LOCUS       NM_173023               3716 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus cation channel sperm associated auxiliary subunit beta
            (Catsperb), mRNA.
ACCESSION   NM_173023 XM_909248
VERSION     NM_173023.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3716)
  AUTHORS   Lin,S., Ke,M., Zhang,Y., Yan,Z. and Wu,J.
  TITLE     Structure of a mammalian sperm cation channel complex
  JOURNAL   Nature 595 (7869), 746-750 (2021)
   PUBMED   34225353
REFERENCE   2  (bases 1 to 3716)
  AUTHORS   Chung,J.J., Navarro,B., Krapivinsky,G., Krapivinsky,L. and
            Clapham,D.E.
  TITLE     A novel gene required for male fertility and functional CATSPER
            channel formation in spermatozoa
  JOURNAL   Nat Commun 2, 153 (2011)
   PUBMED   21224844
REFERENCE   3  (bases 1 to 3716)
  AUTHORS   Turner,L.M., Chuong,E.B. and Hoekstra,H.E.
  TITLE     Comparative analysis of testis protein evolution in rodents
  JOURNAL   Genetics 179 (4), 2075-2089 (2008)
   PUBMED   18689890
REFERENCE   4  (bases 1 to 3716)
  AUTHORS   Liu,J., Xia,J., Cho,K.H., Clapham,D.E. and Ren,D.
  TITLE     CatSperbeta, a novel transmembrane protein in the CatSper channel
            complex
  JOURNAL   J Biol Chem 282 (26), 18945-18952 (2007)
   PUBMED   17478420
  REMARK    GeneRIF: CatSperbeta protein is absent in CatSper1(-/-) sperm,
            suggesting that it is required for trafficking or formation of a
            stable channel complex
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK029843.1 and AK030010.1.
            
            On Sep 12, 2009 this sequence version replaced NM_173023.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029843.1, AK030010.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1974              AK029843.1         2-1975
            1975-2493           AK030010.1         1966-2484
            2494-2757           AK029843.1         2495-2758
            2758-3155           AK030010.1         2749-3146
            3156-3220           AK029843.1         3158-3222
            3221-3655           AK030010.1         3212-3646
            3656-3716           AK029843.1         3659-3719
FEATURES             Location/Qualifiers
     source          1..3716
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 51.23 cM"
     gene            1..3716
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /note="cation channel sperm associated auxiliary subunit
                     beta"
                     /db_xref="GeneID:271036"
                     /db_xref="MGI:MGI:2443988"
     exon            1..119
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            120..198
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            199..287
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            288..428
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            429..489
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            490..585
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            586..735
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            736..831
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            832..950
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            951..983
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1050
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1097
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1247
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1248..1406
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1407..1551
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1552..1706
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..1861
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1862..2055
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2056..2385
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2386..2525
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2526..2723
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2724..2834
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2835..2945
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2946..3081
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3082..3182
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3183..3257
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3258..3716
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3504..3509
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3526
                     /gene="Catsperb"
                     /gene_synonym="4931410B03; 4932415G16Rik"
                     /note="major polyA site"
ORIGIN      
        1 gaaaactcag ctcttgatac ttgggtcttc aatctgtaga gaagaaacaa ggctaaggta
       61 gaaacaaaca acaacacaaa gccaaaaaga aaggcaccga ggaagacatt caattaaaga
      121 tggagtcacc acttatatat gttatgctgg tgcttttgaa tgtatttgta ttttcatcag
      181 gagtaataca taataagggt aaggagcgaa cttacttttc ttgttccggt gaagggattc
      241 tcacaggtct gcatacaatc aagttgttcc ttaccatgga caatttgaaa gtccgctgtt
      301 tcttcagaaa tgaaaatcaa agtccttcaa aggaaatttt gggtctcttt acatcaggag
      361 gccttgctcc caacatgata attacgaaca gtacattcta cggtggctac tattttaaat
      421 taactccgtt cagtaatcgt cttgagtggt taattgatat tcctagacaa aacatcactg
      481 taaacacaga cattgcagct gtagaacagt ggatgataaa gatcacaatg catgaaggat
      541 taaacattta tgatactgag gggaccttat tggatcttgt tcgagagcct attcttcagt
      601 ggaatcttgg acgtgtgctt acagaaatgg aggttagaga tttatatcca gaagtgaacg
      661 atatcaaagt gacaaagagc ccctgtgcca atgatgtggc tttaataggc tttatgatga
      721 aaccatcatc taatggtgtt ttcataggaa aaaccatttc tggattttgg acctataagg
      781 aatgcatatg gcatgacctc acagagataa tctatgcaga acttaaagat gaacaccaag
      841 gactcacagt gatagatctg gttttaacaa atcatttttt agtcatcctt acctctttgg
      901 gtctttatgt aagtagtgat cttcgttatc caaccacttc acagataaag ctttccagag
      961 cagagttttg tggatttgaa agggttgact atattagagg aaatctgtgg tataatgaaa
     1021 aatgttttgc aaacagagaa agttttgaag ttgattatgt tactatcact ttcaacagaa
     1081 acaggaccct cagtgagtcc agttcttgtt ttttcagtaa agaaccattt cttcactggt
     1141 taccttgtgt attctctact attaaaaatg aaaaatccat tccgcgtgtg ataacattcc
     1201 ttattgacca agaaacagac agtggaattt atcttttcaa tgtgcaagat accaaagaga
     1261 cctatgtcac tgtagctatg ctcaaggatg ggaaaccaag ccctcgacca aaatttccta
     1321 gttttcattt tccttcaaca ttcactcttc cacttggaat gatattccat cccagaagcc
     1381 actttctgta tgtttatggc agtcaaatat gggtttcaat ggatggtggc aatacttttg
     1441 aaatgctgtg taacttattc tcacaccatg taacaaagac ttctaatagc ttttatactt
     1501 cagatattgt ttttattgta gaagatggaa gaattttgac gaccaaggca ggcttaacta
     1561 catatagtga actggggata ttaaaggatg ccattttcac attgtactat gatcaattgg
     1621 gatacataca caaactgacg ccagaaaact ttgacgctgg ttcaaaactt ttagggcatg
     1681 gaaattctgg cagcattttt ggaaagaggc ctgatttggg atttgaagct atactagttc
     1741 cacaatatat ctctaccaac gaaatgtatt tctttgcaca tgtacctctg actatgccta
     1801 ccaacataca gtggaaaaag agatttaaaa ctattcacct ggggaaaaca atagagttca
     1861 gtaaaactgg acttgctaat atcaaaaatg tatatatgca taaaactgag cctgtgggat
     1921 ttcagacatc tattcacaca gaaataatag tccctttcgg gattgagaac tcaaaggaca
     1981 gcccttgttt acttagcgat cttgaaatta catattctgg aaagttatac tacacaatta
     2041 agcttctatc aaaaaatccc ctgcatgagc ttaaatctac agatgtagaa aagtctgtgt
     2101 taatacctgg ctatagcagc ttcctgatca tgaacattac agataaatgg actgcttctg
     2161 ccttggctac tatgcctcaa gcaataaaat caaacctgaa gtttctaaca ggttcttggt
     2221 tcttatacaa ctttggcacg gctggaggac ggaaatggag cataagtaca agacaatgta
     2281 attattggat tcaacaagat agtcttgatt ttatgtccct taatcttgtg aagtatattg
     2341 atgtgggaaa cacaatagat tttcaattta agattattcc aaaagctatg tcaacatttc
     2401 ctatccctcc agtcagtatg gtggttggaa acccaggatt ggtggaagtt aagacacaag
     2461 gtgtttttga cctcaatgaa aattattatc tagatattca tgtatctgga agattttttc
     2521 aaaaaggttc cacttcaata gcactggttc tttgggaggg atcaagtaaa tgctatgcta
     2581 ttacactgct gccaaccata aagagcagct gcagttacct caggactatg caccacactc
     2641 ctggcaggca cataccacct gaagactgga ttagcggagt tcacaaggac agtcagggtt
     2701 tcaatatgat caaaactctg ccgataaact acagacctcc atcccacatg ggaatttcta
     2761 ttccactcac agataatttt tatcatgcag accctagcaa acccataccg agaaatcaat
     2821 ttcacaagtc aaaggaaact ggcaaataca aacagtgtgc taatgttacc agtcgggcaa
     2881 tgtgcaactg ctcagaacat caaaagtttt cccatgctgt tgctttctca gattgcaaag
     2941 aaaaggttca tcgtttcaag tttccagtca cacaataccc agttgttttg gaaattttca
     3001 atgaaagaga caaaatctcc gcagaacctc cgtatttagt taccatgact gaagtgaata
     3061 tgaggaaaaa ctggcaacta aaacacaatg agccagaaaa cgttaagaaa atgaagcatt
     3121 acttagagcc actgcttaag actccagtgt ataatccttt aggtctcaac ctaaccatac
     3181 agggctctga actgtttcac ttcaaggtgt ctgtggttcc tggagtcagc ttttgtgagt
     3241 taagtgaaga atttcagatt tatgtcgacg aagtcccatt gccttttcca ggacatgcac
     3301 taatagctgt tgcaacatct gtagtgctag gagtattaat ttttatagca tttgtattcc
     3361 aactgcgtaa catccaccca ctgaaggcat tgaagaaatc tattagggga aatcctggac
     3421 tcacctcaag tacaactgtt agctcataat ttaagtctgt ataattaacc aatgataact
     3481 gattatcttt gaatcctagt tccattaaac atgttcatat aacatactta aatttcttaa
     3541 atgtgcattt ggtacaatgc tatattatta ttatactatt ataattctag tttctgacag
     3601 tcagtagctt cacattacat tttcttattt ttaaaataca taaaagattg ttttaacact
     3661 tacatggcat gggtgttttg gggggagatt gttttccaaa atataaagtg ataacc
//
