LOCUS       NM_001347109            7805 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus calmodulin regulated spectrin-associated protein
            family, member 2 (Camsap2), transcript variant 2, mRNA.
ACCESSION   NM_001347109 XM_006529833
VERSION     NM_001347109.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7805)
  AUTHORS   Zhou,Z., Yang,X., Mao,A., Xu,H., Lin,C., Yang,M., Hu,W., Shao,J.,
            Xu,P., Li,Y., Li,W., Lin,R., Zhang,R., Xie,Q., Xu,Z. and Meng,W.
  TITLE     Deficiency of CAMSAP2 impairs olfaction and the morphogenesis of
            mitral cells
  JOURNAL   EMBO Rep 25 (7), 2861-2877 (2024)
   PUBMED   38839944
  REMARK    GeneRIF: Deficiency of CAMSAP2 impairs olfaction and the
            morphogenesis of mitral cells.
REFERENCE   2  (bases 1 to 7805)
  AUTHORS   Zuo,L., Wang,L., Yang,Z., Li,J., Wang,W., Li,J., Wang,Y., Song,X.,
            Zhnag,X. and Geng,Z.
  TITLE     [High expression of CAMSAP2 promotes invasion and metastasis of
            gastric cancer cells by upregulating TGF-beta signaling]
  JOURNAL   Nan Fang Yi Ke Da Xue Xue Bao 43 (9), 1460-1468 (2023)
   PUBMED   37814859
  REMARK    GeneRIF: [High expression of CAMSAP2 promotes invasion and
            metastasis of gastric cancer cells by upregulating TGF-beta
            signaling].
REFERENCE   3  (bases 1 to 7805)
  AUTHORS   Wang,X., Liu,Y., Ding,Y. and Feng,G.
  TITLE     CAMSAP2 promotes colorectal cancer cell migration and invasion
            through activation of JNK/c-Jun/MMP-1 signaling pathway
  JOURNAL   Sci Rep 12 (1), 16899 (2022)
   PUBMED   36207462
  REMARK    GeneRIF: CAMSAP2 promotes colorectal cancer cell migration and
            invasion through activation of JNK/c-Jun/MMP-1 signaling pathway.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7805)
  AUTHORS   Liu,H., Zheng,J., Zhu,L., Xie,L., Chen,Y., Zhang,Y., Zhang,W.,
            Yin,Y., Peng,C., Zhou,J., Zhu,X. and Yan,X.
  TITLE     Wdr47, Camsaps, and Katanin cooperate to generate ciliary central
            microtubules
  JOURNAL   Nat Commun 12 (1), 5796 (2021)
   PUBMED   34608154
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7805)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7805)
  AUTHORS   Nakagawa,N., Plestant,C., Yabuno-Nakagawa,K., Li,J., Lee,J.,
            Huang,C.W., Lee,A., Krupa,O., Adhikari,A., Thompson,S., Rhynes,T.,
            Arevalo,V., Stein,J.L., Molnar,Z., Badache,A. and Anton,E.S.
  TITLE     Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral
            Cortical Development
  JOURNAL   Neuron 103 (5), 836-852 (2019)
   PUBMED   31277925
REFERENCE   7  (bases 1 to 7805)
  AUTHORS   Pongrakhananon,V., Wattanathamsan,O., Takeichi,M., Chetprayoon,P.
            and Chanvorachote,P.
  TITLE     Loss of CAMSAP3 promotes EMT via the modification of
            microtubule-Akt machinery
  JOURNAL   J Cell Sci 131 (21) (2018)
   PUBMED   30282632
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 7805)
  AUTHORS   Pongrakhananon,V., Saito,H., Hiver,S., Abe,T., Shioi,G., Meng,W.
            and Takeichi,M.
  TITLE     CAMSAP3 maintains neuronal polarity through regulation of
            microtubule stability
  JOURNAL   Proc Natl Acad Sci U S A 115 (39), 9750-9755 (2018)
   PUBMED   30190432
REFERENCE   9  (bases 1 to 7805)
  AUTHORS   Hendershott,M.C. and Vale,R.D.
  TITLE     Regulation of microtubule minus-end dynamics by CAMSAPs and
            Patronin
  JOURNAL   Proc Natl Acad Sci U S A 111 (16), 5860-5865 (2014)
   PUBMED   24706919
REFERENCE   10 (bases 1 to 7805)
  AUTHORS   Tanaka,N., Meng,W., Nagae,S. and Takeichi,M.
  TITLE     Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific
            organization of noncentrosomal microtubules
  JOURNAL   Proc Natl Acad Sci U S A 109 (49), 20029-20034 (2012)
   PUBMED   23169647
  REMARK    GeneRIF: CAMSAP2 and -3 work together to maintain noncentrosomal
            microtubules in epithelial cells, suppressing the
            microtubule-organizing ability of the centrosome.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC120875.12 and AC124550.4.
            
            On Nov 16, 2016 this sequence version replaced XM_006529833.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC138367.1, SRR1660817.105324.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-806               AC120875.12        155681-156486       c
            807-1066            AC120875.12        135119-135378       c
            1067-1228           AC120875.12        114677-114838       c
            1229-1312           AC120875.12        108124-108207       c
            1313-1345           AC120875.12        107666-107698       c
            1346-1487           AC120875.12        103662-103803       c
            1488-1627           AC120875.12        103262-103401       c
            1628-1721           AC120875.12        98282-98375         c
            1722-1815           AC120875.12        96291-96384         c
            1816-1850           AC120875.12        94249-94283         c
            1851-1920           AC120875.12        93194-93263         c
            1921-2388           AC120875.12        92414-92881         c
            2389-4114           AC124550.4         202863-204588       c
            4115-4251           AC124550.4         199751-199887       c
            4252-4472           AC124550.4         199095-199315       c
            4473-4545           AC124550.4         197358-197430       c
            4546-4661           AC124550.4         196307-196422       c
            4662-4780           AC124550.4         194088-194206       c
            4781-7805           AC124550.4         190680-193704       c
FEATURES             Location/Qualifiers
     source          1..7805
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 59.61 cM"
     gene            1..7805
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /note="calmodulin regulated spectrin-associated protein
                     family, member 2"
                     /db_xref="GeneID:67886"
                     /db_xref="MGI:MGI:1922434"
     exon            1..806
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     CDS             668..5086
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /note="isoform 2 is encoded by transcript variant 2;
                     calmodulin-regulated spectrin-associated protein 2;
                     calmodulin-regulated spectrin-associated protein 1-like
                     protein 1"
                     /codon_start=1
                     /product="calmodulin-regulated spectrin-associated protein
                     2 isoform 2"
                     /protein_id="NP_001334038.1"
                     /db_xref="CCDS:CCDS83598.1"
                     /db_xref="GeneID:67886"
                     /db_xref="MGI:MGI:1922434"
                     /translation="MGDAADPREMRRTFIVPAIKPFDHYDFSRAKIACNLAWLVAKAF
                     GTENVPEELGDPFYTDQYDQEHIKPPVVNLLLSAELYCRAGSLILKSDAAKPLLGHDA
                     VIQALAQKGLYVTDQEKLVTERDLHKKPIQMSAHLAMIDTLMMAYTVEMISIEKVIAC
                     AQQYSAFFQATDLPYDIEDAVMYWMNKVNEHLKDIMEQEQKSKEHHPAEAPGGQKSPS
                     KWFWKLVPARYRKEQTLLKQLPCIPLVENLLKDGTDGCALAALIHFYCPAVVRLEDIC
                     LKETMSLADSLYNLQLIQEFCQEYLNHCCHFSLEDMLYAASSIKSNYLVFMAELFWWF
                     EVVKPSFVQPRVVRPQGAEPAKDVPSVPVLNAAKRNIRDSSSSSDFSSRYTRPQTHSS
                     ASGGIRRSSSMSYVDGFIGTWPKEKRTSVHGVSFDISFDKEDSAQSSTPNRGIIRSVS
                     NEGLTLNNSRASKHIRKNLSFKPVNGEEEESIEEELHVDPHGDLQSPMPLNTNELNSN
                     ESTHYKLPNGALQNRVLLDEFGNQIETPSIEEALQIIHDTERPPHTPRPDQIANGFFL
                     HGQDLSILNSNIKLNQSSPDNLTDTKGALSPITDTTEVDTGIHVPSEDIPETMDEDSS
                     LRDYTVSLDSDMDDASKLLQDYDLRASNPREALSPCPSTISTKSQPGSSASSSSGVKM
                     TSFAEQKFRKLNHTDGKSSGSSSQKTTPEGSELNIPHVVSWAQIPEEAGVAPGRDTTQ
                     LLASEMVHLRMRLEEKRRAIEAQKKKMEAAFTKQRQKMGRTAFLTVVKKKGEGISPLR
                     EEAAGAEDEKVYTDRAKERESQKMDGQRSKSLADIKESMETPPGRWLKSPTTPVDPER
                     QWNLTSPSEETLNEGEILEYTKSIEKLNSSLHFLQQEMQRLSLQQEMLMQMREQQAWV
                     ISPPQPSPQKQIRDFKPRQAGLSSAAAPFSSDSPRPTHPSPQSSTRKSASFSVKNQRT
                     PRPNELKITPLNRTLTPPRSVDSLPRLRRFSPSQVPIQTRSFVCFGDDGEPQKEPKQK
                     EEIKKEPSECKGTLGPCDHNPGEKEIKPVESTVSEVLSQPITETVCVTPNEDQLSQPT
                     EPPPKPVFPPTAPKNVNLIEVSLSDLKPPEKADVSVEKLDGESDKEQFDDDQKVCCGF
                     FFKDDQKAENDMAMKRAALLEKRLRREKETQLRKQQLEAEMEHKKEETRRKTEEERQK
                     KEDERARREFIRQEYMRRKQLKLMEDMDTVIKPRPQAAKQKKQRPKSIHRDHIESPKT
                     PIKGPPVSSLSLASLNTGDSESVHSGKRTPRSESVEGFLSPSRCGSRNGEKDWENAST
                     TSSVASGTEYTGPKLYKEPSAKSNKHIIQNALAHCCLAGKVNEGQKKKILEEMEKSDA
                     NNFLILFRDSGCQFRSLYTYCPETEEINKLTGIGPKSITKKMIEGLYKYNSDRKQFSH
                     IPAKTLSASVDAITIHSHLWQTKRPVTPKKLLPTKA"
     exon            807..1066
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1228
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            1229..1312
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1345
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..1487
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            1488..1627
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            1628..1721
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            1722..1815
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            1816..1850
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            1851..1920
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            1921..4114
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            4115..4251
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            4252..4472
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            4473..4545
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            4546..4661
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            4662..4780
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     exon            4781..7805
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6742..6747
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /note="hexamer: ATTAAA"
     polyA_site      6768
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /note="major polyA site"
     regulatory      7654..7659
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /note="hexamer: AATAAA"
     polyA_site      7675
                     /gene="Camsap2"
                     /gene_synonym="1600013L13Rik; 4930541M15Rik; Camsap1l1;
                     mKIAA1078"
                     /note="major polyA site"
ORIGIN      
        1 agtgccgcag ccggaaaacc gcagcgacgg cggcggcggc ggctgaaggg gagcgaggcg
       61 tccggccacg ggaggggtag cggaaaatac gaggacaagc ccgataaggc aggagccgag
      121 ggcccgtgat ttgatttgcg gcctccccca ggccgctgcc ttggccctga gctgcgccga
      181 ggaggcgggc ggcggcgatc ggagcgccgg agaagcgccg ggccgcgggc ggctcgcgcg
      241 ctgcagcgat tctgacgttt tccgcggcgg gtcccgcggc ccgaggggcg gccgtgagtg
      301 aggcggggcg tgcgcgctcc gccatggcgg ggacactgtc cgcgacgtga tcgtccaggc
      361 tgcccccgcc cgagcattcc gggccctctc agccgccacc ctcctgcgag cccgtgtgac
      421 taaacggaga caaaggggag gcggaggggc agacccgggc cggagcgagc gcggccgggt
      481 gccgcctcac gtctatgccc ggggccgcgg cggctcccgc gggcggcgga ctcgcgacga
      541 gcacagctga gcttttccgt gcccggcgcc cgggagggcc gcgaccggcg cggacgatct
      601 gaactcctct ctccgccaca ccatgtgaag gccgtcgtcc ctccatccca accagccgcc
      661 gtgaaagatg ggggatgctg cagacccgcg ggagatgaga aggacgttca ttgttccagc
      721 catcaaaccc tttgaccact atgacttctc cagggccaaa atcgcctgca atctggcctg
      781 gctggtggcc aaagcctttg ggacagaaaa tgtgcccgag gagcttggcg acccatttta
      841 cacagaccag tatgaccagg agcacatcaa accccctgtc gttaacctgc ttctgtcggc
      901 cgagctgtac tgtcgcgctg gaagcctcat cctcaagagc gatgctgcaa agcccctcct
      961 gggccatgat gctgtgatcc aggcattagc acagaaaggc ctgtatgtca ctgaccagga
     1021 gaaactggta actgaaagag atctccacaa gaaacccata cagatgagtg cacatttggc
     1081 tatgattgat actctaatga tggcttacac tgtagagatg atcagcatag aaaaagtaat
     1141 tgcatgtgct caacagtatt cagctttttt tcaagccaca gatctgccct atgatattga
     1201 ggatgctgtc atgtactgga tgaataaggt aaatgaacac ttgaaagaca taatggaaca
     1261 agaacaaaaa tctaaagagc accacccagc tgaagctcca ggaggccaaa agtctccttc
     1321 caaatggttt tggaaactgg ttccagctcg ttacaggaag gaacaaacac tgcttaagca
     1381 actgccttgc attccattgg tggaaaactt gttgaaggat gggaccgacg gctgcgcact
     1441 agctgccctc attcacttct actgccctgc tgttgtccgg ctagaggata tttgtttgaa
     1501 agaaactatg tctttggctg acagtctgta caatctacag ctgattcagg aattttgcca
     1561 agaatactta aaccattgct gccatttcag cttggaagat atgctttatg ctgcttcatc
     1621 cataaagagt aattatttgg tgttcatggc agaactcttc tggtggtttg aagttgtgaa
     1681 gccttcattt gtgcagcctc gtgttgtccg tccacaagga gctgagcctg caaaagacgt
     1741 gccatcggtt cctgtcttaa atgctgccaa aagaaacatc cgggatagtt catctagttc
     1801 tgacttctcc tccagatata cacggccgca gactcattct tcagcctcag gaggaattag
     1861 aaggtcttca tctatgtctt atgttgatgg cttcatagga acgtggccta aagagaaaag
     1921 aacatcagtg catggcgttt cattcgacat ttcttttgat aaagaagaca gtgcgcagag
     1981 ctccactcca aaccggggaa tcatccgctc tgttagcaat gaagggctca ctctcaacaa
     2041 cagccgtgca tccaagcaca ttaggaaaaa tctgtccttc aagccagtga acggagaaga
     2101 ggaggagagc attgaggaag agcttcatgt cgaccctcat ggtgacctcc aatcacccat
     2161 gcctctcaac acgaatgaac tgaactctaa tgagagtact cactacaagc ttccaaatgg
     2221 ggctttacaa aacagagtgc ttctagacga gttcgggaat cagatagaaa cgccaagcat
     2281 tgaagaagcg ttacagataa tccacgatac tgaaagacct cctcatacgc cacggccaga
     2341 tcagatcgct aatggcttct ttcttcatgg tcaagatcta agtatcctga attcaaatat
     2401 caagctaaac cagtccagtc ctgataactt aactgacaca aaaggtgcct tgagtcccat
     2461 aacagacact acagaagtcg acactggaat tcacgttcct tcagaagaca ttccggagac
     2521 catggacgaa gactcctcct tgagagatta tactgttagc ttagactccg acatggatga
     2581 tgcatctaag cttcttcagg actatgacct aagagccagc aaccccaggg aagccctgag
     2641 tccttgccca agcaccatca gcaccaagtc tcagcccggg agcagtgcct cgtctagctc
     2701 tggggtgaag atgaccagct ttgctgagca gaagttcagg aagctgaatc acactgatgg
     2761 gaaaagtagc gggagcagtt cacagaaaac cacaccagaa ggctcagaac tgaatattcc
     2821 tcacgtggtg tcttgggctc aaattccaga ggaagcgggt gttgccccag gtcgggacac
     2881 gacacagctg ttggcttctg agatggtgca ccttaggatg aggctggagg aaaagagacg
     2941 tgcgatagaa gcccagaaga agaagatgga agccgctttt accaaacaga ggcagaaaat
     3001 gggaaggaca gcgttcctga ctgtagtgaa gaagaaaggg gaagggattt cccctctccg
     3061 agaggaagca gcaggtgcag aagacgagaa agtatatacg gaccgagcaa aggaaaggga
     3121 gtcacagaaa atggacggac agaggagcaa gtccttggca gacataaaag agagcatgga
     3181 gacccctcca ggcagatggc tgaagtcgcc aaccacgcct gttgatcctg agaggcagtg
     3241 gaacctgaca agcccttcag aagagacttt aaatgaagga gaaatcttag agtatacaaa
     3301 gtcgattgaa aagctgaatt catccttgca ctttctacaa caagaaatgc agcgcttgtc
     3361 ccttcagcag gagatgttaa tgcagatgag agagcagcag gcctgggtga tttcacctcc
     3421 gcaaccctct ccacagaagc agatccgcga ttttaaacct agacaggcag gcctgtcatc
     3481 agctgctgca ccgttctctt cagactcccc acgcccaact cacccatccc cacagtcttc
     3541 caccaggaag agcgcgtctt tttctgttaa aaatcaaagg actccaaggc caaatgaatt
     3601 aaaaataact cctttgaacc gaaccttgac acctcctcgg tctgtggata gccttcctcg
     3661 gctaaggagg ttttccccaa gtcaggttcc cattcagaca cggtcatttg tatgctttgg
     3721 tgatgatgga gagccccaaa aagagcccaa acagaaagag gagattaaaa aggagccctc
     3781 agagtgcaaa gggactttgg gaccttgtga ccataatcct ggggagaagg agattaaacc
     3841 tgttgaatca acagtgtctg aggtgttgtc acagcctatc acagagactg tgtgtgtgac
     3901 accaaatgag gaccaactga gccagcccac agagccacct cctaaacctg ttttcccacc
     3961 tactgctcct aaaaatgtca atctgattga agtttctctg tccgatttaa aaccccctga
     4021 aaaggctgat gtatctgttg agaagttgga tggagagagt gataaggaac agtttgacga
     4081 tgaccagaaa gtatgctgtg gcttcttctt taaggatgat caaaaggcag agaatgatat
     4141 ggcaatgaag cgagcagctt tgctggagaa acggctaaga agagagaaag agactcagct
     4201 tcggaagcag caactggaag cggagatgga gcataagaaa gaggagacga gacgaaaaac
     4261 tgaagaagaa cgtcagaaga aggaagacga gcgagcacgg agagagttta tcaggcagga
     4321 atacatgagg aggaaacagc tgaaactgat ggaagacatg gatacagtaa tcaagcctcg
     4381 acctcaggcg gctaaacaga aaaaacagcg gccaaaatcc attcacagag atcatattga
     4441 atctcccaaa acaccgatca aaggccctcc agtctctagc ctctcattgg catcgctgaa
     4501 cacaggtgat agcgagagtg ttcattcggg caagaggacg ccaaggtcgg agtctgtaga
     4561 aggcttctta tctccaagtc gttgtggcag tcggaatggc gagaaagact gggaaaacgc
     4621 atccacaact tcttcggtgg cttctggaac agagtacaca ggaccaaagc tttacaagga
     4681 acctagtgca aaatccaata aacacataat acagaatgct ttagctcatt gctgtctggc
     4741 tggaaaagta aatgaaggtc agaagaaaaa aatcctagag gaaatggaga agtcagatgc
     4801 caacaacttc ttaatcttgt tccgggattc aggctgccag ttcaggtctt tgtatactta
     4861 ctgcccagaa actgaagaaa tcaataaact gactgggata ggtcctaaat ctatcactaa
     4921 aaagatgatt gagggacttt acaagtacaa ttctgacaga aaacagttta gccacatacc
     4981 tgctaaaact ttatctgcta gcgtggatgc gattaccatt catagccact tatggcagac
     5041 caagagacca gtaaccccaa aaaaactctt acccactaaa gcataggcag caggagatgc
     5101 tcgcttcaga acctttgtgg taaatttgta cttcgtcttt cctgcctata gaaaaacctt
     5161 tctaattgcc aacaagattt ttatcaatta aaactggacc ttaactctgt tgttgtgaac
     5221 aactggaatg taatcacagt gtttggaatg ccgacggttc ttactaggtg ataagtccac
     5281 gcgatgaagg aaatgctttg attcacaggc ggagatttgc atgctagcag gctcacctgc
     5341 ctgtgttaga gaccgtgcag cactgaattc tcatggacac agcgggacat aggcttgagg
     5401 tgtggctaga tggcaattat gtgatgtatt ctttttaccc ctgtactgtg tgtgcacatc
     5461 gtcaaatggt ttcgttgttg ttgtcgtcgt tctgttccct ctcctggggt tattctaagc
     5521 tgcctttgtg tttgttttat gtggagatca tgaaagtaga aagttcctgt tgaaaagtac
     5581 cttgcacctt tcatatgatg gtaagagaga cactagtatt agttttacag tagccctcgt
     5641 gttctgatgg tgttacagta tttgcaagaa tccttctaag tatttacatt ctgtatttat
     5701 tattcacaca agtattaaca tttctctatt agtaaggagg tgtttaaaag ctgctgctgg
     5761 gtcccctgca gaccacacaa gctaacccag cacatcctgt aagaggctgc tgatgaaatc
     5821 agtgctggtt gtctctacac cacttctgcc aactcagaac aaatcagatt gtacttttaa
     5881 caacagagca ctttgtattg catttaaagt gcgtcactgt ataaggtggc agaagtgagt
     5941 gagtgacacg tgagtgctgc ctttctgtat gaaagcatac agcttcctgg cagctcagga
     6001 ggcctttata tttataaccg atagggaaat tatatttagg atttttaaac atgcacaaag
     6061 ggctacattt tgatttgaaa gtagcttcct gttattttac ttatactggg ttttctttcc
     6121 tttgaatcct tttccagtgg aacagcttag attcagggca cacttgaaat ctcctctcca
     6181 tgatctttct tctttagcaa gcataccaga gtaagttggg gggaaacttc attctcagga
     6241 aaagacttga atgattgatt gtgtggccct tttatgtttc agtgttgtga caactgtgta
     6301 cactagtggg gaagacattg tttataagtg agagagtagt ttgttttctt tcatgggata
     6361 tagagatgaa atatgtacat ttctctaatt aagttgttta gagagggaac tcatgtctca
     6421 tgttatgtat ttacttattt aaaaagaaga atggaatggg aagtccctca gctgtacttt
     6481 tctattataa agcctttagg gatcagtgca tctgggtttt caacattttc tcaaatgctg
     6541 tcaatatttt actgtaattt atgttcttat atttatgtat atttgttaaa actgtaaaaa
     6601 aatttttcac agattttttt ccaatacctg tgcaaaatgt atgtgtagct caagactatt
     6661 tgtgatctac tgcttgcatg tgagagacca ggatatgtaa ctcttatatt ttaaatgtat
     6721 acatactgtg tatatataaa tattaaaaac ggggaatttc acattttacc tttcagacac
     6781 caatttttat cacaattaga aggaaatggg caaacaaaga catccttacg ataagattag
     6841 tttaagagtt ataaacaaac ttaatcaaaa caaagtgaat tatagacaaa ggaatttaat
     6901 aagcattttc tactactaac caaggtcttt tccctatcaa agcagcctca tggctgtcac
     6961 ctgagtactg aataaagaaa agtcaggtgc aggacattga gagaactaat gaacactgac
     7021 ctcgcctgtc ttcgttcttc catctgtaca tccagcaact gagcggaatg tctagtgtct
     7081 aaaggtgtga tgtgaatatt gccacaaagt tcattgctct cagtataaga ttttacttta
     7141 ttaatgcaag aggaatacag atatatttct ttagtctgca gatttttttt tattatggtg
     7201 cagcttttta aattatgttt taaaattata caaatgaaaa aatgccattc cataaagttt
     7261 ggagatttcc atccacctta ctgaaacaca agcgttgtca tcgttggagg tcaaattacc
     7321 atggtaacta ctcagttaaa tctgccaaat ccttgtcatg gtaaccagtg tggcctgtca
     7381 actcctgcta cttaccacaa cttctaaagt tttcctctca gtttctcagt tttgtttagg
     7441 aggactattg tttgtatttg gctgctcaca gccagagtct ccttctttga tgtgactcat
     7501 ggacactgtt gggcgatgtg cagtgtgtag tgtgcttcct gtccactcct gagcgctgca
     7561 gatgatccgt caggcttgct cgttcctggg ggttacagtg tagttcccct ttcatctgaa
     7621 taaaagcatg gcaccaactg acgctgattc ttcaataaag tgcgtgttgt cttgtcttgt
     7681 gtttgataac gttatttgga ctcaggaaaa tacatcatga agttttcttg tctcagccta
     7741 ggtttaaatt tagtaattga atatttacct aagtaatttt taatattaaa ttatgcttga
     7801 atgcc
//
