LOCUS       NM_028444               1026 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus caveolae associated 3 (Cavin3), mRNA.
ACCESSION   NM_028444
VERSION     NM_028444.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1026)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1026)
  AUTHORS   Ahuja,N., Hiltabidle,M.S., Rajasekhar,H., Voss,S., Lu,S.Z.,
            Barlow,H.R., Cowdin,M.A., Daniel,E., Vaddaraju,V., Anandakumar,T.,
            Black,E., Cleaver,O. and Maynard,C.
  TITLE     Endothelial Cyp26b1 restrains murine heart valve growth during
            development
  JOURNAL   Dev Biol 486, 81-95 (2022)
   PUBMED   35364055
REFERENCE   3  (bases 1 to 1026)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1026)
  AUTHORS   Park,P.J. and Kim,S.T.
  TITLE     Caveolae-Associated Protein 3 (Cavin-3) Influences Adipogenesis via
            TACE-Mediated Pref-1 Shedding
  JOURNAL   Int J Mol Sci 21 (14), 5000 (2020)
   PUBMED   32679831
  REMARK    GeneRIF: Caveolae-Associated Protein 3 (Cavin-3) Influences
            Adipogenesis via TACE-Mediated Pref-1 Shedding.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1026)
  AUTHORS   Zhu,B., Sward,K., Ekman,M., Uvelius,B. and Rippe,C.
  TITLE     Cavin-3 (PRKCDBP) deficiency reduces the density of caveolae in
            smooth muscle
  JOURNAL   Cell Tissue Res 368 (3), 591-602 (2017)
   PUBMED   28285351
  REMARK    GeneRIF: studies establish a role of cavin-3 in the formation of
            caveolae in vivo but also show that the physiological consequences
            of cavin-3 ablation are modest
REFERENCE   6  (bases 1 to 1026)
  AUTHORS   Hernandez,V.J., Weng,J., Ly,P., Pompey,S., Dong,H., Mishra,L.,
            Schwarz,M., Anderson,R.G. and Michaely,P.
  TITLE     Cavin-3 dictates the balance between ERK and Akt signaling
  JOURNAL   Elife 2, e00905 (2013)
   PUBMED   24069528
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 1026)
  AUTHORS   Ludwig,A., Howard,G., Mendoza-Topaz,C., Deerinck,T., Mackey,M.,
            Sandin,S., Ellisman,M.H. and Nichols,B.J.
  TITLE     Molecular composition and ultrastructure of the caveolar coat
            complex
  JOURNAL   PLoS Biol 11 (8), e1001640 (2013)
   PUBMED   24013648
REFERENCE   8  (bases 1 to 1026)
  AUTHORS   Hansen,C.G., Shvets,E., Howard,G., Riento,K. and Nichols,B.J.
  TITLE     Deletion of cavin genes reveals tissue-specific mechanisms for
            morphogenesis of endothelial caveolae
  JOURNAL   Nat Commun 4, 1831 (2013)
   PUBMED   23652019
  REMARK    GeneRIF: The roles of cavins 2 and 3 in caveolar morphogenesis in
            vivo, are reported.
REFERENCE   9  (bases 1 to 1026)
  AUTHORS   Schneider,K., Kocher,T., Andersin,T., Kurzchalia,T., Schibler,U.
            and Gatfield,D.
  TITLE     CAVIN-3 regulates circadian period length and PER:CRY protein
            abundance and interactions
  JOURNAL   EMBO Rep 13 (12), 1138-1144 (2012)
   PUBMED   23079727
REFERENCE   10 (bases 1 to 1026)
  AUTHORS   Izumi,Y., Hirata,M., Hasuwa,H., Iwamoto,R., Umata,T., Miyado,K.,
            Tamai,Y., Kurisaki,T., Sehara-Fujisawa,A., Ohno,S. and Mekada,E.
  TITLE     A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and
            PKCdelta are involved in TPA-induced ectodomain shedding of
            membrane-anchored heparin-binding EGF-like growth factor
  JOURNAL   EMBO J 17 (24), 7260-7272 (1998)
   PUBMED   9857183
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC009660.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC009660.1, BI408052.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1026              BC009660.1         1-1026
FEATURES             Location/Qualifiers
     source          1..1026
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 55.87 cM"
     gene            1..1026
                     /gene="Cavin3"
                     /gene_synonym="3110015B12Rik; 6330514M23Rik; Prkcdbp;
                     SRBC"
                     /note="caveolae associated 3"
                     /db_xref="GeneID:109042"
                     /db_xref="MGI:MGI:1923422"
     exon            1..422
                     /gene="Cavin3"
                     /gene_synonym="3110015B12Rik; 6330514M23Rik; Prkcdbp;
                     SRBC"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..821
                     /gene="Cavin3"
                     /gene_synonym="3110015B12Rik; 6330514M23Rik; Prkcdbp;
                     SRBC"
                     /note="serum deprivation response factor-related gene
                     product that binds to C-kinase; cavin-3; protein kinase C,
                     delta binding protein"
                     /codon_start=1
                     /product="caveolae-associated protein 3"
                     /protein_id="NP_082720.1"
                     /db_xref="CCDS:CCDS21652.1"
                     /db_xref="GeneID:109042"
                     /db_xref="MGI:MGI:1923422"
                     /translation="MGESALEPGPVPETPAGGPVHAVTVVTLLEKLATMLEALRERQG
                     GLAERQGGLAGSVRRIQSGLGALSRSHDTTSNTLTQLLAKAERVGSHADAAQERAVRR
                     AAQVQRLEANHGLLVARGKLHVLLFKEETEIPARAFQKVPELLGPEDQLVLGPDQPED
                     EVGESSEEEPVESRAQRLRRTGLQKVQSLKRALSSRKAAQPTPVKPPRVGPVRSSEGP
                     SEGQPAAQPEMESELETALEPEPPQPTKEDPEKPVLQIESAA"
     exon            423..1026
                     /gene="Cavin3"
                     /gene_synonym="3110015B12Rik; 6330514M23Rik; Prkcdbp;
                     SRBC"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atcggtctca gggagagcag gcccggtggt cagagatcat gggggagagc gcactggagc
       61 ccggacctgt gcctgagacg cccgcagggg gtccggtgca cgcagtcacc gtggtgacct
      121 tgctggagaa attggccacc atgctggagg ctctgcggga gcggcaaggc ggcctggctg
      181 agaggcaggg cggcctggcg ggctccgtgc gtcgcataca gagtggcctg ggtgcgctga
      241 gtcgcagcca cgacaccacc agcaacacac tgacgcagct gctggccaag gcggagcgcg
      301 tgggctcgca cgccgacgca gcccaggagc gggccgtgcg tcgcgctgct caggtgcagc
      361 ggttggaggc caaccacggg ctgctggtgg cgcgcgggaa gctgcacgtc ctgctcttca
      421 aggaggagac tgaaattcca gcccgcgcct tccagaaagt cccagagctc ttgggtccgg
      481 aggaccagtt ggtgctgggc ccagatcagc cagaggatga agttggagag agttctgaag
      541 aggagccagt ggagtccagg gctcagcggc tgcgccgcac tggtttacag aaagttcaaa
      601 gcctgaaaag ggctctttcc agtcgtaaag cagcacagcc cacaccagtc aagccgccac
      661 gcgtagggcc tgtccggagc tctgaaggcc catcagaagg ccagcctgca gctcagcctg
      721 aaatggagtc cgagctcgag actgccctgg agccagaacc tcctcaacct accaaggaag
      781 atcctgagaa acccgtgctt caaatagaga gcgcagcctg atccctgggg ctgcctgtcc
      841 cattcggtgc ttaagccttg tcccaaaata agtacttata gagtgcagca cttacatcca
      901 aataaggaga gaatcctgca tccactgccc agctccaaag cttccttcct ggctttccag
      961 tctgaaccct gtgtcctctg acagaggagc tttcagccta atttaggttc accaccaata
     1021 aaagca
//
