LOCUS       NM_145398               3889 bp    mRNA    linear   ROD 20-OCT-2024
DEFINITION  Mus musculus CAS1 domain containing 1 (Casd1), transcript variant
            1, mRNA.
ACCESSION   NM_145398 XM_909189
VERSION     NM_145398.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3889)
  AUTHORS   Mahajan,V.S., Alsufyani,F., Mattoo,H., Rosenberg,I. and Pillai,S.
  TITLE     Alterations in sialic-acid O-acetylation glycoforms during murine
            erythrocyte development
  JOURNAL   Glycobiology 29 (3), 222-228 (2019)
   PUBMED   30597004
REFERENCE   2  (bases 1 to 3889)
  AUTHORS   Wang,X., Hu,B., Zieba,A., Neumann,N.G., Kasper-Sonnenberg,M.,
            Honsbein,A., Hultqvist,G., Conze,T., Witt,W., Limbach,C.,
            Geitmann,M., Danielson,H., Kolarow,R., Niemann,G., Lessmann,V. and
            Kilimann,M.W.
  TITLE     A protein interaction node at the neurotransmitter release site:
            domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the
            N-terminal domain of Munc13-1
  JOURNAL   J Neurosci 29 (40), 12584-12596 (2009)
   PUBMED   19812333
REFERENCE   3  (bases 1 to 3889)
  AUTHORS   Ono,R., Nakamura,K., Inoue,K., Naruse,M., Usami,T.,
            Wakisaka-Saito,N., Hino,T., Suzuki-Migishima,R., Ogonuki,N.,
            Miki,H., Kohda,T., Ogura,A., Yokoyama,M., Kaneko-Ishino,T. and
            Ishino,F.
  TITLE     Deletion of Peg10, an imprinted gene acquired from a
            retrotransposon, causes early embryonic lethality
  JOURNAL   Nat Genet 38 (1), 101-106 (2006)
   PUBMED   16341224
REFERENCE   4  (bases 1 to 3889)
  AUTHORS   Ono,R., Shiura,H., Aburatani,H., Kohda,T., Kaneko-Ishino,T. and
            Ishino,F.
  TITLE     Identification of a large novel imprinted gene cluster on mouse
            proximal chromosome 6
  JOURNAL   Genome Res 13 (7), 1696-1705 (2003)
   PUBMED   12840045
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC091395.4.
            
            On Mar 24, 2020 this sequence version replaced NM_145398.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB091829.1, BC125379.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-391               AC091395.4         17522-17912
            392-488             AC091395.4         24594-24690
            489-609             AC091395.4         25245-25365
            610-654             AC091395.4         29846-29890
            655-717             AC091395.4         31260-31322
            718-762             AC091395.4         35900-35944
            763-886             AC091395.4         36372-36495
            887-1101            AC091395.4         37683-37897
            1102-1524           AC091395.4         40663-41085
            1525-1614           AC091395.4         42077-42166
            1615-1734           AC091395.4         46573-46692
            1735-1891           AC091395.4         47619-47775
            1892-1971           AC091395.4         48130-48209
            1972-2073           AC091395.4         50613-50714
            2074-2214           AC091395.4         52357-52497
            2215-2292           AC091395.4         53580-53657
            2293-2385           AC091395.4         57526-57618
            2386-3889           AC091395.4         58463-59966
FEATURES             Location/Qualifiers
     source          1..3889
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 1.81 cM"
     gene            1..3889
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /note="CAS1 domain containing 1"
                     /db_xref="GeneID:213819"
                     /db_xref="MGI:MGI:2384865"
     exon            1..391
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     CDS             259..2652
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /EC_number="2.3.1.45"
                     /note="isoform 1 is encoded by transcript variant 1;
                     O-acetyltransferase; CAS1 domain-containing protein 1;
                     sialate O-acetyltransferase; N-acetylneuraminate
                     9-O-acetyltransferase; N-acetylneuraminate
                     (7)9-O-acetyltransferase"
                     /codon_start=1
                     /product="N-acetylneuraminate (7)9-O-acetyltransferase
                     isoform 1"
                     /protein_id="NP_663373.2"
                     /db_xref="CCDS:CCDS19896.1"
                     /db_xref="GeneID:213819"
                     /db_xref="MGI:MGI:2384865"
                     /translation="MAALAYNLGKREINHYFSVRSAKVLALVAVLLLAACHLASRRYR
                     GNDSCEYLLSSGRFLGEKVWQPHSCMMHKYKISEAKTCLVDKHIAFIGDSRIRQLFYS
                     FVKIINPQFKEEGNKHENIPFEDKAASVKVDFLWHPEVNGSMKQCIKVWTEDSVLKPH
                     VIVAGAATWSIKIHNGSEEALAQYKMNITSIAPLLEKLAKTSDVYWVLQDPVYEDLLS
                     ENRKMITNEKIDAYNEAAVSILNSSTRTSKSNVKMFSVSKLIAQETIMESLDGLHLPE
                     SSRETSAMILMNVYCNKVVKPVDGSCCQPRPPLTLIQKLAACFFTLSIIGYFIFYVIH
                     RNAHRKNKPCTDLESGEEKKNIINTPVSSLEILLQSFCKLGLIMAYFYMCDRANLFMK
                     ENKFYTHSSFFIPIIYILVLGVFYNENTKETKVLNREQTDEWKGWMQLVILIYHISGA
                     STFLPVYMHIRVLVAAYLFQTGYGHFSYFWIKGDFGIHRVCQVLFRLNFLVVVLCIVM
                     DRPYQFYYFVPLVTVWFMVIYVTLALWPQITQKKANGNFFWYLGLLLKLGLLLLCIWF
                     LAYSQGAFEKIFSLWPLSKCFELEGSVYEWWFRWRLDRYVVFHGVLFAFIYLALQRRQ
                     ILSEGKGEPLFSNKISNFLLFVSVVSFLTYSIWASSCKNKAECNELHPSVSVVQIVAF
                     ILIRNIPGYARSIYSSFFAWFGKISLELFICQYHIWLAADTRGILVLIPGNPTLNIIV
                     STFIFVCVAHEISQITTDLAQVVIPKDNPSLFRRLACTIAFFGGVLILSSIQDKSRL"
     exon            392..488
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            489..609
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            610..654
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            655..717
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            718..762
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            763..886
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            887..1101
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..1524
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1525..1614
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1734
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1735..1891
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1892..1971
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1972..2073
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            2074..2214
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            2215..2292
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            2293..2385
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     exon            2386..3889
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3844..3849
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /note="hexamer: AATAAA"
     polyA_site      3889
                     /gene="Casd1"
                     /gene_synonym="Cas1; Cas1p; Cast1; SOAT"
                     /note="major polyA site"
ORIGIN      
        1 gagacaggcg gccagggcgc ctggggcacc ggcacggctg agcaacggcg gcggggttgg
       61 ggggaggccg acgagggcac ggggaaggcc ggcggcacgg aggccgcagg ctcggacccc
      121 tcggcccgcg gttcgggcga cgggcaaggg agctggcggc cgcttctcgg ctggctacgg
      181 cgcccgccgc cccagtgctg cccctgcgcg gcgccccttc cccgctccgc cgcgcactgt
      241 tgtcatggag gaaccaagat ggcggctctg gcctacaacc tgggcaagcg ggagatcaac
      301 cactacttca gcgtgaggag cgccaaggtg ctggcgctgg tggccgtgct gctgctcgca
      361 gcgtgccacc tcgcgtcccg ccgctaccga ggcaatgatt cgtgtgaata ccttctctcg
      421 agcggcagat ttcttggaga aaaagtttgg caacctcaca gttgtatgat gcataaatac
      481 aaaataagtg aagcaaagac ttgccttgta gataaacaca ttgcgtttat tggagattcc
      541 aggatccgtc aattatttta ttcttttgta aaaatcatta acccccagtt taaagaagaa
      601 ggaaataagc atgaaaacat tccttttgaa gacaaggctg catcagttaa agtggatttt
      661 ctttggcatc cagaagttaa tggttccatg aaacaatgta tcaaggtgtg gactgaggac
      721 tcggttttga agccccatgt gattgtagca ggagcagcca catggtccat caagattcat
      781 aatggcagcg aggaggcact agctcagtat aaaatgaata tcacctccat agcaccactc
      841 ttagaaaaat tggccaagac tagtgatgtt tattgggtct tacaagaccc agtttatgag
      901 gatctcttaa gtgaaaatag gaaaatgatt accaatgaga agatagacgc ctacaatgag
      961 gctgcagtca gcatcctgaa cagcagcacc aggacctcta agtccaatgt gaagatgttc
     1021 agtgtttcca aactcattgc ccaagagacc atcatggagt ctctggatgg cttacacctt
     1081 cctgaatcga gcagagaaac tagtgcaatg attctcatga acgtgtactg caataaagtt
     1141 gtgaagcctg tggatggttc ctgttgtcag cctcggccac ctctcactct cattcagaag
     1201 ctagctgctt gctttttcac tttatccatt attgggtatt tcattttcta tgtaattcat
     1261 cgtaatgctc accggaagaa taaaccatgt actgatttgg agagtggcga ggaaaagaag
     1321 aatattatca atactcctgt gtcttcatta gaaatacttt tacagtcttt ttgcaaactt
     1381 ggcctgatta tggcttattt ctatatgtgt gaccgtgcaa acctgtttat gaaggaaaac
     1441 aaattttata cacattcatc attctttatt ccaattatct acatcttggt tttgggagta
     1501 ttttacaatg aaaacacaaa agagactaaa gtgttaaata gagagcaaac tgatgaatgg
     1561 aaaggctgga tgcagcttgt gattttgatc tatcacatct cgggagcaag cacatttctg
     1621 cctgtgtaca tgcacattcg agttctggtg gctgcatatc tgtttcagac agggtacggg
     1681 catttctctt acttttggat caaaggagat tttgggattc atagagtgtg tcaggtctta
     1741 tttcgtctca atttcctggt tgtggtgtta tgtatcgtaa tggatcgacc atatcagttc
     1801 tattactttg tccccttggt taccgtgtgg ttcatggtca tatatgtcac tttagcactg
     1861 tggccacaaa taacccaaaa gaaggcaaat ggaaattttt tctggtatct cggcttactg
     1921 ttgaaactag gcttgctgct gctgtgcata tggttcttgg catattctca gggtgcattt
     1981 gagaagatct tttctctatg gccactttcc aaatgttttg aactagaagg gagcgtgtat
     2041 gaatggtggt tcaggtggag gctagaccgc tacgttgtct tccatggggt tctgtttgct
     2101 ttcatttatc tggctttgca gagacggcaa atactttctg aaggaaaggg tgaaccactc
     2161 ttttcaaaca aaatttccaa ctttctattg tttgtttcag tagtgtcttt cttgacctat
     2221 tccatctggg ctagcagctg taagaacaaa gcagagtgta acgaactcca cccatctgtg
     2281 tctgtggtac agattgtagc cttcatcctg ataaggaaca tacctggata tgcccgttct
     2341 atatacagtt ctttttttgc ttggtttgga aaaatttcac tagagctgtt catctgccag
     2401 taccacatct ggctggcagc agacacaagg ggcatcctgg tcctcatccc tggaaacccg
     2461 acactcaaca tcatcgtcag cacgttcatc ttcgtttgtg tggcacatga gatttctcag
     2521 atcaccactg acctcgcgca ggtcgttatt cctaaagata acccgtctct cttccgaagg
     2581 ctggcatgta cgattgcatt ctttggtgga gtcctcatct tatcctccat tcaagataaa
     2641 tcaagactgt aggctcctac aatcctaaca acaaactctt cgggcttact ttgcatctgc
     2701 ctagacgaga aaatcatctg tttgaagata ttaatgactg tgtaaatata aacatttggc
     2761 aacaggacag ttttgtgacg tctgttgaac ttgcgcgatt gtatatatca gccctgtgta
     2821 tatccaatgt gaaatgcaca cagtgaacca ggatgcatcg tataagagtg catgtggaaa
     2881 acccttttct accagatctg tgtctctatt tataggtgat tatagttagc atatgaaggc
     2941 agggaatggt ggactttcca gtaaacctat gtaagtacgt taattaggtt agtgacacca
     3001 ctgtgtgtct tgatatcctc tgactgtgtg gtaatcattg cgtcggcatc tgtgcgccca
     3061 gaccctccta cttcacagac aacttagtac cgaagtgact tgcggtgttc ttccctgtca
     3121 cgtgtgccgt gctgtggaat gagagactgt tatgtcttta acccgtgcac attcacgtcc
     3181 actgtgtttc ctgatgtgat tttttcccta gctgtagttt gcgggtatgt aagcctaaat
     3241 ctttggacac tttgcccttc acagagttgt tctaaagctc ggtgacaagg ttttgttatt
     3301 gtgtatgttg ttgttgctta tttttaaaaa ggccaaattt tccttccaat ccaaacagtc
     3361 tatttctttt tcctaaacta taccagaatt taaaaagaaa agaaaacaaa acaaaacaac
     3421 aacaaaacca aaaaccctac cccatggatc cattagtgtt tgctggtcgc taattaagta
     3481 gagtgtatta tttccaatgt ttggaaggtt ctttataaac acttggtatt gcttattatg
     3541 ccctcatttt ttaaaaaaaa aatatttatc gatctgaacc tgtgcagcat aatgaagttc
     3601 caaatctttg attgaaatgt gtgaccgtag tagaatttta agtaaactgc tgattttgaa
     3661 caataagtga tctgttcgtt ttttataagt aactgttaga ggtatacatt tatttatctg
     3721 ttgtacagat ctgattatga tttttaatgt ataaaatatt gcacttattt gctctcattc
     3781 tgtgtgtggt aagatgtatt ttctgttcat agtgtgtgac aataagaagt aatttaaaca
     3841 gtaaataaac actcagtgga tgcttatttt tgtattggca aagaatcaa
//
