LOCUS       NM_146059               2301 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus coiled-coil domain containing 166 (Ccdc166),
            transcript variant 1, mRNA.
ACCESSION   NM_146059 XR_035296 XR_035335
VERSION     NM_146059.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2301)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2301)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC116487.14.
            
            On or before Jul 1, 2009 this sequence version replaced
            XR_035296.1, XR_035335.1, NM_146059.1.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript but encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.4518193.1, CJ112194.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-485               AC116487.14        114694-115178
            486-2301            AC116487.14        115292-117107
FEATURES             Location/Qualifiers
     source          1..2301
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 35.18 cM"
     gene            1..2301
                     /gene="Ccdc166"
                     /gene_synonym="2410075B13Rik"
                     /note="coiled-coil domain containing 166"
                     /db_xref="GeneID:223648"
                     /db_xref="MGI:MGI:1925902"
     exon            1..485
                     /gene="Ccdc166"
                     /gene_synonym="2410075B13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..1406
                     /gene="Ccdc166"
                     /gene_synonym="2410075B13Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 166
                     isoform 1"
                     /protein_id="NP_666171.2"
                     /db_xref="CCDS:CCDS59621.1"
                     /db_xref="GeneID:223648"
                     /db_xref="MGI:MGI:1925902"
                     /translation="MAPKKKRGQNAGRKQETTEQPLSERAQYLQREYALLSESLVACE
                     QRIDEVLQDNEFLNREAQRLREENRLYVGYVSAHALRCANAVVRVEDQNRMDLAQIRW
                     QRAELASFYHGREDGVRAQLQEMKKRAENMTQRVQELQPYKELQLEQLARIRTLEREL
                     LHMRVEHTQLLHGVKRRFLDEKTAFEREARLQVQSLTRRSEREAARSLISHAQALKAD
                     NGYLRQELMRLLQRTQLLQDMRQQLLEQREQLRREHVDLKNLEQMHGWLQRGPGGPPL
                     WQPPQSLQPSLRIGSTSHVLKAQATPQSVPTSRGQSMDLSHRPSKTPSILSSESLPGL
                     SQKAGSVIALRSPSHPGSRVSSLTPSRKDSRVSSATPSRKGSRVPSMTSGTLRSREGS
                     RISPQPSLREVSPEIDTPAKSSSKLPTALLEDQAPLSPQLEEAENAEDDTETVLEQA"
     exon            486..2301
                     /gene="Ccdc166"
                     /gene_synonym="2410075B13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1485..1490
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc166"
                     /gene_synonym="2410075B13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1502
                     /gene="Ccdc166"
                     /gene_synonym="2410075B13Rik"
                     /note="major polyA site"
     regulatory      2277..2282
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc166"
                     /gene_synonym="2410075B13Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2301
                     /gene="Ccdc166"
                     /gene_synonym="2410075B13Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggggagcggg tggagcacag cgctctcatg agtccagttg gcttgggcct caagccatgg
       61 cgcccaagaa gaagcgcgga caaaacgcgg ggcgcaagca ggaaactaca gagcaaccgc
      121 tctcggagcg cgcgcagtac ctacagcgcg agtacgcgtt gctctcagaa agcctggtgg
      181 cctgtgagca gcggatcgac gaggtgctgc aggacaacga gttcctgaac agagaggcgc
      241 agcgcctgcg cgaagagaac cggctttatg tcggttacgt gagcgcgcac gctctgcgct
      301 gcgccaacgc cgtcgtgcgc gtcgaagacc agaaccgcat ggatctggcg cagatccggt
      361 ggcagcgagc ggagctagcg tccttctacc acggccgtga ggacggggtg cgcgctcagc
      421 tgcaggaaat gaagaagcgc gcggaaaaca tgacgcagcg ggtgcaggag ctccagccct
      481 acaaggagct gcagctggag cagctggcgc gaatccggac cctggagcgc gagctgctgc
      541 acatgcgcgt ggagcacacg cagctcctcc acggggtgaa gcgacgcttc ctagatgaga
      601 agacggcttt cgagcgggag gcgcggctgc aagtgcagtc cctgacgcgc cgctccgagc
      661 gggaggccgc acgttccctc atttcccacg cacaggccct caaggcggac aacgggtatc
      721 tccgacaaga actcatgaga cttctccaga ggacccagtt actgcaggac atgcgacagc
      781 agctgctaga gcagcgggag cagctgcgcc gggagcatgt ggacttgaag aacctggagc
      841 aaatgcacgg ctggttgcaa aggggccccg gggggccacc gctctggcag ccaccccaaa
      901 gcctccaacc cagcttgcgc atcgggtcaa ccagtcacgt tttaaaagcc caggctacgc
      961 cccagtcagt tccaacctcc cggggccaat ccatggatct gtcacaccga ccctccaaga
     1021 ctccatctat attgtccagt gagtctcttc cgggcctatc tcagaaggct gggtcagtga
     1081 ttgctctccg gagtccatca catccaggat ctcgagtctc atctctgact ccatcacgca
     1141 aggactcgcg tgtctcatcc gcgaccccgt cacgcaaggg ctccagggtt ccatccatga
     1201 cctctggtac cttgcggtcg cgcgagggct ctcggatctc tccacagccc tccttgcgtg
     1261 aggtctctcc agaaattgac acacctgcaa agtccagttc caagcttccc acagccctgt
     1321 tggaagatca ggcccctctc agcccacagt tggaggaggc agaaaacgct gaagacgaca
     1381 cagaaactgt cttggagcaa gcctgaaccc acacgaggag gcaggccagt agggcatagg
     1441 gtggaggaca aaccttggaa gatttcttgg tgcatagata tgttaataaa agtgttaaat
     1501 aagctctgtg acgctctgac acttgcctgg gtcgatgccc ttgtatttca agtgagcaga
     1561 ggcctgctat tcgagctaca gcagagctgg ttgtatcctt ggctgctgga attcgatgtt
     1621 cttccaccaa cagccagcaa ggcaggcagg cttagggaaa gttgggtagt gtaatttcag
     1681 cagcagaggg cagattctgt tctcagcaca gggagaagtt actgggcttt tccaatgctt
     1741 tatataatac gcacacacac atatgtatgt aggtatgtat atgtatatat gtatatacat
     1801 tccaatttag ggaacactgc aagaattatt aggaattccc attgccaccc atctagatga
     1861 acagggatgc atgttatata tttggtactt tcagccatcc gggattctgt tggagacagt
     1921 tatgcccctt aattttaaat atatccctgt gtttactgaa taggactttg acctgttttc
     1981 ttccggtgct gggtgttgaa cccagggcta cctcctgagc tacagcccaa gccctgtccc
     2041 aactttcttc aagacatgat taaaattagg aaatgcacct tggagaaaat actgtaaact
     2101 aaatcatact ggccaaattg tccctgtggt gtctgtagct agctatggat cttacctggg
     2161 tcacatctta cattccattg tgctggtctg tcctttcctt tatagaaagg gtctgtatag
     2221 gtcaggctgg ccttgaatcc aagagatcct cctgcctctg tctcttcagt gctgagatta
     2281 aaggcatcca ccaccacctc a
//
