LOCUS       NM_170757               6450 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus coiled-coil domain containing 186 (Ccdc186), mRNA.
ACCESSION   NM_170757 XM_006526851
VERSION     NM_170757.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6450)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6450)
  AUTHORS   Wang,G., Li,R., Yang,Y., Cai,L., Ding,S., Xu,T., Han,M. and Wu,X.
  TITLE     Disruption of the Golgi protein Otg1 gene causes defective hormone
            secretion and aberrant glucose homeostasis in mice
  JOURNAL   Cell Biosci 6, 41 (2016)
   PUBMED   27293546
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6450)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   4  (bases 1 to 6450)
  AUTHORS   Jensen,P., Magdaleno,S., Lehman,K.M., Rice,D.S., Lavallie,E.R.,
            Collins-Racie,L., McCoy,J.M. and Curran,T.
  TITLE     A neurogenomics approach to gene expression analysis in the
            developing brain
  JOURNAL   Brain Res Mol Brain Res 132 (2), 116-127 (2004)
   PUBMED   15582152
REFERENCE   5  (bases 1 to 6450)
  AUTHORS   Oduru,S., Campbell,J.L., Karri,S., Hendry,W.J., Khan,S.A. and
            Williams,S.C.
  TITLE     Gene discovery in the hamster: a comparative genomics approach for
            gene annotation by sequencing of hamster testis cDNAs
  JOURNAL   BMC Genomics 4 (1), 22 (2003)
   PUBMED   12783626
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158549.8.
            
            On or before Feb 8, 2019 this sequence version replaced
            XM_006526851.3, NM_170757.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17253014.2625513.1,
                                           SRR17253011.9861598.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-212               AC158549.8         159370-159581       c
            213-907             AC158549.8         150377-151071       c
            908-1034            AC158549.8         147621-147747       c
            1035-1163           AC158549.8         146575-146703       c
            1164-1376           AC158549.8         145360-145572       c
            1377-1496           AC158549.8         144348-144467       c
            1497-1601           AC158549.8         139267-139371       c
            1602-1700           AC158549.8         138549-138647       c
            1701-1787           AC158549.8         138295-138381       c
            1788-1930           AC158549.8         137446-137588       c
            1931-2186           AC158549.8         135949-136204       c
            2187-2376           AC158549.8         134826-135015       c
            2377-2457           AC158549.8         132472-132552       c
            2458-2668           AC158549.8         130678-130888       c
            2669-2888           AC158549.8         129323-129542       c
            2889-6450           AC158549.8         124867-128428       c
FEATURES             Location/Qualifiers
     source          1..6450
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 51.99 cM"
     gene            1..6450
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /note="coiled-coil domain containing 186"
                     /db_xref="GeneID:213993"
                     /db_xref="MGI:MGI:2445022"
     exon            1..212
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            213..907
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1034
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1163
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1164..1376
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1377..1496
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1497..1601
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1602..1700
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1701..1787
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1788..1930
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            1931..2186
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            2187..2376
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            2377..2457
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            2458..2668
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            2669..2888
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     exon            2889..6450
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6428..6433
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /note="hexamer: ATTAAA"
     polyA_site      6450
                     /gene="Ccdc186"
                     /gene_synonym="1810028B20Rik; A630007B06Rik; Otg1"
                     /note="major polyA site"
ORIGIN      
        1 ggcttaggcg tcgccgccat ctttgttgat gtgtcagctc cgcaggggtt ttgggggaaa
       61 acctccgctg agagcccggg atctgcagtg gtctccgcgc gtgacttcct cacccactcc
      121 gcgtcggcta cacgccgcca tgggttcgtc ggccctggag ccggagctcc atcggcctcg
      181 ctagggtgcg gcccggggct ggacgacgga cgatgtaaat gaagatcagg agcagatttg
      241 aagaaatgca aagtgaattg gtgccagtca gcatgtcaga gacagaacac atagcctcca
      301 tttcttctga tgcaactact gagaaaacat cggagttgag ggatgactcg tgcatctcag
      361 tttctggtga cgaaagcagc agattagaaa caggagctga actattgtca ttggactctg
      421 acagaatttt atgtcagact aatgaacact gtagtcagat cgaagtacag gagagccata
      481 ttccagactg tggcagtggt gagaattctt gtgctaacac agacacatgc ccagaagatt
      541 ctggacaaat agatgacttt cctggtggag actttacaga acaagtgtca aaaaccaagg
      601 agccagaaca gacagtaaca cagatactgg cagagttaaa gtcatctgca cccgcagaag
      661 ccgctaatcc aaagacggcc tcagcaagcc tctacgacac agactgcacc aggaaactca
      721 tttccgagat gaagactgtt tcagcctcag acgatttgtt gggagaaatc gaatctgagc
      781 tcttatctgc tgagtttgca gagggccacc aagtcccaaa tggactgaat aaaggagaac
      841 aggccttagc cctgtttgag aagtgtgtgc acagcaggta cttgcagcag gagctcactg
      901 ttaaacagtt aattaaagaa aataagaatc atcaggaact tatcttaaac atttgttcag
      961 aaaaagacag tttaagagaa gaactgagaa aaaggacaga aacagagaag cagcatatga
     1021 acacaataaa gcagttagaa ttaagaatag aggaactgaa taaagaaatt aaagcttcca
     1081 aagatcagct agtcgcacag gatgtcacag ctaaaaatgc aattcagcaa atccataaag
     1141 agatggccca gcggatggac caggccaata agaaatgtga agaggcccgt caggaaaagg
     1201 aggcaatggt aatgaagtat gtgagaggcg agaaggaggc tctagacctg cgaaaggaaa
     1261 aagaaaccct tgagaggaaa cttagagatg caagtaagga attggagaaa aacactaaca
     1321 aaattaagca gctgtctcag gagaaagggc ggctgcagca actctatgaa tcgaaggaag
     1381 gtgaaacaac tagactcatc agagaaatag agaaattaaa ggaggagatg aattctcaag
     1441 tcattaaagt aaagtgggcg caaaacaagt taaaagctga aatggactca cacaaggaaa
     1501 ccaaagataa actcaaagaa acaactacaa aactaaccca ggcaaaggag gaagctgagc
     1561 aaatccggca gaactgtcag gacatgataa agacctatca ggaatctgaa gaaattaagt
     1621 caaatgagct tgatgcaaag ctcagagtta caaaaggaga acttgaaaaa caaatgcaag
     1681 agaaatctga ccagctggag atgcatcatg ccaaaataaa ggagctagaa gatctaaaga
     1741 ggacatttaa ggagggcatg gatgagctac ggacattgag aacgaaggcg aaatgtctag
     1801 aagatgaacg cttaagaacg gaagatgagt tatcaaagta cagggaaatt atcaatcgac
     1861 agaaatctga aattcagaat ttactggaca aggtgaaaat cacagatcag ttacatgagc
     1921 agcttcaaag tggtaaacaa gaaattgaac atttgaaaga agaaatggaa agccttaatt
     1981 ctttgatcaa tgacctccag aaagacattg aaggcagcag gaaaagggag tctgagctcc
     2041 tgcttttcac agaaaagctc acgagtaaga acgcgcagct gcagtctgag tccagcgctc
     2101 tgcagtccca ggtggacaac ctgtcctgta ctgagagcca gctgcaaagc cagtgccagc
     2161 agatgggaca ggctaaccgt aatctggaga gcaagttgct caaagaggaa gagcttcgaa
     2221 aagaggaagt acagactctg caagctgagc tttctgctgc gcagaccgaa gtcaaagcct
     2281 tgagtaccca ggtggaagag ctgaaagatg agttagtgac gcagaggcgc aaacacgcct
     2341 ctaacgtcaa ggacctcagc aagcagcttc agcaagctcg gagaaagtta gagcagactg
     2401 agaatggaaa ccacgataaa gacattagca gtatgggaag tcgctcgagt tcatcagggt
     2461 cacttaatgc tcgaatcagt gctgaagacc gatctccaga gaataccagc tcctcggtgg
     2521 ctgtggacaa cttcccagaa gtggacaaag ccatgctgat tgagaggata gtgaggctac
     2581 agaaagccca tgcccggaag aatgagaaaa tagaattcat ggaggaccac atcaaacagc
     2641 tggttgaaga aataagaaaa aaaaccaaaa taattcagag ttacgtttta cgagaagaat
     2701 caggcacact ttcctcagaa gcatctgatt ttaacaaagt gcatttgagt agacgcggtg
     2761 gcatcatggc gtccttgtac acatcccatc ccgctgacag cgggctaaca ctggagctct
     2821 ctttggaaat caaccgaaaa ttacaggctg ttttggaaga tacattgcta aaaaatatta
     2881 ctttgaagga aaacctgcaa acacttggaa cagaaataga acgccttatt aaacaccagc
     2941 atgaactgga gcagaggacg aagaaagcct aacacaaagt tcttgcctag tagacagccg
     3001 agccacagag cagcaggtgc cactgtccag tgtcctcaaa cagtccctgc tttgtgtcaa
     3061 ctaatcaaaa attggttttg cttccctgtg tagaggtgcc cttttatgaa tgggtgtgtg
     3121 gtgtgtgtgc cgtgagcttt gtgagctcag caaagatcat ttctcatttc tctgtgctgc
     3181 agtcagccac cttgtcacta actcaatatt taatttgctt attgccctaa agtgctatag
     3241 tcattagtac aagggtttaa aaacaaacaa acaaacaaac aaggtaacca ccgtcctttc
     3301 cttagtgaca tcagcctgtg aaaagtcttc ctaaagagag gcgttcatca tgcaaccgct
     3361 caccattttc gcaacacaaa gagaaatcta gaggaattat aaaggttttc ggttctgatc
     3421 tgggcagtga tcacccctgt gggcctagct acttcgaagg ctaaagagga tctcttgagc
     3481 tcatgagttc aaagccagcc tggaaacatc ttaaaacccc atcacaatca gccgccgtca
     3541 cggaatagcc ttgggttgtg gtgtaaggat gtgtgtgcgt acttaaatca gttctgagtt
     3601 tactgacaaa tagacaggaa agctggctgt agggaattag ccctggctgg gcactgtttg
     3661 tcaggtctcc ttatatgaca taggtatatt tttcacattt gagttactaa ttaaaatttt
     3721 aaaatcttta gtgatgtaaa ctatgatttt aaactctgaa cttaaaactt tcctgtggat
     3781 ttgttatatt ttaatatgtg aaatggatcc agtcattgga acagatgtgt gaagctctgg
     3841 ggctgaggtg ctttctgcca tgccttggtt ttactgacat tgtgtacagg ggaatgtaaa
     3901 gggcttgggc ggaggctcct gtgtgcccat cacatcagga gatgctcagt ttcctcaagt
     3961 gctgtttctg tatgatcttt aacacagtta tgtcttcagc cgaagggact ttggagctga
     4021 attgtgtatc ttgttggatg tttacagtgt ttaagatgta cgtttaaatg ttgccaattg
     4081 tagtatcagc acttctgtca ttgaaggttt tctcagttgg tagcatctta cctcccagaa
     4141 cctaacacac cgcatcctgg gaggctgcta cgtttgggtt tgggtttttg gggttggttt
     4201 ttattttttg ttttttgggg ggttttttgg tttgtctttt cctcttaaag aacttgggct
     4261 ttaggataca tagctttaaa gaatggtatg agctctagcc tggcatggcc gctcatgccc
     4321 atcatcccag ccctcaggag gtgacggcag gagagtatta cagacgagcc ttgagcacag
     4381 tgaaatgcag atgccttgga agcctggact atcatagaat tttgcgggct ctaagattac
     4441 agtcatgacg tcagtgccct tttactgtgt tttaacattt cctcaaatca acatcgatta
     4501 taaatgtaat actagatgtc aatataatgt ctttgtgaat attatgttat tactcaaaaa
     4561 agtatctctt agcttcagtg tgaaatgcat tcaaagttgt tttattttta agatagttgt
     4621 aaaaagtatt agtcatctgt cttgctcttt ttattattaa taatttatta gaataaaaat
     4681 taagagggta agtgcaataa actctgcatt atttcccacg tattcctagg cacacttccc
     4741 tagccctggg aagggctcca gagtgtaggc agcctagcta caccccctgt ctcctcggct
     4801 gatgctgagt catgagctag agcattaggg ctttttaatt ccaagacacg aaaatgcata
     4861 gtggagacca accagtgatc atgtccacag tattctgtac ctgggcactc gtaacatata
     4921 tgcacatttg gtatagaatg ggacaaactg tgttagcact tgtgccgcca tggacttgga
     4981 gaacttaata atgtaataat ttaaaagtat aattactaaa agccatgcgt tgattataca
     5041 gactgtcctc ccatatctat gaagcttaaa aagctgaaaa agttttattt tctttttcat
     5101 taggcatctc ctatgtcctt tcatatatgg tcaagactga gcaaaagcat gtgtaagaaa
     5161 tgcatttatg tccaagagaa cctccactga cttagggcgc gctcctgggg tagatttgtt
     5221 tctgaggttc ttctcctcat agaatacgtg gaggagagac cctgagacga cagtgtgtat
     5281 tgatcattgt tagttacaaa tgtaaatgac tatttattta gtaatatttt ggtatccttg
     5341 ggcaagaagt tggtgtgcgt gcatgtgtgg gtccacacac ttccctggct ttcatctgaa
     5401 agtgagtgct tgggactcct ttttttccat cccacttgag atttttgagt ctgttcattt
     5461 tcaaggcttg aacatggtgc gtttggacac aatgaacagt tggtggtggt ttggtttggt
     5521 ttctccataa ccatttaaag tgactcactc aatcaggcta cacaggtcat ttattcatta
     5581 agaaatacat ttgcctaata aacactaata aaccggcacg ctacgggtgt catggttatc
     5641 actctccagt cccttggcat ctgtgctctc atgacagcag caggacgggt cttcaggcct
     5701 tactctcagg ctgccctttg tcactgggct aagaagagtg ctgttctgct tgcacaggta
     5761 gatgagccaa gcgcctcagc ctgagctcgg gcctggggaa agtgctgttc ccatggtgct
     5821 ctgcccaaag actgtaagaa gacactagac ttttagcatt tcgtaaccgc ttgactggtg
     5881 cctgttccgt gctcctgaaa tgagtccaat ccagtcgggc agccttctga agtcccttgt
     5941 acaggctgtt ggttattttc taaatatttt tacaagaaaa tttagtctta aatttggaag
     6001 aagaaacccc ccccttgaaa ctatcaatac tgtaaatgtg acacatgttg ccctggtaag
     6061 gatatatata aaatgacatt catgctttgg gactattgac tctactgatc tctttttcaa
     6121 gaattttttt cagttcattt tcatactgat attgttaaca cttaacacca attggtggca
     6181 ctagtgactg aaaattgtta aaggtgaaca agagaaataa ttgaaaaaaa agcaaactaa
     6241 acaagaactt agttgcatat tgaaatgtat gcatatggct atcattcatg cctgctgctc
     6301 tcttcccttc ccgagtgcag ggctgtctgc gttgtgtagg gaaccctggg ttgattacac
     6361 tgtgcattct gtaaatactc tgtataaagt gatgctcttc aggggagtct gtgtacattc
     6421 tgtacttatt aaataagcag tgcctgttta
//
