LOCUS       NM_029372               1122 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus coiled-coil domain containing 172 (Ccdc172),
            transcript variant 2, mRNA.
ACCESSION   NM_029372 XM_129272
VERSION     NM_029372.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1122)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1122)
  AUTHORS   Yamaguchi,A., Kaneko,T., Inai,T. and Iida,H.
  TITLE     Molecular cloning and subcellular localization of Tektin2-binding
            protein 1 (Ccdc 172) in rat spermatozoa
  JOURNAL   J Histochem Cytochem 62 (4), 286-297 (2014)
   PUBMED   24394471
  REMARK    GeneRIF: TEKT2BP1 was predominantly expressed in rat testis and
            that its expression was increased after 3 weeks of postnatal
            development; a isolated and identified TEKT2BP1 (Ccdc172) as a
            partner of TEKT2 by yeast two-hybrid screening
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158904.4.
            
            On Sep 10, 2019 this sequence version replaced NM_029372.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC049707.1, SRR5189685.60027.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-82                AC158904.4         39431-39512
            83-207              AC158904.4         39758-39882
            208-293             AC158904.4         40063-40148
            294-410             AC158904.4         53295-53411
            411-576             AC158904.4         54719-54884
            577-678             AC158904.4         64008-64109
            679-781             AC158904.4         64709-64811
            782-869             AC158904.4         78875-78962
            870-1122            AC158904.4         80299-80551
FEATURES             Location/Qualifiers
     source          1..1122
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 54.35 cM"
     gene            1..1122
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /note="coiled-coil domain containing 172"
                     /db_xref="GeneID:75645"
                     /db_xref="MGI:MGI:1922895"
     exon            1..82
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            83..207
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..932
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /note="isoform 1 is encoded by transcript variant 2;
                     UPF0628 protein C10orf96 homolog; coiled-coil
                     domain-containing protein 172; TEKT2-binding protein 2"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 172
                     isoform 1"
                     /protein_id="NP_083648.1"
                     /db_xref="CCDS:CCDS38029.1"
                     /db_xref="GeneID:75645"
                     /db_xref="MGI:MGI:1922895"
                     /translation="MSLESLFQHIIFSEHQAEESRRVMREVRSEITRCRGKIKKATED
                     LSEEKIKLESKVQQLSEKSFLLELLKTHENALERQLSEIISERDTLLQACEAIKNKTT
                     EEEERFIKEITDFNDNYEITKKRDTLMKENIEMEMADLDSQADVLRREMKSVERNRGQ
                     LWELQKLKNELLQELFTLQKKLKVLKDEETEAICITKQLEAEKTKVRDKPQHDPECVR
                     LKRELDLYKAEDMESVYRALQAEVDLLELALAPKDPQDSNSLSHEPPHT"
     exon            208..293
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            294..410
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            411..576
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            577..678
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            679..781
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            782..869
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            870..1122
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1028..1033
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /note="hexamer: AATACA"
     polyA_site      1051
                     /gene="Ccdc172"
                     /gene_synonym="1700011F14Rik"
                     /note="major polyA site"
ORIGIN      
        1 gacttctcgc gagatcagtg gaggccgcct gcgctggaca cacgtgaggg gacgagggga
       61 cgtcgccagc ccctgaccac aggatcctca gactccctta tcaaatatta agggcgagcc
      121 ggccggagat gagtctggag tccttgtttc agcacatcat cttcagtgag catcaggcgg
      181 aggagagccg cagagtgatg cgggaagtaa ggtcggagat taccagatgt cgtgggaaaa
      241 ttaagaaagc aacagaggac ctgagtgaag agaaaatcaa gttggaatcc aaggttcagc
      301 agttgtctga gaaatctttc ctcttagagc ttctgaaaac ccatgaaaac gcattagaga
      361 gacagctcag tgagattatc agcgagcggg acacactgct ccaagcctgc gaggctataa
      421 agaataaaac cacagaggaa gaggaaagat ttattaagga aattacagac ttcaatgaca
      481 attatgaaat aaccaagaaa agagatactt tgatgaaaga aaatatcgag atggaaatgg
      541 ctgacttaga cagccaggca gatgttttga gaagggaaat gaagtcggtg gaacgtaacc
      601 gtggacagtt atgggaactc caaaaactaa aaaatgaact gttacaagaa ttatttactc
      661 tccagaaaaa gcttaaagtt cttaaagatg aagagactga agccatttgt atcaccaaac
      721 agctagaggc agaaaaaacc aaagtaagag ataagcctca acatgatccc gagtgcgtgc
      781 ggcttaaaag ggagttagat ctgtataaag cagaagacat ggaaagtgtc tacagagctc
      841 tccaagcaga agtagacctc ctggagttgg cactggcacc aaaggatccc caggacagta
      901 actccttgag tcatgagcca ccccacactt gagcatcaga gaaccacaca tgagtggagc
      961 ctgtagagct gatctctacg tgaacatgag gatcaggcag tgcagaggag tgatgactct
     1021 attgcataat acattttatc ttgttaccta agaggtcctt gtacagtttc taaggggaga
     1081 gaaagaagaa gatactaaac tccagattta agttggtctg tc
//
