LOCUS       NM_019626               2345 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus cerebellin 1 precursor protein (Cbln1), mRNA.
ACCESSION   NM_019626
VERSION     NM_019626.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2345)
  AUTHORS   Song,J.H.T., Ruven,C., Patel,P., Ding,F., Macklis,J.D. and Sahni,V.
  TITLE     Cbln1 Directs Axon Targeting by Corticospinal Neurons Specifically
            toward Thoraco-Lumbar Spinal Cord
  JOURNAL   J Neurosci 43 (11), 1871-1887 (2023)
   PUBMED   36823038
  REMARK    GeneRIF: Cbln1 Directs Axon Targeting by Corticospinal Neurons
            Specifically toward Thoraco-Lumbar Spinal Cord.
REFERENCE   2  (bases 1 to 2345)
  AUTHORS   Liau,E.S., Jin,S., Chen,Y.C., Liu,W.S., Calon,M., Nedelec,S.,
            Nie,Q. and Chen,J.A.
  TITLE     Single-cell transcriptomic analysis reveals diversity within
            mammalian spinal motor neurons
  JOURNAL   Nat Commun 14 (1), 46 (2023)
   PUBMED   36596814
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2345)
  AUTHORS   Govek,K.W., Chen,S., Sgourdou,P., Yao,Y., Woodhouse,S., Chen,T.,
            Fuccillo,M.V., Epstein,D.J. and Camara,P.G.
  TITLE     Developmental trajectories of thalamic progenitors revealed by
            single-cell transcriptome profiling and Shh perturbation
  JOURNAL   Cell Rep 41 (10), 111768 (2022)
   PUBMED   36476860
REFERENCE   4  (bases 1 to 2345)
  AUTHORS   Han,P., She,Y., Yang,Z., Zhuang,M., Wang,Q., Luo,X., Yin,C.,
            Zhu,J., Jaffrey,S.R. and Ji,S.J.
  TITLE     Cbln1 regulates axon growth and guidance in multiple neural regions
  JOURNAL   PLoS Biol 20 (11), e3001853 (2022)
   PUBMED   36395107
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2345)
  AUTHORS   Dai,J., Liakath-Ali,K., Golf,S.R. and Sudhof,T.C.
  TITLE     Distinct neurexin-cerebellin complexes control AMPA- and
            NMDA-receptor responses in a circuit-dependent manner
  JOURNAL   Elife 11, e78649 (2022)
   PUBMED   36205393
  REMARK    Erratum:[Elife. 2023 Nov 09;12:e94305. doi: 10.7554/eLife.94305..
            PMID: 37943030]
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2345)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
REFERENCE   7  (bases 1 to 2345)
  AUTHORS   Fletcher,C.F., Lutz,C.M., O'Sullivan,T.N., Shaughnessy,J.D. Jr.,
            Hawkes,R., Frankel,W.N., Copeland,N.G. and Jenkins,N.A.
  TITLE     Absence epilepsy in tottering mutant mice is associated with
            calcium channel defects
  JOURNAL   Cell 87 (4), 607-617 (1996)
   PUBMED   8929530
REFERENCE   8  (bases 1 to 2345)
  AUTHORS   Kavety,B., Jenkins,N.A., Fletcher,C.F., Copeland,N.G. and
            Morgan,J.I.
  TITLE     Genomic structure and mapping of precerebellin and a
            precerebellin-related gene
  JOURNAL   Brain Res Mol Brain Res 27 (1), 152-156 (1994)
   PUBMED   7877445
REFERENCE   9  (bases 1 to 2345)
  AUTHORS   Slemmon,J.R., Goldowitz,D., Blacher,R. and Morgan,J.I.
  TITLE     Evidence for the transneuronal regulation of cerebellin
            biosynthesis in developing Purkinje cells
  JOURNAL   J Neurosci 8 (12), 4603-4611 (1988)
   PUBMED   3199194
REFERENCE   10 (bases 1 to 2345)
  AUTHORS   Morgan,J.I., Slemmon,J.R., Danho,W., Hempstead,J., Berrebi,A.S. and
            Mugnaini,E.
  TITLE     Cerebellin and related postsynaptic peptides in the brain of normal
            and neurodevelopmentally mutant vertebrates
  JOURNAL   Synapse 2 (2), 117-124 (1988)
   PUBMED   3420533
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK158885.1 and AI894057.1.
            
            On Mar 16, 2007 this sequence version replaced NM_019626.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK158818.1, AK158885.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849379
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2326              AK158885.1         19-2344
            2327-2345           AI894057.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..2345
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 42.16 cM"
     gene            1..2345
                     /gene="Cbln1"
                     /note="cerebellin 1 precursor protein"
                     /db_xref="GeneID:12404"
                     /db_xref="MGI:MGI:88281"
     exon            1..616
                     /gene="Cbln1"
                     /inference="alignment:Splign:2.1.0"
     CDS             353..934
                     /gene="Cbln1"
                     /note="precerebellin; brain protein D3"
                     /codon_start=1
                     /product="cerebellin-1 precursor"
                     /protein_id="NP_062600.2"
                     /db_xref="CCDS:CCDS22506.1"
                     /db_xref="GeneID:12404"
                     /db_xref="MGI:MGI:88281"
                     /translation="MLGVVELLLLGTAWLAGPARGQNETEPIVLEGKCLVVCDSNPTS
                     DPTGTALGISVRSGSAKVAFSAIRSTNHEPSEMSNRTMIIYFDQVLVNIGNNFDSERS
                     TFIAPRKGIYSFNFHVVKVYNRQTIQVSLMLNGWPVISAFAGDQDVTREAASNGVLIQ
                     MEKGDRAYLKLERGNLMGGWKYSTFSGFLVFPL"
     exon            617..736
                     /gene="Cbln1"
                     /inference="alignment:Splign:2.1.0"
     exon            737..2335
                     /gene="Cbln1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1744..1749
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cbln1"
                     /note="hexamer: AATAAA"
     polyA_site      1767
                     /gene="Cbln1"
                     /note="major polyA site"
     regulatory      2302..2307
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cbln1"
                     /note="hexamer: AATAAA"
     polyA_site      2329
                     /gene="Cbln1"
ORIGIN      
        1 tccgcccgct ccggctgcag cgcccgctgc atcaataatt cagagcggcg gcggcagcag
       61 cagcggcgag tgcggacagg aggcggcggc aacagcgggg accaggcagc agaggctatg
      121 catccaagtg cggctgggcg gccgcggcac ccctgaggcc cgggcggggc ttcgggcaca
      181 cggcacgcgg ggacatttgt tctggagtgc gagggagagg cgtagtggcc cgggaggcgt
      241 cggcagagct gcgcacagag ctgaggaggg ggcttcggag cagggctggg gaggggggcg
      301 gctggcgctg gcagcccccg gggtgggggg cggggtgggc gccggaggcg cgatgctggg
      361 cgtcgtggag ctgctgctgt tggggactgc gtggctggca ggcccagccc gcgggcagaa
      421 tgagacagag cccatcgtac tggagggcaa gtgcctggtg gtgtgtgact ccaaccccac
      481 gtctgaccct acgggcactg ctctgggcat ctctgtgcgc tccggcagcg ccaaggtggc
      541 tttctctgcc atcaggagca ccaaccatga gccgtccgag atgagtaatc gcaccatgat
      601 catctacttc gaccaggtac tagtgaacat cgggaacaac tttgactcag aacgcagcac
      661 tttcatcgcc ccgcgcaaag gcatctacag ttttaacttc cacgtggtga aagtctacaa
      721 cagacagacc atccaggtga gcctcatgtt gaacgggtgg ccggtgattt cagccttcgc
      781 cggtgaccaa gacgtgacac gcgaggccgc cagcaacggc gtcctcatcc agatggagaa
      841 aggcgaccga gcatacctca agctggagcg ggggaacttg atggggggct ggaagtactc
      901 aaccttctct ggattcctcg tgtttcccct ctgactggca cgtatcggga atggaggcag
      961 gagagaggca ggaggggagt gagaaagagg ccgaaaatta ccagggcgag gaagcggcgc
     1021 caccggaaac ttcctacgtg ttcgtagcta cactgggtac caaggtgcgc gccgccggcg
     1081 gtccaacttc gtccgctccc ttactaagag aagtaaattt cgcttagctc tgcacactcc
     1141 cgtttccaaa attaatctcg ccttccccaa gccagtcgca gtaatcgagg aagagacttg
     1201 ccttgtcatt atggttcctt acccacgtcc atgtccctaa caattaacga agtaatgtga
     1261 aatgtttctc ccgacccgac ccccctctga accctgccac ttactgaaac ttagtatgcc
     1321 cccctgcccc agtttgaaga gggggtcaga ttgttttttt gtttctgttt ccgaatgggg
     1381 caggtagttt taataacaga ttttgctctt caaacaccgc gccagttaag ctggagagaa
     1441 ttcgtccccg cttgttagcg aaggaaagac tcaccttcgt ggtgactggt ttgactatac
     1501 ataaatatgt atatgtatca tttgtacacg aagaactctt ccaggtggac gctggctgta
     1561 ttccgtattt ctgtcctgtt cggagtgatc gtgaaatcta aggctgcttg gtgtttgttc
     1621 tctgatgctt gtcaatgccc cgtgttctgt ggctccacca accgccaagg aggttcttcg
     1681 ggacgcttct tcttcctctg taacatacgt gtgaatagcc aaattttaat tttgctttaa
     1741 tccaataaag tcaaagtggg acttttattt ttctgaaaca gctttctaaa cttcgccttt
     1801 tccgggttgc gaggttgagg cgggcggaga agcaagagac ttggaagctg caaggagagg
     1861 ccagggcaca aggccttctt cgcagagcca tttctgcgct gtctcccgca gcaggctccc
     1921 tttgcctttc ctgtgtcccc tgctttggtg gaaagtgaga tataagacct aaatcctgct
     1981 aggcgtgacc gagggcctgg aagcagtttc ttgctcaccc tcaattccaa atgcatcagg
     2041 aattattccc aatcctagta ctcgaacccg cctgccccgc gtgactgtct tcacgcctac
     2101 tttccttgga tgtctccagc tctatccgct ccgcggcgcc cgaagcacct gacactttgt
     2161 accagcgcct ctgaacccga ggtccacccg ccaaacaaac ccgggcggcc ggactcgcga
     2221 ttgcgctcat tcgcaggact ttcaaggggt tcgtccagaa gttttgattg taccgaaaca
     2281 taatgtgcaa agcaaaattg aaataaacga cttcgtttta agtctggaac gctgaaaaaa
     2341 aaaaa
//
