LOCUS       NM_026457               1473 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus chibby family member 2 (Cby2), transcript variant 2,
            mRNA.
ACCESSION   NM_026457
VERSION     NM_026457.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1473)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1473)
  AUTHORS   Oyama,Y., Miyata,H., Shimada,K., Fujihara,Y., Tokuhiro,K.,
            Garcia,T.X., Matzuk,M.M. and Ikawa,M.
  TITLE     CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched
            genes dispensable for male fertility in mice
  JOURNAL   Asian J Androl 24 (3), 266-272 (2022)
   PUBMED   34290169
REFERENCE   3  (bases 1 to 1473)
  AUTHORS   Li,Q., Ishikawa,T.O., Miyoshi,H., Oshima,M. and Taketo,M.M.
  TITLE     A targeted mutation of Nkd1 impairs mouse spermatogenesis
  JOURNAL   J Biol Chem 280 (4), 2831-2839 (2005)
   PUBMED   15546883
REFERENCE   4  (bases 1 to 1473)
  AUTHORS   Feige,E., Chen,A. and Motro,B.
  TITLE     Nurit, a novel leucine-zipper protein, expressed uniquely in the
            spermatid flower-like structure
  JOURNAL   Mech Dev 117 (1-2), 369-377 (2002)
   PUBMED   12204287
  REMARK    GeneRIF: immunogold electron microscopy revealed that the protein
            is restricted, from its first detectable appearance, to a unique
            spermatid organelle called the 'flower-like structure'
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK005703.1, AK007022.1 and AK006329.1.
            
            On Aug 19, 2009 this sequence version replaced NM_026457.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR, lacks a
            portion of the 5' coding region, and initiates translation at an
            alternate start codon, compared to variant 1. The encoded isoform
            (2) has a distinct N-terminus and is shorter than isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005703.1, AK007022.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                AK005703.1         1-23
            24-159              AK007022.1         3-138
            160-485             AK005703.1         159-484
            486-1430            AK007022.1         465-1409
            1431-1473           AK006329.1         1161-1203
FEATURES             Location/Qualifiers
     source          1..1473
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 40.23 cM"
     gene            1..1473
                     /gene="Cby2"
                     /gene_synonym="1700086N05Rik; Nurit; Spert"
                     /note="chibby family member 2"
                     /db_xref="GeneID:67926"
                     /db_xref="MGI:MGI:1915176"
     exon            1..71
                     /gene="Cby2"
                     /gene_synonym="1700086N05Rik; Nurit; Spert"
                     /inference="alignment:Splign:2.1.0"
     exon            72..1473
                     /gene="Cby2"
                     /gene_synonym="1700086N05Rik; Nurit; Spert"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1389..1394
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cby2"
                     /gene_synonym="1700086N05Rik; Nurit; Spert"
                     /note="hexamer: AATAAA"
     polyA_site      1424
                     /gene="Cby2"
                     /gene_synonym="1700086N05Rik; Nurit; Spert"
                     /note="major polyA site"
ORIGIN      
        1 gagctcactg gaagaccagg gtcatgcagc cagagggggt gaaatgtagg atggagggac
       61 ccaaggcaca gaggggcacc gagcccttcc tgaggctcca caacctgtac agtactcctc
      121 gctgctccag gcaggctgcc ttacctcgga tgagccgcag ggtagccagc cagcactcct
      181 acccactcaa ccgcttctct tctatgcctt ttgaccccat ggagcgcccc acctcccagg
      241 ccgacctgga actagactac aaccctcccc gggtgcagct cagcgatgag atgtttgtct
      301 tccaggatgg gcgctgggtg aatgagagct gccgcctaca accaccttac ttctctcccc
      361 cctcctcctt ccaccataag ctgcaccaca ggaggctggc caaggagtac cagctgcagg
      421 aagagaacaa gtctcttcgg gatgagaacc gggccctacg ggatgagaac aaggccctcc
      481 gcaaggagaa caagatctta caggtctttt gggaagagca caaggtcact ttaggccacg
      541 aggagagtca gacctcctca ttgttgcaca aggacacaac ctcccaggaa gtggtgaaga
      601 gagacaacac cactttgcct gcccagcgta gcaaagagag caccctacag ctcattcgag
      661 aggagaaccg ggccctgcag cagttgctgg agcagaggca ggcctactgg gcccaggcag
      721 aagagaatgc agcttccact gaggaaggca agtccacctc ctcacccaag gaggagtccc
      781 ataactcagg gcttctgcca gatcagagca caaaccactc ctcccccttt gaggacccca
      841 aagtgccccc cacaacacag gaggactcga agacactgcg tgccctgagg gagatggtta
      901 acaacttgtc tggggcatct ggggaagagg atggcaaagt aggccctaac ctacctgaca
      961 gcgctcaacc cctgcagctg ctgagagaga tgaaccaggc gctgcaggcc ctgcaggagg
     1021 agaaccggct gctgcaggag gagaacaggg ctctgcacat cttgcgagag gagcaccgcg
     1081 tcttccagga ggagaacaag gccctgtggg agaacaataa gttgaagctg cagcagcggc
     1141 tggtcatcga cacggtgact gaggtcacag cccggatgga gatgcttatc gaagagctgt
     1201 atgccttcat gccagccaag aacaacaaag atcccaaaaa gcccagcagg gtctgaggcc
     1261 ttggcagcag acatagacac caagaccaga ccagagagaa ccctcaacct tcctttgtct
     1321 tccttactct gcccagaagc acgtgcccgt gggacaacgg agaaagggcc atcctacacc
     1381 tgacacacaa taaagacaga ggaggctggg gccagccaac accagcgtgg aattatggct
     1441 tcttctcccc cttccttctt actctttaac gtc
//
