LOCUS       NM_026192               2840 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus calcium binding and coiled coil domain 1 (Calcoco1),
            mRNA.
ACCESSION   NM_026192
VERSION     NM_026192.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2840)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2840)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2840)
  AUTHORS   Stefely,J.A., Zhang,Y., Freiberger,E.C., Kwiecien,N.W.,
            Thomas,H.E., Davis,A.M., Lowry,N.D., Vincent,C.E., Shishkova,E.,
            Clark,N.A., Medvedovic,M., Coon,J.J., Pagliarini,D.J. and
            Mercer,C.A.
  TITLE     Mass spectrometry proteomics reveals a function for mammalian
            CALCOCO1 in MTOR-regulated selective autophagy
  JOURNAL   Autophagy 16 (12), 2219-2237 (2020)
   PUBMED   31971854
  REMARK    GeneRIF: Mass spectrometry proteomics reveals a function for
            mammalian CALCOCO1 in MTOR-regulated selective autophagy.
REFERENCE   4  (bases 1 to 2840)
  AUTHORS   Nthiga,T.M., Kumar Shrestha,B., Sjottem,E., Bruun,J.A., Bowitz
            Larsen,K., Bhujabal,Z., Lamark,T. and Johansen,T.
  TITLE     CALCOCO1 acts with VAMP-associated proteins to mediate ER-phagy
  JOURNAL   EMBO J 39 (15), e103649 (2020)
   PUBMED   32525583
  REMARK    GeneRIF: CALCOCO1 acts with VAMP-associated proteins to mediate
            ER-phagy.
REFERENCE   5  (bases 1 to 2840)
  AUTHORS   Mizuta,S., Minami,T., Fujita,H., Kaminaga,C., Matsui,K., Ishino,R.,
            Fujita,A., Oda,K., Kawai,A., Hasegawa,N., Urahama,N., Roeder,R.G.
            and Ito,M.
  TITLE     CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a
            novel pathway for GATA1 function
  JOURNAL   Genes Cells 19 (1), 28-51 (2014)
   PUBMED   24245781
  REMARK    GeneRIF: CoCoA and CCAR1 appear to relay the GATA1 signal to MED1,
            and multiple modes of the GATA1-MED1 axis may help to fine-tune
            GATA1 function during GATA1-mediated homeostasis events.
            Erratum:[Genes Cells. 2023 Jan;28(1):78. doi: 10.1111/gtc.12991..
            PMID: 36647803]
REFERENCE   6  (bases 1 to 2840)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 2840)
  AUTHORS   Yang,C.K., Kim,J.H., Li,H. and Stallcup,M.R.
  TITLE     Differential use of functional domains by coiled-coil coactivator
            in its synergistic coactivator function with beta-catenin or GRIP1
  JOURNAL   J Biol Chem 281 (6), 3389-3397 (2006)
   PUBMED   16344550
REFERENCE   8  (bases 1 to 2840)
  AUTHORS   Kim,J.H. and Stallcup,M.R.
  TITLE     Role of the coiled-coil coactivator (CoCoA) in aryl hydrocarbon
            receptor-mediated transcription
  JOURNAL   J Biol Chem 279 (48), 49842-49848 (2004)
   PUBMED   15383530
REFERENCE   9  (bases 1 to 2840)
  AUTHORS   Kim,J.H., Li,H. and Stallcup,M.R.
  TITLE     CoCoA, a nuclear receptor coactivator which acts through an
            N-terminal activation domain of p160 coactivators
  JOURNAL   Mol Cell 12 (6), 1537-1549 (2003)
   PUBMED   14690606
REFERENCE   10 (bases 1 to 2840)
  AUTHORS   Kambouris,M., Triarhou,L.C., Dlouhy,S.R., Sangameswaran,L., Luo,F.,
            Ghetti,B. and Hodes,M.E.
  TITLE     Novel cDNA clones obtained by antibody screening of a mouse
            cerebellar cDNA expression library
  JOURNAL   Brain Res Mol Brain Res 25 (3-4), 183-191 (1994)
   PUBMED   7808216
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124532.4, AK035598.1, AC123870.3 and BC054783.1.
            
            On Jun 19, 2010 this sequence version replaced NM_026192.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC054783.1, AK007393.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                AC124532.4         109816-109904
            90-545              AK035598.1         2-457
            546-546             AC123870.3         2175-2175
            547-2822            AK035598.1         459-2734
            2823-2840           BC054783.1         2717-2734
FEATURES             Location/Qualifiers
     source          1..2840
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 57.81 cM"
     gene            1..2840
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /note="calcium binding and coiled coil domain 1"
                     /db_xref="GeneID:67488"
                     /db_xref="MGI:MGI:1914738"
     exon            1..132
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            133..312
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     CDS             157..2232
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /note="coiled-coil transcriptional coactivator;
                     GRIP1-interacting protein; coiled-coil coactivator
                     protein; granule cell antiserum positive 11"
                     /codon_start=1
                     /product="calcium-binding and coiled-coil
                     domain-containing protein 1"
                     /protein_id="NP_080468.1"
                     /db_xref="CCDS:CCDS27889.1"
                     /db_xref="GeneID:67488"
                     /db_xref="MGI:MGI:1914738"
                     /translation="MEESSLSRAPSRGGVNFLNVARTYIPNTKVECHYTLPPGTMPSA
                     SDWIGIFKVEAACVRDYHTFVWSSVPESTTDGSPTHASVQFQASYLPKPGAQLYQFRY
                     VNRQGRVCGQSPPFQFREPRPMDELVTLEEADGGSDILLVVPKATVLQNQLDESQQER
                     NDLMQLKLQLEDQVTELRSRVQELEAALATARQEHSELTEQYKGLSRSHGELSEERDI
                     LSQQQGDHVARILELEDDIQTMSDKVLMKEVELDRVRDTVKALTREQEKLLRQLKEFQ
                     ADKEQSEAELQTVREENCCLNTELEEAKSRQEEQGAQVQRLKDKLAHMKDTLGQAQQK
                     VAELEPLKEQLRGVQELAASSQQKAALLGEELASAAGARDRTIAELHRSRLEVAEVNG
                     RLAELSLHMKEEKCQWSKERTGLLQSMEAEKDKILKLSAEILRLEKTVQEERTQSHVF
                     KTELAREKDSSLVQLSESKRELTELRSALRVLQKEKEQLQTEKQELLEYMRKLEARLE
                     KVADEKWTEDAATEDEEATAGLSCPASLTDSEDESPEDMRLPSYGLCESGNTSSSPPG
                     PREPSSLVVINQPAPIAPQFSGPGEASSSDSEAEDEKSVLMAAVQSGGEEASLLLPEL
                     GSAFYDVASAFTVSSLSEASPGVPANPPWKECPICKERFPAESDKDALEGHMDGHFFF
                     STQDPFTFE"
     exon            313..415
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            416..606
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            607..765
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            766..914
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1005
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1161
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1416
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            1417..1542
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            1543..1638
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            1639..1747
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            1748..1947
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            1948..2054
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     exon            2055..2824
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2801..2806
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /note="hexamer: AATATA"
     polyA_site      2824
                     /gene="Calcoco1"
                     /gene_synonym="1810009B06Rik; Cocoa; Gcap11; mKIAA1536"
                     /note="major polyA site"
ORIGIN      
        1 agacagtgtc gagtcataga agaaccacaa gccccagaag ctctcgcgtc actcttcccc
       61 tcccctccta tagtcggagt gctgtttttg ttgttggtga aaggtgaggg gaacagctga
      121 tccgtccgtg gggacatcag ccatcttgag gacagcatgg aagagtcatc actaagccgg
      181 gcaccatccc ggggtggagt caacttcctg aatgtggccc gcacctacat ccccaacacc
      241 aaggtggaat gtcactacac tttgcctccg ggtaccatgc ccagtgccag tgactggatt
      301 ggcattttta aggtggaagc tgcctgcgtt cgagattatc acacgttcgt gtggtcctca
      361 gtgccagaaa gtacaactga tggctccccc acccatgcca gtgtccaatt ccaagccagc
      421 tacctgccca aaccaggagc ccaactctac cagttccggt atgtgaaccg ccagggccgg
      481 gtgtgtgggc agagcccccc cttccagttc cgagagccaa ggcccatgga tgagctggtg
      541 accctggagg aggctgatgg aggctctgac atcctgttgg ttgtccctaa ggccaccgtg
      601 cttcagaacc agctggatga gagccagcag gagcggaatg acctgatgca gctgaagctg
      661 cagttggagg atcaggtgac agagctgagg agccgagtgc aggagctgga ggcagctctg
      721 gccacggcca ggcaggagca ttcggagctc accgagcagt acaaggggct ctcccggtcc
      781 catggggagc tctcagaaga gagggacatc ctgagccagc agcagggaga ccatgtggcc
      841 cgtatcctgg agttagagga tgacatccag accatgagtg acaaagtgct gatgaaggag
      901 gtggagctgg acagggttag agacacagtg aaggccctga cacgggaaca agagaagctc
      961 ctgagacagc tgaaggaatt ccaggcagac aaggagcaga gtgaggctga attacaaacg
     1021 gtccgagagg agaactgctg cttaaataca gagctggagg aggccaagag ccggcaagaa
     1081 gagcaaggtg ctcaggtcca gcgactgaag gacaagctgg cccacatgaa ggacaccctg
     1141 ggccaagccc agcagaaagt ggccgagctg gagcccctga aagagcagct ccgaggggtc
     1201 caggaacttg cagcctcaag ccagcagaaa gcggccctcc ttggggagga gttggccagt
     1261 gcagcaggag ctagagaccg aaccatagct gaactacacc gcagccgact ggaggtggct
     1321 gaagtcaacg gccgactggc tgagctcagc ctgcacatga aggaggaaaa gtgccagtgg
     1381 agcaaggagc ggacagggct gctgcagagc atggaggctg aaaaggataa gatcctgaag
     1441 ctgagtgcgg agatcctccg actggagaag acggtgcagg aggagaggac ccagagtcac
     1501 gtgttcaaga ctgagctggc ccgagaaaag gattctagcc tggtgcagtt gtcagagagt
     1561 aagcgggagc tcacagagct acggtcagcc ctccgtgtgc ttcagaagga gaaggagcag
     1621 ttgcagacgg agaaacagga actgctggag tacatgagga agctggaggc ccgcctggag
     1681 aaggtggcgg atgagaagtg gaccgaagat gctgccacag aggacgagga agccactgct
     1741 gggctgagct gccctgcatc tctgacagac tcagaggacg agtccccaga agacatgcgg
     1801 ctcccatcct atggcttgtg tgagagtgga aacacaagct cctctcctcc tgggcctcgg
     1861 gagccttctt ctcttgttgt catcaaccaa ccagcaccca ttgctcccca gttctcaggt
     1921 ccaggggagg ccagcagctc agactcggag gctgaagatg agaagtcagt cctgatggca
     1981 gcggtgcaga gtgggggcga ggaagccagc ctcctgcttc ctgagctcgg cagtgccttc
     2041 tatgacgtgg ccagtgcttt tacagtgagt tccctgtcag aggccagccc tggggtccca
     2101 gccaaccctc catggaagga gtgtcccatc tgcaaggagc gcttccctgc tgagagtgac
     2161 aaggacgccc tagagggcca catggatggg catttcttct tcagcaccca ggaccctttc
     2221 acctttgagt gacctcacct ctccctctta tgtagacaca cgtgcacaca cacagacata
     2281 tatgcagttt ggtctcatgc tttttctttt tctttctttc tttttttaaa tcacaccagg
     2341 ctttataatg ttctgttcct acagaccatg cctgcaccct gctttcatcc caagccttac
     2401 aactccatct tccatcctga tgtctttgtc ccaagcagca atctgtcttg gaagcagtgg
     2461 ctgagtttac ttttctgaaa aggtttagag gaaccaggat ggagatgact ttcccttgcg
     2521 ggaatagaat tattcccaca atttatttac tgctagccca agtacacaca cacacacaca
     2581 cacatcactc ccttctgatg ccccaaagcc aactcctgcc accccacacc gaagtcctca
     2641 aacggaaaag aaaatgtatt tgtgccttct gtgagggata ggggacaagg gatcccaggt
     2701 gtccccattt cccgccccct caccttctcc agccccgccc cccacagcaa taagaacttt
     2761 ctctctccct taaactctcc tcttatttgt agtttggaca aatatattta tatgatatgt
     2821 gtaaaaaaaa aaaaaaaaaa
//
