LOCUS       NM_001083616            9075 bp    mRNA    linear   ROD 18-MAR-2025
DEFINITION  Mus musculus calcium channel, voltage-dependent, L type, alpha 1D
            subunit (Cacna1d), transcript variant 2, mRNA.
ACCESSION   NM_001083616
VERSION     NM_001083616.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9075)
  AUTHORS   Shen,C.L., Tsai,Y.Y., Chou,S.J., Chang,Y.M. and Tarn,W.Y.
  TITLE     RBM4-mediated intron excision of Hsf1 induces BDNF for cerebellar
            foliation
  JOURNAL   Commun Biol 7 (1), 1712 (2024)
   PUBMED   39738787
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9075)
  AUTHORS   Zhai,S., Otsuka,S., Xu,J., Clarke,V.R.J., Tkatch,T., Wokosin,D.,
            Xie,Z., Tanimura,A., Agarwal,H.K., Ellis-Davies,G.C.R.,
            Contractor,A. and Surmeier,D.J.
  TITLE     Ca2+-dependent phosphodiesterase 1 regulates the plasticity of
            striatal spiny projection neuron glutamatergic synapses
  JOURNAL   Cell Rep 43 (8), 114540 (2024)
   PUBMED   39058595
REFERENCE   3  (bases 1 to 9075)
  AUTHORS   Belghazi,M., Iborra,C., Toutendji,O., Lasserre,M., Debanne,D.,
            Goaillard,J.M. and Marqueze-Pouey,B.
  TITLE     High-Resolution Proteomics Unravel a Native Functional Complex of
            Cav1.3, SK3, and Hyperpolarization-Activated Cyclic
            Nucleotide-Gated Channels in Midbrain Dopaminergic Neurons
  JOURNAL   Cells 13 (11), 944 (2024)
   PUBMED   38891076
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 9075)
  AUTHORS   Kim,S.H. and Kim,C.H.
  TITLE     Neuronal IGF-1 overexpression restores hippocampal newborn cell
            survival and recent CFC memory consolidation in Cav1.3 knock-out
            mice
  JOURNAL   Brain Res 1825, 148712 (2024)
   PUBMED   38097125
REFERENCE   5  (bases 1 to 9075)
  AUTHORS   Vandael,D.H., Mahapatra,S., Calorio,C., Marcantoni,A. and
            Carbone,E.
  TITLE     Cav1.3 and Cav1.2 channels of adrenal chromaffin cells: emerging
            views on cAMP/cGMP-mediated phosphorylation and role in pacemaking
  JOURNAL   Biochim Biophys Acta 1828 (7), 1608-1618 (2013)
   PUBMED   23159773
  REMARK    Review article
REFERENCE   6  (bases 1 to 9075)
  AUTHORS   Adamson,M.C., Dennis,C., Delaney,S., Christiansen,J., Monkley,S.,
            Kozak,C.A. and Wainwright,B.
  TITLE     Isolation and genetic mapping of two novel members of the murine
            Wnt gene family, Wnt11 and Wnt12, and the mapping of Wnt5a and
            Wnt7a
  JOURNAL   Genomics 24 (1), 9-13 (1994)
   PUBMED   7896292
REFERENCE   7  (bases 1 to 9075)
  AUTHORS   Zhang-Keck,Z.Y., Srivastava,M., Kozak,C.A., Caohuy,H., Shirvan,A.,
            Burns,A.L. and Pollard,H.B.
  TITLE     Genomic organization and chromosomal localization of the mouse
            synexin gene
  JOURNAL   Biochem J 301 (Pt 3) (Pt 3), 835-845 (1994)
   PUBMED   8053909
REFERENCE   8  (bases 1 to 9075)
  AUTHORS   Hanley-Hyde,J., Mushinski,J.F., Sadofsky,M., Huppi,K., Krall,M.,
            Kozak,C.A. and Mock,B.
  TITLE     Expression of murine cyclin B1 mRNAs and genetic mapping of related
            genomic sequences
  JOURNAL   Genomics 13 (4), 1018-1030 (1992)
   PUBMED   1387105
REFERENCE   9  (bases 1 to 9075)
  AUTHORS   Chin,H.M., Kozak,C.A., Kim,H.L., Mock,B. and McBride,O.W.
  TITLE     A brain L-type calcium channel alpha 1 subunit gene (CCHL1A2) maps
            to mouse chromosome 14 and human chromosome 3
  JOURNAL   Genomics 11 (4), 914-919 (1991)
   PUBMED   1664412
REFERENCE   10 (bases 1 to 9075)
  AUTHORS   Perez-Reyes,E., Wei,X.Y., Castellano,A. and Birnbaumer,L.
  TITLE     Molecular diversity of L-type calcium channels. Evidence for
            alternative splicing of the transcripts of three non-allelic genes
  JOURNAL   J Biol Chem 265 (33), 20430-20436 (1990)
   PUBMED   2173707
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK147415.1, AJ437291.1,
            AK032552.1 and BP761485.1.
            
            On Nov 5, 2014 this sequence version replaced NM_001083616.1.
            
            Summary: This gene encodes a pore-forming subunit of the L-type,
            voltage-activated calcium channel family. These channels have been
            found to play a role in heart and smooth muscle contraction and in
            the transmission of auditory information. Homozygous knockout mice
            for this gene exhibit deafness and heart defects. These channels
            have also been linked to mitochondrial oxidative stress in a mouse
            model of Parkinson's disease. Alternative splicing results in
            multiple transcript variants encoding different isoforms. [provided
            by RefSeq, Nov 2014].
            
            Transcript Variant: This variant (2) lacks two alternate in-frame
            exons in the coding region, compared to variant 3. This results in
            a shorter protein (isoform 2), compared to isoform 3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ437291.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1611              AK147415.1         2-1612
            1612-1828           AJ437291.1         1117-1333
            1829-1973           AK147415.1         1830-1974
            1974-2237           AJ437291.1         1479-1742
            2238-3258           AK147415.1         3289-4309
            3259-5711           AJ437291.1         2764-5216
            5712-8563           AK147415.1         6808-9659
            8564-9054           AK032552.1         3012-3502
            9055-9075           BP761485.1         1-21                c
FEATURES             Location/Qualifiers
     source          1..9075
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 18.43 cM"
     gene            1..9075
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /note="calcium channel, voltage-dependent, L type, alpha
                     1D subunit"
                     /db_xref="GeneID:12289"
                     /db_xref="MGI:MGI:88293"
     exon            1..562
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     CDS             496..6930
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /note="isoform 2 is encoded by transcript variant 2;
                     voltage-dependent L-type calcium channel subunit alpha-1D;
                     alpha 1 E; voltage-gated calcium channel subunit alpha
                     Cav1.3; calcium channel, L type, alpha-1 polypeptide;
                     Cav1.3alpha1"
                     /codon_start=1
                     /product="voltage-dependent L-type calcium channel subunit
                     alpha-1D isoform 2"
                     /protein_id="NP_001077085.1"
                     /db_xref="CCDS:CCDS36847.1"
                     /db_xref="GeneID:12289"
                     /db_xref="MGI:MGI:88293"
                     /translation="MMMMMMMKKMQHQRQHQEDHANEANYARGTRLPISGEGPTSQPN
                     SSKQTVLSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRP
                     ARALFCLSLNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHN
                     LEKVEYAFLIIFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLT
                     KETEGGNHSSGKSGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIAL
                     LVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGNGRQCTANGTECR
                     SGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVYFVSLIIL
                     GSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDP
                     ENEEEGGEEGKRNTSMPTSETESVNTENVSGEGETQGCCGTLCQAISKSKLSRRWRRW
                     NRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALF
                     TCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELELMSPLGVSVFRCVRLL
                     RIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQ
                     TKRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGN
                     YILLNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIAN
                     SDNKVTIDDYQEDAEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEK
                     IAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSF
                     RNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGI
                     QSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFA
                     CIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVL
                     SAMMALFTVSTFEGWPALLYKAIDSNGENVGPVYNYRVEISIFFIIYIIIVAFFMMNI
                     FVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNS
                     SPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPK
                     GYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNRISITFFRLFRVMRLVKLLSRGEG
                     IRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFP
                     QAVLLLFRCATGEAWQEIMLACLPGKLCDPDSDYNPGEEYTCGSNFAIVYFISFYMLC
                     AFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLL
                     RRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLE
                     QANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQ
                     GLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEDSKPEEEDVFKRNGA
                     LLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSMPPASDTEKPLFPPAGNSGCHNHHN
                     HNSIGKQAPTSTNANLNNANMSKAAHGKPPSIGNLEHVSENGHYSCKHDRELQRRSSI
                     KRTRYYETYIRSESGDEQFPTICREDPEIHGYFRDPRCLGEQEYFSSEECCEDDSSPT
                     WSRQNYNYYNRYPGSSMDFERPRGYHHPQGFLEDDDSPTGYDSRRSPRRRLLPPTPPS
                     HRRSSFNFECLRRQSSQDDVLPSPALPHRAALPLHLMQQQIMAVAGLDSSKAQKYSPS
                     HSTRSWATPPATPPYRDWSPCYTPLIQVDRSESMDQVNGSLPSLHRSSWYTDEPDISY
                     RTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADA
                     CDLTIDEMESAASTLLNGSVCPRANGDMGPISHRQDYELQDFGPGYSDEEPDPGREEE
                     DLADEMICITTL"
     exon            563..872
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            873..978
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1118
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1261
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..1414
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            1415..1611
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1715
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            1716..1885
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..1973
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            1974..2000
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            2001..2161
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            2162..2387
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            2388..2595
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            2596..2716
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            2717..2831
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            2832..2901
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            2902..2968
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            2969..3116
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            3117..3246
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            3247..3306
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            3307..3413
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            3414..3501
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            3502..3609
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            3610..3662
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            3663..3809
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            3810..4011
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            4012..4170
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            4171..4281
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            4282..4365
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            4366..4494
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            4495..4560
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            4561..4652
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            4653..4812
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            4813..4940
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            4941..5037
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            5038..5140
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            5141..5242
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            5243..5373
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            5374..5487
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            5488..5852
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            5853..5879
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            5880..6029
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            6030..6193
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            6194..6315
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            6316..6636
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     exon            6637..9062
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9038..9043
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /note="hexamer: ATTAAA"
     polyA_site      9062
                     /gene="Cacna1d"
                     /gene_synonym="8430418G19Rik; Cach3; Cacn4; Cacnl1a2;
                     Cav1.3; Cchl1a; Cchl1a2; D-LTCC"
                     /note="major polyA site"
ORIGIN      
        1 gcggtcccga gccagcggcg gcgcgggcgg cggcggcggc ggcggggcac cgggcaccgc
       61 ggcgggcggg cggacgggcg gcatgggggg cgcgccgagc ggcccggcag gccgggcggg
      121 caccaccacg gtgtccctcc gctagaggag gggaccaagc caattctcct ttgcagtaaa
      181 aaaaaataaa aaaaataaaa aattacatgt atatattact aagataatat atacatctga
      241 ttttattttt tacaaaaagt ttattttgct ccatttttca aaaaaaaaag aaggagcgtg
      301 ggtggcaggc ggtttttata aattatcttt atttttggtt atttgtctct gtccttcccc
      361 accccctgct gaagcgaaaa taagggcagg gaccgcggct cctacctatc cgtaacctcc
      421 catatccgtt cctccccctc cctaaccctg agcatagtgc cctgcacaca gtaggcgctc
      481 aataaatgtt cgtggatgat gatgatgatg atgatgaaaa aaatgcaaca tcaacggcag
      541 caccaagagg accatgcgaa cgaggcaaac tatgcaagag gcaccagact ccctatttct
      601 ggtgaaggac caacttctca gcccaacagc tccaagcaaa ctgtcctatc ttggcaagct
      661 gcaatcgatg ctgctagaca ggccaaggcc gcccagacca tgagcacctc tgcaccccca
      721 cctgtaggat ctctctccca aagaaaacgt cagcaatacg ccaagagcaa aaaacagggt
      781 aactcgtcta acagccgacc tgcccgtgcc cttttctgtt tatccctcaa taaccccatc
      841 cgaagagcct gcattagtat agtggaatgg aaaccatttg acatatttat attattggct
      901 atttttgcca attgtgtggc cttagctatt tacatcccat tccctgaaga tgattctaat
      961 tcaacaaatc ataacttgga aaaagtagaa tatgccttcc tgattatttt tacagtggag
     1021 acatttctga agattatagc gtatggactg ttgctgcatc ctaatgctta cgttaggaat
     1081 ggatggaatt tactggattt tgttatagta attgtaggat tgtttagtgt aattctggaa
     1141 caattaacca aagaaacaga aggcgggaac cactctagtg gcaaatcagg aggctttgat
     1201 gtcaaagccc tccgtgcctt ccgagtgtta agaccacttc gacttgtatc aggagtgccc
     1261 agtttacaag ttgttctgaa ctccattata aaagccatgg tccccctcct tcacatagcc
     1321 cttttggtat tatttgtaat tatcatctat gctattatag gattggaact ttttattgga
     1381 aaaatgcaca aaacatgttt ttttgctgac tcagatatag tagctgaaga ggacccagct
     1441 ccgtgtgcgt tctcagggaa tggacgccag tgcaccgcca atggcacgga atgtaggagt
     1501 ggctgggttg gccccaatgg aggcatcact aactttgata actttgcctt tgccatgctc
     1561 actgtgttcc agtgcattac catggagggc tggacagatg tgctctactg ggttaatgat
     1621 gcgataggat gggaatggcc atgggtgtat tttgttagtc tgatcatcct tggctcattt
     1681 ttcgtcctta acctggttct tggtgtcctt agtggagaat tctccaagga aagagagaag
     1741 gctaaagctc gtggagattt ccagaagctt cgggaaaaac agcagctgga agaggacctc
     1801 aagggctacc tggactggat cacccaggca gaagacatcg atcccgagaa cgaggaggag
     1861 ggtggcgagg aaggcaaacg aaacactagc atgcccacca gcgagactga atctgtcaac
     1921 acagagaacg taagtggtga aggcgagacc cagggatgct gtggaactct ctgtcaggcc
     1981 atctcgaaat ccaaactcag ccgtcgatgg cgtcgctgga accggttcaa tcgcaggagg
     2041 tgcagggctg ccgtgaagtc tgtcacgttt tactggctgg tgattgtcct ggtgtttctc
     2101 aacactttaa ctatttcctc tgagcattac aatcagccag actggctgac acagattcaa
     2161 gacatcgcaa acaaagtcct cttggctctg ttcacctgtg agatgctggt gaagatgtac
     2221 agcctgggcc tccaggctta ctttgtctcc ctcttcaacc gcttcgattg ctttgtggtg
     2281 tgtgggggca tcaccgaaac catcctggtg gaactggagc tcatgtctcc cctgggggtc
     2341 tccgtgttcc ggtgtgtgcg cctcctgaga atcttcaaag tgaccaggca ctggacctcc
     2401 ctgagcaact tggtggcatc cttgttaaac tccatgaagt ccatcgcctc tctgctgtta
     2461 ctcctcttcc tcttcatcat catcttctcc ttgctgggga tgcagttgtt tggtgggaag
     2521 tttaattttg acgagactca aaccaagcga agcacctttg acaactttcc gcaagcactc
     2581 ctgacggtgt tccagatcct gacaggtgaa gactggaatg cggtgatgta tgacggcatc
     2641 atggcctatg gaggcccttc ctcttccggg atgattgtct gtatctactt catcatcctt
     2701 ttcatctgtg gtaactatat cctgctgaat gtcttcttgg ccatcgctgt ggacaatttg
     2761 gctgatgctg aaagtctgaa cactgctcag aaagaggaag ctgaagaaaa agaaaggaaa
     2821 aagattgcca gaaaagaaag cctagaaaac aaaaagaaca acaaaccaga agtcaaccag
     2881 atagccaaca gtgacaacaa ggttacaatt gatgattatc aggaagatgc tgaagacaag
     2941 gacccttacc cgccctgtga tgtgccagta ggtgaagagg aagaggagga ggaagaggat
     3001 gagcccgaag ttcctgctgg tccccgccct cgcagaatct cagagttgaa catgaaggag
     3061 aagattgcgc ccatcccaga aggaagcgcc ttcttcattc ttagcaagac caacccgata
     3121 cgtgtgggtt gccacaagct cattaaccac cacatcttca ccaaccttat cctggtcttc
     3181 atcatgctga gcagcgctgc cctggctgca gaggacccca tccgtagcca ctcattccgc
     3241 aacacgatac tgggctactt tgactatgcc ttcacagcca tctttacggt tgaaatcctg
     3301 ttaaagatga caacttttgg agccttcttg cacaaagggg ctttctgcag gaactacttc
     3361 aatttgctgg acatgctggt tgttggggtg tcgctggtgt cctttgggat tcagtccagc
     3421 gccatctccg ttgtgaagat tctgagggtt ttgagggtct tgcggcctct cagagcaatc
     3481 aacagagcaa agggacttaa gcacgtggtc cagtgtgtct ttgtggccat ccgaaccatt
     3541 ggcaacatca tgatcgtcac gaccctgctc cagttcatgt ttgcatgcat tggggtccag
     3601 ctgttcaagg ggaagttcta ccgttgcaca gatgaagcca aaagtaaccc tgaggagtgc
     3661 agggggcttt tcattcttta taaggacggc gatgttgaca gtcctgtggt ccgtgagagg
     3721 atctggcaaa atagtgattt caattttgac aatgtccttt cggctatgat ggcgctgttc
     3781 acagtctcaa cttttgaggg ctggcccgcg ttgctgtaca aagctattga ttcaaacggt
     3841 gagaacgttg gtcctgtcta caactaccgt gtggagatct ccatcttctt catcatctac
     3901 atcatcatcg ttgccttctt catgatgaac atctttgtgg gcttcgtcat cgtcaccttc
     3961 caggaacagg gagaaaaaga gtataagaac tgtgagctgg acaaaaatca gcgtcagtgt
     4021 gttgaatatg ccttgaaagc acgcccctta aggagataca tccccaaaaa cccataccag
     4081 tacaagttct ggtatgtggt gaactcctcg cctttcgaat acatgatgtt cgtcctcatc
     4141 atgctcaaca cgctctgcct ggccatgcag cactatgagc agtccaagat gttcaatgat
     4201 gccatggaca ttctgaacat ggtcttcaca ggggtcttca ctgttgagat ggttttgaaa
     4261 gtcattgctt tcaagcccaa ggggtatttt agtgacgcct ggaacacgtt tgactccctc
     4321 atcgtaatcg gcagcattat agacgtggcc ctcagcgaag ccgacaactc tgaagagagc
     4381 aatagaatct ccatcacctt tttccgtctt ttccgagtga tgcggttggt gaaacttctc
     4441 agcagggggg aaggcatccg gacactgctg tggaccttca tcaagtcctt tcaggcgctg
     4501 ccgtatgttg ccctcctcat tgccatgctc ttcttcatct acgctgtcat aggcatgcag
     4561 atgtttggga aagttgccat gagagataac aaccagatca ataggaacaa caacttccag
     4621 acctttcctc aggcagtgct cctactcttc aggtgtgcaa caggggaagc ctggcaggag
     4681 atcatgcttg cctgcctccc aggaaagctg tgcgacccag actccgatta caacccagga
     4741 gaggagtaca cttgtgggag caactttgcc attgtctact tcatcagctt ttacatgctc
     4801 tgtgcattcc tgatcatcaa cctctttgtg gctgtcatca tggacaattt tgactatctg
     4861 actcgggact ggtctattct ggggcctcac cacttggacg aattcaaaag aatatggtca
     4921 gaatatgacc ctgaagcaaa gggaaggata aaacaccttg atgtggtcac tctgctccgg
     4981 cggatccagc ctcccctggg gtttggaaaa ttatgcccac accgagtagc atgtaagaga
     5041 ttggttgcca tgaacatgcc tctcaacagt gatgggacag tcatgttcaa tgcaaccctg
     5101 tttgctttgg tccggacagc tctcaagatc aagactgaag ggaacctgga gcaagctaat
     5161 gaagaactcc gagctgtgat caagaaaatc tggaagaaga caagcatgaa gctgcttgac
     5221 caagttgtcc ctccagctgg tgatgatgag gtaaccgtgg ggaagttcta tgccactttc
     5281 ctgatacagg actactttag gaaattcaag aaacggaaag agcaaggact ggtggggaag
     5341 taccctgcga agaacaccac gattgcccta caggcgggat taaggaccct gcatgacatt
     5401 gggccagaaa tccgacgggc tatatcctgt gacttgcaag atgacgagcc agaagactcc
     5461 aaaccagaag aagaagatgt attcaaaaga aatggtgccc tgcttggaaa ccatgtcaat
     5521 catgttaata gtgataggag agattccctt cagcagacca ataccaccca ccgtcccctg
     5581 catgtccaaa ggccttcaat gccacctgca agtgatactg agaaaccgct gtttcctcca
     5641 gcaggaaatt cggggtgtca taaccatcat aaccataatt ccatagggaa gcaagctccc
     5701 acctcaacaa atgccaatct caataatgcc aatatgtcca aagctgccca cggaaagccg
     5761 cccagcattg ggaaccttga gcatgtgtct gaaaatgggc attactcctg caagcatgat
     5821 cgagagcttc aaagaaggtc cagtattaaa agaacccgct attacgagac ttacattagg
     5881 tctgagtcag gagatgagca atttccaacc atttgccgtg aagatcctga gatacacggc
     5941 tacttccgag acccccgctg cttgggggaa caggagtatt tcagtagcga ggagtgctgt
     6001 gaggacgaca gctctcccac ctggagcagg caaaactaca actactacaa caggtaccca
     6061 ggcagctcca tggactttga gaggccccga ggctaccacc acccccaagg cttcttagaa
     6121 gatgatgact ctcccactgg ctatgattca cggagatctc cgaggagacg tcttctacct
     6181 cctaccccac catcccatcg gaggtcctcc ttcaactttg agtgtctgcg caggcaaagc
     6241 agccaagacg atgtccttcc atcgcctgcc ctgcctcacc gcgctgccct gcccctgcac
     6301 ctgatgcagc agcagatcat ggccgttgca ggcctagatt ccagtaaagc ccagaagtac
     6361 tcaccgagcc actctacccg gtcgtgggcc acccctccag caacccctcc ataccgagac
     6421 tggagcccat gctacacccc tttgatccag gtggaccgct cagaatctat ggaccaggtc
     6481 aatggcagcc tgccatccct acaccgaagc tcctggtaca cagatgaacc cgacatctcc
     6541 tataggactt tcacgccagc tagtctgact gtccccagca gcttccggaa caagaacagc
     6601 gacaagcaga ggagtgcaga cagcctggtg gaggcagtcc tgatatccga aggcttggga
     6661 cgctacgcga gggaccccaa atttgtctca gcgacaaaac atgagattgc cgatgcctgt
     6721 gacctaacca tagacgagat ggaaagtgct gccagcaccc tgctcaatgg cagtgtgtgt
     6781 cctcgagcca atggggacat gggccccatc tcccaccgcc aggactatga gctccaggac
     6841 tttggtcctg gctacagtga cgaggagcca gaccctgggc gagaggaaga ggacctggca
     6901 gatgagatga tttgcattac caccttgtag cccagtgagg gcaggctggc tccagccaga
     6961 gacgggcacg ggagggccag ggataaagtg cctcataatt aggaaagttt aggcactagt
     7021 tgggagaaaa acgctcaatt agacttttgt acaagtgatt tcatgcctca aggaagccat
     7081 aaacctggta ggagcaggtt ctgagcggcc tggcatgtgc tatgtcacat gctcaggccc
     7141 ggcctcagaa gacagtatat ctggcctgca cagaggccag agggctgccc aggagttggt
     7201 gtctcccatc cagggtgcat gcccatgccc ctttgcctgc agacatgaga gaggttaaag
     7261 gtgatgacag tcaccacgcc tgtgtcatta cctcaaccat tggtctagca tatcagacac
     7321 ccactgggcc tggcatatcc atttctgagc cccctccccc aacacactgg ttcctggttt
     7381 ctgtggagct gttctgaatg gtacacatca gaacccagcc actagtggtc acgacaaggg
     7441 gagtgggacc ggatcgtttt gttaagcgat gccagtttac ataagagacc atcactcaga
     7501 cggtcagttc tgtcacatta agggcaactg taaactggaa gagtaccgca cttgcaaacc
     7561 aggtaaaact tagatacgtt tagtttgttt aaaaattata gatttactgt acatgacttg
     7621 taatatacaa tttgtatttg taaagagatg gtctatattt tgtaattatc gtaccgtatt
     7681 tgaactgcag caatatccac gggtcctaac aatcgtagtt tcccacccaa acctagaaat
     7741 tattagtatt tttacttggg ctaaaaagaa ttaggagaat tagagccaat tctcacatgt
     7801 tcagtaaaag aatctttggg gataaacttt tgagttccta agaacttggc acttcagaac
     7861 ttttttctaa aatattttga gttactataa acctatcttt ccgtaagata tcaagttgac
     7921 taatttgcag tcttttcttt gggttctatg attttatagt gcacctccca cccacatggg
     7981 ttgccgttga ctttggtttg gttttatttt cacaaccctc tggtcagtta gttatgcagc
     8041 aggtccagct ggctactcgg cccagtggca tccactggtc tggctccctc agttgcccac
     8101 gcaggatgct tctgggtctc tgacgtggag ctgcacagat gagctgccca cgtctgctca
     8161 catccccaag gatgcttaag atctaggagg tataccacag gaggggagag gggagcaccg
     8221 tggtgtcctg tgaatgcagg tggtctgtgg agtcctgtcg cctttcacag ctgctgtgca
     8281 ggattctctt tgagagctgt cacacacagc ggagcaaggg ctgaagtttt cacgagaaca
     8341 caagcgctct gactgcacac ctggggacag ttagctttgg aatcgttaga actgtcaaga
     8401 tttcctgtca gcatcatgag atctcatccc atcactttcc taaggattct ctgcaatcaa
     8461 aaatacaggt agcaatttgg gttcaaaatt tttaactagt acacagacaa cctgtggaaa
     8521 caattttttt ttttgtaaat aaattttatt ataaagacct cgcaaacctc ttcggaagac
     8581 attcttactc cagatgcagg caaaaacact tcaaggtttg taaatgacta tttcctgaca
     8641 taaagccttt ttttttttat taaaatgcaa aacgttcttc agaataaact ctgtataatg
     8701 tcatcatatg gggagctctc ctcacacagc tggctctact gggggagctt cgggcggctt
     8761 tttccgccct tggtctccga gaccgatagt aacttcacac cagctgcaga gtgctgttct
     8821 cctaaagggc taaactacca tcagcattta ccttggactc tgtcgtgctg ggtgtctgtc
     8881 tgtctgtctg actgtgcgac gtaacatcag cagatcacac tcacgtgtgt tctggaatgg
     8941 gtgatcgttc ccaaagtcag ctgtcaacgc tgcctggcgt ttcaggctgt ccttcccggt
     9001 atgtctgctt taagcctggt tcaacctctc atttaatatt aaatttctct ttgtaagaaa
     9061 aaaaaaaaaa aaaaa
//
