
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3026
                     /gene="Ccdc191"
                     /gene_synonym="2610015P09Rik; 8430422M09Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcagttgtct ctgttgtggc cgaagtctag gcccgagagt gcaaaacgtg ctgctggcgc
       61 cccagggagg gtccgcctca aagaagaaga tggagctgag tcgctggaaa cggttatcaa
      121 ggaagctgaa tctcaagaga gtggagaaag cttcagaatt tgccatttcg aatacctgtt
      181 ctaccagaaa tgcagatttg cctggaaggt tttggcggca agcagtagat ctggcaacat
      241 gtgaggaaac agagtatcat gatgacgtct atgaagaagc tcaggaacta gtcaatgact
      301 ggctggacaa caaacttaaa caagaattag caagtgatgg agaaggggaa agcactgtgc
      361 tgagcagccc ccctgtgcca gacgcccatg accatttgaa gtatgacaag tttgatgatt
      421 tatgtggcta tttggaggaa gaggaggaaa gtgccactgt tcagaaattt atagagcatc
      481 tgctccataa agaagtggtg gcttctgaga tggtggaaga gcttggaatg gaggagaacc
      541 aagacaagag gcagcagaag gatcctcgtc ttaccatgga gatgagacat aagcaggtca
      601 aggaaaatcg cttaagacgc gagaaacaac tggagtccca gagaatggca gatgccctga
      661 aaaaagcagc cttcttggag gctcagagtc tagtgcagga agaaaagaga aggaaggctc
      721 tgctggccaa gaaagagaag gaggacattc agagagagat ggtaaagctg cggagggaga
      781 tacttgaaag aaggcacact gtggaagaag catggaaaac agaaaagaaa agacaagaag
      841 aaatttctca gaagaattca gagggaaaaa tgatggaaag tactcacata catctggatg
      901 aagaaaaagt tgcaaaagaa agaaaaagaa aactgaggga gacactaatc cagactttca
      961 aggaaaatca gcagtgtcaa aaacggtatt tctctgcctg gcacaagctg attctggatc
     1021 ataggattaa gctggggaaa gcggggactc tgtctgactg gaagcttcaa ctgaaggtcc
     1081 tgagagcctg gagagaccat acacgatccc ggaagttgga acgagagacc aaagccttgg
     1141 aaaatgacct tagggaagaa aacagaaaac aacagctggc tactgagttt aaccggaaac
     1201 acgttcttcg atactgcttt ggtgaatggc agcgttggca tggttcagaa gttatcaaga
     1261 gggagctggc tctcgcaaag gagcaaacta ggaagaaaat ggatgagctg ctgaaggcag
     1321 cctccctcgg gaaactcagt tctaaggggt catcaggtat cggtctcgtt gctgaggcag
     1381 tggctgtgat ggacccagca gtaggaagtg gagaggtcac tatcctgtcc cctttgtggg
     1441 aaaggccacc tgtggagagc agtggttgta cactcagcca ttccccagaa agaaccacca
     1501 agggtaattg tcagggtcct ctcccagatg tctctgggag cacacctggc acggagcagt
     1561 gcaaggctgt agcagctgag acctctgagc agcctggtag ctgtgaacga cctgggacca
     1621 caaggcagga ggcagaagct gcttgtgtga ggcatttcca ccgtagccat gtgtaccagc
     1681 aacagctgat tgagaagcaa aagaagaaac ttgagcagca gcagaaaacc attcagaagc
     1741 taaaggaaaa ccagcgcttg gccgaggccc ggtgggcagc taagcgagcc ccggcagtca
     1801 cagaaggaca gaactgcctt cagtcagacc ccagaggagc aagggacccg cagggcacct
     1861 gccagaggct tctgaagtgt gaagatagta gaactgattg cagaaaaccc ctttctgcat
     1921 ccagaaggac cctgaagcag ccaacagcac cccatccctt actgaaagcc atggaagaga
     1981 gagcaattca acgagctgaa cgtaggcaga tcttggcaga aaagaagaaa aaacaagaag
     2041 aagacaaatt ggctcagtta aaagcccaag aggaagaacg ccaaaagaag gatgcagaag
     2101 aaaaggaagc ccagctggag agaaaacgag aggaaaggag gctgaagaag atgaaagaac
     2161 tagagaaaca gaagagaatt aaaagaattc aagagttgga agcagtagcc aaaggtcatt
     2221 atgagagggt cttgctaagg aaaaaaggcc tggagccctg gaagagactg agaatgcaaa
     2281 gcaagcacaa cattgaggta gcagaaaagt atcactcttt ggctttacaa agaaaatgcc
     2341 tgctcaactg gttccagtat agccaggaaa ctctggctat gaagacagcc aaggctgatc
     2401 aattttactc ccaactgttg tataggagaa gcatccggag ctggctccag tatgtcagtg
     2461 atctagagaa agaagtcagg agactttgca cctacttact gcagaagaag attttcaagg
     2521 cctggcttac tactgtcagg gagctgaaga tggattcgca aagaaagctt aaggttgcca
     2581 cagaacactg tgacaggaag attctcatgc tcaccctgga gatgtggaag gcatttgtaa
     2641 aacttaccaa agaagaaaga gtgaaggaag aacgccgaga ccacctccgc cggaaggtct
     2701 ccgaaatcct tccagacttc cagatgctgg tgcctccgtg atggctgcat ccagtagcta
     2761 cccgcttgcc cgctgaggga agtctctggt gcctggacgt gtgcaggcta tctccaccca
     2821 cacaccagct gagcctggcc tactttctgg atgtgtcata gccctgggaa gtatcttggg
     2881 atttgttctt ccatcttgat atctcctgga ttgctaggca tctgttgtaa tgtctgtcac
     2941 agtgggtcat ccaaaggagc agtctagggc accactgttg agtgtatttt atatattctt
     3001 agtataataa acttgggaag gatgaatgtg cctgcctgga cttacggagg gggcgtcctt
     3061 attgcttgct gtgagctgca gtacgggtaa cactggagac aaacagaaag caatgaggac
     3121 agagagggca tgggtggcca gtgttctgtg atcagaacac gagtaacagg tgcccaccag
     3181 ggcccccgct ctcaatggca gagcatgatt aaaggtgctc tgcacagctc agcaggctgc
     3241 agcagcttat gctgatctca gagcagctag gacagccaag cacttggtac acagcaaggc
     3301 aagcgacagc tagtaacagc tccagcaggg accacccagc ccctcatctg aatgtctagc
     3361 catgttccca acccagcttc taagtaatcc atctgctttg tctgcttggc ctggcaactt
     3421 acactgaatt caaagaatgt tctaatattt aggattctgt aaagattgat caaatgttcc
     3481 cttctgtgaa cttttacaca gaatcatctg ctaggaattt tttcattata aaacttgtct
     3541 ttattgtgac aaattcaaat agtccacaaa tgcacacagt aaaatgcgaa acctcctcat
     3601 agcccagaac aactgaattg gttaaataaa actgtcgagc gaa
//
