LOCUS       NM_001368822            3465 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus cation channel sperm associated auxiliary subunit
            epsilon 2 (Catspere2), transcript variant 3, mRNA.
ACCESSION   NM_001368822
VERSION     NM_001368822.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3465)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3465)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC113044.9, AC124621.18 and AC119928.8.
            
            Transcript Variant: This variant (3) encodes the longer isoform
            (a).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: downstream AUG is associated
                                                with N-terminal localization
                                                signal
            inferred exon combination        :: based on alignments, homology
            RefSeq Select criteria           :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-187               AC113044.9         123485-123671
            188-236             AC113044.9         135082-135130
            237-310             AC113044.9         147215-147288
            311-380             AC113044.9         148002-148071
            381-445             AC113044.9         149764-149828
            446-470             AC113044.9         172396-172420
            471-548             AC113044.9         179007-179084
            549-626             AC124621.18        112913-112990
            627-733             AC124621.18        132048-132154
            734-1226            AC124621.18        133842-134334
            1227-1704           AC124621.18        139082-139559
            1705-2159           AC124621.18        146606-147060
            2160-2218           AC124621.18        148572-148630
            2219-2294           AC124621.18        151656-151731
            2295-2347           AC124621.18        158218-158270
            2348-2398           AC124621.18        175835-175885
            2399-2432           AC124621.18        176867-176900
            2433-2512           AC124621.18        176969-177048
            2513-2612           AC119928.8         138923-139022       c
            2613-2699           AC119928.8         133357-133443       c
            2700-2857           AC119928.8         131104-131261       c
            2858-2911           AC119928.8         118018-118071       c
            2912-3465           AC119928.8         115200-115753       c
FEATURES             Location/Qualifiers
     source          1..3465
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 82.87 cM"
     gene            1..3465
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /note="cation channel sperm associated auxiliary subunit
                     epsilon 2"
                     /db_xref="GeneID:545391"
                     /db_xref="MGI:MGI:5589632"
     exon            1..187
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     CDS             120..3065
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /note="isoform a precursor is encoded by transcript
                     variant 3; catSperepsilon-like; catSper-epsilon-like;
                     cation channel sperm-associated protein subunit
                     epsilon-like protein; catsper channel auxiliary subunit
                     epsilon 2"
                     /codon_start=1
                     /product="cation channel sperm-associated protein subunit
                     epsilon-like protein isoform a precursor"
                     /protein_id="NP_001355751.1"
                     /db_xref="CCDS:CCDS87931.1"
                     /db_xref="GeneID:545391"
                     /db_xref="MGI:MGI:5589632"
                     /translation="MLARRVVAALLLWLSCCVSALWRYYINSQDYSIFSTRSSIKLEY
                     EGNSFVSWKIPESCKVENNTSPKTTLHCKRAGIHTIEPIARNQEVERHLTVDNSYICY
                     LWYFTVVDVYYNLSQIVTIWVYDPESASTEELIRTAKKPSLIVTIWVYDPESASTEEL
                     IWTAKKPSLNSLVLTKQMNTLGQRPFIFTVEKRLAYHPGPLTSEGTWVIHLPMSTDDI
                     AKVIQGNNVDFQDCRIADLHFLLTFPMEIVLEPPGYLPLTLPPGSPLMLSWDTCISTF
                     ALLATDQETFQTNDSFQTWTRVRAPPGILSDAQRHSLRDVLVFRTGILFLVETTVYLK
                     TDNEFIKLDKSRGISETGILGLSKRRWCQIRYLYKSAAGRTFVLAWTKSEVYGGFGKF
                     KFMRFTTTSRLKYLLKLPPTDTLEIITVEYSWHPLEAAALLSHCSVCTTTKNIRMVIF
                     NSAYFSWKLQDFELQVPKEAKLEYRFLYSAMPDIIVWDEHQVYYGYRNFAVFGTITTA
                     SGETNLSSLSQGSNIHQVLTDSIGNVVVKMENNVMFYIKADITEAVILHTWVNTTAKT
                     GLFFDKSFEVCILYYNENLDEKYQLQTQPYPLILELQSINKDLGDWCPYLAFQHNIHS
                     QFYHMDKGESLTIWSQIVYPENRGLYIVLEHYGMRILTWTQNIEYEIASGFCTKTLIT
                     RFFQTTNYELVDNYYQLQKENTGLLVFQFRPSEFSRMCPTAKPVFEIDVGCDSSKHIM
                     VQGFNRSGCQRRDFSYVIDKELLRESLSDNLKVRYDVAKYGCPLTLELGQMFQPIVEL
                     YDENGFIKIVDANFILWEIHGRNDYTFNSTMEQNGCINEAQTWDAMIEENPGIPLDDV
                     WGPQNYRPCFSYAIGKPGDLGQPYEILNYSNKNHIKWPMTYAGMYVYRLKILDPNYSF
                     CNLTTIFAIESLGMIPRSSVYLVAAFIFVLMLTFISILVLSYFWYSKIYRQFIIEPLH
                     KPPEKQKKN"
     exon            188..236
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            237..310
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            311..380
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            381..445
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            446..470
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            471..548
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            549..626
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            627..733
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            734..1226
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1704
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            1705..2159
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            2160..2218
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2294
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            2295..2347
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            2348..2398
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            2399..2432
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            2433..2512
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            2513..2612
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            2613..2699
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            2700..2857
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            2858..2911
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
     exon            2912..3465
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agttaagctc ttgttccctg cgcgtgccca gcatgcccag tgcagggcaa cggaagcctg
       61 ggagcttgct agccctgcag gccttgcaga agtggttgct tagaggagga gttggcgcca
      121 tgttagcccg gcgggtggtg gcggcgctgc tgttgtggct gagctgctgt gtctcagctc
      181 tgtggaggta ctacataaat agccaagact attccatttt tagtaccagg agttctatta
      241 aattagagta tgaaggaaac tcatttgtgt catggaaaat accagaaagc tgtaaagttg
      301 aaaacaatac atcacccaag acaacactac actgcaaaag ggctggaatt cacacgatag
      361 agccaattgc cagaaaccaa gaagtggaac ggcatctgac tgtggataat tcttatattt
      421 gctacttgtg gtatttcaca gttgtagacg tttattacaa cttaagccag attgtcacca
      481 tatgggtgta tgatccagaa agtgccagca ctgaagagct gataaggacc gcaaagaaac
      541 cttcactgat tgtcaccata tgggtgtatg atccagaaag tgccagcact gaagagctga
      601 tatggaccgc aaagaaacct tcactgaatt ccttggtact aaccaagcag atgaatacct
      661 tggggcagcg tcctttcata ttcacagttg agaagaggct cgcgtaccac ccaggtccct
      721 taacttcaga aggaacctgg gtcattcacc tgccaatgtc tacagatgat atagccaaag
      781 tgatacaagg taacaatgtg gatttccagg actgtcgcat tgcagatctc cacttcttac
      841 tgacctttcc catggagatt gtgttggagc ctcctggata tctgccactc accctgccac
      901 ctggaagtcc attgatgctt agctgggata cctgtatctc tacatttgct ctcttggcca
      961 ctgaccagga gacctttcaa acaaatgatt cctttcaaac ctggaccaga gtaagagccc
     1021 ctccaggtat cctgagtgat gctcaaaggc acagtctgag ggatgtgctc gtattcagaa
     1081 caggaattct gtttctagta gaaactactg tttacctaaa aacagacaat gaatttataa
     1141 aactggacaa aagcagaggt atttctgaaa ctggaattct tggcttgtca aaaagaagat
     1201 ggtgtcagat tagatattta tacaagagtg cagcaggacg aacttttgtg ttagcttgga
     1261 caaaaagtga agtttacggt ggatttggta aatttaaatt tatgagattc acaactactt
     1321 cacggctaaa atatcttcta aagctccctc ccactgacac cctggaaata attactgttg
     1381 agtattcatg gcatccgctg gaggctgctg ctttactgtc acactgctct gtctgcacca
     1441 ccaccaagaa cattcgcatg gtaatattta attctgcata tttttcgtgg aaactccagg
     1501 actttgaact acaagtgccc aaggaggcca agttagagta tcgctttctt tactctgcca
     1561 tgcctgatat tatcgtgtgg gacgaacacc aggtttacta tggctacaga aattttgctg
     1621 tttttggaac tataacaaca gcttcaggag agaccaatct gtcatcgtta tcacagggca
     1681 gcaacatcca ccaagtcctt acagatagta ttggaaatgt tgtggtaaaa atggaaaata
     1741 atgtaatgtt ctacatcaag gctgacatta cagaggcagt tatactacat acatgggtaa
     1801 acacgactgc aaagacaggg cttttcttcg acaaatcttt tgaagtatgt atattatact
     1861 ataatgaaaa tctcgacgag aaataccagt tgcagacaca gccatatccc ttaattctgg
     1921 agttacaaag tataaataaa gatttaggag actggtgccc atatctggca tttcagcaca
     1981 atattcatag tcagttttac catatggata aaggagaaag cctgacaatt tggagtcaaa
     2041 tagtgtaccc agaaaatcgg ggtctctaca ttgttctgga acactatggc atgcgtatac
     2101 tgacctggac acaaaacatt gagtatgaga ttgcatcagg attctgtact aaaactttga
     2161 taacaagatt ttttcagaca acaaattatg aattagtgga taattattat cagttacaaa
     2221 aagagaacac aggtctcctg gtttttcagt tccgacctag tgaattttca agaatgtgtc
     2281 caacagccaa accggtgttc gaaatcgatg ttggctgcga ttcaagtaaa cacattatgg
     2341 ttcaaggatt taataggagt ggatgtcaac gtcgagattt ctcttatgtg atcgacaagg
     2401 aacttctgag agaaagtcta tctgacaatt tgaaagtaag gtacgacgtg gcaaaatatg
     2461 gctgccctct cacccttgaa ttgggacaaa tgtttcaacc catagtagaa ttgtatgatg
     2521 aaaatggatt tattaaaata gttgacgcaa attttatctt gtgggaaatc catggcagga
     2581 atgactacac ctttaattct acgatggagc agaatggttg tataaatgaa gcacagacgt
     2641 gggacgcgat gatagaggaa aaccctggca tcccactgga tgatgtctgg gggcctcaga
     2701 actataggcc ttgtttttct tatgctattg ggaagccagg agacctaggc caaccatatg
     2761 agattctaaa ctattctaat aaaaaccaca taaaatggcc catgacgtat gctggaatgt
     2821 atgtgtatcg cttgaagatc ttggatccaa actatagctt ctgtaaccta acaactattt
     2881 ttgcgattga gagcttagga atgattccca gatcaagtgt ctacctggta gctgccttca
     2941 tttttgtcct gatgctcaca ttcatcagca ttctagttct gagctacttc tggtactcga
     3001 agatttacag gcagttcatt attgagccac ttcacaagcc tcctgaaaaa cagaagaaaa
     3061 attaggaaac tggagattaa ctctgaatac atatatgtat ttagataata tacatttaag
     3121 taattatatt aagaatgtat acttgcctaa gaagcattaa atataagctc atattattat
     3181 taaattcgat atctgaaaaa tattgttaca ttactccccc aaatagctag catacattgt
     3241 attattgtgt ttgttattcc attttaatgg tagcatatat actcttacat ttgaatttaa
     3301 aaaaccataa aaaaacatcc agttaccttt ggctctgctt cctaacaatg aaagtttttg
     3361 acagagaata aatgtgtcaa gtattatttt attggatcat atggaactgt ttattattgt
     3421 ggttaattta tatataagaa ctcaataaaa gcatatgtat ttagt
//
