LOCUS       NM_019430               1540 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus calcium channel, voltage-dependent, gamma subunit 3
            (Cacng3), mRNA.
ACCESSION   NM_019430 XM_486000
VERSION     NM_019430.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1540)
  AUTHORS   Yamasaki,M., Fukaya,M., Yamazaki,M., Azechi,H., Natsume,R., Abe,M.,
            Sakimura,K. and Watanabe,M.
  TITLE     TARP gamma-2 and gamma-8 Differentially Control AMPAR Density
            Across Schaffer Collateral/Commissural Synapses in the Hippocampal
            CA1 Area
  JOURNAL   J Neurosci 36 (15), 4296-4312 (2016)
   PUBMED   27076426
REFERENCE   2  (bases 1 to 1540)
  AUTHORS   Templin,J.S., Bang,S.J., Soiza-Reilly,M., Berde,C.B. and
            Commons,K.G.
  TITLE     Patterned expression of ion channel genes in mouse dorsal raphe
            nucleus determined with the Allen Mouse Brain Atlas
  JOURNAL   Brain Res 1457, 1-12 (2012)
   PUBMED   22534482
  REMARK    GeneRIF: This study demonistrated that Cacng3 gene expression in
            mouse dorsal raphe nucleus
REFERENCE   3  (bases 1 to 1540)
  AUTHORS   Schwenk,J., Harmel,N., Brechet,A., Zolles,G., Berkefeld,H.,
            Muller,C.S., Bildl,W., Baehrens,D., Huber,B., Kulik,A., Klocker,N.,
            Schulte,U. and Fakler,B.
  TITLE     High-resolution proteomics unravel architecture and molecular
            diversity of native AMPA receptor complexes
  JOURNAL   Neuron 74 (4), 621-633 (2012)
   PUBMED   22632720
REFERENCE   4  (bases 1 to 1540)
  AUTHORS   Menuz,K., Kerchner,G.A., O'Brien,J.L. and Nicoll,R.A.
  TITLE     Critical role for TARPs in early development despite broad
            functional redundancy
  JOURNAL   Neuropharmacology 56 (1), 22-29 (2009)
   PUBMED   18634809
REFERENCE   5  (bases 1 to 1540)
  AUTHORS   Menuz,K., O'Brien,J.L., Karmizadegan,S., Bredt,D.S. and Nicoll,R.A.
  TITLE     TARP redundancy is critical for maintaining AMPA receptor function
  JOURNAL   J Neurosci 28 (35), 8740-8746 (2008)
   PUBMED   18753375
REFERENCE   6  (bases 1 to 1540)
  AUTHORS   Matsuda,S., Miura,E., Matsuda,K., Kakegawa,W., Kohda,K.,
            Watanabe,M. and Yuzaki,M.
  TITLE     Accumulation of AMPA receptors in autophagosomes in neuronal axons
            lacking adaptor protein AP-4
  JOURNAL   Neuron 57 (5), 730-745 (2008)
   PUBMED   18341993
REFERENCE   7  (bases 1 to 1540)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   8  (bases 1 to 1540)
  AUTHORS   Letts,V.A., Mahaffey,C.L., Beyer,B. and Frankel,W.N.
  TITLE     A targeted mutation in Cacng4 exacerbates spike-wave seizures in
            stargazer (Cacng2) mice
  JOURNAL   Proc Natl Acad Sci U S A 102 (6), 2123-2128 (2005)
   PUBMED   15677329
REFERENCE   9  (bases 1 to 1540)
  AUTHORS   Klugbauer,N., Dai,S., Specht,V., Lacinova,L., Marais,E., Bohn,G.
            and Hofmann,F.
  TITLE     A family of gamma-like calcium channel subunits
  JOURNAL   FEBS Lett 470 (2), 189-197 (2000)
   PUBMED   10734232
REFERENCE   10 (bases 1 to 1540)
  AUTHORS   Burgess,D.L., Davis,C.F., Gefrides,L.A. and Noebels,J.L.
  TITLE     Identification of three novel Ca(2+) channel gamma subunit genes
            reveals molecular diversification by tandem and chromosome
            duplication
  JOURNAL   Genome Res 9 (12), 1204-1213 (1999)
   PUBMED   10613843
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC145971.1, AC132248.3 and AW124106.1.
            
            On May 1, 2009 this sequence version replaced NM_019430.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC145971.1, SRR7652917.1153125.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849388, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1029              BC145971.1         1-1029
            1030-1236           AC132248.3         94527-94733         c
            1237-1540           AW124106.1         1-304               c
FEATURES             Location/Qualifiers
     source          1..1540
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 66.81 cM"
     gene            1..1540
                     /gene="Cacng3"
                     /note="calcium channel, voltage-dependent, gamma subunit
                     3"
                     /db_xref="GeneID:54376"
                     /db_xref="MGI:MGI:1859165"
     exon            1..241
                     /gene="Cacng3"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..978
                     /gene="Cacng3"
                     /note="neuronal voltage-gated calcium channel gamma-3
                     subunit; TARP gamma-3; transmembrane AMPAR regulatory
                     protein gamma-3"
                     /codon_start=1
                     /product="voltage-dependent calcium channel gamma-3
                     subunit"
                     /protein_id="NP_062303.2"
                     /db_xref="CCDS:CCDS21816.1"
                     /db_xref="GeneID:54376"
                     /db_xref="MGI:MGI:1859165"
                     /translation="MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKS
                     TSDNETSRKNEEVMTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVR
                     ASSVFPILSVTLLFFGGLCVAASEFHRSRHSVILSAGIFFVSAGLSNIIGIIVYISAN
                     AGDPGQRDSKKSYSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQLRARSHSELLKK
                     STFARLPPYRYRFRRRSSSRSTEPRSRDLSPISKGFHTIPSTDISMFTLSRDPSKLTM
                     GTLLNSDRDHAFLQFHNSTPKEFKESLHNNPANRRTTPV"
     exon            242..325
                     /gene="Cacng3"
                     /inference="alignment:Splign:2.1.0"
     exon            326..466
                     /gene="Cacng3"
                     /inference="alignment:Splign:2.1.0"
     exon            467..1525
                     /gene="Cacng3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1500..1505
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cacng3"
                     /note="hexamer: ATTAAA"
     polyA_site      1525
                     /gene="Cacng3"
                     /note="major polyA site"
ORIGIN      
        1 ccccagccgt tcagagtacc atgaagaatt atgaggatgt gtgacagagg tatccagatg
       61 ttgatcacta ctgtaggagc cttcgcagct tttagtttaa tgaccattgc agtgggcacg
      121 gactactggc tatattccag aggtgtgtgc aggactaaat ctacaagtga caatgaaacc
      181 agcaggaaga atgaagaagt aatgacccac tccgggttgt ggaggacctg ctgcttggaa
      241 ggagctttcc gaggcgtgtg caagaaaatc gatcacttcc cagaagatgc agactatgaa
      301 caggatacag cagaatatct tctacgagct gtgagggcct ccagcgtctt tcccatcctc
      361 agcgtcactc tgctgttttt cgggggactc tgcgtggctg ccagcgagtt ccaccgcagc
      421 aggcacagtg tgatcctcag cgctggcatc ttcttcgtct ctgcagggct aagcaacatc
      481 atcggcatca tagtttatat ctcagccaat gctggagacc ctgggcagag ggactctaaa
      541 aagagctact cctacggctg gtccttttat tttggagcct tctctttcat catcgcggaa
      601 attgtgggcg tggtcgccgt gcacatctat atcgagaagc atcagcagtt gcgtgccaga
      661 tcccattcag agctcctgaa gaagtctaca tttgcgcgcc tgccgcccta caggtataga
      721 ttccgaagac ggtcaagttc tcgctccact gaacccagat ctcgagacct ttctcccatc
      781 agcaaaggct tccacaccat cccttccacc gacatctcca tgttcaccct ctcccgggac
      841 ccctctaagc ttaccatggg gacccttctc aactctgacc gggaccatgc ttttctacag
      901 ttccacaact ccacacccaa agagttcaaa gagtcattgc ataacaatcc ggccaacaga
      961 cgtaccacgc ctgtctgagc tgacctctga cctctgcccc gccgcccagc acagccttgg
     1021 gggaagtgta cacagatgtc tctaaggttg catggcatgg tcctcgtgat ggtatcactt
     1081 cttacaaaga acgaaaccaa atggactcag ccccctccca cagtggtccc tcatccccca
     1141 gaccttaacc cgtccacttc ccccgacttt tctcgctggt cccttaatgt tacccctctc
     1201 tgtgtatctg tgccaagtgt tttcttttct tccttctttc ctggaaggac cacgacattc
     1261 ttccctcctt gggaaaggac ttgactaaag tcgaaggtgc agtcatagca tcgggggatt
     1321 tccaaatccc ctatcagttg tatgcatagg tgttcccatt gtccacccac acaaactctc
     1381 tgtgaaaccc accacacagg tggctccgag agaggcattc acctttaagt gttagaaaaa
     1441 catgaccaga aatcagatgt cagtgccccg aagcagctca tgtaataagc actcgtgtta
     1501 ttaaaggttt ttgccttgta accaaaaaaa aaaaaaaaaa
//
