LOCUS       NM_027937               6190 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus CASK interacting protein 1 (Caskin1), transcript
            variant 1, mRNA.
ACCESSION   NM_027937 XM_196170
VERSION     NM_027937.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6190)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6190)
  AUTHORS   Pulcrano,S., De Gregorio,R., De Sanctis,C., Volpicelli,F.,
            Piscitelli,R.M., Speranza,L., Perrone-Capano,C., di Porzio,U.,
            Caiazzo,M., Martini,A., Giacomet,C., Medina,D., Awatramani,R.,
            Viggiano,D., Federici,M., Mercuri,N.B., Guatteo,E. and
            Bellenchi,G.C.
  TITLE     miR-218 Promotes Dopaminergic Differentiation and Controls Neuron
            Excitability and Neurotransmitter Release through the Regulation of
            a Synaptic-Related Genes Network
  JOURNAL   J Neurosci 43 (48), 8104-8125 (2023)
   PUBMED   37816598
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6190)
  AUTHORS   Bencsik,N., Pusztai,S., Borbely,S., Fekete,A., Dulk,M., Kis,V.,
            Pesti,S., Vas,V., Szucs,A., Buday,L. and Schlett,K.
  TITLE     Dendritic spine morphology and memory formation depend on
            postsynaptic Caskin proteins
  JOURNAL   Sci Rep 9 (1), 16843 (2019)
   PUBMED   31727973
  REMARK    GeneRIF: Dendritic spine morphology and memory formation depend on
            postsynaptic Caskin proteins.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6190)
  AUTHORS   Katano,T., Takao,K., Abe,M., Yamazaki,M., Watanabe,M., Miyakawa,T.,
            Sakimura,K. and Ito,S.
  TITLE     Distribution of Caskin1 protein and phenotypic characterization of
            its knockout mice using a comprehensive behavioral test battery
  JOURNAL   Mol Brain 11 (1), 63 (2018)
   PUBMED   30359304
  REMARK    GeneRIF: Caskin1 contributes to a wide spectrum of behavioral
            phenotypes.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6190)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   6  (bases 1 to 6190)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   7  (bases 1 to 6190)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   8  (bases 1 to 6190)
  AUTHORS   Trinidad,J.C., Specht,C.G., Thalhammer,A., Schoepfer,R. and
            Burlingame,A.L.
  TITLE     Comprehensive identification of phosphorylation sites in
            postsynaptic density preparations
  JOURNAL   Mol Cell Proteomics 5 (5), 914-922 (2006)
   PUBMED   16452087
REFERENCE   9  (bases 1 to 6190)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ127019.1, BC060720.1 and BC059916.1.
            
            On Nov 28, 2007 this sequence version replaced NM_027937.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849379 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-296               CJ127019.1         187-482
            297-4034            BC060720.1         61-3798
            4035-5938           BC059916.1         2862-4765
            5939-6190           BC060720.1         5526-5777
FEATURES             Location/Qualifiers
     source          1..6190
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.4 cM"
     gene            1..6190
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /note="CASK interacting protein 1"
                     /db_xref="GeneID:268932"
                     /db_xref="MGI:MGI:2442952"
     exon            1..281
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     CDS             188..4483
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /note="isoform 1 is encoded by transcript variant 1;
                     caskin-1"
                     /codon_start=1
                     /product="caskin-1 isoform 1"
                     /protein_id="NP_082213.2"
                     /db_xref="CCDS:CCDS50013.1"
                     /db_xref="GeneID:268932"
                     /db_xref="MGI:MGI:2442952"
                     /translation="MGKEQELVQAVKAEDVGTAQRLLQRPRPGKAKLLGSTKKINVNF
                     QDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVL
                     KAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGR
                     VGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQ
                     TKSGTALHEAALCGKTEVVRLLLDSGINAQVRNTYSQTALDIVHQFTTSQASKEIKQL
                     LREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRV
                     GYFPSSLGEAIVKRAGSRTGSEPSPPQGGGSLGPSAPPEEIWVLRKPFAGGDRSGSLS
                     NVAGGRSTGGHALHAGSEGVKLLATVLSQKSVSESSPGDSPVKPPEGSSGAARSQPPA
                     AHAGQVYGEQPPKKLESASASASEGKSAEAVSQWLATFQLQLYAPNFTSAGYDLPTIS
                     RMTPEDLTAIGVTKPGHRKKITAEISGLNIPDWLPEHKPANLAVWLSMIGLAQYYKVL
                     VDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRKLAELQKAEYSKYEGGPLRR
                     KTPQSLEMMAIESPPPSEPAAAECQSPKMTTFQDSELSGELQAALSGPAEAGAAAVEK
                     SSNHLPPTPRTTSRESSLSGRARHISSSQELLGDGPPGPGSPMSRSQEYLLDEGMAPG
                     TPPKEVRSSRHGHSVKRASVPPVPGKPRQVLPSGASHFTPPQTPTKAQPGSPQALGGP
                     HGPATAKVKPTPQLLPPTDRPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPPAPGPAPP
                     PVPAAVPTLCLPPETDVEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQR
                     RVGRSHSVRAPAGTDKNVNRSQSFAVRPRKKGPPPPPPKRSSSAMASANLADEPAPDV
                     EAEDGRLGVRAQRRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAIRRPPEGHP
                     TPRPASPEPGRVATVLASVKHKEAIGPDGEVVNRRRTLSGPVTGLLATARRGSGEPAE
                     QSHFMEDGTARQRLRGPAKGEASAEGPPLARVEASATLKRRIRAKQSQQENVKFILTE
                     SDTVKRRPKAKEPDTGPEPPPPLSVYQNGTATVRRRPTSEQAGPPELPPPPPPAEPPP
                     ADLMQLPPLPLPDGNARKPVKPPVSPKPILSQPVSKIQGSPTPASKKVPLPGPGSPEV
                     KRAHGTPPPVSPKPPPPPTAPKPAKALAGLQSSSATPSPVPSPARQPPAALIKPASSP
                     PSQSASPVKPPSPGTPALHVPAKPPRAAASVVSGPPVASDCASPGDSARQKLEETSAC
                     LAAALQAVEEKIRQEDGQGPRPSSIEEKSTGSILEDIGSMFDDLADQLDAMLE"
     exon            282..333
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            334..431
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            432..577
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            578..673
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            674..804
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            805..913
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            914..1022
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1117
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            1118..1235
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1337
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..1426
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1511
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            1512..1615
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1726
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            1727..1828
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            1829..1967
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            1968..3968
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            3969..4383
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     exon            4384..6176
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5919..5924
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /note="hexamer: AATAAA"
     polyA_site      5938
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /note="major polyA site"
     regulatory      6152..6157
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
                     /note="hexamer: AATAAA"
     polyA_site      6176
                     /gene="Caskin1"
                     /gene_synonym="3300002N10Rik; C130061I24; C630036E02Rik;
                     mKIAA1306"
ORIGIN      
        1 cagttcgagc ccgaaacccc agcccgagcc cgagtccgag cccgagcccg aacccacgga
       61 gggcgctggg cggcgggcgg cgcagggagc gcgggctgga aaggatgcga tcgcagacgc
      121 ggagccgctg ctgcgtctga gccgccgaga gcaccaagcg ccgcgtcgct gcgggcccgg
      181 cggcgccatg gggaaggagc aggagctggt gcaggcagtg aaggcggagg acgtggggac
      241 cgcgcagagg ctgctgcaga ggccgcggcc ggggaaggcc aagctcctgg gctctaccaa
      301 gaagatcaat gtcaacttcc aggacccgga tggcttctca gccctgcacc atgccgccct
      361 gaatggcaac acagaattga tctctctgct gctggaggct caggctgctg tagacatcaa
      421 ggacaacaaa ggtatgcggc cgttgcacta cgccgcctgg cagggccgga aggagcccat
      481 gaagctggtg ctgaaggcag gctcagcagt aaatgtccca tccgacgaag gccacatacc
      541 cctgcatttg gctgcccagc atggtcacta cgatgtgtca gagatgctac tgcagcatca
      601 gtccaacccc tgtatggtag acaactctgg aaagacacct ctggacctgg cctgtgagtt
      661 cggccgcgta ggggtggtcc agctgctgct aagtagcaac atgtgtgcag ccttgctgga
      721 gccccgacca ggggacacca ccgaccccaa cggcaccagc cccctgcacc tggcagccaa
      781 gaatggccac atcgacatca tcaggctcct tcttcaggcc ggcatcgaca ttaaccgcca
      841 gaccaagtct ggcacagctc ttcatgaggc cgcactctgt gggaaaacag aagtggttcg
      901 gctactgttg gatagtggga tcaatgccca ggtgaggaac acctacagcc agacagcact
      961 ggacattgta caccaattta caacgtccca ggccagcaag gagatcaagc aactgcttcg
     1021 agaggcctca gcggctctgc aggtccgggc aacaaaggat tactgtaaca actatgatct
     1081 gaccagtctc aatgtgaagg ctggggacat tatcacggta cttgaacagc atccagatgg
     1141 ccggtggaaa ggctgtattc atgacaaccg gacaggcaat gacagggtgg gctacttccc
     1201 atcttccctg ggggaggcta ttgtcaagcg agcaggttcc cggacaggca gtgagccaag
     1261 cccaccccag ggaggtggct cactgggtcc ctctgcaccc ccggaggaga tctgggtgct
     1321 gaggaagcct tttgcaggtg gagatcgcag tggcagcttg agcaatgtgg ccgggggcag
     1381 gagtactggg ggccatgcct tgcatgcagg ctctgaagga gttaagctcc tggcaaccgt
     1441 gctttcccag aagtcagtct ctgagtccag cccaggagat agcccggtca agcctccaga
     1501 gggctcttca ggtgcggccc ggtcccagcc tccagcagcc catgctgggc aggtatatgg
     1561 ggagcagcca ccgaagaagc tggaatcggc ctcagcctcg gcctctgagg gcaagagtgc
     1621 tgaggcggtc agtcagtggc ttgccacatt ccagctacag ctctatgccc ccaacttcac
     1681 cagtgctggc tatgacctgc ccaccatcag tcgtatgacc cctgaggacc tcacagccat
     1741 tggcgttacc aagccaggcc accgtaagaa gattacggca gagatcagcg gcctgaacat
     1801 ccctgactgg ctgcctgaac acaaacccgc taacctggct gtgtggctgt caatgattgg
     1861 tctggcccag tattacaagg tgctggtgga caacggctat gagaacattg atttcatcac
     1921 cgatatcacc tgggaggacc tgcaggagat cggtatcacc aagctgggac accaaaagaa
     1981 gctgatgctg gcagtgagga aactggcaga gctgcaaaag gcagaatact ccaagtatga
     2041 ggggggaccc ctgcgccgaa agacacccca atcacttgaa atgatggcta ttgagtcacc
     2101 gcccccatct gagcctgctg cagcagagtg ccagtctccc aagatgacca ccttccagga
     2161 cagtgaactc agtggagagc tgcaagctgc cctgtctggc ccagctgaag caggtgcagc
     2221 tgctgttgag aaatcctcca accacctgcc acccactccg aggacaacct ctcgggagtc
     2281 cagcctgagt ggacgggctc ggcacataag cagctctcag gagctgttgg gcgatgggcc
     2341 tccagggcct ggcagtccta tgtcacgaag tcaggaatac ctgctggatg aggggatggc
     2401 tcctggcacc ccacccaagg aggtgcggtc cagccgccat ggccacagcg tcaagagggc
     2461 cagtgtgccc ccggtgcccg gcaagccacg acaggtcctt ccgtctggtg ccagccactt
     2521 cacaccccca cagacgccca ccaaagctca gccaggctcc cctcaggccc ttgggggacc
     2581 tcatggtcca gccacagcca aggtgaagcc caccccacag ctgctaccac caacagaccg
     2641 gcccatgtca ccccgttcct tgcctcagtc acccacacac cgtggctttg cctatgtgct
     2701 gcctcagcca gttgagggcg aggtagggcc acctgctccc ggacctgcgc ccccaccagt
     2761 acccgcagct gtacctactc tatgcttgcc cccagaaact gatgtagagc ctgggaggcc
     2821 caagaaacgt gcccacagct tgaatcgcta tgcagcatcc gacagtgagc ctgagaggga
     2881 tgagctgctg gtgccggctg ccgctggacc ctatgccaca gtccagaggc gtgtgggtcg
     2941 gagccattca gtgagggctc ctgctggcac ggacaagaat gttaaccgca gtcagtcctt
     3001 tgctgtgcgg ccacgtaaga aggggccccc accacctcca cccaaacgct ccagctcggc
     3061 catggccagt gccaacctag ccgacgagcc ggctccagac gttgaggcag aggacggccg
     3121 gctaggggtc cgggcgcaac gccgtcgggc tagtgatctc gccggcagtg tggacacagg
     3181 tagtgctggc agtgtgaaga gcatcgcagc catgttggag ctgtcttcca ttgggggtgg
     3241 agggcgggct attcgcaggc cccccgaagg ccaccccaca ccccgtcccg ccagtccaga
     3301 accgggccga gtagctaccg tgttggcctc tgtgaagcac aaagaggcca ttgggcctga
     3361 cggtgaagtg gtgaaccggc gccgtacact cagtggccca gtcactgggc ttttggccac
     3421 tgctcgccgg gggtctgggg aacctgcaga gcagagtcat tttatggagg atggcacagc
     3481 ccgacaacgg cttcgaggtc cagctaaggg tgaggcaagt gcggagggtc ctccccttgc
     3541 ccgggtagag gccagtgcca cgctcaagag gcgcatccgg gccaagcaga gccaacaaga
     3601 gaacgtcaaa ttcatcctga cagagtctga cacagtgaag cgcaggccta aggctaagga
     3661 gcctgacact ggccctgagc cacccccacc actgtctgtg tatcagaatg gcacagccac
     3721 cgttcgccga aggccaacct cagagcaggc tgggcctcca gagctgcccc ctcctccccc
     3781 tcctgctgag cccccacccg ctgacctgat gcagctgcct ccactgcccc tgcctgatgg
     3841 caatgcacgg aagcctgtga agccacccgt ctctcccaag cccattctgt ctcagcctgt
     3901 gtccaagatc cagggctcac ctacacctgc ctccaagaag gtgccactgc caggccctgg
     3961 cagcccagag gtaaagcgtg ctcatggcac gccaccgccc gtgtcaccca agccgcctcc
     4021 gccacctaca gcacccaagc cagccaaggc tttggcggga ctacagtcca gcagcgccac
     4081 cccctcgcct gtgccctctc cagcgcgtca gccgccagca gcgctcatca agccagctag
     4141 ttcgccgccc tcgcagagcg ccagccctgt caagccccct tccccaggga cacccgcgct
     4201 gcacgtaccc gccaagcccc ctcgcgctgc tgcttcagtg gtctccggac ccccagtagc
     4261 ttcagattgt gcttcacccg gggacagcgc tcggcagaag ctggaagaga ctagcgcgtg
     4321 tttggctgca gcactgcagg cagtggagga gaagataagg caggaagatg gacaaggccc
     4381 tcgcccctcc tccatcgagg agaagagcac tggcagcatc ctggaagaca tcggcagcat
     4441 gttcgacgac ctggccgacc agctggacgc catgctggag tgaggcagcc acccacgtgg
     4501 gcccacccgt actccccgca ctttgacctt tacctcagga cgggcacctt caagcggtgg
     4561 gtgggggccg agtgggcggg gcacgcccag ctctgcacaa gcacaactcc tactcctggc
     4621 ccaggctagt cgtcagtccc ctggcatggg ggtcaggggg cgctccaagg gctctgagca
     4681 gatgcgctgc ccgctggtgc ccattcctgt ctgctgctcc ctgtgcaaca actgctgggc
     4741 cctgctcttg caggctttgc tctgctggtg gagggttgcc cctcccttgc cctaggcaga
     4801 ctgagtgcca agggaagatg aggggggtgg ccactgtggc cctctttcca atctgtggca
     4861 gagcacaggc ctatgcccag cacagaactg cccattgggg aacctctgcc agccgctctg
     4921 gcacagcaca agggacaggg gggccaaggt tgggctcgcc ccactgcacc ccagaatata
     4981 agctatcaag agtattaatt tattgggaat gagctgaggc agatttcccc agaaaaacaa
     5041 aaagataact ttaacaaata tatatttaaa gagaagaaat attattgatt ctatagaaac
     5101 catttaccaa tgggaaggtt acaagtccag cttgagacta aagctgtcag aggctgaggc
     5161 cacctgtctg cccttctctt tcatctagga gtggccttgc ccttggtcac gagcacacac
     5221 agctgggagg cacagtctgg gagggtagct ctgcccgggg cctctgccca gggcctcccc
     5281 tctgttcttc cagcttccga gaggccgaag gacgtgaagg atgtgccttg ctcttactgg
     5341 ctctcctcca tgccacacag ggctggggag ggcttcttcc ttctgggtgt ggccatgccc
     5401 ttggggtgct ggtgtgaggg tgcacccagt gtgaacccta tgtgaactcg ggcatgagtg
     5461 caaaggcgtg catgccagcc taggggcagg ggtgtttgag gctgtgtctg ccctgcctcc
     5521 ccgaggcagc ctctgttggc agccatcccg cccatcttta attcccatgg atgttctgct
     5581 catggtctga ggctatgttg tgtagttcgt ctcacctttt cctccctcca aaaaatactg
     5641 actgctctcc tctctcgtgt ttgctgatcc acaagtgtcg ggcataacac tggcatttct
     5701 ttacctcccc ccctcaaaaa gaaacaaacc ccaaacaaaa ccgtaattgt ggtggagggc
     5761 agctaagagt gtggccacgg ggcccttgca gctgtcactc ctggcgcttc ctcatctgaa
     5821 catgctgacc gctcatcagc ctcctctgtg tgggccgccc aggctagggc tctaggaagt
     5881 ggggaggggg tctggacagg gagctgctgt cagctgtcaa taaacagcag aaaacagagc
     5941 tgcttggctc acactctttg ggggtgtggg ggggaggggg gtaatggagc tcagcctgga
     6001 agctgggagt ccggcaggga aggagatcca cccaaccttc ttcccctccc atcttgtgcc
     6061 tgagcatacc aacgtccttg gggccaatga tggtcccaag aagctgtctc cacaaccaca
     6121 gtctgtgcag cttttatttc aacaggaaag taataaaatc tatatacagt ctaaaaaaaa
     6181 aaaaaaaaaa
//
