LOCUS       NM_001164620            5017 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus coiled-coil domain containing 157 (Ccdc157),
            transcript variant 1, mRNA.
ACCESSION   NM_001164620
VERSION     NM_001164620.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5017)
  AUTHORS   Zheng,H., Gong,C., Li,J., Hou,J., Gong,X., Zhu,X., Deng,H., Wu,H.,
            Zhang,F., Shi,Q., Zhou,J., Shi,B., Yang,X. and Xi,Y.
  TITLE     CCDC157 is essential for sperm differentiation and shows
            oligoasthenoteratozoospermia-related mutations in men
  JOURNAL   J Cell Mol Med 28 (7), e18215 (2024)
   PUBMED   38509755
  REMARK    GeneRIF: CCDC157 is essential for sperm differentiation and shows
            oligoasthenoteratozoospermia-related mutations in men.
REFERENCE   2  (bases 1 to 5017)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: 4930562D19Rik is most abundantly expressed in tissues rich
            in highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133165.1 and AL807825.5.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133165.1, SRR9219382.202941.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2561              AK133165.1         2-2562
            2562-5017           AL807825.5         12894-15349         c
FEATURES             Location/Qualifiers
     source          1..5017
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 2.9 cM"
     gene            1..5017
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /note="coiled-coil domain containing 157"
                     /db_xref="GeneID:216516"
                     /db_xref="MGI:MGI:3041210"
     exon            1..135
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /inference="alignment:Splign:2.1.0"
     exon            136..283
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /inference="alignment:Splign:2.1.0"
     exon            284..542
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /inference="alignment:Splign:2.1.0"
     CDS             295..2451
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /note="isoform 1 is encoded by transcript variant 1;
                     coiled-coil domain-containing protein 157"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 157
                     isoform 1"
                     /protein_id="NP_001158092.1"
                     /db_xref="CCDS:CCDS48743.1"
                     /db_xref="GeneID:216516"
                     /db_xref="MGI:MGI:3041210"
                     /translation="MAHLLGSQACMDSLRKDLTDLQGTIVDVFSRAGPVRFPSWKFPD
                     RVACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCASYLENLSVEQ
                     MMPPARAAGPCMSVGLTVRRFWSNLLRLGLLYQQAVPQKRANQGEISITKPTAKGEPA
                     RSPECMTAKFIKPPSPVPGLPLICQGLQSIPVRVSLRSPGGTSEKTKSVYSQTVETAL
                     VPCDACTSVQGSLWEVGKVVISLCQSQNLPSSLGQFQKLVKDSLGLKPLPAATVGHWA
                     AEQSKDLTRLNKHVGALTQLVGPLRAQLEDAEGQKDGLRKQVSKLEQALQQEQGQRQR
                     QTEEAERTLAKCEHDRHQLLTETCDLKTKVAVLEGDLKQQQKSIQAMEAKAQQLEEEG
                     ERRAAAERQVQQLEEQVQLLAGRLDGASQQIRWASTELDKEKARVDSMVRHQESLQAK
                     QRTLLQQLDCLDQEREELRGSLDEAEAQRSELEEQLQSLQSDREQEQCQLQAQQELLQ
                     SLQQEKQDLEQVTTDLQLTISELRQQLEELKERERLLVAFPDLHQPEEAQIQSSSNVT
                     QDMERQVQANAIRIQVLQEENKRLQSMLTKIREVAQQGGLKMVPQGQLWSPPYKGIQG
                     ATPPAQAQSAFSGLTGRRQSPGSRTSSTGRTHPGGLRTSPSRQPGGLPSKFSLGDGSH
                     SASCTQNPIRALARLRRKLSPNRQAGSTYQPQERPT"
     exon            543..714
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /inference="alignment:Splign:2.1.0"
     exon            715..1360
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1438
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /inference="alignment:Splign:2.1.0"
     exon            1439..1629
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1806
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /inference="alignment:Splign:2.1.0"
     exon            1807..1975
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /inference="alignment:Splign:2.1.0"
     exon            1976..2115
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /inference="alignment:Splign:2.1.0"
     exon            2116..2204
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /inference="alignment:Splign:2.1.0"
     exon            2205..5017
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4997..5002
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /note="hexamer: ATTAAA"
     polyA_site      5017
                     /gene="Ccdc157"
                     /gene_synonym="4930562D19Rik; mKIAA1656"
                     /note="major polyA site"
ORIGIN      
        1 gcggtacgcc gttgccaagg cagcggcctg ggctcccaac ttagagttgc gaggcattct
       61 cggagcctca gacgctctgg aggaagttct gtgagccaga cagacacaga gctgaggctg
      121 cgacgccgga gacagggatg ggagggccgc ttgcggccgg ccctgaatca ggaagccagg
      181 agccagaaag ccaggcacct gcatgaatcc caggcctccc agcctagtcc aaaagctgga
      241 catagtcagc cactccagct tcatgggcaa acatctgtga gaggagctgt ggggatggca
      301 cacctgctag gcagccaggc ttgtatggac agcctgcgca aggacctcac cgacctgcag
      361 ggcaccattg tggatgtgtt ctctcgtgct gggcctgtgc gcttcccctc ctggaagttc
      421 cctgatcgtg tggcctgcga ccttgacatg gtggcccttc tggagcacta tgaccatgtg
      481 ccaggtgacc ctgagttcac acagttgtcc catgccgtgc tgctggagct ggtcattgac
      541 aggctcctgc tgctgcttca gagttgtgcc agctacttgg aaaacctcag tgtggagcag
      601 atgatgcctc ctgcccgggc tgcagggcca tgcatgtccg tgggacttac agtacggcgc
      661 ttctggagca acctgcttag gctgggcctg ctctaccagc aggcagtccc ccagaaaaga
      721 gcaaaccaag gggagatttc tatcaccaag cccacagcta agggtgaacc agccaggagc
      781 ccggaatgta tgactgccaa gttcatcaag cccccttccc cggtgccagg cttgcctttg
      841 atctgccaag ggttgcagag catccctgtc agagtctccc tgcggagccc aggtggaacc
      901 tctgagaaaa ctaagagcgt ctactcccag accgtcgaga cagccttggt gccctgtgat
      961 gcttgcacca gtgtccaggg cagcttgtgg gaggtgggca aggttgttat cagcctgtgt
     1021 cagagccaaa acttgccttc atccttgggc cagttccaga agttggtgaa ggacagcctg
     1081 gggcttaaac cactgccagc tgccaccgtg ggccactggg cagcagagca gagcaaagac
     1141 ctgactcgtc tcaataaaca tgtgggggcc ctcacccagc ttgttgggcc cctcagggct
     1201 cagctggaag acgctgaggg gcagaaggat gggctgagga agcaggtgag caagctggag
     1261 caggccctgc agcaggagca agggcagcgg cagcggcaga cagaggaggc tgagcggacc
     1321 ctggccaagt gcgagcatga caggcatcag ctgctcacag aaacatgtga cctaaagaca
     1381 aaggtggccg ttttggaggg agacctgaag cagcagcaga agtccataca ggccatggag
     1441 gccaaggctc agcagctgga ggaggaaggg gagcgtaggg cagcagctga gaggcaggtg
     1501 cagcagctgg aggagcaagt gcagctgctg gcggggcggc tggacggggc tagccagcag
     1561 atccgctggg ccagcacgga gctggacaag gagaaggccc gcgtcgacag catggtccgt
     1621 catcaggagt ccctgcaggc caagcagagg actttgctac agcagctgga ctgtctggac
     1681 caggagcggg aagagctgcg gggaagtctg gatgaggctg aggcccagcg gtctgagttg
     1741 gaggagcagc tgcagagcct ccagagcgat agggagcagg aacagtgcca gctacaggcc
     1801 cagcaggaac tgctgcagag cctgcagcag gagaaacagg acctggaaca ggtgactaca
     1861 gacctgcagc tgaccatctc tgagctacgg cagcagctgg aggagctgaa ggaacgggag
     1921 cggctgctgg tggccttccc agacctgcac cagccagagg aggcccagat ccaaagctct
     1981 agcaatgtca cgcaggacat ggagaggcaa gtgcaagcca atgctatccg tatccaggtc
     2041 ctacaggagg agaacaagcg gctccagtcg atgctgacca aaatccgaga ggtggcccag
     2101 cagggaggcc tcaagatggt cccgcagggc cagctctggt cccctcccta caagggcatc
     2161 cagggagcaa cccctccagc ccaggcccag agtgcattct cagggttgac aggcagacgg
     2221 cagtctcctg gcagcaggac aagcagcaca ggcaggaccc atcctggcgg gctccgtaca
     2281 tccccgtctc ggcagcccgg cggcttgccc agcaagttct ctttggggga tggaagtcat
     2341 tcagcatcct gcacccagaa tcccataagg gccttggcca ggctgaggag aaagctttca
     2401 ccgaaccgtc aggctggttc tacataccag ccccaggagc ggcccacgta acccgcagca
     2461 ggggtagggc tggagggcag gtggctagca gtcccccatg gaataaaagc cccagccatc
     2521 tgcccactgc gatcttggcc tcagtgtggc tgagctggag gaacagacct ccccttcttg
     2581 ttgggtaagg tcctccgtga tcccaccatg ttggttgctg gccaatggta gcctcgcgtg
     2641 agttgggagc ttcctgtctg tgtctggcag gcgctgtggg aggaccacat tgagaggcag
     2701 catctgagcc aagtgaagcc cagcctttgt gtcccataga aacggctgag gggtaactcc
     2761 acatccattg gccagcactc ggggtagggc ttggggtatg aggacacatc tgaaacaacg
     2821 agctaggcta ggagctggac ctctggttca gcaaggcagg cagagagcag tgttgccttt
     2881 gccttccacc tgggctctac atctgataca ggaccaaagg gcaccaggca gctcaccggg
     2941 agcttgttcc tctaggaaca actgggaagt ccctcttaag tcctagaagt cagagcccca
     3001 ccaaatcatt ggaggacagt ccaggccttt ggatacctta gccagccgtg gggctcaccc
     3061 agttacagga tgacacaaga tggagcaagg atgctaccag ccacaccatg cacacagtgg
     3121 tcattcttct aagcaagcca ctagcctacc ttgagttgtg ttgtttgtga tggacaggct
     3181 ctaaattttt actgaggatt tctcagggca cactcaccta gtgtgggtgg cattatttat
     3241 tgtgtaggtt tgagtgccta agtcaatagt gaaggtttcc caacctgctt cttttttgga
     3301 gaggggtgta tttcaagaca gcacttctct gtgcagccct ggctgtccta gagctctgta
     3361 gaccaggctg gccttgaact cacagagatc tacctgcctc tgcctcccaa gtgctgggat
     3421 taaaggtgtg cgccactact gctggcccaa ctctgcttct taacagccca agggttctgg
     3481 gggagactgg aggctctgag ccactctacc tggggagagc cagctttggg cacagctccc
     3541 cgagagaggc cctgtgactg ctgaagatcc catgcctctg ctgagtcagc atctacttac
     3601 tcactctcgc ttgtgccagg cagtaggcca gatccttctc atttaggtga cacataccct
     3661 agggaggctg aaacaggaag actgagagct tgaggctagc ctatgccata tagcaaggac
     3721 ctaactcaga caacacatgg acaggcataa aacgatagga aacaatcaaa aaagtccaga
     3781 agtccatcta tttgatcagg ccctttgctc agggtgctca gagggggaaa ctaaggtatc
     3841 actcaggatg gctcctttag atggctctgg gcaagagtcc tcttacaagc tcctggctgt
     3901 gacagagctt taggcttagg cttaggctgt ggggttggag ccttgctgct tcaaggagcc
     3961 ttccttgcct ggcttcttat tggtaccacc catcttcaag aaggcagcag aggtgggcat
     4021 ggtagcactt taatcctggc actcaggagg cagaagcagg agtctctctt tgagtttgag
     4081 gctaggctgg tatacagaga aagctccagg acagccagag ccacttacaa accctgtctc
     4141 aaaaagaaaa agagaaagaa atggagggtg tgcagcagac aatgtgtgtc ctgtatggga
     4201 tgccccaagg tcctctactt cctcctgctt tccgtgggct tgtgtgttgg tcagatgctt
     4261 tcctcatttt tattgttagt gtttagtgtt gggaactgaa ttcaggccct tgtgcattct
     4321 aggcaagtgc tctaccagct ccccatgccc cagtccttgc ctctctcatc tgaaggtcac
     4381 tttacataac ctgttcacag gggctaaaat gtcttagagt caatatttta aagattatgc
     4441 aaggtatgtt tgtgcagccc aggagtgcaa ggccttgagg aatttaagaa ttctacctgt
     4501 tcccagcaag agaaaccaag gtgactggta ttttgtttgt ttttcttttt gagagtagcc
     4561 caggctgact tcaaactccc tgtgcagcca aggatgatca ggagttcatg atcctctggt
     4621 ttcccttccc agaggacaaa gaacaagggg attgcaggga ctgcccagca gccttgaact
     4681 ttttgttttg tgatgttata ttgagacagg gtctctctgt atagtgctgg ctgtcccgga
     4741 actcgctatg tagaccaggt tggccttgaa ctcacagagg tctgcctgct tctgccttac
     4801 cagtgctagg attaaagggg tgcactgcta tgcccagctg gtcttaaact atgaatcctc
     4861 ctgtctccac ctccatgttt ctgggattat tggcatatgt caccacatac ccatcttttc
     4921 cttaatatct taaagcatca cacagattta tgtcttaaca gatttatgtt aaaatagatt
     4981 ccatgtttat tttactatta aaacttccct acccaaa
//
