LOCUS       NM_172428               2073 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus coiled-coil domain containing 134 (Ccdc134),
            transcript variant 1, mRNA.
ACCESSION   NM_172428
VERSION     NM_172428.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2073)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2073)
  AUTHORS   Zhang,T., Shi,Q., Gu,H., Yu,B., Yin,S., Ge,Q., Mo,X., Liu,X. and
            Huang,J.
  TITLE     CCDC134 facilitates T cell activation through the regulation of
            early T cell receptor signaling
  JOURNAL   Front Immunol 14, 1133111 (2023)
   PUBMED   37234153
  REMARK    GeneRIF: CCDC134 facilitates T cell activation through the
            regulation of early T cell receptor signaling.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2073)
  AUTHORS   Yin,S., Liao,Q., Wang,Y., Shi,Q., Xia,P., Yi,M. and Huang,J.
  TITLE     Ccdc134 deficiency impairs cerebellar development and motor
            coordination
  JOURNAL   Genes Brain Behav 20 (7), e12763 (2021)
   PUBMED   34382738
REFERENCE   4  (bases 1 to 2073)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2073)
  AUTHORS   Yu,B., Zhang,T., Xia,P., Gong,X., Qiu,X. and Huang,J.
  TITLE     CCDC134 serves a crucial role in embryonic development
  JOURNAL   Int J Mol Med 41 (1), 381-390 (2018)
   PUBMED   29115376
  REMARK    GeneRIF: The present results suggest that Ccdc134 may have specific
            biological functions in regulating mouse embryonic development
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ106860.1, AK145747.1 and BC072586.1.
            
            On Oct 19, 2006 this sequence version replaced NM_172428.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC072586.1, AK145747.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                CJ106860.1         2-54
            54-2043             AK145747.1         2-1991
            2044-2073           BC072586.1         1988-2017
FEATURES             Location/Qualifiers
     source          1..2073
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 38.47 cM"
     gene            1..2073
                     /gene="Ccdc134"
                     /gene_synonym="2310042L06Rik"
                     /note="coiled-coil domain containing 134"
                     /db_xref="GeneID:76457"
                     /db_xref="MGI:MGI:1923707"
     exon            1..128
                     /gene="Ccdc134"
                     /gene_synonym="2310042L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            129..247
                     /gene="Ccdc134"
                     /gene_synonym="2310042L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            248..369
                     /gene="Ccdc134"
                     /gene_synonym="2310042L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            370..454
                     /gene="Ccdc134"
                     /gene_synonym="2310042L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            455..636
                     /gene="Ccdc134"
                     /gene_synonym="2310042L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            637..708
                     /gene="Ccdc134"
                     /gene_synonym="2310042L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            709..2046
                     /gene="Ccdc134"
                     /gene_synonym="2310042L06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2006..2011
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc134"
                     /gene_synonym="2310042L06Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2046
                     /gene="Ccdc134"
                     /gene_synonym="2310042L06Rik"
                     /note="major polyA site"
ORIGIN      
        1 gggccggccg cttgtcggtc tcctagcact gctggccggt tgctgtagag ttccgcgcct
       61 tgccagagtt gggtgcttcc ggctgctcgc caaggggctg ctcccttctc cctgcaccgc
      121 cggccgggct ccagaatctc agatatggac cttcttcagt tcctggcagc cttctctgtc
      181 ctcctgtggc ctggcacgga agtcacaggc gccctgaaga gcactctgga cccgagcctc
      241 aagatttaca agaagatgtt tgaggtgaag cggcgagagc agctgttggc actgaagaac
      301 ctggcgcagc tgaatgacat ccaccagcag tacaagatcc tggatgtcat gcttaaggga
      361 ctcttcaagg tgctggagga ctcccgcaca gtgctcattg ctgccgatgt gcttccagac
      421 gggccggtcc cccaggatga gaagctgaag gatgctttct cgcacgtggt ggagaacaca
      481 gccttttttg gtgacgtcgt gctgcgcttc ccaaagattg tccaccacta ctttgaccat
      541 aattccaact ggaacctcct gatccgctgg ggcatcagct tctgcaacca gacaggcgtc
      601 tttgaccagg ggccccactc acccatcctc agcctgatgg cccaggagct ggggatcact
      661 gagaaagatt ctgacttccg gaacccgttt aaaacagacc agacagagtt tattcctagc
      721 accgaccctt tccagaaggc tttgagggaa gaagaaaaac gccgcaagaa ggaggagagg
      781 cggaaggaga tccggaaagg cccgaggatt tcaagatccc agtctgagtt gtagccctgg
      841 accagctagg ggcctaagga atcagcaatg gccagtcaga agaggcagca actgtgtggc
      901 tgtggaatag gcccagcaag caccttgctg agcaccagcc acttcctgat gggaactgtt
      961 tgctgcgccc tcagaagcca gggttgagct ctggccaaaa agactgagct tccagggtct
     1021 tgcagcacac cacagaaagg acactgctcg gcagacagga tcatgcaggg aagctgcggg
     1081 aggaggctgg ctgaaggaac ttctggcctg gatccccttg gtgagggcag gctgcaggcc
     1141 actgccgccc ttgataagga agcaacagaa ccaggctctg agttacaagt gaaggtgcta
     1201 tgcttgcagc cagtctcact gtgttcctgg gctgcctgtc actggtccag ctctctgcag
     1261 aacagtacta aaagctagca aatccactgg cctcccccag gctggtgagg agaatgtaag
     1321 gggcagcagg aactgctgca gatgtcagga ccagcctgga gaacgtttct gcctcggaaa
     1381 gagggagtcc ctggctctgc agtgcagaga agcaagagct aggcttaggt ctctctctct
     1441 ctctctctca ctcactgctg cccttcatga caggccagtt tccagagggg actcagaagt
     1501 gtcctgagag ggtgtttatt tcaaggagac cttaaaagaa catgatctct attctcagat
     1561 aactggggac agtcattgag ctggttcagg ggacaatcaa cttgttctct ctgctgctaa
     1621 aagatcctgt ctatggggga caggttgcag gaggctgtgc tttgtgatgg gatactgtag
     1681 ctggattgac tagacagtgg ctcagagtcc cgtggccaca gagcaggagg ctacagagca
     1741 ggaagctatg caaggagtta ggccttcaga aggcagcctg gtttctatga gtctcaaggc
     1801 aggtggctgc cttggttcta ttgaaattac agctccacct ctttgatctt gccaagccaa
     1861 aatgtatcgc ttataggagt ggagacaccc cagcccgacc tctaccttca agtgcaggtg
     1921 ttgctaacag tgctcaattg agacctgagt cttagcctga cctgtcctgt tctttctctt
     1981 ccctgtgctg tgccttcatt ggtaaaataa atttgatggt gtctgaatcc tctgacaagc
     2041 tctaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
