LOCUS       NM_001079929            2407 bp    mRNA    linear   ROD 07-OCT-2024
DEFINITION  Mus musculus coiled-coil domain containing 154 (Ccdc154), mRNA.
ACCESSION   NM_001079929 XM_001479029 XM_139904
VERSION     NM_001079929.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2407)
  AUTHORS   Xu,K., Bai,X., Chen,S., Xie,L., Qiu,Y., Li,H. and Sun,Y.
  TITLE     CCDC154 Mutant Caused Abnormal Remodeling of the Otic Capsule and
            Hearing Loss in Mice
  JOURNAL   Front Cell Dev Biol 9, 637011 (2021)
   PUBMED   33614666
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2407)
  AUTHORS   Liao,W., Zhao,R., Lu,L., Zhang,R., Zou,J., Xu,T., Wu,C., Tang,J.,
            Deng,Y. and Lu,X.
  TITLE     Overexpression of a novel osteopetrosis-related gene CCDC154
            suppresses cell proliferation by inducing G2/M arrest
  JOURNAL   Cell Cycle 11 (17), 3270-3279 (2012)
   PUBMED   22895184
REFERENCE   3  (bases 1 to 2407)
  AUTHORS   Lu,X., Rios,H.F., Jiang,B., Xing,L., Kadlcek,R., Greenfield,E.M.,
            Luo,G. and Feng,J.Q.
  TITLE     A new osteopetrosis mutant mouse strain (ntl) with odontoma-like
            proliferations and lack of tooth roots
  JOURNAL   Eur J Oral Sci 117 (6), 625-635 (2009)
   PUBMED   20121924
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133084.1 and JN935900.1.
            
            On Aug 23, 2012 this sequence version replaced NM_001079929.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-388               AK133084.1         2-389
            389-1055            JN935900.1         8-674
            1056-1272           AK133084.1         1153-1369
            1273-1919           JN935900.1         892-1538
            1920-2407           AK133084.1         2037-2524
FEATURES             Location/Qualifiers
     source          1..2407
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.53 cM"
     gene            1..2407
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /note="coiled-coil domain containing 154"
                     /db_xref="GeneID:207209"
                     /db_xref="MGI:MGI:2685163"
     exon            1..388
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     CDS             382..2376
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /note="Grailexp predicted; golgin-160-like protein"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 154"
                     /protein_id="NP_001073398.2"
                     /db_xref="CCDS:CCDS50032.2"
                     /db_xref="GeneID:207209"
                     /db_xref="MGI:MGI:2685163"
                     /translation="MSEPADGPSLRLSPSHLSTVTLEDLELLLTEGLVSAETSERDEC
                     SGRASGSLVPEQDTSKLWKQLEQWVAELQAEVVRLRGHKERCEHATLGLLRELLQVRA
                     RVQMQASELRQLRQVVQQAAWSPEKEELELSGPQSQNQMQTLDKRLVEVREALTHIRR
                     KQALQDSERKHSEQEINLRLTNLTGMLSQEEQGREAACSALQKNQEDTSQKVDLGLAK
                     MQAQMTKLNEEMSLRFLKREAKLCSFLQKSFLALEQRMKSSESTRQIAESSLREELES
                     RWQKLHELTEERLRALRAQREEEEGHLLEQCRGLDKAVVYLTKFVRQNQVSLNRVLMA
                     EQKAREAKVSLEETQAGELASYVHENLEAVQMAGKLAQQETQDALELLQEKSQVLEGS
                     VAGLDQQLKDLSDHCLALSWRLDLQEQTLGLKLSQKQAAWEGMERESLKDLVQWLKEV
                     TAHLEEVQEKVNSLPQQIESISNKCVIHKSEVDVKISAEGKAREFEVETVRQELAALL
                     MSVQLLKEENPGRKIAEIQGQLATFQKQMIKLENSLQANKTIQNLKFNNETKLRTEEI
                     ATLRESMLRLWSEEGPWPLTLGSKRVFMSLVRQRFFIKDVALDAMVSVNSWGVYQAVR
                     WLRWKRFLLNLVAQKRPGVTSAMTQWKPAYEVTSLTVFQK"
     exon            389..584
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            585..774
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            775..821
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            822..917
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1041
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1143
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1272
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1397
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            1398..1524
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            1525..1662
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            1663..1782
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            1783..1859
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            1860..1977
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            1978..2064
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            2065..2252
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     exon            2253..2407
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2372..2377
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /note="hexamer: AATAAA"
     polyA_site      2393
                     /gene="Ccdc154"
                     /gene_synonym="Ccdc157; Gm317; ntl"
                     /note="major polyA site"
ORIGIN      
        1 acctgcctcc gtcaggattc actaaagagg caaggtggaa gggcaggagc cactatatac
       61 ctccactact gctctctggg ctccacagcc tctctccctg actcaccccc tgaaggttca
      121 cagtctccat tctcgaccct tgtcttctcc ccaagattca ggccttccct cttgaccctc
      181 gagtctcctt gcctgctctg tggcccaaag ccttctcttc tgtccctcag ccaatcccca
      241 gctcctgcag ctttctgcct ggatcacttg cttctctcca gctaaccact cggccaccct
      301 ggcctggtgc ccaaccttgg gcagccacag gggctctgat aaccgttgtc tgagctatag
      361 gtggtggccg ctggtgaagc catgtcagag ccagcagacg gcccctcact aaggctttca
      421 ccttcacacc tgagcactgt cacactcgag gacctggagc tgctcttaac agaaggccta
      481 gtcagtgctg agacctcaga gagagatgag tgcagtggcc gggcgtccgg ctccttggtc
      541 cctgaacagg acacctctaa gctgtggaaa cagctggagc aatgggtagc tgagctgcag
      601 gctgaggtgg ttcgtctgag gggacacaag gaacgctgtg agcatgccac attgggcctg
      661 cttcgtgagc tgttgcaggt tcgtgcccgt gtgcagatgc aggcctcaga gctgcgccag
      721 ctgaggcaag tagtacaaca ggcagcctgg agcccagaga aggaggagct agagttatct
      781 gggccccaga gccagaacca gatgcaaacc ctggataaaa ggctggtgga ggtccgggag
      841 gctttaacac acatcaggag gaaacaggct ctacaggact cggagcggaa acattccgag
      901 caggagataa acctcaggct gaccaacctg actggcatgc tgagccaaga ggagcagggc
      961 cgggaagcag cctgcagtgc cttgcagaaa aaccaagagg acaccagcca aaaggtggac
     1021 cttgggttgg ccaagatgca ggcccagatg accaaactca acgaggaaat gagccttcgc
     1081 ttcctaaaga gagaggctaa actatgcagt tttctgcaga agagtttcct ggccttggag
     1141 cagagaatga aatcctcaga gagtacacgg cagatagcag aaagcagcct acgagaggaa
     1201 ctggaaagcc gctggcagaa gctgcatgag ctgacagagg agcgcttgcg ggccttgcgg
     1261 gcacagcgtg aggaggagga gggtcacctg ctggaacagt gccggggcct agacaaagct
     1321 gtggtctatc tgaccaagtt tgtgcgacag aaccaggtgt cactgaatcg tgtcctgatg
     1381 gctgagcaga aggctcggga ggccaaggtg agcttggagg agacccaggc cggggagttg
     1441 gcttcatatg tccatgagaa tctggaggct gtgcagatgg ctggcaagct agcccagcag
     1501 gaaacacagg atgcactgga actgctccaa gagaagagcc aggtcctaga ggggtcagta
     1561 gcagggctgg accagcagct gaaggacttg agtgaccact gtctagctct gagctggagg
     1621 ctagatctgc aggagcaaac actaggcctg aagctgtccc agaagcaggc tgcatgggaa
     1681 ggtatggaga gagagtccct gaaggatctg gtccagtggc tgaaagaagt cacagcacac
     1741 ttggaggagg tgcaggagaa agtgaacagc ctcccccaac agatagaaag tatctccaac
     1801 aagtgtgtca ttcacaaaag tgaagtggat gtgaagatct ccgctgaggg caaggccagg
     1861 gagtttgagg ttgagactgt gcgacaagag ctagctgccc tgctgatgtc tgtgcagctt
     1921 ctgaaagagg agaaccctgg acggaagatt gctgagatcc aggggcagct ggccacgttt
     1981 cagaagcaaa tgataaagtt ggagaacagc cttcaggcca acaaaaccat ccagaacctg
     2041 aagtttaata atgagaccaa gctgcgcaca gaggagattg caaccctgcg tgagagcatg
     2101 ctgcgcctgt ggagtgagga gggtccctgg ccactgaccc tgggcagcaa gcgggtattc
     2161 atgtccctgg tgaggcagcg gttcttcatc aaggacgtag ccctggacgc aatggtctct
     2221 gtgaactcct ggggagtgta ccaggctgtg aggtggcttc gttggaagag attcctcttg
     2281 aacttggtgg cccagaaaag gcccggagtg acctcagcga tgacccagtg gaagcctgca
     2341 tatgaggtca catctctgac tgtgttccag aaataaacat gccagttctt gtacctactg
     2401 gcgccag
//
