LOCUS       NM_134033               3418 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus coiled-coil domain containing 117 (Ccdc117), mRNA.
ACCESSION   NM_134033
VERSION     NM_134033.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3418)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3418)
  AUTHORS   Horton,A.J., Brooker,J., Streitfeld,W.S., Flessa,M.E., Pillai,B.,
            Simpson,R., Clark,C.D., Gooz,M.B., Sutton,K.K., Foley,A.C. and
            Lee,K.H.
  TITLE     Nkx2-5 Second Heart Field Target Gene Ccdc117 Regulates DNA
            Metabolism and Proliferation
  JOURNAL   Sci Rep 9 (1), 1738 (2019)
   PUBMED   30742009
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3418)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   4  (bases 1 to 3418)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BQ768997.1 and BC059888.1.
            
            On Jan 15, 2008 this sequence version replaced NM_134033.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC018601.1, SRR1660811.122542.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-505               BQ768997.1         1-505
            506-1730            BC059888.1         461-1685
            1731-3418           BC059888.1         1687-3374
FEATURES             Location/Qualifiers
     source          1..3418
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 3.61 cM"
     gene            1..3418
                     /gene="Ccdc117"
                     /gene_synonym="1110004K02Rik; 1700026O03Rik"
                     /note="coiled-coil domain containing 117"
                     /db_xref="GeneID:104479"
                     /db_xref="MGI:MGI:2144383"
     exon            1..341
                     /gene="Ccdc117"
                     /gene_synonym="1110004K02Rik; 1700026O03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             160..993
                     /gene="Ccdc117"
                     /gene_synonym="1110004K02Rik; 1700026O03Rik"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 117"
                     /protein_id="NP_598794.2"
                     /db_xref="CCDS:CCDS24401.1"
                     /db_xref="GeneID:104479"
                     /db_xref="MGI:MGI:2144383"
                     /translation="MAALGRPFSGLPLSGSADFLQPPPAFAGRAFPPGAAGHDLAPRP
                     GVRGAPSSPGGRTARGRVSIHCRKKHKRLAEDDECPVRKKRLTEAELGAVTDEWALGA
                     HQGREGHGVNTCPSSLSMPSMLDVVCEEMDQTTGEPQCEVARRRLQEIEDRIIDEDEE
                     VESDRNVSHLPSLVLSDTMKTGLKREFDEVFTKRMIESMSRPSMELVLWKPLPELLPE
                     KPKPSSSPKNYRRESQAKHAAPGTAFPQRTEGLLEPQCADAPLYRSLEAATSTEEEME
                     L"
     exon            342..392
                     /gene="Ccdc117"
                     /gene_synonym="1110004K02Rik; 1700026O03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            393..617
                     /gene="Ccdc117"
                     /gene_synonym="1110004K02Rik; 1700026O03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            618..755
                     /gene="Ccdc117"
                     /gene_synonym="1110004K02Rik; 1700026O03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            756..3402
                     /gene="Ccdc117"
                     /gene_synonym="1110004K02Rik; 1700026O03Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3374..3379
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc117"
                     /gene_synonym="1110004K02Rik; 1700026O03Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3402
                     /gene="Ccdc117"
                     /gene_synonym="1110004K02Rik; 1700026O03Rik"
                     /note="major polyA site"
ORIGIN      
        1 tctctgggcg gtccggagtg gagggttcta gaaggcgtga ggttgggggg ccgaagaggg
       61 ctcagaggca ggtaatcgtg ggtagcgttg gtggcggcca ctgcggagtc tgggaaaacg
      121 aacgactggg gtcgcggacg cagcctcgtc tggaaagcca tggcagccct cggccggccc
      181 ttcagcggcc tccctctgag cggcagcgcg gacttcctgc agccgccacc ggccttcgcg
      241 ggccgggcct tcccgccagg agccgccggc catgacctgg ccccgcggcc cggtgtccgc
      301 ggcgcgccga gcagcccggg cgggagaaca gcgcgcggac gtgtttccat tcactgtaga
      361 aagaaacaca agcggttggc ggaggatgat gagtgtccag taagaaagaa acgactgact
      421 gaagctgaac tcggtgcagt tactgatgaa tgggctctcg gcgcacatca gggaagagaa
      481 ggtcatgggg taaacacgtg tcctagcagc ctttctatgc ccagcatgct agatgtggtc
      541 tgtgaggaaa tggatcagac aactggagaa ccacagtgtg aagtcgcccg aaggcggctg
      601 caagagattg aggacaggat aattgacgaa gatgaagagg ttgaaagtga cagaaatgtt
      661 agccacctcc caagtcttgt cctttctgac accatgaaaa cgggtttgaa gagggaattt
      721 gatgaagtct tcacaaagag gatgattgag tctatgagcc gtccttctat ggagcttgtg
      781 ctctggaaac ctctccctga actccttcct gagaagccaa agccatcatc tagccctaag
      841 aactacagga gagagagcca agcaaagcac gcagctccgg gcactgcgtt cccacagagg
      901 actgaagggt tgctggaacc tcagtgcgca gacgcgccgc tttaccgtag tctggaggca
      961 gctactagca cagaggagga gatggagctc tagacacccg ttctgctcta acttgacaag
     1021 tcggagaagg ctcctgcgtt cagaaatgag cctgcctgca gagtataggg gcctgaaagt
     1081 tttatgaaac gggtgtaata tctcctctgc ctgtgacttg ggtgggactg tcattgtggg
     1141 tagccattta ttgaattcaa ctttttgcca aggaagctta tctcaaggga aatgcagttt
     1201 tttaataggc ttatccagga aatgttacag tctctttaac gacagctata gatgctggat
     1261 gtgttccgat gacttaggtc atgtcacatt gttgaagcca ttcattcttg agatgattct
     1321 gtacaggagt gctcctaatc gccactgcac cctaattgct gagtcatgtg ctgagctact
     1381 tgtagtggtc actgtacacg tggggctcgg gagggaagag agcaggactt gtctcttgtg
     1441 aaggaatgga acaagcaaag aaacttgtgt tggtgtcagg ttggtgtagc tggatcaccc
     1501 aagtagtagc ccttgatctc ctttcatgac ggataggctc agttagtcag gaatgtttac
     1561 acctcagtta acttcagtga ttgacttaaa gactgggagg tatattgcct gtgagagaaa
     1621 tgtcttttca tgaatcctaa ggacatgctg tgtcagctaa acctacaatt gattgcttct
     1681 agagtttaaa aagggaaagt tgtgcttgta tttgcaagtt gaattttttt aatgttggtt
     1741 ccaaaaacag tgaattagct gaaaagaaat ggagaagtgt cttggagatt tactgaaata
     1801 gctaattgtc aggtgcttaa gcttttgtgc agtaagccta aaagttagca gaagatggcc
     1861 tcctgccagc aggaaatctt taccctttag tacccgaacc agtctcaagg tgttctttgg
     1921 aaataaccag ggttaaagtt tttaatttct caggaagagc tcttcagcat ggcaggacgt
     1981 gtaatgaggg ctttcgcaag tccttcagcg ctgcagagca gtaagctatc catccagtga
     2041 gtgtggcggc tctttctaca gctgaactcc tcctcagttg agttttcagt ttctggcttg
     2101 cttctccctt tgtatagggg agaacagaga agaggtttat gctgaggggg ggtgactttt
     2161 tagaaacgta gcttcttggc gttttgcaac ccatgctggc ctccctcctg cagatggcat
     2221 aggagtccgt ctgtctttgg actgtctcct ctgctgttgt tcctgctctc tccgtttctg
     2281 tctagatgtc aggaaaaggt ttaatgttta atatttaaac aaaatattta tatctacaca
     2341 ataaagttaa tcaaccttca aaccagtctt gaagccagct acttgtttct tcatctcaga
     2401 ctcctagggg aatgaaagct gtcttctgtg aatgtgcaag ggtttggctc gtgtcatttg
     2461 aaaactcctg gcttatctaa tgggaccagc ttgtgaagtt tatagcctta aagaaatctc
     2521 tgtgctaagt tttagaacag tttagaacca tgcagggatg ccgagagtct ggagttagcc
     2581 cagtgttagg gtaggaaggt agtggcagct ttccaaaggg cctaaaacac caggactgcc
     2641 tctgtgaaag gcccgagtgg ctttgatgca gttggtaacc acttgagagc agagatgtct
     2701 taacttgtca ggagtcctta cctgacatga ccctgtttca acaggaaagt agatgttttg
     2761 tgctcctttt tggattttat cttcttgcac atgtttgtac agaaatcacc ttcatccttg
     2821 tggtgcttac acacacccag ttgtctccac agctctgata cctttgcctt ctgttctcct
     2881 ctctagcata agactttggc ttctgcctta aggttttcct aaggaattaa caggtctttt
     2941 catcttgtat agtttttaca gtgtgaatcc aacattggct cagtatgcta atgtgacagt
     3001 caacagttat ctaaagcagg tgagctctga tgaacaaatg tattttcagt gagtctgagt
     3061 cgggtgtatg tgggtttttt ggttcttggc ttggggcttt ttgttgttgt tgttcttaat
     3121 aatatgagaa tccagttctc atgacaagaa ccagtttaaa aactgctcgt tcttaaaaag
     3181 gtaaaactaa gatttagaaa caaggcaggc cttagagccg agggagacta ttaggcagca
     3241 ggccaaacca ctctggccct ggagccgcct ttgttaacag caacaagaat gctgcagtgc
     3301 tacaacgtgc tggaagatgt gtcagatttg ctttaaagat gagaatctgg tgtttctgta
     3361 ctttattatt ttcaataaaa ctcaatgttt tgaactttta aaaaaaaaaa aaaaaaaa
//
