LOCUS       NP_001355751             981 aa            linear   ROD 02-MAY-2024
DEFINITION  cation channel sperm-associated protein subunit epsilon-like
            protein isoform a precursor [Mus musculus].
ACCESSION   NP_001355751
VERSION     NP_001355751.1
DBSOURCE    REFSEQ: accession NM_001368822.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 981)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 981)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC113044.9, AC124621.18 and AC119928.8.
            
            Transcript Variant: This variant (3) encodes the longer isoform
            (a).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: downstream AUG is associated
                                                with N-terminal localization
                                                signal
            inferred exon combination        :: based on alignments, homology
            RefSeq Select criteria           :: based on conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..981
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 82.87 cM"
     Protein         1..981
                     /product="cation channel sperm-associated protein subunit
                     epsilon-like protein isoform a precursor"
                     /note="catSperepsilon-like; catSper-epsilon-like; cation
                     channel sperm-associated protein subunit epsilon-like
                     protein; catsper channel auxiliary subunit epsilon 2"
                     /calculated_mol_wt=111455
     sig_peptide     1..20
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2176
     Site            62
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (A0A0A6YXX9.1)"
     Site            114
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (A0A0A6YXX9.1)"
     Region          <729..980
                     /region_name="CATSPERD"
                     /note="Cation channel sperm-associated protein subunit
                     delta; pfam15020"
                     /db_xref="CDD:464451"
     CDS             1..981
                     /gene="Catspere2"
                     /gene_synonym="Gm16432; Gm30473"
                     /coded_by="NM_001368822.1:120..3065"
                     /note="isoform a precursor is encoded by transcript
                     variant 3"
                     /db_xref="CCDS:CCDS87931.1"
                     /db_xref="GeneID:545391"
                     /db_xref="MGI:MGI:5589632"
ORIGIN      
        1 mlarrvvaal llwlsccvsa lwryyinsqd ysifstrssi kleyegnsfv swkipesckv
       61 enntspkttl hckragihti epiarnqeve rhltvdnsyi cylwyftvvd vyynlsqivt
      121 iwvydpesas teelirtakk pslivtiwvy dpesasteel iwtakkpsln slvltkqmnt
      181 lgqrpfiftv ekrlayhpgp ltsegtwvih lpmstddiak viqgnnvdfq dcriadlhfl
      241 ltfpmeivle ppgylpltlp pgsplmlswd tcistfalla tdqetfqtnd sfqtwtrvra
      301 ppgilsdaqr hslrdvlvfr tgilflvett vylktdnefi kldksrgise tgilglskrr
      361 wcqirylyks aagrtfvlaw tksevyggfg kfkfmrfttt srlkyllklp ptdtleiitv
      421 eyswhpleaa allshcsvct ttknirmvif nsayfswklq dfelqvpkea kleyrflysa
      481 mpdiivwdeh qvyygyrnfa vfgtittasg etnlsslsqg snihqvltds ignvvvkmen
      541 nvmfyikadi teavilhtwv nttaktglff dksfevcily ynenldekyq lqtqpyplil
      601 elqsinkdlg dwcpylafqh nihsqfyhmd kgesltiwsq ivypenrgly ivlehygmri
      661 ltwtqnieye iasgfctktl itrffqttny elvdnyyqlq kentgllvfq frpsefsrmc
      721 ptakpvfeid vgcdsskhim vqgfnrsgcq rrdfsyvidk ellreslsdn lkvrydvaky
      781 gcpltlelgq mfqpivelyd engfikivda nfilweihgr ndytfnstme qngcineaqt
      841 wdamieenpg iplddvwgpq nyrpcfsyai gkpgdlgqpy eilnysnknh ikwpmtyagm
      901 yvyrlkildp nysfcnltti faieslgmip rssvylvaaf ifvlmltfis ilvlsyfwys
      961 kiyrqfiiep lhkppekqkk n
//
