LOCUS       NM_175369               1780 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus coiled-coil domain containing 122 (Ccdc122),
            transcript variant 1, mRNA.
ACCESSION   NM_175369
VERSION     NM_175369.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1780)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1780)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK077161.1 and AW554226.2.
            
            On Jul 17, 2015 this sequence version replaced NM_175369.3.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077161.1, BC138881.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1721              AK077161.1         2-1722
            1722-1780           AW554226.2         1-59                c
FEATURES             Location/Qualifiers
     source          1..1780
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 40.63 cM"
     gene            1..1780
                     /gene="Ccdc122"
                     /gene_synonym="4933415L06Rik"
                     /note="coiled-coil domain containing 122"
                     /db_xref="GeneID:108811"
                     /db_xref="MGI:MGI:1918358"
     exon            1..200
                     /gene="Ccdc122"
                     /gene_synonym="4933415L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            201..294
                     /gene="Ccdc122"
                     /gene_synonym="4933415L06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             249..1121
                     /gene="Ccdc122"
                     /gene_synonym="4933415L06Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     coiled-coil domain-containing protein 122"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 122
                     isoform 1"
                     /protein_id="NP_780578.1"
                     /db_xref="CCDS:CCDS27288.1"
                     /db_xref="GeneID:108811"
                     /db_xref="MGI:MGI:1918358"
                     /translation="MSGDTERKNEVIPTKAAVKDTSALTDAVEQVAKQQQSQTSEIEK
                     HKKILFQLQIELHELEKQIATIAEEAKETDRQMHRQDAAMENSKLQCGRLEAQIESLY
                     SESLKLKFDTETAQEKFEEQMIKYNAYYVKIKAYKDNLGEIKSQCPFMTELYEKRDLI
                     KNLKTMKEDLMENLQDSQGNCTIQIQEDISEIKNKIMTVKESITEKTSFVEEEKKTHE
                     KLRKEIEVQHKRYDAILKRLHCQMNKIQLNRRKWQWNIQQLEKTAAELKKRIREKEAS
                     EIQSRPAAPWERIL"
     exon            295..407
                     /gene="Ccdc122"
                     /gene_synonym="4933415L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            408..806
                     /gene="Ccdc122"
                     /gene_synonym="4933415L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            807..923
                     /gene="Ccdc122"
                     /gene_synonym="4933415L06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1780
                     /gene="Ccdc122"
                     /gene_synonym="4933415L06Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtcaccgtg gaggccgcct gaggcccggg cgctgaggcg cgggggcccg gagagccgcg
       61 ggcgagcgcg tcccgtgagg cgcccggaag ggaagggaag aagcgtcccc tctccccgcg
      121 ggccgtggcg actccagaag gatctgctga cccagcagtg tggccagctt gtcacttagc
      181 gccctccaat ccgggctcaa gagaaaagaa agcaaaccaa tccagggaaa agaattacca
      241 gacaaagaat gtcaggagac acagaaagga agaatgaagt cattcctaca aaagctgcag
      301 tcaaagacac atctgcatta actgatgctg tagagcaagt cgccaaacaa caacagtcac
      361 aaacatcaga aatagaaaaa cataaaaaaa ttctgttcca gttgcagatt gaacttcatg
      421 agcttgaaaa acaaatagcg actattgctg aagaagctaa agaaacagac aggcaaatgc
      481 atcggcaaga tgctgcaatg gagaactcta aacttcagtg tggacgctta gaagctcaaa
      541 ttgagtcctt atattcagaa agtttaaaac ttaaatttga tacagaaaca gcccaagaaa
      601 aatttgagga gcaaatgata aaatataatg catattatgt aaaaataaaa gcttataaag
      661 ataatttagg agagataaaa agccaatgtc catttatgac tgaactctat gaaaaacgag
      721 atcttatcaa aaacctaaag acaatgaaag aagatcttat ggaaaacctc caagattcac
      781 aagggaactg cacaatacaa atacaggaag acatttcaga gataaagaat aaaattatga
      841 cagtaaaaga gtcaatcact gagaaaacgt cttttgtgga agaagagaaa aagacacatg
      901 aaaaattaag aaaagaaata gaggtacaac ataagagata tgatgcaatt cttaagcgtt
      961 tgcattgtca gatgaacaag attcagttaa ataggaggaa gtggcaatgg aacatccaac
     1021 aactggaaaa aactgcagct gagttaaaaa agcggatcag agagaaggaa gccagtgaaa
     1081 tacagagcag gcctgcagca ccgtgggaga gaatactgtg aagttcctct ggactcttaa
     1141 cagcccacac atagtatcag aggcctgtct caatgacaga tattgtcttt ttccttttct
     1201 tcctccgctt ccttcttttt ctgttttgaa tcaggtatct gttggttaaa gtgtcttcct
     1261 gtctatagtg catagcacta ggtagacaaa agcagtgttt acaggaaact agcagaacac
     1321 tgtatgtgca tctttcaaat gtgctttcct gaatgcttgt ttataactgt tgaattcact
     1381 atcttacaaa ttaaaaattt ggaagaaaca attggatttt caatgatgta agttgctgag
     1441 ataaatagtt gtctgtttaa gaattttttt acaactgtct tcaaagtagc ccttaaatat
     1501 taatattcat gataatgtca ttatctgttt tattgtttcc tcctttctcc agaaggtagc
     1561 aatcattttc ctttgttatt aaataacata tattagagtg ttatagtaca taagatttgt
     1621 gtttactctt cagtctataa attctttatt cctatattgt gactaaaata aagttatagc
     1681 atcatatgag gcaggcataa aataaagctc ttcaaagagg tatttttcca cattgaaagg
     1741 caattttttt tgtcaatggc aataaattga atgtaaaaac
//
