LOCUS       NM_001110807            2828 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus calpain 12 (Capn12), mRNA.
ACCESSION   NM_001110807
VERSION     NM_001110807.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2828)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2828)
  AUTHORS   Cao,C. and Fleming,M.D.
  TITLE     Loss of the placental iron exporter ferroportin 1 causes embryonic
            demise in late-gestation mouse pregnancy
  JOURNAL   Development 149 (23) (2022)
   PUBMED   36398730
REFERENCE   3  (bases 1 to 2828)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   4  (bases 1 to 2828)
  AUTHORS   Dear,T.N., Meier,N.T., Hunn,M. and Boehm,T.
  TITLE     Gene structure, chromosomal localization, and expression pattern of
            Capn12, a new member of the calpain large subunit gene family
  JOURNAL   Genomics 68 (2), 152-160 (2000)
   PUBMED   10964513
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC171210.1 and AC166357.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849382,
                              SAMN01164133 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-305               AC171210.1         8593-8897           c
            306-375             AC171210.1         7933-8002           c
            376-494             AC171210.1         7665-7783           c
            495-628             AC171210.1         7292-7425           c
            629-797             AC171210.1         4657-4825           c
            798-872             AC171210.1         4108-4182           c
            873-958             AC171210.1         3935-4020           c
            959-1033            AC171210.1         3781-3855           c
            1034-1197           AC171210.1         2817-2980           c
            1198-1433           AC171210.1         2498-2733           c
            1434-1445           AC171210.1         2123-2134           c
            1446-1654           AC171210.1         1733-1941           c
            1655-1697           AC171210.1         1438-1480           c
            1698-1757           AC171210.1         1297-1356           c
            1758-1815           AC171210.1         715-772             c
            1816-1886           AC171210.1         327-397             c
            1887-1949           AC171210.1         167-229             c
            1950-2028           AC166357.3         93125-93203         c
            2029-2145           AC166357.3         91379-91495         c
            2146-2204           AC166357.3         91233-91291         c
            2205-2828           AC166357.3         90529-91152         c
FEATURES             Location/Qualifiers
     source          1..2828
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 16.94 cM"
     gene            1..2828
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /note="calpain 12"
                     /db_xref="GeneID:60594"
                     /db_xref="MGI:MGI:1891369"
     exon            1..305
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            306..375
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            376..494
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            495..628
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            629..797
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            798..872
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            873..958
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            959..1033
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1197
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            1198..1433
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            1434..1445
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1654
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            1655..1697
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            1698..1757
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            1758..1815
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            1816..1886
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            1887..1949
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            1950..2028
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            2029..2145
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            2146..2204
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     exon            2205..2828
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2791..2796
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /note="hexamer: AATAAA"
     polyA_site      2817
                     /gene="Capn12"
                     /gene_synonym="CANP 12"
                     /note="major polyA site"
ORIGIN      
        1 ggagccacgc cccccatgac tcaggaggtt aaagggcttg ggtccatctg tgtgcccaga
       61 gtgtccgaat ggcgagtggc aacaggaagg tcaccatcca gctggtggac gacggggccg
      121 ggactggagc tgggggccca cagctcttta aaggccagaa ctacgaagcc atccgaagag
      181 cttgcctgga ttccgggatc ctgtttcgtg acccttgctt tcctgctggc cctgatgccc
      241 ttggctatga caagctggga cctgactcag agaaggccaa aggggtggaa tggaagaggc
      301 cccatgagtt ttgtgctgag ccccagttca tctgtgaaga catgagcaga acagatgtgt
      361 gccagggaag cttgggaaac tgctggcttc ttgcagctgc tgcctccctc acactctacc
      421 ccaggctcct gtaccgggtg gtcccccctg gacaaggttt ccaagatggc tacgcggggg
      481 tcttccattt tcagctatgg cagtttggcc gctgggtgga tgtggtggta gacgacaaac
      541 tgcctgtgcg tgaggggaag ctgatgttcg tgcgctcaga acaaaggaac gagttctggg
      601 cccctctgct ggaaaaggcc tatgccaagc tccatggctc ctacgaggta atgcgaggag
      661 gtcacatgaa cgaggctttt gtggacttta caggaggcgt gggtgaggtc ctctacttga
      721 gacaaaacac tccaggtgtc tttgctgccc ttcgccacgc attggccaag gagtcccttg
      781 tgggtgctac tgccctgagt gatcggggtg agatccgcac agatgaaggg ctggtgaagg
      841 gacatgctta ttctgtcaca ggcacgcaca agatgtctct gggcttcacc aaggtgcggc
      901 tgctgcggct gaggaacccc tggggccgcg tggagtggtc cgggccctgg agtgacagct
      961 gcccacgctg ggacatgctc ccttctgagt ggcgagatgc cctgcttgtg aaaaaggagg
     1021 atggcgagtt ctggatggag cttcaagact ttctcacgca cttcaacaca gtgcagattt
     1081 gttcactgag tcctgaggtg ttgggcccca gccctgctgg cggcggctgg catatccaca
     1141 tcttccaggg ccgctgggtg cgaggcttca actccggtgg gagtcagccc agcgctgaaa
     1201 acttctggac caacccccag ttccggctga cactgctgga gcctgatgag gaagaggatg
     1261 acgatgatga agagggaccc tggggaggct ggggagcggc aggggcccgg ggcccggcga
     1321 gaggaggccg agtccccaag tgcacggtcc tgttgtcact catccagcgc aaccgccggt
     1381 gtctgagggc caagggcctc acttacctca ctgtgggctt ccacgtgttc cagattccgg
     1441 aggagctgct ggacctctgg gactccccgc gcagccgcgc gctcttgccg ggactgctgc
     1501 gcgccgaccg ctcggttttc tgcgcccgcc gcgacgtgag ccgtcgctgt cgcctgccgc
     1561 ctggccacta cctggtggta cccagcgcct cgcgcgtagg cgatgaagcc gacttcactc
     1621 tgcgcatctt ctcggagcgc agccacaccg cagtggagat cgatgacgtg atcagcgcag
     1681 acctggacgc cctccaggcc ccctacaagc ccctggagct ggagttggca cagctatttt
     1741 tggagctggc tggagaggag gaggaactca acgcgcttca gctgcagacc ttaataagca
     1801 ttgctctgga acctgcgagg gccaacacca ggacccctgg agagattggg cttaggacct
     1861 gcgaacagct tgtgcagtgt tttgggcgtg ggcaaagact gtccctacac cacttccagg
     1921 agctctgggg ccatctcatg tcatggcagg ccacatttga caagtttgat gaagatgcct
     1981 ctgggacaat gaactcctgt gaactgaggc tggcactgac tgctgcaggc ttccacctca
     2041 acaaccagct gacccagtcc ctcactagcc gctaccggga cagccggctc cgtgtggact
     2101 tcgagcgctt cgtgtgctgt gcagcccggc tcacctgcat cttccgccac tgctgccaac
     2161 acctggatgg cggcgagggg gtcgtctgcc tgacccacaa acagtggtcg gaggtggcta
     2221 ccttctcata ggtttgaagc tgagggaggt caccctgctg cccgactcac tgtcacaaag
     2281 gtggtggcta tgtaaccctg gccggcctca caagtgctgg gattacgagc tggagccatc
     2341 ccaaacagaa ctgccaccct tccttttgaa gcctcttcat gtcagtccct gcttagagag
     2401 gggcacaacc cccacacagg cactgggctg gtgggcactg ccagctcctt ggggcatgaa
     2461 cagagatgca gggagaagat gacaccagag tccttcttaa aaatattaca tgttttattc
     2521 tcccatcccc agagggtggt ttatccagaa accaagaaaa taaaaatcaa tcagaataaa
     2581 ctcaaggggg cgagtggaga gaaacccatt aacgaccagg caggcaggcc agcagcctgc
     2641 ctccacctca gaaggtcccc agagacctct gcccaccgcc acgaggggaa aatcaggagg
     2701 gactggggag ggcattgaat cagctatgtc ttcattatga gagtgagaga ggtggcagag
     2761 atatgcagct agatggatat atatttatat aataaatccg taagttaata aagtaaatag
     2821 taattctc
//
