LOCUS       NM_001271018            2029 bp    mRNA    linear   ROD 26-SEP-2023
DEFINITION  Mus musculus calcium binding and coiled-coil domain 2 (Calcoco2),
            mRNA.
ACCESSION   NM_001271018
VERSION     NM_001271018.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2029)
  AUTHORS   Sun M, Zhang W, Bi Y, Xu H, Abudureyimu M, Peng H, Zhang Y and Ren
            J.
  TITLE     NDP52 Protects Against Myocardial Infarction-Provoked Cardiac
            Anomalies Through Promoting Autophagosome-Lysosome Fusion via
            Recruiting TBK1 and RAB7
  JOURNAL   Antioxid Redox Signal 36 (16-18), 1119-1135 (2022)
   PUBMED   34382418
  REMARK    GeneRIF: NDP52 Protects Against Myocardial Infarction-Provoked
            Cardiac Anomalies Through Promoting Autophagosome-Lysosome Fusion
            via Recruiting TBK1 and RAB7.
REFERENCE   2  (bases 1 to 2029)
  AUTHORS   Ingham NJ, Pearson SA, Vancollie VE, Rook V, Lewis MA, Chen J,
            Buniello A, Martelletti E, Preite L, Lam CC, Weiss FD, Powis Z,
            Suwannarat P, Lelliott CJ, Dawson SJ, White JK and Steel KP.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2029)
  AUTHORS   Kim S, Lee D, Song JC, Cho SJ, Yun SM, Koh YH, Song J, Johnson GV
            and Jo C.
  TITLE     NDP52 associates with phosphorylated tau in brains of an Alzheimer
            disease mouse model
  JOURNAL   Biochem Biophys Res Commun 454 (1), 196-201 (2014)
   PUBMED   25450380
  REMARK    GeneRIF: expression and association of NDP52 with
            autophagy-regulated gene proteins including LC3, as well as
            phosphorylated tau and amyloid-beta in brains of an Alzheimer
            disease model
REFERENCE   4  (bases 1 to 2029)
  AUTHORS   Cosme-Cruz R, Martinez FP, Perez KJ and Tang Q.
  TITLE     H2B homology region of major immediate-early protein 1 is essential
            for murine cytomegalovirus to disrupt nuclear domain 10, but is not
            important for viral replication in cell culture
  JOURNAL   J Gen Virol 92 (Pt 9), 2006-2019 (2011)
   PUBMED   21632568
  REMARK    GeneRIF: The authors conclude that the dispersion of ND10 by major
            immediate-early protein 1 (IE1) appears not to be important for
            murine cytomegalovirus replication in a mouse-cell culture.
REFERENCE   5  (bases 1 to 2029)
  AUTHORS   Cosme RC, Martinez FP and Tang Q.
  TITLE     Functional interaction of nuclear domain 10 and its components with
            cytomegalovirus after infections: cross-species host cells versus
            native cells
  JOURNAL   PLoS One 6 (4), e19187 (2011)
   PUBMED   21552525
  REMARK    GeneRIF: ND10 and ND10 components might be important defensive
            factors against the CMV cross-species infection
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2029)
  AUTHORS   Bortvin A, Eggan K, Skaletsky H, Akutsu H, Berry DL, Yanagimachi R,
            Page DC and Jaenisch R.
  TITLE     Incomplete reactivation of Oct4-related genes in mouse embryos
            cloned from somatic nuclei
  JOURNAL   Development 130 (8), 1673-1680 (2003)
   PUBMED   12620990
REFERENCE   7  (bases 1 to 2029)
  AUTHORS   Mohlke KL, Purkayastha AA, Westrick RJ and Ginsburg D.
  TITLE     Comparative mapping of distal murine chromosome 11 and human
            17q21.3 in a region containing a modifying locus for murine plasma
            von Willebrand factor level
  JOURNAL   Genomics 54 (1), 19-30 (1998)
   PUBMED   9806826
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK145542.1, AL603682.36, AK167172.1 and BB730060.1.
            
            [WARNING] On Jan 26, 2024 this sequence was replaced by
            NM_001271018.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK145542.1, BY735862.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-813               AK145542.1         2-814
            814-814             AL603682.36        124411-124411       c
            815-1571            AK145542.1         816-1572
            1572-1619           AK167172.1         1279-1326
            1620-2029           BB730060.1         63-472
FEATURES             Location/Qualifiers
     source          1..2029
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 59.4 cM"
     gene            1..2029
                     /gene="Calcoco2"
                     /gene_synonym="2410154J16Rik; Ndp52; Ndp52l1"
                     /note="calcium binding and coiled-coil domain 2"
                     /db_xref="GeneID:76815"
                     /db_xref="MGI:MGI:1343177"
     exon            1..26
                     /gene="Calcoco2"
                     /gene_synonym="2410154J16Rik; Ndp52; Ndp52l1"
                     /inference="alignment:Splign:2.1.0"
     exon            27..200
                     /gene="Calcoco2"
                     /gene_synonym="2410154J16Rik; Ndp52; Ndp52l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             36..1031
                     /gene="Calcoco2"
                     /gene_synonym="2410154J16Rik; Ndp52; Ndp52l1"
                     /note="nuclear domain 10 protein 52 like 1; nuclear domain
                     10 protein NDP52"
                     /codon_start=1
                     /product="calcium-binding and coiled-coil
                     domain-containing protein 2"
                     /protein_id="NP_001257947.1"
                     /db_xref="CCDS:CCDS59567.1"
                     /db_xref="GeneID:76815"
                     /db_xref="MGI:MGI:1343177"
                     /translation="MDQCPIPTLLEHGNFSQVLFNNVEKFYAPRGDIMCYYTLTEKFI
                     PRRKDWIGIFKVGWKTTQEYYTFMWAPLPKDQNKDSATQQEIQFKAYYLPKDVERYQF
                     CYVDEDGLVRGTSVPFQFCPDPDEDIMVVINKEKVEEMEQLSEELYQQNQELKDKYAD
                     LHEQLQRKQVALEATQRVNKTLEHKVEEKASWEKEKASWEEEKASWEEEKASWEEEKA
                     SWEEEKASWEEEKASWEEEKASWEEEKASWEEEKASWEEEKASWEEEKASWEEEKASW
                     EEEKASWEEEKASWEKEKASWEEEKASWEKEKAPWEVEKAPWKEVKAYWWNDLHR"
     exon            201..303
                     /gene="Calcoco2"
                     /gene_synonym="2410154J16Rik; Ndp52; Ndp52l1"
                     /inference="alignment:Splign:2.1.0"
     exon            304..437
                     /gene="Calcoco2"
                     /gene_synonym="2410154J16Rik; Ndp52; Ndp52l1"
                     /inference="alignment:Splign:2.1.0"
     exon            438..542
                     /gene="Calcoco2"
                     /gene_synonym="2410154J16Rik; Ndp52; Ndp52l1"
                     /inference="alignment:Splign:2.1.0"
     exon            543..2029
                     /gene="Calcoco2"
                     /gene_synonym="2410154J16Rik; Ndp52; Ndp52l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctagtgctg ctggctgctg ttcctggact tcaccatgga ccagtgcccc atacctacct
       61 tgctggaaca tggcaacttc tctcaggtcc tgtttaacaa tgtggagaag ttctatgctc
      121 ctagaggaga tatcatgtgc tattacaccc tcactgaaaa gttcatccct cgacgcaagg
      181 actggattgg catctttaaa gtagggtgga agaccactca ggagtattat accttcatgt
      241 gggctccctt gccaaaagac caaaacaagg attcagccac acagcaggaa atccaattca
      301 aagcttatta ccttcccaag gatgtggagc gctaccagtt ctgctatgtg gatgaagatg
      361 gtttagtccg gggaacaagt gtccctttcc agttttgtcc agaccctgac gaggacataa
      421 tggttgttat caataaggaa aaggtagaag agatggaaca gctcagtgag gagctttacc
      481 aacaaaacca ggagctgaaa gacaagtacg ctgacctcca tgagcagcta cagaggaagc
      541 aggtggcact ggaagcaaca cagagggtca ataagacctt agaacacaaa gtggaagaga
      601 aggcctcctg ggagaaagag aaggcctcct gggaggaaga gaaggcctcc tgggaggaag
      661 agaaggcctc ctgggaggaa gagaaggcct cctgggagga agagaaggcc tcctgggagg
      721 aagagaaggc ctcctgggag gaagagaagg cctcctggga ggaagagaag gcctcctggg
      781 aggaagagaa ggcctcctgg gaggaagaga aggcctcctg ggaggaagag aaggcctcct
      841 gggaggaaga gaaggcctcc tgggaggaag agaaggcctc ctgggaggaa gagaaggcct
      901 cctgggagaa agagaaggcc tcctgggagg aagagaaggc ctcctgggag aaagagaagg
      961 ccccctggga ggtagagaag gccccctgga aggaagtgaa ggcctattgg tggaatgatc
     1021 tgcaccggtg agtgggggaa gggccactca ctgttagcac tgcctgttct ggtttggtat
     1081 gattgcacat cccagactga ggaccagaag tttaaggcca tccttagcta cacagtgaat
     1141 ctgaggccag cgtaggctac atgatggcct gtcccaaaac aaaacaaaga aacccctgtc
     1201 tcaaaaggac tcagccaagt ggtcgtgcac acctttaatc tcagcactag ggaagctggg
     1261 acagaaggat tgccccagtt cgggataaat agtagctggc cagacagcta tatagcaaga
     1321 ccctatttca gaaaccaaag aaaggagaaa aaattgattg ttaaatgtgg ttgtatgatt
     1381 ttaaacccac tagaagatgt actttgatat gtgtgtgtat cctgggtacc ctctgagctc
     1441 agagagggta tcaggtctct gaaactggag ttacagagtt atgagctagg taccaaacct
     1501 gagtcctgtg caagagcatc aagtgctctt cacttttgag ccatccctcc aaccataaat
     1561 taactttaca ttcatacatt ttgtgctgtg ttgattttat aaagtcatat ttgtatttta
     1621 tgtatgtgag tacactatca ctgttgctgt ccaaacacac cagaagagga catccggatc
     1681 cctttagatg gttgtgagcc accatgtggc tgctgggaat tgaactcagg acctctggaa
     1741 gagcagccag tgctcttaac cactgagcca tctctccagt ccaaagtcat atttttaaaa
     1801 aaggggcggg gggtcggggg gaggctcaca gtgggagctt cacctgcaga ggaagttcat
     1861 ctcaggaact tggataaatg ttacttctcc cagtactgag ttgaggtgtc cgtgtatctt
     1921 ggactggtga cagcaacaac caccatttgg ccaggagcat gagtggtctc tgttggggaa
     1981 tttctattct gtggagatgg atgtagccaa taaaaaggag ttacaaccc
//
