LOCUS       NM_001081023            6049 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus calcium channel, voltage-dependent, L type, alpha 1S
            subunit (Cacna1s), transcript variant 2, mRNA.
ACCESSION   NM_001081023 XM_001002706
VERSION     NM_001081023.3
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6049)
  AUTHORS   Coren,L., Zaffryar-Eilot,S., Odeh,A., Kaganovsky,A. and Hasson,P.
  TITLE     Fibroblast diversification is an embryonic process dependent on
            muscle contraction
  JOURNAL   Cell Rep 43 (12), 115034 (2024)
   PUBMED   39636726
REFERENCE   2  (bases 1 to 6049)
  AUTHORS   Kaplan,M.M., Zeidler,M., Knapp,A., Holzl,M., Kress,M., Fritsch,H.,
            Krogsdam,A. and Flucher,B.E.
  TITLE     Spatial transcriptomics in embryonic mouse diaphragm muscle reveals
            regional gradients and subdomains of developmental gene expression
  JOURNAL   iScience 27 (6), 110018 (2024)
   PUBMED   38883818
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6049)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 6049)
  AUTHORS   Zheng,Y., Zhao,C., Song,Q., Xu,L., Zhang,B., Hu,G., Kong,X., Li,S.,
            Li,X., Shen,Y., Zhuang,L., Wu,M., Liu,Y. and Zhou,Y.
  TITLE     Histone methylation mediated by NSD1 is required for the
            establishment and maintenance of neuronal identities
  JOURNAL   Cell Rep 42 (12), 113496 (2023)
   PUBMED   37995181
REFERENCE   5  (bases 1 to 6049)
  AUTHORS   Dos Santos,M., Shah,A.M., Zhang,Y., Bezprozvannaya,S., Chen,K.,
            Xu,L., Lin,W., McAnally,J.R., Bassel-Duby,R., Liu,N. and Olson,E.N.
  TITLE     Opposing gene regulatory programs governing myofiber development
            and maturation revealed at single nucleus resolution
  JOURNAL   Nat Commun 14 (1), 4333 (2023)
   PUBMED   37468485
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6049)
  AUTHORS   Chaudhari,N.
  TITLE     A single nucleotide deletion in the skeletal muscle-specific
            calcium channel transcript of muscular dysgenesis (mdg) mice
  JOURNAL   J Biol Chem 267 (36), 25636-25639 (1992)
   PUBMED   1281468
REFERENCE   7  (bases 1 to 6049)
  AUTHORS   Chin,H., Krall,M., Kim,H.L., Kozak,C.A. and Mock,B.
  TITLE     The gene for the alpha 1 subunit of the skeletal muscle
            dihydropyridine-sensitive calcium channel (Cchl1a3) maps to mouse
            chromosome 1
  JOURNAL   Genomics 14 (4), 1089-1091 (1992)
   PUBMED   1335956
REFERENCE   8  (bases 1 to 6049)
  AUTHORS   Powell,J.A., Friedman,B. and Cossi,A.
  TITLE     Tissue culture study of murine muscular dysgenesis: role of
            spontaneous action potential generation in the regulation of muscle
            maturation
  JOURNAL   Ann N Y Acad Sci 317, 550-570 (1979)
   PUBMED   289331
REFERENCE   9  (bases 1 to 6049)
  AUTHORS   Essien,F.B., Jorgensen,A.O., Kalnins,V.I., Zubrzycka,E. and
            MacLennan,D.H.
  TITLE     The biosynthesis and localization of sarcoplasmic reticulum
            proteins in dysgenic (mdg/mdg) mouse cells
  JOURNAL   Lab Invest 37 (6), 562-568 (1977)
   PUBMED   146110
REFERENCE   10 (bases 1 to 6049)
  AUTHORS   Yao,M.L. and Essien,F.B.
  TITLE     DNA synthesis and the cell cycle in cultures of normal and mutant
            (mdg/mdg) embryonic mouse muscle cells
  JOURNAL   Dev Biol 45 (1), 166-175 (1975)
   PUBMED   1237429
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124375.5 and AC124550.4.
            
            On Mar 24, 2022 this sequence version replaced NM_001081023.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN00849375, SAMN01164137
                              [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-242               AC124375.5         109310-109551
            243-348             AC124375.5         111078-111183
            349-488             AC124375.5         125420-125559
            489-631             AC124375.5         127133-127275
            632-784             AC124375.5         127409-127561
            785-990             AC124375.5         130006-130211
            991-1094            AC124375.5         131566-131669
            1095-1240           AC124375.5         133226-133371
            1241-1322           AC124375.5         134128-134209
            1323-1483           AC124375.5         135978-136138
            1484-1709           AC124375.5         140714-140939
            1710-1917           AC124375.5         141791-141998
            1918-2038           AC124375.5         143183-143303
            2039-2153           AC124375.5         143823-143937
            2154-2247           AC124375.5         144802-144895
            2248-2317           AC124375.5         145519-145588
            2318-2450           AC124375.5         148197-148329
            2451-2580           AC124375.5         149086-149215
            2581-2640           AC124375.5         149759-149818
            2641-2747           AC124375.5         151380-151486
            2748-2835           AC124375.5         151962-152049
            2836-2943           AC124375.5         152269-152376
            2944-2996           AC124375.5         153577-153629
            2997-3143           AC124375.5         153864-154010
            3144-3345           AC124375.5         154671-154872
            3346-3504           AC124375.5         155031-155189
            3505-3615           AC124375.5         157099-157209
            3616-3699           AC124375.5         157978-158061
            3700-3756           AC124550.4         27127-27183
            3757-3885           AC124550.4         28005-28133
            3886-3951           AC124550.4         28341-28406
            3952-4043           AC124550.4         28959-29050
            4044-4203           AC124550.4         29574-29733
            4204-4331           AC124550.4         30637-30764
            4332-4428           AC124550.4         33423-33519
            4429-4531           AC124550.4         34535-34637
            4532-4633           AC124550.4         35467-35568
            4634-4758           AC124550.4         35840-35964
            4759-4887           AC124550.4         37705-37833
            4888-5138           AC124550.4         38482-38732
            5139-5224           AC124550.4         40164-40249
            5225-5331           AC124550.4         40893-40999
            5332-5475           AC124550.4         41227-41370
            5476-6049           AC124550.4         41514-42087
FEATURES             Location/Qualifiers
     source          1..6049
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 59.55 cM"
     gene            1..6049
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /note="calcium channel, voltage-dependent, L type, alpha
                     1S subunit"
                     /db_xref="GeneID:12292"
                     /db_xref="MGI:MGI:88294"
     exon            1..242
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..5649
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /note="isoform 2 is encoded by transcript variant 2;
                     dihydropyridine receptor alpha 1S; voltage-dependent
                     L-type calcium channel subunit alpha-1S; voltage-gated
                     calcium channel subunit alpha Cav1.1; muscle dysgenesis"
                     /codon_start=1
                     /product="voltage-dependent L-type calcium channel subunit
                     alpha-1S isoform 2"
                     /protein_id="NP_001074492.1"
                     /db_xref="CCDS:CCDS35724.1"
                     /db_xref="GeneID:12292"
                     /db_xref="MGI:MGI:88294"
                     /translation="MEPPSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKAC
                     ISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAA
                     MKIIAYGFLFHQDAYLRSGWNVLDFIIVFLGVFTVILEQVNIIQTNTAPMSSKGAGLD
                     VKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELF
                     KGKMHKTCYFIGTDIVATVENEKPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFD
                     NFGFSMLTVYQCISMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLS
                     GEFTKEREKAKSRGTFQKLREKQQLEEDLRGYMSWITQGEVMDVDDLREGKLSLDEGG
                     SDTESLYEIEGLNKIIQFIRHWRQWNRVFRWKCHDLVKSKVFYWLVILIVALNTLSIA
                     SEHHNQPLWLTHLQDVANRVLLTLFTIEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGI
                     LEILLVESGAMSPLGISVLRCIRLLRLFKITKYWTSLSNLVASLLNSIRSIASLLLLL
                     FLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWNSVMYNGI
                     MAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEERK
                     RRKMSKGLPDKSEEERATVTKKLEQKSKGEGIPTTAKLKIDEFESNVNEVKDPYPSAD
                     FPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNA
                     TWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFTVEIVLKMTTYGA
                     FLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGL
                     KHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMTEEECRGYY
                     YIYKDGDPTQIELRPRQWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNEED
                     TGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQC
                     VQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSEQM
                     NHISDILNVAFTIIFTLEMVLKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDT
                     FLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIK
                     SFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
                     TGEAWQEILLACSYGKLCDPESDYAPGEEHTCGTNFAYYYFISFYMLCAFLIINLFVA
                     VIMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFG
                     KFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAII
                     KKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDT
                     VQIQAGLRTIEEEAAPEIHRAISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDN
                     FLERTNSLPPVMANQRPLQFAEIEMEELESPVFLEDFPQNPGTHPLARANTNNANANV
                     AYGNSSHRNNPVFSSICYEREFLGEADMPVTREGPLSQPCRASGPHSRSHVDKLKRPM
                     TQRGMPEGQVPPSPCQVTGAKAEHPVQKEGKGPTSRFLETPNSRNFEEHVPRNSAHRC
                     TAPATAMLIQEALVRGGLDSLAADANFVMATGQALADACQMEPEEVEVAATELLKQES
                     PEGGAVPWEP"
     exon            243..348
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            349..488
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            489..631
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            632..784
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            785..990
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            991..1094
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            1095..1240
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1322
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            1323..1483
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            1484..1709
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            1710..1917
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            1918..2038
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            2039..2153
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            2154..2247
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            2248..2317
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            2318..2450
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            2451..2580
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            2581..2640
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            2641..2747
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            2748..2835
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            2836..2943
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            2944..2996
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            2997..3143
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            3144..3345
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            3346..3504
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            3505..3615
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            3616..3699
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            3700..3756
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            3757..3885
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            3886..3951
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            3952..4043
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            4044..4203
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            4204..4331
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            4332..4428
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            4429..4531
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            4532..4633
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            4634..4758
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            4759..4887
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            4888..5138
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            5139..5224
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            5225..5331
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            5332..5475
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     exon            5476..6049
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6022..6027
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /note="hexamer: ATTAAA"
     polyA_site      6049
                     /gene="Cacna1s"
                     /gene_synonym="Cav1.1; Cchl1a3; DHPR; DHPR alpha1s; fmd;
                     mdg; sj"
                     /note="major polyA site"
ORIGIN      
        1 agtcaggtcc agtccccaag gtgggggcac tggggacaca gggaggagag ggcagtgggc
       61 tgggggaaga gaggggtgtc agggaaagcc atggagccgc cctcacccca ggacgagggc
      121 ctgaggaaga agcagccgaa gaaacctgtt cctgagattc tgccgaggcc cccgcgggcc
      181 ttgttctgcc tgactctaca gaaccccctg aggaaggcct gcatcagcat cgtggaatgg
      241 aaacccttcg agaccatcat cttgctcacc atctttgcca actgtgtggc cctggcagtg
      301 tacctgccca tgccagagga tgacaacaac actctgaacc tcggcctgga gaaactggag
      361 tacttcttcc tcattgtctt ctccattgaa gccgccatga agatcatagc ctacggcttc
      421 ctattccatc aggatgcata cctgcgcagt ggctggaacg ttctggactt catcattgtc
      481 tttctggggg tcttcactgt gattctggaa caagttaaca tcattcaaac caacacggcc
      541 cccatgagca gcaaaggagc cggcttggat gtgaaggccc ttcgagcatt ccgcgtgctc
      601 agacccctgc ggctggtgtc gggggtgccc agtcttcagg tggtcctcaa ctccatcttc
      661 aaggccatgc tccccctgtt ccacattgcc ctgctcgtcc tcttcatggt catcatctac
      721 gccatcattg ggctggagct cttcaaaggc aagatgcaca agacttgcta cttcattggg
      781 acagacattg tagccacagt tgagaatgag aaaccatcac cctgtgctag aactggctct
      841 gggcgtccct gcaccatcaa tggcagcgag tgccgaggag gttggccagg acccaaccac
      901 ggcatcaccc acttcgacaa ctttggcttc tctatgctca ctgtgtatca atgcatctcc
      961 atggaggggt ggactgatgt cctgtactgg gtcaacgatg ccatcgggaa tgagtggccc
     1021 tggatctact ttgtcaccct cattctgctg ggctccttct tcatcctcaa cctggtgctg
     1081 ggtgtcctga gtggagaatt caccaaagag cgagagaagg ccaagtccag gggaaccttc
     1141 caaaagctcc gagagaaaca gcagctggag gaggacctcc gtggttacat gagctggatc
     1201 acacagggcg aggtcatgga cgtggacgac ttgagagaag gcaagctgtc tttggatgaa
     1261 gggggatcag acacagagag cttgtatgaa atcgaaggct tgaacaaaat catccagttc
     1321 attcggcact ggcgacagtg gaatcgcgtc ttccgctgga agtgccatga cctagtgaaa
     1381 tccaaggtct tctattggct ggtgatcctg atcgttgccc taaacaccct gtccattgcc
     1441 tcggagcacc acaaccagcc actctggttg acccatttgc aagatgttgc caaccgcgtg
     1501 ttgctgaccc tcttcaccat cgaaatgctc atgaagatgt acgggctggg cctgcgccag
     1561 tacttcatgt ccatcttcaa ccgcttcgac tgcttcgtgg tgtgcagcgg catcctggag
     1621 atcctgctgg tggagtcggg agccatgtcg cccctgggca tctctgtgct ccgctgtatc
     1681 cgcctcctga ggctcttcaa gatcaccaag tactggacat cgctgagcaa cctggtggcc
     1741 tcactgctca actccatccg ctccattgct tccctcttgc tgctgctctt tctcttcatc
     1801 atcatctttg ccctgctggg catgcagctc tttggaggca gatatgactt tgaagacaca
     1861 gaagtacgac gaagcaactt tgacaacttc ccccaggccc tcatcagtgt cttccaggtc
     1921 ctgacgggtg aagactggaa ctctgtgatg tacaatggga tcatggctta cggaggtccg
     1981 acctaccctg gtgtgctggt gtgcatttat ttcatcatcc ttttcgtctg tggcaactac
     2041 atccttctca acgtcttcct ggctattgct gtggacaacc tggcagaggc agagagtctg
     2101 acatctgccc aaaaggccaa ggctgaggag agaaagcgca ggaagatgtc gaaagggctc
     2161 ccagacaagt cagaagagga gagggccacg gtgaccaaga aactggagca gaagtccaag
     2221 ggtgaaggca tccccaccac cgccaagctg aaaatcgatg agtttgaatc aaacgttaat
     2281 gaggtgaaag acccctaccc ttcggctgac ttcccagggg acgatgagga agatgagccc
     2341 gagatcccag tgagcccccg accacgccct ctggccgagc tgcagctgaa agagaaagca
     2401 gtgcccatcc cggaggctag ctccttcttc atcttcagtc ccaccaacaa gatccgtgtc
     2461 ctgtgtcacc gcattgtcaa tgccacctgg ttcaccaact tcatcctgct cttcatcctg
     2521 ctcagcagtg ccgccctggc cgctgaggat cccatccggg ccgactccat gaggaatcag
     2581 atcctcgagt attttgatta tgtgttcact gctgttttca cggtggagat tgtccttaag
     2641 atgaccacct atggagcctt cctgcacaaa ggctccttct gccgcaacta cttcaacatc
     2701 ctggacctgc tggtggtggc tgtgtccctc atctccatgg gcctcgagtc cagcgccatc
     2761 tccgtggtga agatcttaag ggttctgaga gtgctgagac cactccgggc cataaacaga
     2821 gccaaagggt tgaagcacgt ggtgcagtgc gtgtttgttg ccattcgcac catcgggaac
     2881 atcgtgctgg tcaccacgct cctgcagttc atgtttgcgt gcattggagt gcagcttttc
     2941 aagggaaagt tctacagctg caatgactta tccaagatga ctgaagagga atgcaggggc
     3001 tactactaca tatacaagga tggagacccc actcagatag agctgcgtcc ccgccagtgg
     3061 atacacaatg acttccactt tgacaatgta ctctccgcta tgatgtcact cttcacggtc
     3121 tccaccttcg agggttggcc tcagctactg tacaaggcca tagactcaaa tgaggaggac
     3181 accggccctg tctacaacaa ccgagtggag atggccatct tcttcattat ctacatcatc
     3241 ctcattgcct tcttcatgat gaacatcttt gtgggctttg tcatcgttac cttccaggaa
     3301 cagggagaga ctgagtataa gaactgtgag ctcgacaaga accagcgcca atgcgtacag
     3361 tatgccctga aggcccgccc actgaggtgt tacatcccca aaaacccata ccagtatcag
     3421 gtgtggtatg tcgtcacttc ctcctacttt gaatacctga tgtttgctct catcatgctc
     3481 aatactatct gcctgggcat gcagcattac aaccagtcgg aacagatgaa ccacatctca
     3541 gacattctca acgtggcttt caccatcatc ttcaccctgg agatggtcct caagctcata
     3601 gctttcaagc ccaggggcta ttttggagat ccttggaatg tgtttgactt cctaatcgtc
     3661 atcggcagca tcattgacgt catcctgagc gagatcgata ctttcctggc ctccagcggg
     3721 ggactgtatt gcctgggtgg aggctgcggg aacgttgacc cagatgagag cgcccgtatc
     3781 tccagtgcct tcttccgcct gttccgggtc atgagactgg tcaagctgct gaaccgggcg
     3841 gagggtgtgc gcaccctgct gtggacattc atcaagtcct tccaggccct gccgtacgtg
     3901 gctttgctga tcgtgatgct cttcttcatc tacgcggtca tcggcatgca gatgttcggg
     3961 aagatcgcca tggtggacgg gacgcagata aaccggaaca acaacttcca gactttccca
     4021 caggccgtgc tgctgctctt caggtgtgcc acaggggaag cctggcaaga gatcctgctg
     4081 gcctgcagct atgggaagct gtgtgacccg gagtctgact acgcacccgg ggaggagcat
     4141 acatgcggca ccaacttcgc ctactactac ttcatcagtt tctacatgct ctgcgccttc
     4201 ctgatcatca acctctttgt ggctgtcatc atggacaact ttgattacct cacaagggac
     4261 tggtccattc tgggccctca ccacctggac gagttcaagg ccatttgggc tgagtacgac
     4321 ccggaggcta agggcaggat caagcacctg gatgtggtga ccctgctgag gaggattcag
     4381 ccccctctgg gctttgggaa gttctgccca cacagggtag catgtaagag gctggtgggc
     4441 atgaacatgc ccctgaacag cgatggcaca gtcaccttta atgccacact atttgccctg
     4501 gtgcgcacag ccctcaagat caagacagaa ggcaactttg aacaagctaa cgaggagctg
     4561 agagccatca tcaagaagat ctggaagaga accagcatga agctcttgga ccaagtcatc
     4621 cctccaatag gagatgatga ggtgacagta gggaaattct atgccacatt cctcatccag
     4681 gagcacttcc ggaagttcat gaagcgccag gaggaatatt atgggtatcg acccaaaaag
     4741 gacacagttc agatacaggc tggattacgg accatagagg aagaggcagc tcctgagatc
     4801 caccgtgcca tctctggaga cctgacagca gaggaggaac tggagagggc catggtagag
     4861 gctgccatgg aggaggggat attccggagg acgggaggcc tgtttggtca agtggacaac
     4921 ttcctggaaa ggaccaactc tctgccccct gtcatggcca accaaagacc cctccaattt
     4981 gctgaaatag agatggaaga gctggagtca ccagtcttct tggaggactt ccctcagaac
     5041 ccaggcaccc accctcttgc tcgtgccaat accaacaacg ccaatgccaa tgttgcctat
     5101 ggcaacagca gccatagaaa caacccagtg ttttccagca tctgctatga acgggagttc
     5161 ttgggagagg cggacatgcc tgttaccaga gaaggacccc tcagtcagcc ctgcagggcc
     5221 tcaggacctc acagcagatc tcatgtggac aaactgaaaa gaccgatgac ccagagagga
     5281 atgcctgaag gccaggtgcc tccttccccg tgccaggtaa caggggcaaa agcagagcat
     5341 cctgtgcaga aagagggaaa gggccccacg tcacggtttc tggaaacacc caacagcagg
     5401 aactttgagg agcacgttcc caggaattcg gctcacaggt gcacggctcc agctactgcc
     5461 atgctgatcc aggaggctct ggttcgagga ggactagact ccttagcagc agatgctaac
     5521 ttcgtcatgg caacaggcca ggccctggca gatgcctgcc agatggaacc agaggaagtc
     5581 gaggtggcag caacagagct actgaagcaa gaatccccag agggcggggc cgtgccctgg
     5641 gagccttgag cctcaggtcc tcccctgggc cgcctgaatc tgcgttgggg ctcccaaacg
     5701 acccttatta ctcccagatg tgaggcctat acagaatgac acaagcttag aaataccatg
     5761 accaaaagcc agaaagtgct ggagtggaga agtaggttag cccagcttag cagcctcccc
     5821 tggcccctca gtagccagct gtatggactg agtagcggtg gtcgggaacc acctcaacca
     5881 ggcaggaggc catgggtggg cagggccggc ccttctcctc atcagcaaga agcaggattc
     5941 ggcagggctt gtgtggccat tcacaaaggc ctgatcggtg ccagggtctg tctgtcataa
     6001 agccactcta tctagctgga cattaaagtc tccaggcctg actttggca
//
