LOCUS       NM_001195268            2978 bp    mRNA    linear   ROD 23-DEC-2022
DEFINITION  Mus musculus calcium channel, voltage-dependent, beta subunit
            associated regulatory protein (Cbarp), transcript variant 1, mRNA.
ACCESSION   NM_001195268
VERSION     NM_001195268.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2978)
  AUTHORS   Knowland,D., Gu,S., Eckert,W.A. 3rd, Dawe,G.B., Matta,J.A.,
            Limberis,J., Wickenden,A.D., Bhattacharya,A. and Bredt,D.S.
  TITLE     Functional alpha6beta4 acetylcholine receptor expression enables
            pharmacological testing of nicotinic agonists with analgesic
            properties
  JOURNAL   J Clin Invest 130 (11), 6158-6170 (2020)
   PUBMED   33074244
REFERENCE   2  (bases 1 to 2978)
  AUTHORS   Gu S, Matta JA, Davini WB, Dawe GB, Lord B and Bredt DS.
  TITLE     alpha6-Containing Nicotinic Acetylcholine Receptor Reconstitution
            Involves Mechanistically Distinct Accessory Components
  JOURNAL   Cell Rep 26 (4), 866-874 (2019)
   PUBMED   30673609
REFERENCE   3  (bases 1 to 2978)
  AUTHORS   Nakao A, Miki T, Shoji H, Nishi M, Takeshima H, Miyakawa T and Mori
            Y.
  TITLE     Comprehensive behavioral analysis of voltage-gated calcium channel
            beta-anchoring and -regulatory protein knockout mice
  JOURNAL   Front Behav Neurosci 9, 141 (2015)
   PUBMED   26136667
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2978)
  AUTHORS   Beguin P, Nagashima K, Mahalakshmi RN, Vigot R, Matsunaga A, Miki
            T, Ng MY, Ng YJ, Lim CH, Tay HS, Hwang LA, Firsov D, Tang BL,
            Inagaki N, Mori Y, Seino S, Launey T and Hunziker W.
  TITLE     BARP suppresses voltage-gated calcium channel activity and
            Ca2+-evoked exocytosis
  JOURNAL   J Cell Biol 205 (2), 233-249 (2014)
   PUBMED   24751537
REFERENCE   5  (bases 1 to 2978)
  AUTHORS   Smith DP, Spicer J, Smith A, Swift S and Ashworth A.
  TITLE     The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear
            protein kinase
  JOURNAL   Hum Mol Genet 8 (8), 1479-1485 (1999)
   PUBMED   10400995
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY280734.1, BY274870.1, BC078442.1 and BC100552.1.
            
            [WARNING] On May 18, 2023 this sequence was replaced by
            NM_001195268.2.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript but encodes the supported protein. There are no mouse
            full-length transcripts representing this exon combination; it is
            predicted based on partial transcript alignments and homology data.
            This RefSeq is incomplete at the 5' end due to lack full-length
            transcript support and splice pattern ambiguity in the 5' UTR.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164131,
                              SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-99                BY280734.1         54-152
            100-342             BY274870.1         182-424
            343-481             BY280734.1         261-399
            482-2843            BC078442.1         37-2398
            2844-2978           BC100552.1         2227-2361
FEATURES             Location/Qualifiers
     source          1..2978
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10"
     gene            1..2978
                     /gene="Cbarp"
                     /gene_synonym="9630008F14; Dos; R29144/1"
                     /note="calcium channel, voltage-dependent, beta subunit
                     associated regulatory protein"
                     /db_xref="GeneID:100503659"
                     /db_xref="MGI:MGI:1354170"
     exon            1..100
                     /gene="Cbarp"
                     /gene_synonym="9630008F14; Dos; R29144/1"
                     /inference="alignment:Splign:2.1.0"
     CDS             8..2104
                     /gene="Cbarp"
                     /gene_synonym="9630008F14; Dos; R29144/1"
                     /note="protein Dos; downstream of Stk11 protein"
                     /codon_start=1
                     /product="voltage-dependent calcium channel beta
                     subunit-associated regulatory protein"
                     /protein_id="NP_001182197.1"
                     /db_xref="CCDS:CCDS56734.1"
                     /db_xref="GeneID:100503659"
                     /db_xref="MGI:MGI:1354170"
                     /translation="MQPTATMATAAATTATVALTTSWDNATSRPTAEPDPILDNYVLL
                     VVVMSLFVGGTLVVLSGVLLLCKRCWEVHQRFNRAMEEAEKTTTTYLDNGTHPIQDPD
                     CRGEDPEGQDTETERFLATSSTGRRVSFNEAALFEQSRKAQDKGRRYTLTEGDFHHLK
                     NARLTHLHLPPLKIATIHECDSGEASAAATPHPATTSKDSLAIFQPPGKTLTGHSVGP
                     SSALPGGPYNSVDFSEISPSTSSDSGEGISLDAGTRGAKAAGPETVPGEMGTGSSGSG
                     TVLQFFTRLRRHASLDGASPYFKVKKWKLEPSQRASSLDTRGSPKRHHFQRQRAASES
                     MEQEGDVPHADFIQYIASAGDSVAFPPPRPFLASPTSPPPTLGRLEAAEAAGGASPET
                     PPEHGISLGPEHAQQQDPQQEQDAEHAQCSYRDLWSLRASLELHAATASDHSSSGNDR
                     DSVRSGDSSGSGSGGGGAAPAFPPPPESPPALRPKDGEARRLLQMDSGYASIEGRGAG
                     DEVSELPAPARSPPRSPRAWPRRPRRDYSIDEKTDALFHEFLRHDPHFDDAPRHRTRA
                     HPHTHARKQWQQRGRQHSDPGGARAATPPGVARPTRAPLRRGDSVDCPPEGRALPITG
                     DDPSIPVIEEEPGGGGGGCPGSGLCVEPAGALLDKLAASLDERLFSPRLAEPVASSQV
                     LIVAAAAPTSPDHSPA"
     exon            101..240
                     /gene="Cbarp"
                     /gene_synonym="9630008F14; Dos; R29144/1"
                     /inference="alignment:Splign:2.1.0"
     exon            241..305
                     /gene="Cbarp"
                     /gene_synonym="9630008F14; Dos; R29144/1"
                     /inference="alignment:Splign:2.1.0"
     exon            306..450
                     /gene="Cbarp"
                     /gene_synonym="9630008F14; Dos; R29144/1"
                     /inference="alignment:Splign:2.1.0"
     exon            451..622
                     /gene="Cbarp"
                     /gene_synonym="9630008F14; Dos; R29144/1"
                     /inference="alignment:Splign:2.1.0"
     exon            623..751
                     /gene="Cbarp"
                     /gene_synonym="9630008F14; Dos; R29144/1"
                     /inference="alignment:Splign:2.1.0"
     exon            752..959
                     /gene="Cbarp"
                     /gene_synonym="9630008F14; Dos; R29144/1"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1140
                     /gene="Cbarp"
                     /gene_synonym="9630008F14; Dos; R29144/1"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..2958
                     /gene="Cbarp"
                     /gene_synonym="9630008F14; Dos; R29144/1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctcaaaatg cagcccacgg ccaccatggc cacagcggcc gccactaccg ccactgttgc
       61 cctgacgact tcgtgggaca atgccaccag ccgccccacg gcggagcctg accccatctt
      121 ggacaactat gtgctgctgg tggtggtgat gtcgctgttc gttggaggca cgctggtggt
      181 gctgtctggc gttcttctgc tctgcaaacg ctgctgggag gtgcaccagc gcttcaacag
      241 ggccatggag gaagcagaga agaccaccac tacttatctg gacaacggca cccaccctat
      301 acaagacccc gactgcaggg gggaagaccc cgagggccag gacaccgaaa cagagcgctt
      361 cctagccacc agctccaccg gccgccgcgt gtccttcaac gaggctgccc tgtttgaaca
      421 gagccgcaag gctcaggaca agggccgccg gtacaccctg acagaagggg atttccatca
      481 cctcaagaat gcccgcctca cccacctcca cctaccgccc ctcaaaatcg ctactatcca
      541 tgagtgtgat tcgggggagg ccagtgcagc ggccacaccc cacccagcta ccacctccaa
      601 ggacagcttg gctattttcc agccccctgg gaaaaccctc accggccact cagtcggccc
      661 cagctccgcc ctgccaggag gtccctacaa ctccgtggac ttctcagaga tcagcccctc
      721 aacctccagt gactctgggg agggcatttc gttagatgca ggtacccggg gtgccaaggc
      781 tgctgggcct gaaacagtgc ctggggagat gggcacaggc tcctccgggt cgggcactgt
      841 tttgcaattc ttcactcggc tacgccgaca tgccagcctg gatggagcca gcccctactt
      901 caaggtcaag aaatggaagc tggagcccag ccagagagcg tccagtctgg acacgagagg
      961 ttcccctaag aggcaccact ttcagcggca gcgggcagcc agtgagagca tggagcagga
     1021 gggggacgtc ccccatgccg acttcattca gtacattgcc agcgcaggcg actcggtggc
     1081 cttcccaccc ccccgcccct ttctggccag ccccaccagc ccgcccccca ctctcggcag
     1141 gctagaggca gcagaggcgg cgggaggagc gagccctgag actcctccgg agcatggcat
     1201 cagtttgggg cccgagcatg cgcagcagca ggacccgcag caagagcagg acgccgagca
     1261 tgcacagtgc agctaccgtg acctgtggag ccttcgtgct tcgctcgagc tccatgcagc
     1321 cactgcatcg gaccacagca gcagcggcaa tgaccgcgac tcagtgcgca gcggcgatag
     1381 ctcgggctcg ggttccggag gtggaggggc agcacccgcc ttcccacccc ctccggagtc
     1441 tccacctgct ttgaggccta aggacggcga agcccgccgc ctgctacaga tggacagtgg
     1501 ctatgcgagc atcgaggggc gcggagcagg cgacgaagtt tcagaacttc ctgctccagc
     1561 ccgcagtcct ccccgcagcc cgcgagcctg gccacgcagg ccgcgccgcg attacagcat
     1621 cgacgagaag acggacgctc ttttccatga gttcctgcgc catgaccctc attttgacga
     1681 tgcaccgcgt caccgcacac gtgcacatcc tcacactcat gcgcggaagc aatggcaaca
     1741 gagaggacgg cagcacagcg accccggtgg tgcacgtgca gccacgcccc ctggagtggc
     1801 ccgccctaca cgtgcgccat tacgccgtgg ggacagcgtt gattgtcctc ctgaaggccg
     1861 tgcgctgccc atcacgggtg atgacccatc cattcctgtc atcgaggagg agcctggcgg
     1921 tggaggcggt ggttgcccag gctctgggtt gtgcgttgag cccgccgggg ccctgctaga
     1981 caagctagca gccagcctcg acgagagact cttctctccc cgtcttgctg agccagttgc
     2041 ctcatcccag gtgctgattg tcgctgctgc tgcccctaca tcccctgacc acagcccggc
     2101 ctaagctctg tactggacct gcctctctgc tgcttctccg gcagcacatg gggctgctgt
     2161 gggaatggtg gcaacagcgg gagcaacctg aggtggccgt gcatgggtac acggccccca
     2221 aatcccaagt gtgcacatat agtgtcccct gggcacttag cgcagtggcc tccggaagca
     2281 agaggctcca ggacccaggc tcaactgcag ggaggatgac gagactggac tctccggtcc
     2341 atatatggtt gaccccagca cccagcctct ggccacagat gctggtggag caggttctga
     2401 ggtgcatgtg cagcctccct ccaggatcag ctgaccctcc actcgtgagc actggcaggc
     2461 agtaacactg cctgccactg tgtgagcgaa cctactggag gtgaagtgac tgtggggcac
     2521 tgaggatcag agaggagctc gccgccccat attctgagtt gatttaccct gtccatggta
     2581 tgcgctctac ctttcctctc tgagcaataa ccgaccgcgc ctgctctctg catgtgcaca
     2641 ggctccccgt ctcattcctc cccgagagcc ttgggctttg gacacaacgg acagaacagc
     2701 ccaggtggca gcttcaagtt tcccaagctt tatttattgc caaaagatag ggcagactcg
     2761 ctgtgagtgc ctgcccactc cctgccctgc gccctctgtg gttggtcgtg ttgtctggtt
     2821 aatcataaat gtctctgcat atttgtttgc tctgggtttt ctctgcaggc caccctgtgc
     2881 cccgcctgct ccatatttcc aaacaccctc atagccatag ctcaaatcca cctgttttat
     2941 taaaaaaaaa gaaaccaaaa aaaaaaaaaa aaaaaaaa
//
