LOCUS       NM_178721               9580 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus cell adhesion molecule 2 (Cadm2), transcript variant
            1, mRNA.
ACCESSION   NM_178721 XM_489588
VERSION     NM_178721.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9580)
  AUTHORS   Sanchez-Roige,S., Jennings,M.V., Thorpe,H.H.A., Mallari,J.E., van
            der Werf,L.C., Bianchi,S.B., Huang,Y., Lee,C., Mallard,T.T.,
            Barnes,S.A., Wu,J.Y., Barkley-Levenson,A.M., Boussaty,E.C.,
            Snethlage,C.E., Schafer,D., Babic,Z., Winters,B.D., Watters,K.E.,
            Biederer,T., Mackillop,J., Stephens,D.N., Elson,S.L.,
            Fontanillas,P., Khokhar,J.Y., Young,J.W. and Palmer,A.A.
  CONSRTM   23andMe Research Team
  TITLE     CADM2 is implicated in impulsive personality and numerous other
            traits by genome- and phenome-wide association studies in humans
            and mice
  JOURNAL   Transl Psychiatry 13 (1), 167 (2023)
   PUBMED   37173343
  REMARK    GeneRIF: CADM2 is implicated in impulsive personality and numerous
            other traits by genome- and phenome-wide association studies in
            humans and mice.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9580)
  AUTHORS   Nozawa,O., Miyata,M., Shiotani,H., Kameyama,T., Komaki,R.,
            Shimizu,T., Kuriu,T., Kashiwagi,Y., Sato,Y., Koebisu,M., Aiba,A.,
            Okabe,S., Mizutani,K. and Takai,Y.
  TITLE     Necl2/3-mediated mechanism for tripartite synapse formation
  JOURNAL   Development 150 (4) (2023)
   PUBMED   36458527
REFERENCE   3  (bases 1 to 9580)
  AUTHORS   Ehrman,J.M., Merchan-Sala,P., Ehrman,L.A., Chen,B., Lim,H.W.,
            Waclaw,R.R. and Campbell,K.
  TITLE     Formation of the Mouse Internal Capsule and Cerebral Peduncle: A
            Pioneering Role for Striatonigral Axons as Revealed in Isl1
            Conditional Mutants
  JOURNAL   J Neurosci 42 (16), 3344-3364 (2022)
   PUBMED   35273083
REFERENCE   4  (bases 1 to 9580)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 9580)
  AUTHORS   Sukhanov,N., Vainshtein,A., Eshed-Eisenbach,Y. and Peles,E.
  TITLE     Differential Contribution of Cadm1-Cadm3 Cell Adhesion Molecules to
            Peripheral Myelinated Axons
  JOURNAL   J Neurosci 41 (7), 1393-1400 (2021)
   PUBMED   33397712
REFERENCE   6  (bases 1 to 9580)
  AUTHORS   Golan,N., Kartvelishvily,E., Spiegel,I., Salomon,D., Sabanay,H.,
            Rechav,K., Vainshtein,A., Frechter,S., Maik-Rachline,G.,
            Eshed-Eisenbach,Y., Momoi,T. and Peles,E.
  TITLE     Genetic deletion of Cadm4 results in myelin abnormalities
            resembling Charcot-Marie-Tooth neuropathy
  JOURNAL   J Neurosci 33 (27), 10950-10961 (2013)
   PUBMED   23825401
REFERENCE   7  (bases 1 to 9580)
  AUTHORS   Thomas,L.A., Akins,M.R. and Biederer,T.
  TITLE     Expression and adhesion profiles of SynCAM molecules indicate
            distinct neuronal functions
  JOURNAL   J Comp Neurol 510 (1), 47-67 (2008)
   PUBMED   18615557
REFERENCE   8  (bases 1 to 9580)
  AUTHORS   Yoshida,Y., Han,B., Mendelsohn,M. and Jessell,T.M.
  TITLE     PlexinA1 signaling directs the segregation of proprioceptive
            sensory axons in the developing spinal cord
  JOURNAL   Neuron 52 (5), 775-788 (2006)
   PUBMED   17145500
REFERENCE   9  (bases 1 to 9580)
  AUTHORS   Biederer,T.
  TITLE     Bioinformatic characterization of the SynCAM family of
            immunoglobulin-like domain-containing adhesion molecules
  JOURNAL   Genomics 87 (1), 139-150 (2006)
   PUBMED   16311015
REFERENCE   10 (bases 1 to 9580)
  AUTHORS   Shingai,T., Ikeda,W., Kakunaga,S., Morimoto,K., Takekuni,K.,
            Itoh,S., Satoh,K., Takeuchi,M., Imai,T., Monden,M. and Takai,Y.
  TITLE     Implications of nectin-like
            molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in cell-cell adhesion
            and transmembrane protein localization in epithelial cells
  JOURNAL   J Biol Chem 278 (37), 35421-35427 (2003)
   PUBMED   12826663
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB667048.1, AK165030.1, AK043760.1, CT010571.7 and BF458515.1.
            
            On Mar 21, 2009 this sequence version replaced NM_178721.3.
            
            Transcript Variant: This variant (1) encodes isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK165030.1, AK038842.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849375,
                                           SAMN00849376 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-589               BB667048.1         9-597
            590-2013            AK165030.1         587-2010
            2014-3897           AK043760.1         1997-3880
            3898-4616           AK165030.1         3895-4613
            4617-9461           CT010571.7         29744-34588
            9462-9580           BF458515.1         1-119               c
FEATURES             Location/Qualifiers
     source          1..9580
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 37.96 cM"
     gene            1..9580
                     /gene="Cadm2"
                     /gene_synonym="2900078E11Rik; 9330131D06; A830029E02Rik;
                     Igdf4d; Igsf4d; NECL3; SynCAM 2; SynCAM2"
                     /note="cell adhesion molecule 2"
                     /db_xref="GeneID:239857"
                     /db_xref="MGI:MGI:2442722"
     exon            1..738
                     /gene="Cadm2"
                     /gene_synonym="2900078E11Rik; 9330131D06; A830029E02Rik;
                     Igdf4d; Igsf4d; NECL3; SynCAM 2; SynCAM2"
                     /inference="alignment:Splign:2.1.0"
     CDS             678..1892
                     /gene="Cadm2"
                     /gene_synonym="2900078E11Rik; 9330131D06; A830029E02Rik;
                     Igdf4d; Igsf4d; NECL3; SynCAM 2; SynCAM2"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; immunoglobulin superfamily, member 4; NECL-3;
                     nectin-like protein 3; immunoglobulin superfamily member
                     4D; synaptic cell adhesion molecule 2"
                     /codon_start=1
                     /product="cell adhesion molecule 2 isoform 1 precursor"
                     /protein_id="NP_848836.2"
                     /db_xref="CCDS:CCDS28270.1"
                     /db_xref="GeneID:239857"
                     /db_xref="MGI:MGI:2442722"
                     /translation="MIWKRSAVLRFYSVCGLLLQAAASKSKVKGSQGQFPLTQNVTVV
                     EGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSISVSD
                     VSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKTSGS
                     KPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHES
                     LNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQALTLTCESKGKPLPEPVLWTKDGAE
                     LPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDPNSLAGQNGP
                     DHALIGGIVAVVVFVTLCSIFLLGRYLARHKGTYLTNEAKGAEDAPDADTAIINAEGS
                     QVNAEEKKEYFI"
     exon            739..765
                     /gene="Cadm2"
                     /gene_synonym="2900078E11Rik; 9330131D06; A830029E02Rik;
                     Igdf4d; Igsf4d; NECL3; SynCAM 2; SynCAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            766..915
                     /gene="Cadm2"
                     /gene_synonym="2900078E11Rik; 9330131D06; A830029E02Rik;
                     Igdf4d; Igsf4d; NECL3; SynCAM 2; SynCAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1068
                     /gene="Cadm2"
                     /gene_synonym="2900078E11Rik; 9330131D06; A830029E02Rik;
                     Igdf4d; Igsf4d; NECL3; SynCAM 2; SynCAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1206
                     /gene="Cadm2"
                     /gene_synonym="2900078E11Rik; 9330131D06; A830029E02Rik;
                     Igdf4d; Igsf4d; NECL3; SynCAM 2; SynCAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1377
                     /gene="Cadm2"
                     /gene_synonym="2900078E11Rik; 9330131D06; A830029E02Rik;
                     Igdf4d; Igsf4d; NECL3; SynCAM 2; SynCAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1378..1468
                     /gene="Cadm2"
                     /gene_synonym="2900078E11Rik; 9330131D06; A830029E02Rik;
                     Igdf4d; Igsf4d; NECL3; SynCAM 2; SynCAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1647
                     /gene="Cadm2"
                     /gene_synonym="2900078E11Rik; 9330131D06; A830029E02Rik;
                     Igdf4d; Igsf4d; NECL3; SynCAM 2; SynCAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1648..1773
                     /gene="Cadm2"
                     /gene_synonym="2900078E11Rik; 9330131D06; A830029E02Rik;
                     Igdf4d; Igsf4d; NECL3; SynCAM 2; SynCAM2"
                     /inference="alignment:Splign:2.1.0"
     exon            1774..9564
                     /gene="Cadm2"
                     /gene_synonym="2900078E11Rik; 9330131D06; A830029E02Rik;
                     Igdf4d; Igsf4d; NECL3; SynCAM 2; SynCAM2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcccttgtgt ctggtgctcg ctagagctgc tgctgccgcc gctgccgccg ccgccgcctc
       61 cgtcgccgcc gccgccgccg ccgccgccgc cgccgccact gctgctgctg cagccggagc
      121 atccgggagc cgccgccgcc gctgctgcca ccgctaccaa gcgctgctac cactgctgcc
      181 cacctcttct cccaggactc tgacacccga gcgcgagcgg cggtgctgcc agcttgctgc
      241 ccctgtcccc cacccctccc ttccgtgacc tacccactcc ttgcagccct cgcctgcacc
      301 ttccccgaca ccccggcatc tccgcatcac ctgcctgagc aacctccggg cgggctctgg
      361 gacttgcctc gagctccgaa aggaaggcaa ggtccaaacc ggtgccgggc agatcggttg
      421 tcggggctgc accaccagca gcagaaggag aagaaactat ttagcccacc gaaaccccat
      481 tctgcgggtg ctctgccact gccgcttttg ctgccggcaa ccagcttccg cgcgggttcg
      541 aacacagcag cggcggtacc gtgggtccgg cgggagccgg ggggacgaca ccagcggagc
      601 ccttgcactg tgtggttcgc tcaaccagca tctccttgcc ccctcgatcc ttccccagac
      661 ccttaaaaga agggaccatg atttggaaac gcagcgcggt tctccgcttc tacagtgtct
      721 gcgggctcct gttacaagcg gctgcttcaa aaagtaaagt caaaggcagc caagggcagt
      781 ttccactaac tcagaatgtc acggttgttg aaggtggaac tgcaattttg acctgcagag
      841 ttgatcaaaa tgataacacc tccctccagt ggtcaaatcc agctcaacag actctgtact
      901 tcgatgacaa gaaagcttta agggacaatc ggatcgagct ggttcgcgct tcttggcatg
      961 agttgagcat cagtgtcagt gatgtgtctc tctcggatga aggacagtac acctgctcct
     1021 tatttacaat gcctgtcaaa acttccaagg cctatctcac tgtcctgggt gttccggaga
     1081 agcctcagat tagtggattt tcgtcacccg tcatggaggg agacctgatg cagctgacgt
     1141 gtaagacgtc cggcagtaag cctgcggctg atataagatg gttcaaaaat gacaaagaaa
     1201 tcaaagatgt gaagtacttg aaagaggagg atgctaaccg aaagaccttc accgttagca
     1261 gcacgctgga tttccgagtg gaccgtagcg atgatggagt ggcggtcatc tgcagagtag
     1321 accatgagtc cctcaatgcc acccctcagg tagccatgca ggtgctagaa attcactata
     1381 caccatcagt taagattata ccatcgactc cttttccaca agaagggcag gctttaacgt
     1441 tgacctgtga atctaaagga aaaccactgc cagaacctgt tttgtggacg aaagatggtg
     1501 ccgaattacc agatcctgat cgaatggttg tgagtggtag ggaactcaac attctcttcc
     1561 tgaacaaaac ggacaatggc acttaccgat gtgaagccac taacaccatt ggccaaagca
     1621 gtgccgagta tgtcctcatt gttcacgatc ccaattctct ggctggccag aatggccctg
     1681 accatgctct catcggagga atagtggctg ttgttgtatt tgttacactg tgctccatat
     1741 tcctgcttgg ccgatatctg gcaagacata aaggaacata tctaacaaat gaagctaaag
     1801 gagccgaaga tgcaccagat gccgacacag ccattatcaa tgctgaaggc agccaagtca
     1861 atgccgaaga gaaaaaagag tatttcattt aaaattcagg cttcaagttc tgagttttac
     1921 ctaccaggct gactgctgga gaaaactggc aatcatcttt cagaaatcat tccaaccatc
     1981 ttcttctact acttttatta acacccatac tgtactgctc tcagtagcca gtgtatacca
     2041 acaatcagca gttgaaagca tcattcttta attactgtac catccataat gcaggacatt
     2101 tcttattgcc taaattttac accattgctc ttttaacata cagtgcttga atatacagcc
     2161 ttaacaatgt taatcatctc actggatcat ggtattgagt tgtttttata cattgaagaa
     2221 atgtatgcag agccccgccc ctacatttgt ttttcttgaa gtcatagact ttattggttt
     2281 gccattggac agttatcaca agtcacagga ttaggtgatg acctaatgtg tttaagctta
     2341 atcgaagatt agtggtttac aaacaatgtt ttctacctgt ctatcttcaa agataacatg
     2401 ttgtggaaac atacgcccta gaaaacacaa actgaaaaaa cattgtagtg tagtttctgg
     2461 aatgtttgag attatactgg taatactgta tcaagtggct attttaaaat ttagtgtttg
     2521 atacaggcgc catgtgtatg gattatactc atgacatgac accttatatt attatataga
     2581 tcctaccatt aggttattgt agcttcattt accaataaat tattacaaac atttaactgc
     2641 tttgggaatc ataaagattt cattcatttc tctatttgat tctataattt atttgttcca
     2701 taaggattca cctgcctaaa caaaactgaa gtagggcaca attttgagac attttagtat
     2761 ctgtatatag tgcatataat aaatccaatt aaacattatt tgatacatat ttaacttttt
     2821 tggctgtagg ttattcagtc ataagtacgc attttctaac gtccattata tccctttaga
     2881 tattacataa actgatatta taagtagata acatggatta gtatttttgt ctgtatgtcc
     2941 cagcactgtc aacaacaaaa tttttctagt tcttgttaat ttttatttgt tatacaatgg
     3001 aagcacaatg ttacaaggaa aggtaatttt aagctaacaa ccagtgcaca gcctcaggtt
     3061 ttaaatcaca accacagttg aataataacc taaaaacaaa ctcttagttt gatttaattt
     3121 aaaaaaacaa ctttacataa tttaatttgg cagtttcagg gctgcttaac tatgttgatt
     3181 tgccaaaaag ggagtgttta tgatattttc tgcataaatg agctaattct ttatattaaa
     3241 ctcctgtcta tgcattctgt gaggtacaaa cttatgaaac agagagtgat agagaacccg
     3301 tgccgtgctc ttaactccaa ggtgaaagtc tctttctctg gattacttta aattttggta
     3361 tattgaaata ttataaaatt ctgtaatctt aaatatgtca caaagccaat acaaatcttc
     3421 tatctatggg tgaaataaaa tattggtaga atagttttca ttacacttat tggaagctaa
     3481 agaataaaga tccagttaga tgaaaaaatt attttcccat ttgcaagcat tgcaccatta
     3541 agaagaaaac aaaaattaca atatggtagc tgtacttgtg atgactaaca gcatggcgga
     3601 attttaaaaa taccttggaa cttatttgcg gggaagaagg atgattgaat acaacatcct
     3661 atgctaataa caacacgagg acaagggtgc tgtatattag attatttatc agaaaagtat
     3721 caaacattta aggacaatgt tagaatttta attttttttt aaattgtgta gcatttatct
     3781 tgttgatttc ttacaaaaga aaaaggacga tgtcagtcaa gcagcacttt tttcaagata
     3841 tacagaacat aaataatatg atgtggttga gtgttaacat aataaatcat atacagtatg
     3901 acattttaag gaaataagtc tgcattgatg tgattgcatg cttgttttta cagttcactc
     3961 cataccatct gtggaaaaaa atgcaataat atgttaatat agtatggtag ttcgagagaa
     4021 tcaggtaggt gcctctagac acattgaaac tagaataggt ctataaactg ctcatatctt
     4081 tcaatgcata atctttagaa agactccaca cagcaaaaat tcatcctgtt agtacaaaac
     4141 ggaaaggttc ttattgctaa gtatgttgta taactgtatc atcagttact atttaaagcc
     4201 taatttcagg atacatttac aaaattgcta ctcttcatcg atgttgtatt tataaccttc
     4261 atctatattc tacttggctc caactgctaa aattgttgcc taaataacag aaacattatt
     4321 tataacacta taaaattaga aaccccaaat tgtttgcatt tcaagacttt tgactctttt
     4381 gacccttctg agaaatacac caacccatta gaacttgtaa aataaaatca ctggcagata
     4441 aaaaattagt gggctctaat caaatgattt tcagtcaaac gtagctaatt ttgattgaat
     4501 aacatttcct gacatggaac aaaagtgatg gagttatact ttcctgtatt gaaagcttat
     4561 ttgattttca atgaaggaat caagttacga gaattgtagg cattccccat tccagcaaat
     4621 aaaaaataaa taaataaatg aaatcagatt tctaaattgg actcatgtca acggaaaaac
     4681 ctgaaatatg cccagtcata tgcacatgga gctgatctct gtctctgcca aaagagttca
     4741 gtagatagga aacacagtga aaagggtgtg tgtgtacact cctcaaaggc caagagcatc
     4801 attcactaca aaaggaagtt cctctctgcc agaaatgttt acagtgtaca ttgattgtcc
     4861 tccatcagta agatctaacc agaattattc ttgtcttctt ttcctttttg aatgtcctgg
     4921 gaagaatggt gggaccaaaa ctataaggaa aaaaaaaaaa aaggaaaagt atatgagtaa
     4981 aatagtaaag acacaaaacc ccattggaat attggtgtgt gtgtgtgtgt gtgtgtgtgt
     5041 gtgtgtgtgt gtgtgtgtgt gtggtgtgtg agtgagtgtg tgtgtttgca tgtgcatgtc
     5101 tgtgtgtgtg tgtgagagag agagagtgtg tgtgtggtgt gtgtgagtgt gtgtgtgttt
     5161 gcatgtgcat gtctgtgcgc gcgcgcgtgt gtgtgtgtgt attgaagaga agagaaatta
     5221 aaccaaacac agaaaaagag attccaattc gttttctttt accagaaatt gcaagaagca
     5281 atttatgaaa cctgatattg ggatttaatc tagaaaccgg atgatctcat tagagatgtt
     5341 tagtctttca caaaaacttt acaattacag taacaaatag agaaagaaaa acaactttcc
     5401 tgattatggc aaagaagcta acacctcatt tgtttggttt gggtttttgt ttggtttttg
     5461 taagtatata aatattcaat taaagagaca ggctcacttg taattatgaa ctcatgactg
     5521 tgacagcatt gagataccat ataggcacat gtacagcaga tgtttgacag taacggttct
     5581 tccatgtaac atagcagtta ttgtgtgatt tagtgccact tattgcaaag tgttacccat
     5641 gggcacactg aaaatgcatt tttctccacc ctttgacata cgtataattt aaaagaaaaa
     5701 atataaaatt tcacaccttt ttttttccaa tttgtgatac ttcatatcag actgtagcct
     5761 tcccataata tttttgtccc agaaaacttt tgaaaatgcc cacctttatt tcctttgaca
     5821 catggtaatc tataatgggt acagacaatg aggtgatcaa ctggaatacc tgaaaaacct
     5881 aaaggacgag taatgctttt agttaagtgg caccaagtac acactagaaa ctatgcaaac
     5941 tgtaggtaac tacactgtat gtacacgtaa gtatcttgta ctagctgtgt atggatgttg
     6001 gacacccatg taattataat atgcattttg aattctggga aagaggaaat cttagtgtag
     6061 ataatataat ttgttttgaa atatacattg gcaatattga aatatactca gtgcaatatc
     6121 tctaattcta ttgctggata tttaatgcaa agggttttac aaatcctctt aaagaagatc
     6181 caagagtttt gctaattcat ctctcatgtt ttaaagtact aactacagca agtggtagtt
     6241 tttattctta cttattaagg taacaaagga catttatttg gtttggtttt tactctagag
     6301 aaggaaaaga catggatttt aatctttgat ttcatatcta atcaaattta acattcttaa
     6361 tttttttgaa atgtatgtgc tttagtaaat tgacatactt tatgagtaaa aatttattca
     6421 aagaatgtaa gatatattta gtatttaaag tcacttatat tttaatgagg aaattttctt
     6481 ttctatattt gcctttgttt tcatagcaca acccaaacat gccctttgca cttctatata
     6541 cccttccaaa ggcagtggat tgaacgtagc aggataatca tgagacttga aggggatggt
     6601 atatgtgaat gggttctaaa ataatcagca tatttatgta ttgagattac tctcaaatgc
     6661 aatagttatt ggatatagct ggtaatttct ctgccatgca tacttacaat aattcttcta
     6721 cctctcactt ttaacatggg ctatgatact tcaatataaa tagcagaagt aaatatttac
     6781 aagatatccc aggaagcatc attttgggac cttcataaca atgcactccc cactccctgg
     6841 gaaatctcaa aagccaactt cttgtagtgt attttatggt gtatgggtaa gcgtttgttt
     6901 agcttcgctc tcattagctg catatatagg taacacatga aactttggtg aggacaggtc
     6961 tttccatgcc tagttagtgt tttgctgtta tgtaattgta acttttaaaa agtaatttga
     7021 tggcagcagt ttgcaatcca atttgatatt tcagtttatt tttaaagtat aagaatttct
     7081 tcaaattcaa tgctgtattt taagtacaag tcatgtatat gatttaattt ccagagaaat
     7141 attatctata taaacaaaaa ttaagtattt taaaactgtc tccttatgaa caaataaccc
     7201 caataattca aaatattgcc tcaaaagccc actttttctg cctaggcatg ataggaagtt
     7261 ttcaatgatg taatttaaat atgttaaaat aaaatgccac tttatgagcg tattttccct
     7321 tcaggaaaaa aatagattac ataaatttat taaatattga tggtgaatct ataaaatacg
     7381 cttaaaatta aagtaagagt ttatgttatg tggttatgtt atacatatta tttgatttag
     7441 tctttaacat cgtgtccata tatgtatatg tagtatttat atatggtcat atatatatat
     7501 atatattaca tatatgaaat gtgtgattat tttggagaaa atgggcccaa atgtgaaaaa
     7561 gatgtaaaga aaacattata accccttgga aatatgatgt atatttcaaa gatgttaagt
     7621 ttaaagagaa gtgacaattg cagaggcaca agaaaaaatc taccagggct cagcactcaa
     7681 gcactttccc cacatccagg gtcaaagcag tagcgattcc tacacggact tttaagcgca
     7741 gcatgaaatg cagcattaca cgaacacaca gtactgtcaa acctcaaatg ctttctttct
     7801 ttagatgctt tcccttgtac atgatcctcg tagacatgtt tttatattcg ctgatagtga
     7861 aagtcacgcg caataaaatg taacggttgg aagcagtagt cacgaatcgg ttaaagacaa
     7921 gtacaaaatg ttaacagttg ttatctttct cctcctcgct tttctccgtg gttccgatgt
     7981 gttgactgaa tgtcataaat agaacaaaaa aaagaaaaaa aaagcagaag cttttcaaag
     8041 ctagtaatat tgctccttat aaatatgtaa catttttatc tttatacaaa cttacttcgc
     8101 tgtactcgct gtacctgttg tcgattgatt caatgatgca attgagtagt gatctaaaga
     8161 cttctgagtt tggaatggct gatctcttct tcgtattcag ttcacatcaa catttgcgaa
     8221 tcagttgttt agctttttat tcaaccgtac acattcctta aagacagctc cattcttatc
     8281 ataaacattt cagtgtaaac aaccttggaa caagtttgcc atgttcaaaa aaaaaaaaaa
     8341 aatttaaaga cttatctctg aaaacagtgt ccagaaatgc aggtgttccc ggtaatgaag
     8401 cttcaaaaat aaagtggtct atttatatga catgaaatcc atatcttttg gaagggtata
     8461 cttaatgaca gcactcaaat atattctgtg ctgcaaagaa gatccaaatg aagcatatcg
     8521 cacagaaaac aaacacaatt attaaatcta cttgtatcat gaacattttc acaaaacaaa
     8581 atgcatattg taatattaag tacatgacac ttgcatgtta atatgcctat atactgacaa
     8641 agtattcaat gtgtactgag tggcgcttca aatatgtcat gtacaacact tagaaacatg
     8701 cctacaaagg ttcccacttg catttcatcc tttcagtaaa gtctcctcac acgtgcaaaa
     8761 aaattgtttg ataaatatga aaaaaaataa aatttgaatt ttagttatct gttggacatt
     8821 actgaacttc ttcttcattt agtgtatttt aggttctgaa cacagacatt gagaataaac
     8881 gttcttttct ccagtgaaag attacaaacg atgtggtgga gcatgttctg ttatgccaaa
     8941 cgcattattt tgaatacctt ttttcaattg cattttatat ccatctattt taggtttcct
     9001 caatgacata caattttctt gtaaatttct aaagggaact taaaaaaatg agagctacta
     9061 aatgttatct ttctgataaa acatttaatc attactcctt gaaatgtatg aaccttgtga
     9121 tatgctaagg gttaaaaaat aagtgtcgct gacataaaga attttgcttg agattgccaa
     9181 cattcaaaat tctgtaaaag tacttttaca tccacttatt tgtgtttact aatgttgact
     9241 aggaacagaa gcaaaaatat ctaaaacaaa cttttttatt tctacactct aaccgatata
     9301 tttcaactac ctaagataat gcgattaacc atatatacat cccgagctta taacaataag
     9361 aatttgagat aagcttttaa atttatggaa gattttcttt gtgtctttgg aagttcactt
     9421 accataaggt attttgtagt gtactttaag taacagattt tgttatacag ggtaagccaa
     9481 aggctgtaca agaattagtg ccattgggtc tgatatttgt gttggaccat gaaatattcc
     9541 attaaaattt gtctgtaaat acaaaaaaaa aaaaaaaaaa
//
