LOCUS       NM_144817               2467 bp    mRNA    linear   ROD 21-DEC-2022
DEFINITION  Mus musculus calcium/calmodulin-dependent protein kinase I gamma
            (Camk1g), mRNA.
ACCESSION   NM_144817
VERSION     NM_144817.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2467)
  AUTHORS   Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S,
            Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ,
            Jones AR, Amaral DG, Sestan N, Gage FH and Lein ES.
  TITLE     Conserved molecular signatures of neurogenesis in the hippocampal
            subgranular zone of rodents and primates
  JOURNAL   Development 140 (22), 4633-4644 (2013)
   PUBMED   24154525
REFERENCE   2  (bases 1 to 2467)
  AUTHORS   Pang ZP, Xu W, Cao P and Sudhof TC.
  TITLE     Calmodulin suppresses synaptotagmin-2 transcription in cortical
            neurons
  JOURNAL   J Biol Chem 285 (44), 33930-33939 (2010)
   PUBMED   20729199
  REMARK    GeneRIF: Calmodulin suppresses synaptotagmin-2 transcription in
            cortical neurons
REFERENCE   3  (bases 1 to 2467)
  AUTHORS   Ageta-Ishihara N, Takemoto-Kimura S, Nonaka M, Adachi-Morishima A,
            Suzuki K, Kamijo S, Fujii H, Mano T, Blaeser F, Chatila TA, Mizuno
            H, Hirano T, Tagawa Y, Okuno H and Bito H.
  TITLE     Control of cortical axon elongation by a GABA-driven
            Ca2+/calmodulin-dependent protein kinase cascade
  JOURNAL   J Neurosci 29 (43), 13720-13729 (2009)
   PUBMED   19864584
REFERENCE   4  (bases 1 to 2467)
  AUTHORS   Takemoto-Kimura S, Ageta-Ishihara N, Nonaka M, Adachi-Morishima A,
            Mano T, Okamura M, Fujii H, Fuse T, Hoshino M, Suzuki S, Kojima M,
            Mishina M, Okuno H and Bito H.
  TITLE     Regulation of dendritogenesis via a lipid-raft-associated
            Ca2+/calmodulin-dependent protein kinase CLICK-III/CaMKIgamma
  JOURNAL   Neuron 54 (5), 755-770 (2007)
   PUBMED   17553424
  REMARK    GeneRIF: CL3 may represent a key element in the Ca(2+)-dependent
            and lipid-raft-delineated switch that turns on extrinsic
            activity-regulated dendrite formation in developing cortical
            neurons.
REFERENCE   5  (bases 1 to 2467)
  AUTHORS   Kamata A, Sakagami H, Tokumitsu H, Owada Y, Fukunaga K and Kondo H.
  TITLE     Spatiotemporal expression of four isoforms of
            Ca2+/calmodulin-dependent protein kinase I in brain and its
            possible roles in hippocampal dendritic growth
  JOURNAL   Neurosci Res 57 (1), 86-97 (2007)
   PUBMED   17056143
REFERENCE   6  (bases 1 to 2467)
  AUTHORS   Chen Y, Perry D, Boackle SA, Sobel ES, Molina H, Croker BP and
            Morel L.
  TITLE     Several genes contribute to the production of autoreactive B and T
            cells in the murine lupus susceptibility locus Sle1c
  JOURNAL   J Immunol 175 (2), 1080-1089 (2005)
   PUBMED   16002709
REFERENCE   7  (bases 1 to 2467)
  AUTHORS   Frederikse PH, Yun E, Kao HT, Zigler JS Jr, Sun Q and Qazi AS.
  TITLE     Synapsin and synaptic vesicle protein expression during embryonic
            and post-natal lens fiber cell differentiation
  JOURNAL   Mol Vis 10, 794-804 (2004)
   PUBMED   15529118
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 2467)
  AUTHORS   Takada H, Chen NJ, Mirtsos C, Suzuki S, Suzuki N, Wakeham A, Mak TW
            and Yeh WC.
  TITLE     Role of SODD in regulation of tumor necrosis factor responses
  JOURNAL   Mol Cell Biol 23 (11), 4026-4033 (2003)
   PUBMED   12748303
REFERENCE   9  (bases 1 to 2467)
  AUTHORS   Takemoto-Kimura S, Terai H, Takamoto M, Ohmae S, Kikumura S, Segi
            E, Arakawa Y, Furuyashiki T, Narumiya S and Bito H.
  TITLE     Molecular cloning and characterization of CLICK-III/CaMKIgamma, a
            novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein
            kinase (CaMK)
  JOURNAL   J Biol Chem 278 (20), 18597-18605 (2003)
   PUBMED   12637513
  REMARK    GeneRIF: CLICK-III/CaMKIgamma is a novel membrane-anchored neuronal
            Ca2+/calmodulin-dependent protein kinase (CaMK).
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY730299.1 and BC021840.1.
            
            [WARNING] On May 18, 2023 this sequence was replaced by
            NM_144817.3.
            
            On Apr 15, 2006 this sequence version replaced NM_144817.1.
            
            Sequence Note: This sequence has been modified as follows: removed
            35 bp suspected to be vector contamination from the 3' end.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC021840.1, SRR1660813.162685.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-51                BY730299.1         2-52
            52-2467             BC021840.1         1-2416
FEATURES             Location/Qualifiers
     source          1..2467
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 97.74 cM"
     gene            1..2467
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /note="calcium/calmodulin-dependent protein kinase I
                     gamma"
                     /db_xref="GeneID:215303"
                     /db_xref="MGI:MGI:2388073"
     exon            1..108
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
     exon            109..229
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
     CDS             138..1571
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /EC_number="2.7.11.17"
                     /note="CLICK III; caMKIG; caMKI gamma; caM-KI gamma; caM
                     kinase IG; caM kinase I gamma; caMK-like CREB kinase III"
                     /codon_start=1
                     /product="calcium/calmodulin-dependent protein kinase type
                     1G"
                     /protein_id="NP_659066.1"
                     /db_xref="CCDS:CCDS15638.1"
                     /db_xref="GeneID:215303"
                     /db_xref="MGI:MGI:2388073"
                     /translation="MGRKEEEDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRV
                     TGKLFALKCIKKSPAFRDSSLENEIAVLKRIKHENIVTLEDIYESTTHYYLVMQLVSG
                     GELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKI
                     MITDFGLSKMEQNGVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPP
                     FYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALRHPW
                     IDGNTALHRDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNLHSPSVRQEVE
                     NRPPVSPAPEVSRPDSHDSSITEAPILDPSTPLPALTRLPCSHSSRPSAPSGGRSLNC
                     LVNGSLRISSSLVPMQQGPLATGPCGCCSSCLNIGNKGKSSYCSEPTLFRKANKKQNF
                     KSEVMVPVKAGGSTHCRGGQTGVCLVM"
     exon            230..358
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
     exon            359..433
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
     exon            434..572
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
     exon            573..696
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
     exon            697..772
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
     exon            773..885
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
     exon            886..964
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
     exon            965..1052
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..1480
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1596
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..2453
                     /gene="Camk1g"
                     /gene_synonym="CaMKIgamma; CLICK-III"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aattgggttt attgttaaag cactggggca gctaatcctc acagacctgt aggagcaggc
       61 ttgctggcca agatcacaga ctggagcacc tttcttgtga gcccctggct tctcaggcag
      121 cttcaactct ggaggacatg gggcgtaagg aggaggagga ctgcagttcc tggaagaaac
      181 agaccaccaa catcaggaaa accttcatct tcatggaagt gctgggatca ggagctttct
      241 cagaggtgtt cctggtgaag caaagagtga ctgggaaact ctttgctctg aaatgtatca
      301 agaagtcacc agccttccgg gacagcagcc tagagaatga gatcgctgtg ttgaaaagga
      361 tcaagcatga gaacattgtg accctggagg acatctatga gagcaccacc cactactacc
      421 tggtcatgca gcttgtttct ggaggtgagc tttttgaccg gatcctagag cgtggtgtct
      481 acacagaaaa ggatgccagc ctggtcatcc agcaggtctt gtctgcggtg aaataccttc
      541 atgagaatgg catcgtccac agagatctaa agcctgaaaa cctgctgtac ctcacccctg
      601 aggagaactc caagatcatg atcactgact ttggtctatc caagatggag cagaatggag
      661 tcatgtccac agcttgtggg accccaggct acgtggctcc agaagtgctg gcccagaagc
      721 cctacagtaa ggctgtggac tgctggtcca ttggtgtcat cacatacata ctgctgtgtg
      781 gctatccccc tttctatgaa gaaacagaat caaagctttt tgagaagatc aaagagggtt
      841 actacgagtt tgagtctccg ttctgggatg acatttctga gtcagccaag gattttattt
      901 gccatctgct ggagaaggac ccaaacgaac ggtacacctg cgagaaagcc ctcagacacc
      961 cctggattga tggaaacaca gccctgcacc gggacatcta tccatctgtc agcctccaga
     1021 ttcagaagaa ctttgccaag agcaagtgga ggcaagcctt caacgcagct gcggtggtgc
     1081 atcacatgag gaaactgcac atgaacctgc acagccccag tgtccgccaa gaggtggaga
     1141 acaggccacc tgtgtcccct gctcctgaag tctccagacc agactcccat gacagctcca
     1201 tcacagaggc ccccatcctg gacccaagca caccccttcc tgcactgacc cgactaccct
     1261 gctcacacag ctcccggcct tcagctccca gtggtggccg ctcactcaac tgcctggtca
     1321 acggctccct gcgcatcagc agtagcctag tgcccatgca acagggcccc ctagccacgg
     1381 ggccctgtgg ctgctgctcc agctgtctaa atattgggaa caagggaaag tcttcctact
     1441 gctctgagcc taccctcttc agaaaggcca ataaaaaaca gaacttcaag tcagaggtca
     1501 tggtaccagt gaaggctggt ggcagcaccc actgccgggg tgggcagact ggggtgtgtc
     1561 tcgttatgtg atcccaggag cccatgtggt tttcaggaga cattcctggc tcttctctgc
     1621 ctctctgagc tggcatctgc cctgaggaag gggggcagtg gaatagagat agccaaagca
     1681 gctggtctga ggcagtaggg ctgttgctgc ctgggcagac actcacagga agtccagagg
     1741 agccagcccc aatcttggac gttctctgag gccacaagca ggatgagtgg cctgcctgcc
     1801 tccagcatcc cagcctccag gtctcccgac ctgcccattc ccttccccac atcatacgtg
     1861 cagtggctcc atgcagtgtc catagatagt gctcatctgg gtccgtgttg tttgttgtga
     1921 aaagctttat gggctggcca ggctgtgtca ctttcttcaa gcaaagccat atggagtcta
     1981 actcagactc cctgctctgc agactcgctc ctgcctatct ggcctcacgg ccagactgga
     2041 cccattatca tagtacctgc ctattcgcat gaatgccagg ctgcaccagg ggcctgggag
     2101 cactcacaac tccagtccgt tcctccagga ttagcttccc actgcacgga gacccaggcc
     2161 actccaaagc tctccttgcc tccatctcac agcagtgccc ccatcctcca tggtggacta
     2221 gagaaagctg tgactatgga ctgtgagcct tctctccctg ctggccacac acctcatata
     2281 tccctaatta aggattcggg gactatttcc atgtcatcca ggtctcctgc ctctggctcc
     2341 ctcccttccc ctgaaagtca ggtgcattgt tctgtctctc tgtgttcttg cctcataccc
     2401 tcaagcttcg tgctctgtgt tgtgctcaaa taaaatggac atatttttct ctaaaaaaaa
     2461 aaaaaaa
//
