LOCUS       NM_001408050            8041 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus calmodulin regulated spectrin-associated protein 1
            (Camsap1), transcript variant 5, mRNA.
ACCESSION   NM_001408050 XM_006497898
VERSION     NM_001408050.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8041)
  AUTHORS   Zhang,S., Li,H., Jiang,W., Chen,X., Zhou,H., Wang,C., Kong,H.,
            Shi,Y. and Shi,X.
  TITLE     CircCamsap1 is dispensable for male fertility in mice
  JOURNAL   PeerJ 12, e17399 (2024)
   PUBMED   38799061
  REMARK    GeneRIF: CircCamsap1 is dispensable for male fertility in mice.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8041)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 8041)
  AUTHORS   Khalaf-Nazzal,R., Fasham,J., Inskeep,K.A., Blizzard,L.E.,
            Leslie,J.S., Wakeling,M.N., Ubeyratna,N., Mitani,T., Griffith,J.L.,
            Baker,W., Al-Hijawi,F., Keough,K.C., Gezdirici,A., Pena,L.,
            Spaeth,C.G., Turnpenny,P.D., Walsh,J.R., Ray,R., Neilson,A.,
            Kouranova,E., Cui,X., Curiel,D.T., Pehlivan,D., Akdemir,Z.C.,
            Posey,J.E., Lupski,J.R., Dobyns,W.B., Stottmann,R.W., Crosby,A.H.
            and Baple,E.L.
  TITLE     Bi-allelic CAMSAP1 variants cause a clinically recognizable
            neuronal migration disorder
  JOURNAL   Am J Hum Genet 109 (11), 2068-2079 (2022)
   PUBMED   36283405
  REMARK    GeneRIF: Bi-allelic CAMSAP1 variants cause a clinically
            recognizable neuronal migration disorder.
REFERENCE   4  (bases 1 to 8041)
  AUTHORS   Patel,S.D., Anand,D., Motohashi,H., Katsuoka,F., Yamamoto,M. and
            Lachke,S.A.
  TITLE     Deficiency of the bZIP transcription factors Mafg and Mafk causes
            misexpression of genes in distinct pathways and results in lens
            embryonic developmental defects
  JOURNAL   Front Cell Dev Biol 10, 981893 (2022)
   PUBMED   36092713
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8041)
  AUTHORS   Liu,H., Zheng,J., Zhu,L., Xie,L., Chen,Y., Zhang,Y., Zhang,W.,
            Yin,Y., Peng,C., Zhou,J., Zhu,X. and Yan,X.
  TITLE     Wdr47, Camsaps, and Katanin cooperate to generate ciliary central
            microtubules
  JOURNAL   Nat Commun 12 (1), 5796 (2021)
   PUBMED   34608154
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 8041)
  AUTHORS   Zhou,Z., Xu,H., Li,Y., Yang,M., Zhang,R., Shiraishi,A.,
            Kiyonari,H., Liang,X., Huang,X., Wang,Y., Xie,Q., Liu,S., Chen,R.,
            Bao,L., Guo,W., Wang,Y. and Meng,W.
  TITLE     CAMSAP1 breaks the homeostatic microtubule network to instruct
            neuronal polarity
  JOURNAL   Proc Natl Acad Sci U S A 117 (36), 22193-22203 (2020)
   PUBMED   32839317
REFERENCE   7  (bases 1 to 8041)
  AUTHORS   Chen,Y., Zheng,J., Li,X., Zhu,L., Shao,Z., Yan,X. and Zhu,X.
  TITLE     Wdr47 Controls Neuronal Polarization through the Camsap Family
            Microtubule Minus-End-Binding Proteins
  JOURNAL   Cell Rep 31 (3), 107526 (2020)
   PUBMED   32320668
REFERENCE   8  (bases 1 to 8041)
  AUTHORS   Hendershott,M.C. and Vale,R.D.
  TITLE     Regulation of microtubule minus-end dynamics by CAMSAPs and
            Patronin
  JOURNAL   Proc Natl Acad Sci U S A 111 (16), 5860-5865 (2014)
   PUBMED   24706919
REFERENCE   9  (bases 1 to 8041)
  AUTHORS   Yoshioka,N., Asou,H., Hisanaga,S. and Kawano,H.
  TITLE     The astrocytic lineage marker calmodulin-regulated
            spectrin-associated protein 1 (Camsap1): phenotypic heterogeneity
            of newly born Camsap1-expressing cells in injured mouse brain
  JOURNAL   J Comp Neurol 520 (6), 1301-1317 (2012)
   PUBMED   22095662
  REMARK    GeneRIF: Camsap1-expressing cells exhibit regional heterogeneity in
            an early phase after stab injury of mouse brain.  Newly born
            reactive astrocytes are derived from heterogeneous
            Camsap1-expressing cells in the injured brain.
REFERENCE   10 (bases 1 to 8041)
  AUTHORS   Yamamoto,M., Yoshimura,K., Kitada,M., Nakahara,J., Seiwa,C.,
            Ueki,T., Shimoda,Y., Ishige,A., Watanabe,K. and Asou,H.
  TITLE     A new monoclonal antibody, A3B10, specific for astrocyte-lineage
            cells recognizes calmodulin-regulated spectrin-associated protein 1
            (Camsap1)
  JOURNAL   J Neurosci Res 87 (2), 503-513 (2009)
   PUBMED   18756519
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL731682.20.
            
            On Jun 9, 2022 this sequence version replaced XM_006497898.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784643.1507237.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-498               AL731682.20        183280-183777       c
            499-761             AL731682.20        167184-167446       c
            762-923             AL731682.20        166161-166322       c
            924-1004            AL731682.20        156745-156825       c
            1005-1064           AL731682.20        154413-154472       c
            1065-1206           AL731682.20        153176-153317       c
            1207-1346           AL731682.20        145632-145771       c
            1347-1443           AL731682.20        145440-145536       c
            1444-1621           AL731682.20        144924-145101       c
            1622-1713           AL731682.20        141876-141967       c
            1714-1798           AL731682.20        141363-141447       c
            1799-4166           AL731682.20        138444-140811       c
            4167-4303           AL731682.20        137013-137149       c
            4304-4512           AL731682.20        136348-136556       c
            4513-4615           AL731682.20        135960-136062       c
            4616-4731           AL731682.20        134718-134833       c
            4732-4850           AL731682.20        134089-134207       c
            4851-8041           AL731682.20        127336-130526       c
FEATURES             Location/Qualifiers
     source          1..8041
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 18.29 cM"
     gene            1..8041
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /note="calmodulin regulated spectrin-associated protein 1"
                     /db_xref="GeneID:227634"
                     /db_xref="MGI:MGI:3036242"
     exon            1..498
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     CDS             342..5153
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /note="isoform 5 is encoded by transcript variant 5"
                     /codon_start=1
                     /product="calmodulin-regulated spectrin-associated protein
                     1 isoform 5"
                     /protein_id="NP_001394979.1"
                     /db_xref="GeneID:227634"
                     /db_xref="MGI:MGI:3036242"
                     /translation="MVDAGGRCAAEGWRRMEAPPEGADLVPLDRYDAARAKIAANLQW
                     ICAKAYGLDNIPEDLRDPFYIDQYEQEHIKPPVIKLLLSSELYCRVCSLILKGDQVAT
                     LQGHQSVIQALSRKGIYVMESDDTPVTDADLSQAPIKMSGHMAMVDALMMAYTVEMIS
                     IEKVVASVKRFSTFSASKELPYDLEDAMVFWINKVNLKMREITEKEVKLKQQPLESPA
                     HQKPGLEHAVMHCMLEPVDFARVVRYRREHLSARQSPYFPLLEDLMRDGSDGAALLAV
                     VHYYCPEQMKLDDICLKEVPSMADSLYNIRLLREFSNEHLNKCFYLTLEDMLYAPLVL
                     KPNVMVFIAELFWWFENVKPDFVQPRDIQELKDAKTVLQQKSSRPPVPISNATKRSFL
                     GSPAAMSPADQPPSTQPLAEGSHRYHLHSEEPECLGKGASTFSPSHPLLPLRQKQQKV
                     SQTEEIPDQRHRSNSLTRVDGQPRGAIGAWPDKKNRPVSQPTSFALHHAASCDVDPSS
                     GDSVSLARSISKDSLASNIIHLTPQNQPHPSAGKSNGKSLLSNVNIEDEDEELVAIIR
                     TDVSPPSPQMPRTSPQAPGLVASIRSPQRQADTLESKPDSFYLEPLMPAVLRPAKEKQ
                     ITTKEDERGEGRPRTIMAKRPSEGSQPMVRKKVSGGHGSRDLNRTFTPIPCSEFAASI
                     DLAEVGPQSAEATGEGQPLALGRFDTLPQGQAADGFFLHVGRAEEDEGRWYVGSQSPS
                     SHDSEPWTILRQDSDSDVVDVEDTEQDFIGEDHPVVIPRYAGEEESAKLQEDMKVKEH
                     EDKDDASGRSSPCLSTTSQLSSMSMASGSVKMTSFAERKLQRLNSCETKSSTSSSQKT
                     TPDASESCPAPLTTWRQKREQSPGRHSKDPASLLASELVQLHMQLEEKRRAIEAQKKK
                     MEALSARQRLKLGKAAFLHVVKKGKADGAPQPLRPEHFTKEFTQHNGEDLDDGTCKTE
                     GFLVKEEQRDLSDAQDVAFVQLHKPRDPAALHDGEKHRMISTALLEDSVGEVDVNECD
                     LSIEKLNETISTLQQAILKISQQQEQLLMKSPTVPTPGTKNNCQDQKIKAPVHFVEPL
                     SPTGVPGHRKPPRLGQGRNSRSGRPAELKVPKDRQQGCSRSKTPTPSVETLPQSRSLP
                     PSTHPRSPSDPGGELPEKCLFDSYRLHDESNHRTFVLSSCKDANIVSEQVNFKEGLDT
                     SVKEAGLSSSTITGKEHTPVEEPLRSKASLIEVDLSDLKAPDEDGEVVGHESSVELGG
                     DSDQKPGVGFFFKDEQKAEDELAKKRAAFLLKQQRKAEEARARKQQLEAEVELKRDEA
                     RRKAEEDRLRKEEEKARRELIKQEYLRRKQQQALEEQGLGKPKSKPKKPRPKSVHREE
                     SYSDSGTKCSSTPDNLSQTHSGSSLSLASAATTEPESVYSGGTPSHRVESLEALPILS
                     RNPSRSTDRDWETASAASSLASVAEYTGPKLFKEPSSKSNKPIIHNAISHCCLAGKVN
                     EPHKNSILEELEKCDANHYIILFRDAGCQFRALYCYQPDTEEIYKLTGTGPKSITKKM
                     IDKLYKYSSDRKQFNLIPAKTMSVSVDALTIHNHLWQPKRPTVPKKTQTRK"
     exon            499..761
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            762..923
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1004
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1064
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1206
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1346
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1443
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            1444..1621
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            1622..1713
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            1714..1798
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            1799..4166
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            4167..4303
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            4304..4512
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            4513..4615
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            4616..4731
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            4732..4850
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     exon            4851..8041
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5582..5587
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /note="hexamer: CATAAA"
     polyA_site      5605
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /note="major polyA site"
     regulatory      7895..7900
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /note="hexamer: AATAAA"
     polyA_site      7915
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /note="major polyA site"
     regulatory      8018..8023
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /note="hexamer: AATAAA"
     polyA_site      8041
                     /gene="Camsap1"
                     /gene_synonym="9530003A05Rik; PRO2405"
                     /note="major polyA site"
ORIGIN      
        1 gcgcctgcgt gacgcggcgg cggcgcgtta gctcccaccc gttggccgcc gcctcagctg
       61 ccgcttctcc tgggccgcgc acgcgcctcc gccaccgccc ccggcccgtg ctcgcaccgc
      121 gcttgccccg cgcctgcccc gcgccttcct cggccggcgc ttgcccgccg ccgcctgccc
      181 ggcccgctcg gcgccttctc ggcctcggct cggcgcccgc agcatgcagc agcctgggtg
      241 gcggcggcgg ccgtgaagta agggccgtgc gcccgggcgg gcggcgcggg agggcggcgg
      301 cgtctttgtt gcggccgggc tgccgcggcc tttgtctgca gatggtggac gcgggcggtc
      361 gctgtgccgc cgaaggctgg aggaggatgg aggcgccccc ggagggcgcc gacctggtgc
      421 cgctggaccg ctacgacgcg gcgcgggcca agatcgccgc caacctgcag tggatctgtg
      481 cgaaggccta tggcctagac aacatccctg aggacctccg agacccgttt tacatcgacc
      541 agtatgagca ggagcacatt aagccacccg ttatcaagct tctcctgtcc agtgagctgt
      601 attgccgtgt ctgcagcctc atcctaaaag gggaccaggt ggctaccttg caaggacacc
      661 agtctgtcat ccaggccctg tcccggaagg gcatctatgt gatggagagt gatgataccc
      721 ctgtgacaga tgctgacctc agccaggcac ctattaagat gagtggccac atggcgatgg
      781 tggatgccct gatgatggcc tacactgtgg agatgatcag cattgagaag gtggtggcca
      841 gtgtcaagcg cttttctaca ttcagcgcct caaaagaact tccttatgac ctcgaggatg
      901 ccatggtatt ctggatcaat aaggtaaatc ttaaaatgag agagataaca gagaaagaag
      961 ttaaattaaa acagcagcca ctggaaagtc ccgctcatca aaagcctggc ctggagcatg
     1021 ctgtgatgca ctgcatgctg gaacctgtgg actttgcacg tgtggtccgt tatcggcgag
     1081 agcacctctc tgctaggcag tcaccctact tcccgttgtt ggaggacttg atgagagacg
     1141 gcagtgatgg cgctgctctc ttagcagtgg ttcactatta ttgcccagag cagatgaaac
     1201 tggatgatat ctgtctgaag gaggtgccat caatggctga cagcctctat aacatccgcc
     1261 ttctgaggga gttttccaac gagcatctga acaagtgttt ctatctcacg ctggaggata
     1321 tgctgtatgc ccccctagtg ctgaagccga acgttatggt ttttatcgct gagctcttct
     1381 ggtggtttga gaacgtcaaa ccagattttg ttcagccccg agatattcaa gagctgaagg
     1441 atgctaaaac agtgttacag cagaagagca gccggcctcc tgtccctatc tccaatgcaa
     1501 ccaaacgcag cttcctgggt agccctgctg ccatgagccc cgctgaccag ccaccatcca
     1561 cccagcctct tgctgaaggc agtcatcggt accacctcca ctcggaagaa cctgagtgtc
     1621 ttgggaaagg agcttccaca tttagtccgt cccatccttt gttgccactg agacagaaac
     1681 agcaaaaagt gtcacagaca gaggaaatcc ctgatcagcg gcacaggtcg aattctttaa
     1741 ctcgggttga tggtcagcca cgaggtgcaa taggagcatg gccagataaa aaaaacaggc
     1801 ctgtgtcaca gccaacatca tttgctctcc atcatgctgc aagttgtgat gtggatccca
     1861 gttctggtga cagtgtcagc ttagctcgct ctatcagcaa agatagcttg gcatctaaca
     1921 ttatccacct gaccccacag aaccagcccc atccctccgc tggaaagagc aatgggaaaa
     1981 gcctcctgag caatgtcaac attgaggatg aggacgagga gcttgtagcc atcatcagga
     2041 cagatgtgtc tcctccttcc ccacagatgc ccaggacctc acctcaggcc ccaggcctgg
     2101 tagcaagtat caggtctccc cagagacagg cagacacttt ggagagtaag cctgacagtt
     2161 tttacttaga acccctgatg ccagcagtac tccggccagc caaagagaag cagattacca
     2221 ctaaggaaga tgagcgtgga gaaggaaggc caaggaccat catggccaag aggcctagtg
     2281 agggctccca gcctatggta cgaaagaaag taagtggtgg ccatggcagt cgtgacctga
     2341 acagaacttt caccccaatt ccttgttcag aatttgctgc gagcattgat cttgcggagg
     2401 taggaccaca gtcagcagaa gctacagggg aaggacagcc tctggccctg ggtagatttg
     2461 atacattacc tcaggggcag gctgctgatg gtttctttct ccatgtaggc agggctgagg
     2521 aagatgaggg gaggtggtac gttggttcac aaagtcctag ctcccacgac tcagaaccct
     2581 ggaccatttt gaggcaagac tcggactctg atgtagtaga cgtagaggat acagagcagg
     2641 attttattgg tgaggaccac cctgtggtta tccccagata tgctggtgag gaagagtcag
     2701 ccaaactaca ggaggatatg aaagtgaagg aacatgaaga caaggatgat gccagcggcc
     2761 gctcaagccc gtgtctgagc accacttctc agctcagcag catgtccatg gccagtggaa
     2821 gtgtaaagat gaccagcttt gctgaaagga agctccagcg gctcaacagc tgtgagacca
     2881 agtccagcac cagcagctcc cagaagacca cccctgatgc atctgaaagc tgcccagccc
     2941 ctctgacaac gtggcgccag aagagggagc agagtccagg caggcacagc aaggaccctg
     3001 ccagcctgct ggcttctgag ctggtgcagc tgcacatgca gctggaggaa aagcgcagag
     3061 ctattgaagc ccagaagaaa aagatggagg cgctgtccgc acggcagcgt ctgaagctgg
     3121 gcaaggcagc ctttctgcat gtggtaaaga aagggaaggc tgatggtgcc ccacagccac
     3181 tgagacccga acacttcaca aaggaattca cacagcacaa tggggaggac ttggatgatg
     3241 gcacttgtaa aactgaaggg ttccttgtca aagaagagca gagagatctc agtgacgctc
     3301 aggatgtggc atttgtccag ctacataagc ccagggaccc agctgctctg catgatggag
     3361 agaagcacag aatgatttct acggccctcc tcgaggatag tgttggtgag gtagatgtga
     3421 acgagtgtga cctgtccatt gagaagctca atgagaccat cagtacattg cagcaggcta
     3481 tactgaagat ctcccagcag caagagcagc ttctcatgaa gtcccccaca gtgccaacac
     3541 cgggcactaa aaataactgc caggaccaaa aaataaaggc cccagtccac tttgttgagc
     3601 cactctctcc aactggcgtg cctggccacc gcaaaccacc acggcttggc cagggccgga
     3661 attcccgctc aggaaggccg gctgaactga aggttccaaa agacaggcag cagggttgtt
     3721 ctcggagcaa aaccccaaca cccagtgtgg agacactccc acagtcaagg tctttacctc
     3781 caagtaccca tccacggtca ccctccgacc caggcgggga actccctgag aagtgtctct
     3841 tcgacagtta taggctccat gatgagagta accatcggac atttgttctg tcctcttgca
     3901 aagatgcaaa cattgtatca gaacaggtga actttaaaga gggtctagat acaagtgtga
     3961 aagaggcagg gctgagctcc tctaccatca caggcaaaga acatactcca gtggaagagc
     4021 cgctgaggag caaggccagc ctcattgagg tagacctctc tgacctgaag gcccctgatg
     4081 aggatggaga ggtggttggc catgagagct cggtggagct tggtggagat agtgaccaga
     4141 agcctggggt tggtttcttc ttcaaggatg aacagaaagc agaagatgag cttgctaaga
     4201 agcgggcagc cttccttttg aaacagcagc gcaaggctga agaggctcgt gcgcgcaagc
     4261 agcagctgga ggcagaagtg gagctcaagc gagatgaagc ccggcgtaag gctgaagagg
     4321 atcgactacg gaaggaggag gagaaggcaa ggcgagagct cattaaacag gaatacttac
     4381 ggaggaagca gcagcaggcc ttggaggagc aaggacttgg caaacctaaa tcaaagccta
     4441 aaaagcctcg gccaaagtca gttcaccggg aagagtctta cagcgactct ggcaccaagt
     4501 gctcttctac cccagataac ttgagccaaa ctcactctgg ctccagccta tccttggcat
     4561 ctgcagcaac aacagaacct gagagtgttt attcgggggg cacaccttct caccgagttg
     4621 aatcactgga agctttacct atcctgagcc gcaaccccag tcggagcaca gaccgagact
     4681 gggagactgc atcagcagct tcctctttgg cctctgtggc tgagtacaca ggtcctaaac
     4741 tctttaagga gcccagtagc aaatcaaaca aaccaattat tcacaatgcc atctcccact
     4801 gctgtctggc tggaaaagtg aatgagcctc acaagaattc aatattggag gagctggaga
     4861 agtgtgatgc caaccactat attattctgt tccgagatgc gggctgccag ttcagggcac
     4921 tttactgcta ccaacccgac actgaagaaa tctacaaact cactggcacg gggccaaaaa
     4981 gcatcaccaa gaagatgatt gacaaactat ataaatacag ctcagaccga aagcagttta
     5041 acctgatccc agccaagacc atgtcagtca gcgtggatgc actcacgatc cataaccact
     5101 tgtggcagcc caagcggccc acggtgccaa agaagaccca gactcgtaag tgaccatggc
     5161 aaccaggact ctgagaggtt gtgctgacgg gatccctatt tattattttc atctacttgg
     5221 tacgaagttg atgagccatg gacagttttc tacagcggtt cctagagaac agagaagatg
     5281 ctctctcccc tgcacacatg gatgctgggc atgacatatg caggagtgag tcctgtgctt
     5341 tcatgggcat ggctgctgtg gccctgctga ccactgagat cctcagaata agggacacca
     5401 tggagtgaga tcctggcctg tgggcccctc acttgaagtt cttcagaata agttaaatgt
     5461 gatctgctct ctggcctccc ttcacccctg tgcacattgc ctgatgcccc atgttggcca
     5521 gctgtaatcg tgcgtgatta tagggccaag gctcattcgg gtcagggtgt ttgaatgtct
     5581 tcataaaagg agttcgtatg ggaaatcttt ttcattttag aaattgtata atatttattg
     5641 actgtgtcta ctgccaacct ttatatccag ttctaagatt ctgaaaaaaa gaaaagaaaa
     5701 aaaaaaacct gttccttgct gctcagaaaa agtttactga aaatgtcagt tcactaaaag
     5761 cactgaaatc ggtaaagttt gtcttctgct aaaatgacgt ttacatatgt ggagtgagta
     5821 tttctgccac acagttgggg gctgtgggta ctgctagctg atgctggcct cattggaagc
     5881 cggcagctaa gccggcttag ccaccactgg ttaggtctgg ggaatgtgct ggcatgttca
     5941 ctctgataaa ggcagatttt ggtatagtag cgtactttcc acccttggct gccggttcct
     6001 ttgtggtgct gtgaaggcct ggcttaccta ccacggttct tgcttctgga ggaacagcgt
     6061 gctcagtgca gtgtgcagtc tcaggtgagg tgggtaattc tgctttttgc ctcttttaaa
     6121 acttggtggt tatttgcggt tatttcagaa tggtgtagct gctttgggtc tcttccccgc
     6181 tggcccctgt ggcagctgcc tgcctcagaa caggcgttcc tggggagcag aggtgcccca
     6241 gcgatggatc agctatgtga agaccctgga gccacttgta gttttgcaca tttctttttg
     6301 agagtgttac ttgaatctgt cttaactgca ggagagactt gaagatcata gagggaactc
     6361 agacatctta gtgttagcgc tagcagtgtc atgtagacag aggaaaggag catgggacag
     6421 aacgccggag gcgtgaggcg aggtcttgtc ttctcttcct tggtgactgt gtatccagtc
     6481 aggggtggcg ctgtgctgta tgagcattaa agtctgtggc cacctgtcac tggatgccct
     6541 gtgtgtcttc atttctcact gtgcacttga tgttaccata tttattttaa gagagcacta
     6601 aaatataata aagtaatgag ctggctttct gttaaccatg tgtgtggttg tcacaactcc
     6661 ttctgctgac agtgtcccac atcttctggc ttcagggcag ctgcgcatga cttttgggtt
     6721 acctaggaat ttatttttca tgaagagttg gaagacctgg tgtagagcag gaagttgcat
     6781 ttctgctcga cttttaatac ggtgacttgg catgtggcct gtcctgaagg ctgtctcaga
     6841 acgcagggtc tgcatgtgaa gtacagtgcc agtgtctcaa ggccgggctg tggaggccat
     6901 gtggcttgat ggctcagaag cactcgtgcc ttctgtgttc catgacacag aagtagtttt
     6961 gatttttttt ttaattagga agtttccggt acaggatttt gtggtggtga tctggagcct
     7021 ccagggtgtg ggtacactgt cttgaccaac tgtgctggga aggctactca gcttttcggg
     7081 cagaaagtgc caagaaattg aatacatgac gactcatgca gctcattcct tagtaacaac
     7141 agaccccccc gaggagccca ggtcggttgg cattaaaaat atttctcagc cgggcggtgg
     7201 tggcgcacgc ctttaatcca agcacttggg aggcagagac aggcggattt ctgagtttga
     7261 ggccagcctg atctacaaag tgagttccag gacagccagg actacacaga gaaaccctgt
     7321 ctcgaaaaaa taaaaaaaaa aaatctcaga actagatgtg caggtctaca tgtctgtgtc
     7381 gatgtgggat gtacctgtgt gtgcgtatat gagtatgtgc acacaaacat gtgcatatgg
     7441 cctgtgtaca cgtgtgtatg catgccaaag atagcgtttc cagtgtgacc ttttgacctg
     7501 gtattctcgg tgtgttcctg caatacaatc tccaatcaga cttttaaggc ccagactgct
     7561 tcaggcaaca ttgaaaagtg gcataataca aaatttactt ctagattgtt tgaaactatg
     7621 gttgttactt ggaagaagaa agtgttaaaa gtccattttt cttgttgaaa gttaatcaac
     7681 ttgagtaaac ctttatagat tggtgctggt ttacctagtg aaatggcttt gatcttggtt
     7741 acctgagcct attggtgatt tcattctatc tgtgtccagt accacatgtg taaagccagt
     7801 tctaactcct gttttgtgac tatggccaag tcacaagccc caactgggaa cgagccatgc
     7861 ccagcatcct cttgtttctc actgattcct tggcaataaa cttgtacctt gctgactcag
     7921 ggtcttcctg gtgtctgagg tgcactctgg aggtgctttt ggtatctggt atcactggtg
     7981 ttctgagctt tgtgttgctg tgataaatga aaaccataat aaaagccacg accaaataca
     8041 a
//
