LOCUS       NM_153163               4856 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus Ca2+-dependent activator protein for secretion 2
            (Cadps2), transcript variant 1, mRNA.
ACCESSION   NM_153163
VERSION     NM_153163.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4856)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4856)
  AUTHORS   Guo,Y., Xiang,P., Sun,X., Liu,W., Zhou,J., Yin,B., Hou,L.,
            Qiang,B., Li,H., Shu,P. and Peng,X.
  TITLE     Docking protein 6 (DOK6) selectively docks the neurotrophic
            signaling transduction to restrain peripheral neuropathy
  JOURNAL   Signal Transduct Target Ther 9 (1), 32 (2024)
   PUBMED   38351062
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4856)
  AUTHORS   Cattaneo,P., Hayes,M.G.B., Baumgarten,N., Hecker,D., Peruzzo,S.,
            Aslan,G.S., Kunderfranco,P., Larcher,V., Zhang,L., Contu,R.,
            Fonseca,G., Spinozzi,S., Chen,J., Condorelli,G., Dimmeler,S.,
            Schulz,M.H., Heinz,S., Guimaraes-Camboa,N. and Evans,S.M.
  TITLE     DOT1L regulates chamber-specific transcriptional networks during
            cardiogenesis and mediates postnatal cell cycle withdrawal
  JOURNAL   Nat Commun 13 (1), 7444 (2022)
   PUBMED   36460641
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4856)
  AUTHORS   Fujima,S., Yamaga,R., Minami,H., Mizuno,S., Shinoda,Y.,
            Sadakata,T., Abe,M., Sakimura,K., Sano,Y. and Furuichi,T.
  TITLE     CAPS2 Deficiency Impairs the Release of the Social Peptide
            Oxytocin, as Well as Oxytocin-Associated Social Behavior
  JOURNAL   J Neurosci 41 (20), 4524-4535 (2021)
   PUBMED   33846232
REFERENCE   5  (bases 1 to 4856)
  AUTHORS   Yoo,H., Yang,S.H., Kim,J.Y., Yang,E., Park,H.S., Lee,S.J.,
            Rhyu,I.J., Turecki,G., Lee,H.W. and Kim,H.
  TITLE     Down-regulation of habenular calcium-dependent secretion activator
            2 induces despair-like behavior
  JOURNAL   Sci Rep 11 (1), 3700 (2021)
   PUBMED   33580180
  REMARK    GeneRIF: Down-regulation of habenular calcium-dependent secretion
            activator 2 induces despair-like behavior.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4856)
  AUTHORS   Sadakata,T., Washida,M. and Furuichi,T.
  TITLE     Alternative splicing variations in mouse CAPS2: differential
            expression and functional properties of splicing variants
  JOURNAL   BMC Neurosci 8, 25 (2007)
   PUBMED   17428348
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 4856)
  AUTHORS   Speidel,D., Bruederle,C.E., Enk,C., Voets,T., Varoqueaux,F.,
            Reim,K., Becherer,U., Fornai,F., Ruggieri,S., Holighaus,Y.,
            Weihe,E., Bruns,D., Brose,N. and Rettig,J.
  TITLE     CAPS1 regulates catecholamine loading of large dense-core vesicles
  JOURNAL   Neuron 46 (1), 75-88 (2005)
   PUBMED   15820695
REFERENCE   8  (bases 1 to 4856)
  AUTHORS   Sadakata,T., Mizoguchi,A., Sato,Y., Katoh-Semba,R., Fukuda,M.,
            Mikoshiba,K. and Furuichi,T.
  TITLE     The secretory granule-associated protein CAPS2 regulates
            neurotrophin release and cell survival
  JOURNAL   J Neurosci 24 (1), 43-52 (2004)
   PUBMED   14715936
  REMARK    GeneRIF: results suggest that CAPS2 mediates the
            depolarization-dependent release of NT-3 and BDNF from granule
            cells, leading to regulation in cell differentiation and survival
            during cerebellar development
REFERENCE   9  (bases 1 to 4856)
  AUTHORS   Speidel,D., Varoqueaux,F., Enk,C., Nojiri,M., Grishanin,R.N.,
            Martin,T.F., Hofmann,K., Brose,N. and Reim,K.
  TITLE     A family of Ca2+-dependent activator proteins for secretion:
            comparative analysis of structure, expression, localization, and
            function
  JOURNAL   J Biol Chem 278 (52), 52802-52809 (2003)
   PUBMED   14530279
  REMARK    GeneRIF: identification, cloning, and comparative characterization
            of a second mammalian CAPS isoform, CAPS2; concluded that at the
            functional level, CAPS2 is largely redundant with CAPS1
REFERENCE   10 (bases 1 to 4856)
  AUTHORS   Cisternas,F.A., Vincent,J.B., Scherer,S.W. and Ray,P.N.
  TITLE     Cloning and characterization of human CADPS and CADPS2, new members
            of the Ca2+-dependent activator for secretion protein family
  JOURNAL   Genomics 81 (3), 279-291 (2003)
   PUBMED   12659812
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153831.4, AC155850.6, AC153636.2, AC167725.9 and AC153639.4.
            
            On Apr 1, 2022 this sequence version replaced NM_153163.4.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1, also known as
            CAPS2b).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB291947.1, AK038568.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-512               AC153831.4         14184-14695
            513-626             AC155850.6         104424-104537
            627-959             AC153636.2         19376-19708
            960-1040            AC153636.2         46691-46771
            1041-1277           AC153636.2         58588-58824
            1278-1399           AC153636.2         62738-62859
            1400-1511           AC167725.9         9549-9660
            1512-1651           AC167725.9         40815-40954
            1652-1718           AC167725.9         93674-93740
            1719-1827           AC167725.9         108494-108602
            1828-2028           AC167725.9         110348-110548
            2029-2165           AC167725.9         124628-124764
            2166-2353           AC167725.9         126783-126970
            2354-2455           AC167725.9         147226-147327
            2456-2519           AC167725.9         152182-152245
            2520-2643           AC167725.9         154708-154831
            2644-2664           AC167725.9         156635-156655
            2665-2768           AC167725.9         181785-181888
            2769-2777           AC167725.9         183510-183518
            2778-2934           AC167725.9         193349-193505
            2935-3076           AC153639.4         181852-181993       c
            3077-3196           AC153639.4         181615-181734       c
            3197-3352           AC153639.4         176112-176267       c
            3353-3500           AC153639.4         174538-174685       c
            3501-3575           AC153639.4         166965-167039       c
            3576-3659           AC153639.4         155263-155346       c
            3660-3692           AC153639.4         155126-155158       c
            3693-3800           AC153639.4         140496-140603       c
            3801-3905           AC153639.4         122078-122182       c
            3906-4856           AC153639.4         115598-116548       c
FEATURES             Location/Qualifiers
     source          1..4856
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 10.57 cM"
     gene            1..4856
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /note="Ca2+-dependent activator protein for secretion 2"
                     /db_xref="GeneID:320405"
                     /db_xref="MGI:MGI:2443963"
     exon            1..512
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            513..626
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            627..959
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1040
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1041..1277
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1399
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..1511
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1512..1651
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..1718
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1719..1827
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1828..2028
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            2029..2165
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            2166..2353
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            2354..2455
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            2456..2519
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            2520..2643
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            2644..2664
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            2665..2768
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            2769..2777
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            2778..2934
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            2935..3076
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            3077..3196
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            3197..3352
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            3353..3500
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            3501..3575
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            3576..3659
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            3660..3692
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            3693..3800
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            3801..3905
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     exon            3906..4856
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4762..4767
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /note="hexamer: AATAAA"
     polyA_site      4783
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /note="major polyA site"
     regulatory      4814..4819
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /note="hexamer: ATTAAA"
     regulatory      4823..4828
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
                     /note="hexamer: AGTAAA"
     polyA_site      4833
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
     polyA_site      4856
                     /gene="Cadps2"
                     /gene_synonym="A230044C21Rik; Caps-2; Caps2; Cpd2"
ORIGIN      
        1 actcgggcgc cgaactcgac gtgtccggaa agcccgggcc actttccctt tcgttctgcg
       61 gccgcggcgc accgacctag gttcccgcgg acccgcgggg acagctgcgc tcggcgagaa
      121 gccccaggga tcgcgggcca agcccaggcg tcccagccag caccatgctc gacccgtctt
      181 ccagcgagga ggagtcggac gaggggctgg aggaggagag ccgcgaggtg ttggtggcgc
      241 cgggcgtctc ccagcgagcg ccgccggccg cggctcggga agggcggcgg gacgcgccgg
      301 gacgctccgg tggtggcagc ggcggcggag cggccagacc cgtgagcccg agcccctcgg
      361 tactcagcga ggggcgaaat gagcccgagc tgcagctgga cgaggagcag gagcggcgca
      421 tccgcctgca gctctacgtc ttcgtggtga ggtgcatcgc gtacccattc aacgccaagc
      481 agcccaccga catggcccgg aggcagcaga agcttaacaa acaacaattg cagttactga
      541 aagaacggtt ccaggccttt ctcaatggag aaactcagat agtagcagac gaagccttct
      601 gcaatgccgt ccggagttac tatgaggtgt ttctaaagag tgaccgtgtg gccagaatgg
      661 ttcaaagtgg aggatgctct gctaatgatt tcagagaggt gtttaagaag aacatagaaa
      721 aacgtgtccg tagcctgcca gagatagatg gcctgagcaa agagacagtg ctgagctcat
      781 ggatagccaa atatgacgcc atttacaggg gagaagaaga tttgtgcaaa cagccgaaca
      841 ggatgaccct cagtgccgtg tctgagctta ttctgagtaa ggagcagctc tatgaaatgt
      901 tccagcagat tctgggcatt aagaagctgg aacaccagct actttataac gcatgccagc
      961 tggataacgc tgatgaacaa gcagcccaga tcagaaggga acttgatggc cgcctgcagt
     1021 tggcagagaa gatggcaaag gagagaagat tccccagatt catctcgaaa gaaatggaga
     1081 gtatgtacat tgaagagctg cgagcctccg tgaacctgct aatggccaat ttagaaagtc
     1141 ttccagtttc aaaaggtggc ccggaattta aattacaaaa attaaagcgt tcgcagaact
     1201 ctgcgtttct ggacctggga gatgagaacg agatccagct gtccaagtcg gatgtggtgt
     1261 tgtcgttcac gttagagatt gtcatcatgg aagtgcaagg actgaaatct gtggctccca
     1321 atcgaatcgt ttactgcaca atggaggtgg aaggaggaga aaaactccag acagaccagg
     1381 ctgaagcatc aaggccacaa tgggggaccc aaggagattt caacactacc caccctcggc
     1441 ctgtcgtcaa agtgaagctc ttcacagaaa gcacgggggt cctggccctg gaagacaagg
     1501 aactgggcag ggtggtgtta tacccaactt ctaatagctc caagtcagca gagttacacc
     1561 gaatgacagt acccaagaac agtcaggact cggacctaaa gatcaaattg gcagtgcgca
     1621 tggataaacc agcacacatg aagcatagtg ggtacctgta tgcccttgga cagaaggttt
     1681 ggaaaagatg gaaaaagcgt tactttgttc tcgttcaggt tagccagtac acctttgcta
     1741 tgtgcagcta tagagaaaaa aagtcggaac cacaggaatt aatgcaactg gaaggataca
     1801 cagtggatta cacagaccct cacccaggcc ttcagggtgg tcaggtgttc ttcaacgctg
     1861 ttaaagaggg agatactgtg atctttgcca gtgatgatga acaggacaga atattatggg
     1921 tacaagccat gtacagggct acaggccagt cttacaaacc agttcctgca gtccaaagcc
     1981 agaagctgaa tcctaaaggc ggagctctcc atgcagatgc tcagctttat gcagaccgtt
     2041 ttcagaaaca cgggatggat gagtttattt ctgcgagtcc ttgcaagctt gaccatgcct
     2101 tcctcttcag aattctccag agacagactt tggatcacag actgaatgat tcgtattctt
     2161 gtttggggtg gtttagccct ggccaagtct ttgtgttaga tgagtactgt gcccgctacg
     2221 gagtgagagg ctgtcacagg catctctgct accttacaga actgatggaa cattcagaaa
     2281 acggtgctgt cattgacccc accctgctcc attacagctt tgcattctgt gcctctcacg
     2341 tgcacggcaa caggcctgat gggattggaa cggtttcagt ggaagagaaa gaaagatttg
     2401 aggagataaa agaccgactt tcttcgcttt tagaaaacca gatcagccac ttcagatact
     2461 gctttccctt cggacgacct gagggtgccc taaaagctac gctctcctta cttgaaaggg
     2521 ttttaatgaa agacattgcc actcctatcc ctgcggagga ggtgaagaaa gtggtcagaa
     2581 aatgtctgga gaaagctgcc ttgatcaatt acactaggct cacagaatat gccaaaatag
     2641 aagggcccgc agaaaaggaa acagagacca tgaaccaggc aactcctgcc aggaagctgg
     2701 aagaggttct tcatcttgca gagctctgca tagaagtcct acagcaaaat gaggagcatc
     2761 atgctgaggg aagagaggca tttgcctggt ggcctgactt gttggccgag catgcagaga
     2821 agttttgggc tttattcaca gtagacatgg atactgcgct ggaggcccaa cctcaagact
     2881 cctgggatag ctttcccctt ttccagctgc ttaataattt cctcagaaat gacacacttt
     2941 tgtgtaatgg aaaattccac aagcacttgc aagaaatctt tgtgcccttg gttgtccgct
     3001 acgttgacct gatggagtct gccatcgccc agtccattca cagaggtttt gagcaggaga
     3061 catggcagcc tgtcaagaat atcgccaaca gtcttcccaa tgtagctctt ccaaaagttc
     3121 caagtctgcc tcttaatctt ccacagattc ctagcttttc tactcctccg tggatggctt
     3181 ctttatatga gtccaccaat ggctcaacaa cttccgagga tctgttctgg aagctcgatg
     3241 cgctgcaaat gttcgtcttt gatctccatt ggccagaaca agagtttgcc caccacttag
     3301 agcaaagact taaactaatg gccagtgata tgatagaggc gtgtgtcaaa agaacaagaa
     3361 ctgcgttcga actcaagcta caaaaggcaa acaaaacaac tgacttgcgc atcccagctt
     3421 ccgtgtgcac aatgtttaat gtattagttg atgctaaaaa gcaaagcacc aagctgtgtg
     3481 ccctggatgg aggacaagag caacagtacc attcaaaaat agatgatttg attgacaaca
     3541 ccgtgaaaga aatcattgca ctgctggttt caaagtttgt ttcagtgttg gaaggggtgc
     3601 tttcgaagtt gtcgaggtat gacgaaggca ctttcttctc atccatcctg tccttcactg
     3661 tgaaagcagc tgcaaaatat gtggatgtcc ctaaaccagg aatggatctg gcagacacct
     3721 acattatgtt tgtccggcaa aaccaggata ttcttcgaga aaaagtcaat gaagagatgt
     3781 acatagaaaa gttgtttgat caatggtaca gcaattccat gaaagtcatt tgtgtgtggc
     3841 tggctgacag actagacctc cagcttcata tttaccaact gaagacgctc atcaagattg
     3901 tgaagaaaac ctatagggat ttccgattgc agggtgtgtt ggaggggacg ctgaacagta
     3961 agacatatga tactctgcac agacgtctaa ctgtagagga ggccacagcc tctgtctcag
     4021 aaggcggagg acttcagggc attaccatga aggacagtga tgaggaggaa gaaggctgat
     4081 gatgcacagc tcctcgaaag gaaggaagac cttggcattg ctctgacctt ggcattgctc
     4141 tgtgcacctt gtccttgtaa ctgtttttac tgtcttggcc aaataaaaat gctctaattt
     4201 ctttagaatg tgaacttgga gataaagaga gaaatgccat gtatttttgg aaagaaaacc
     4261 atattcacat gtatagcttg acctaaaaat tggctgtgct cgtgactgga atatgaactg
     4321 cttttgtggt tttgttttgt tttgtttgtt tgttgttaat atatttgact tttcttttta
     4381 atagtaatct caaaataatg tcctatgtgt catatgaggt atgcatctcc catgacacag
     4441 cattgtgaag agaagccatt tctggtcaca gcaccaatcc tattgttact tctgtcaaag
     4501 tggtgtgcct cccacttata atttatgtat gaagtttgtt ctgtaatttg ccagtgttgt
     4561 gatgtgtaga aaactttagc cttggttttc ataactctga atttgtctgc aggtgtaatt
     4621 ctggacttca aagagtttca tacccaaatg tagactagat tatccacagg cttacatcct
     4681 gtttctttct gaacattttc tttcatgtgt accatgtcgc caggtgtgct tccaacacaa
     4741 gtgtaacagc ttgccggcaa taataaaaat ccattcagtc agagcaacct ctatgttcat
     4801 tacacttaag tagattaaat gcagtaaaaa atatttgcag tatctcaaac atccca
//
