LOCUS       NM_207202               3641 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus coiled-coil domain containing 120 (Ccdc120), mRNA.
ACCESSION   NM_207202 XM_620948
VERSION     NM_207202.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3641)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3641)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 3641)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 3641)
  AUTHORS   Brunkow,M.E., Jeffery,E.W., Hjerrild,K.A., Paeper,B., Clark,L.B.,
            Yasayko,S.A., Wilkinson,J.E., Galas,D., Ziegler,S.F. and
            Ramsdell,F.
  TITLE     Disruption of a new forkhead/winged-helix protein, scurfin, results
            in the fatal lymphoproliferative disorder of the scurfy mouse
  JOURNAL   Nat Genet 27 (1), 68-73 (2001)
   PUBMED   11138001
REFERENCE   5  (bases 1 to 3641)
  AUTHORS   Means,G.D., Toy,D.Y., Baum,P.R. and Derry,J.M.
  TITLE     A transcript map of a 2-Mb BAC contig in the proximal portion of
            the mouse X chromosome and regional mapping of the scurfy mutation
  JOURNAL   Genomics 65 (3), 213-223 (2000)
   PUBMED   10857745
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY023242.1, BC053918.1, BU505792.1 and AL671995.4.
            
            On or before May 25, 2005 this sequence version replaced
            XM_620948.1, NM_207202.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC053918.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-78                BY023242.1         19-96
            79-888              BC053918.1         42-851
            889-1565            BU505792.1         99-775
            1566-3641           AL671995.4         41360-43435         c
FEATURES             Location/Qualifiers
     source          1..3641
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 3.48 cM"
     gene            1..3641
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /note="coiled-coil domain containing 120"
                     /db_xref="GeneID:54648"
                     /db_xref="MGI:MGI:1859619"
     exon            1..113
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /inference="alignment:Splign:2.1.0"
     exon            114..267
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /inference="alignment:Splign:2.1.0"
     exon            268..358
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /inference="alignment:Splign:2.1.0"
     CDS             310..2199
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 120"
                     /protein_id="NP_997085.2"
                     /db_xref="CCDS:CCDS29972.1"
                     /db_xref="GeneID:54648"
                     /db_xref="MGI:MGI:1859619"
                     /translation="MEVKGQLISSPTFTAPAALFGEAAPLVKSDRLRGLLDRQRALQE
                     ALSVKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPAARAYPPPHPNPAHH
                     SLCPAEELALEALEREVSVQQQIAAAARRLALAPDLNGEQRRRRRQVQVDALRRLHEL
                     EEQLRDFRARLGLPVLQPLPLSAGALVNAQGVCLGTRLAQLSQEDVVLHSESSSLSES
                     GASHDNEEPHSCFPLTERPSPPKAWDQFRAVSGGSPERRAPWKPPPSDIYGDLKSRRN
                     SVASPTSPTRSLPRSASSFEGRSVPATPVLTRGSGPRLCKPEGLHSRQWSGSQDSQMG
                     FPRPDPASDRASLFAARTRRSNSSEALLVDRAAAGGAGSPPAPLAPPAAGPPVCKSSE
                     VLYERPQPVPSFSSRTTGPPDPPRAARPSSAAPASRGAPRLPTVCGDFLLDYPLDRGL
                     PRGSGGAGWGELLPAPEVPGPLSRRDGLLAMLPGPPPIYAADGSSPLLRSKDPNTRAI
                     RSKPSGLPPEAVEGLEVHPNPLLWMPPPTRIPPAGERGGHKNLALEGLRDWYIRNSGL
                     AVGPQRRPMLPHVGPTHTPFLHARCYEVGQSLYGPPSQAPLPHSRSFTAPPVSGRYGG
                     AFTDG"
     exon            359..492
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /inference="alignment:Splign:2.1.0"
     exon            493..633
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /inference="alignment:Splign:2.1.0"
     exon            634..919
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /inference="alignment:Splign:2.1.0"
     exon            920..982
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1157
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1256
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /inference="alignment:Splign:2.1.0"
     exon            1257..3641
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3623..3628
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /note="hexamer: AATAAA"
     polyA_site      3641
                     /gene="Ccdc120"
                     /gene_synonym="DXImx50e; Jm11; Sfc25"
                     /note="major polyA site"
ORIGIN      
        1 agccaagaca gcagtcactg ctgttcactt gtactgccag gaaagctagg gcctggacga
       61 gacaactgtt cttttggaaa tatttgaggc tgccatccag cactagggca ttggtgagac
      121 tcctggctgt ggcctatggg cctctgagga ggtgttgtaa gtctgcccag cttcccactt
      181 actgtgttag cactcaatgg gaagggaacc aaggtaccag gccaagcggg tccagacatt
      241 gacacagaat ctgagaggaa aggccaggct ttatccagcc atcagccaca aggtccaagc
      301 ggtgcaagga tggaagtcaa aggtcagctg atcagttctc ctaccttcac ggccccagct
      361 gccctgtttg gagaggctgc cccactggtg aagtcagacc gtcttcgagg gctgcttgac
      421 cgccagcgag ccttgcaaga ggccctgagc gtaaaacttc aagagctcag gaaagtgtgt
      481 ctgcaggagg cggagctaac tggtcagctg ccccctgagt gcccactgga gcctggtgaa
      541 cgacctcagt tggtccgccg gaggccccct gcagcacgtg cctaccctcc accacaccca
      601 aacccagcac accactcctt gtgtcctgct gaggaactgg ctcttgaggc cttggagagg
      661 gaggtatcgg tgcagcagca gattgcagct gctgcccgcc gcctggccct ggcccctgac
      721 ctcaacggag aacagaggcg gcgcaggcgc caggtacagg ttgatgcact tcgaaggctg
      781 cacgagctgg aggagcagct cagggacttc cgggcccgtc ttggcctccc ggtgctccag
      841 ccactgccac tgtctgcagg agcactagtc aatgcccagg gtgtctgcct gggtacacgc
      901 cttgctcagc tcagccaaga ggatgtagtt ctgcactcgg agagcagctc cctctcagag
      961 tcaggggcca gccatgataa cgaggagcct catagctgct tccctctaac ggagcgcccc
     1021 tcaccaccaa aagcgtggga ccagtttcgg gcagtatctg gggggagccc tgagcgacga
     1081 gccccatgga aacctccacc atcagatatt tatggggacc tgaagagccg acgcaactct
     1141 gtggccagcc ccaccagccc cacacgctcg ctgcccagga gtgcctccag ttttgagggg
     1201 cgaagtgtgc ctgctacccc tgtcctcacc cggggcagtg gcccccggct ctgcaaaccg
     1261 gaaggcctcc attctcgcca gtggtccggt agtcaggact cccagatggg ctttcctcgg
     1321 cctgaccctg cttcggatcg ggcctccctc ttcgcagctc gtacccgccg cagcaatagc
     1381 tctgaggccc tgctggtgga ccgcgcagct gctggcggag ctggatctcc acctgccccg
     1441 ctggctcccc ctgctgctgg tcccccagtt tgcaagagca gtgaggtgct gtatgagcgc
     1501 ccgcaaccag tcccttcctt ctcttcccgt accactggcc ccccagaccc tcctcgggct
     1561 gccaggccta gctcagctgc ccctgcatcc cgtggcgccc cccggctccc aactgtgtgt
     1621 ggagacttcc tcttggacta tccattggac cgaggcttgc cccgcggtag tggcggggca
     1681 ggttgggggg agctgctgcc tgctcctgag gtcccaggac ccctttcccg cagagatggg
     1741 ctccttgcca tgctcccagg tcctccaccc atatatgcag ctgatggcag cagccccctc
     1801 ctccgcagca aggaccccaa cacccgtgcc atccgttcca agcccagtgg cttaccccca
     1861 gaagctgtgg agggtctgga agtgcatcca aatccattac tctggatgcc cccacccact
     1921 cggatacctc cagctggaga gcgaggtggc cacaagaacc ttgccttgga ggggctgcgg
     1981 gactggtaca tccggaactc gggactggca gttggtcccc agcgcaggcc aatgctcccg
     2041 cacgtggggc caacacacac ccccttcctc catgcccgct gctatgaggt gggccagtca
     2101 ctctatggcc ctcccagcca ggcaccgctc ccgcactcca ggagttttac agcgccccct
     2161 gtctctggca ggtatggggg tgcttttact gatgggtagg gttattgatt cagatgctga
     2221 aggtatcctg accggggagc aaggaccaca aggcaatggg ctatagtagc tatcagacat
     2281 aacttttatt attagtcctt ggggtcctgg tgaggaggaa cttgggtgtt ggtagcagtt
     2341 ctttcccaag ctttagaagg ggttttctat tctccctagt gtatggcagc tggcagtgag
     2401 ccttgaagtc cgggtaatgg gagaaaggga cttgtgctat ccctggcttt ctcttccaag
     2461 cttaccccat gcttgagaac ctgaaggtgc tgtcctgtac ctgtctccac ctctttaaca
     2521 gcttcttttc ctctctctgt gtgtgtcctc tccgtctttt cctctctcac cttgtcttcc
     2581 ctacctgtct tcccgattcc tgctgtcctc cctttctaaa gatactacac ggatttcctg
     2641 tatcccccgg agctgagcgc tcgtttaagt gacctgacgc tagaggggga gccgtcttcc
     2701 agttctgaca cccagacacc agggacactg gtctgaccct aagccctgtg tcggtctgga
     2761 caaactccag tctgaggagc acacagtcaa cctcgctgag ccctgagatg tggtggctct
     2821 ttgtcctgag ggacacttgc ctgatctcac aggacccctg gcttcttttt ggcccaggaa
     2881 gatatctgat actcctgctt ctcttctcat cctgtgctgg gggaactgga gggccccagc
     2941 tagcttcaaa gactctaccc ctccctccat ttctgtttac agttgtgatt tagtactctg
     3001 tcattgccca acactaggtg ttttataaaa gggaaactgt gagctcgttc ctggttgggt
     3061 tcattcctgt ccccatgacc aacctgttcc attccagagc caccaccacc ctgcctcaac
     3121 aaaatggacc ataaagagtc tctggggctg ggagactgct gggaacagaa ttccctgctt
     3181 cctcccgcta gagtctttga gcagatgggc agcgggcttc tgtccacatt tggaaggatg
     3241 gaagtctaag tgggggtacc tgaaggagct ctgtctctgt ctctgcccaa tcagaaggcc
     3301 gtacaagagg ttgtcaagaa acagagccat ttgagtatgt tgcatcctgt gatgctgcag
     3361 tggctaaacc tggcagctag tacatgccag tcaaaccctc aggtgacatc tggccatggg
     3421 ttgcaggcca catcatgtcc tccttggcat tccttctttt accacttttt aaacaaatcc
     3481 acataagctg tgttttctat attgtctgtg actttctgga gctgggggtt cccctgcccc
     3541 cgttacctgg tgtttaaaat tttctttttg taccaatgga tctgggccca agacactact
     3601 cacactggaa ggggatttct ataataaatg tataaactga a
//
