LOCUS       NM_001418448            1437 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus calcium binding protein 5 (Cabp5), transcript variant
            3, mRNA.
ACCESSION   NM_001418448
VERSION     NM_001418448.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1437)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1437)
  AUTHORS   Park,K.U., Randazzo,G., Jones,K.L. and Brzezinski,J.A. 4th.
  TITLE     Gsg1, Trnp1, and Tmem215 Mark Subpopulations of Bipolar
            Interneurons in the Mouse Retina
  JOURNAL   Invest Ophthalmol Vis Sci 58 (2), 1137-1150 (2017)
   PUBMED   28199486
REFERENCE   3  (bases 1 to 1437)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1437)
  AUTHORS   Star,E.N., Zhu,M., Shi,Z., Liu,H., Pashmforoush,M., Sauve,Y.,
            Bruneau,B.G. and Chow,R.L.
  TITLE     Regulation of retinal interneuron subtype identity by the Iroquois
            homeobox gene Irx6
  JOURNAL   Development 139 (24), 4644-4655 (2012)
   PUBMED   23172916
REFERENCE   5  (bases 1 to 1437)
  AUTHORS   Sokal,I. and Haeseleer,F.
  TITLE     Insight into the role of Ca2+-binding protein 5 in vesicle
            exocytosis
  JOURNAL   Invest Ophthalmol Vis Sci 52 (12), 9131-9141 (2011)
   PUBMED   22039235
  REMARK    GeneRIF: This study shows that CaBP5 interacts with Munc18-1 and
            myosin VI, two proteins involved in the synaptic vesicle cycle
            stimulating neurite outgrowth and vesicle exocytosis
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1437)
  AUTHORS   Rieke,F., Lee,A. and Haeseleer,F.
  TITLE     Characterization of Ca2+-binding protein 5 knockout mouse retina
  JOURNAL   Invest Ophthalmol Vis Sci 49 (11), 5126-5135 (2008)
   PUBMED   18586882
REFERENCE   7  (bases 1 to 1437)
  AUTHORS   Cheng,C.W., Chow,R.L., Lebel,M., Sakuma,R., Cheung,H.O.,
            Thanabalasingham,V., Zhang,X., Bruneau,B.G., Birch,D.G., Hui,C.C.,
            McInnes,R.R. and Cheng,S.H.
  TITLE     The Iroquois homeobox gene, Irx5, is required for retinal cone
            bipolar cell development
  JOURNAL   Dev Biol 287 (1), 48-60 (2005)
   PUBMED   16182275
REFERENCE   8  (bases 1 to 1437)
  AUTHORS   Bramblett,D.E., Pennesi,M.E., Wu,S.M. and Tsai,M.J.
  TITLE     The transcription factor Bhlhb4 is required for rod bipolar cell
            maturation
  JOURNAL   Neuron 43 (6), 779-793 (2004)
   PUBMED   15363390
REFERENCE   9  (bases 1 to 1437)
  AUTHORS   Sokal,I., Li,N., Verlinde,C.L., Haeseleer,F., Baehr,W. and
            Palczewski,K.
  TITLE     Ca(2+)-binding proteins in the retina: from discovery to etiology
            of human disease(1)
  JOURNAL   Biochim Biophys Acta 1498 (2-3), 233-251 (2000)
   PUBMED   11108966
REFERENCE   10 (bases 1 to 1437)
  AUTHORS   Haeseleer,F., Sokal,I., Verlinde,C.L., Erdjument-Bromage,H.,
            Tempst,P., Pronin,A.N., Benovic,J.L., Fariss,R.N. and Palczewski,K.
  TITLE     Five members of a novel Ca(2+)-binding protein (CABP) subfamily
            with similarity to calmodulin
  JOURNAL   J Biol Chem 275 (2), 1247-1260 (2000)
   PUBMED   10625670
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC156985.12.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784649.740293.1,
                                           SRR17784648.222309.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849385,
                                           SAMN01164131 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-252               AC156985.12        139851-140102       c
            253-283             AC156985.12        137486-137516       c
            284-427             AC156985.12        136847-136990       c
            428-537             AC156985.12        134804-134913       c
            538-1437            AC156985.12        131922-132821       c
FEATURES             Location/Qualifiers
     source          1..1437
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 7.87 cM"
     gene            1..1437
                     /gene="Cabp5"
                     /note="calcium binding protein 5"
                     /db_xref="GeneID:29865"
                     /db_xref="MGI:MGI:1352746"
     exon            1..252
                     /gene="Cabp5"
                     /inference="alignment:Splign:2.1.0"
     CDS             190..726
                     /gene="Cabp5"
                     /note="isoform 3 is encoded by transcript variant 3"
                     /codon_start=1
                     /product="calcium-binding protein 5 isoform 3"
                     /protein_id="NP_001405377.1"
                     /db_xref="GeneID:29865"
                     /db_xref="MGI:MGI:1352746"
                     /translation="MQFPMGPACIFLRKGIAEKQRERPLGQDELDELREAFLEFDKDQ
                     DGFISYKDLGNLMRTMGYMPTEMELTELGQQIRMNLGGRVDFEDFVELMTPKLLAETA
                     GMIGVQEMRDAFKEFDANGDGEITLAELQQAMQRLLGEKLTPREIAEVVQEADINGDG
                     TVDFEGNTLGKKSRNLHL"
     exon            253..283
                     /gene="Cabp5"
                     /inference="alignment:Splign:2.1.0"
     exon            284..427
                     /gene="Cabp5"
                     /inference="alignment:Splign:2.1.0"
     exon            428..537
                     /gene="Cabp5"
                     /inference="alignment:Splign:2.1.0"
     exon            538..1437
                     /gene="Cabp5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctccactgt ctaagtagaa ttttccatga gctgtcacag atctctcaca gggactgagg
       61 aagaagctaa gagaaacagg aggagttggc aaaggattga gacaatcagg aagctgggtt
      121 gcctgctgca aggaagtagg aaggaggggc catcttgaca tcagagcttg gtgaacacta
      181 cctgctccaa tgcagtttcc aatgggtcct gcctgcatct tcttgagaaa aggcattgct
      241 gaaaagcagc gggagagacc actgggacag gatgagcttg atgagctccg ggaagcattt
      301 cttgaatttg acaaggacca agatgggttc atctcttaca aggatttggg caatctcatg
      361 agaacgatgg gttacatgcc tacagagatg gagttgactg agttgggcca gcaaatccga
      421 atgaaccttg gtggccgtgt agactttgaa gactttgtgg aactgatgac ccccaaattg
      481 cttgcagaga cagcagggat gattggtgtc caggagatgc gagatgcctt caaggagttt
      541 gatgccaatg gagatgggga gatcacactg gcagaactgc agcaggccat gcagaggctg
      601 ctgggggaga agctcacacc ccgggagatt gctgaggtgg tacaggaggc tgatatcaat
      661 ggagatggca ctgttgactt tgaaggtaat actttgggga agaaatccag gaatctacac
      721 ctgtgacttc tctatgtggt tctccctcca gttcatctac tctataatct tctccaagtc
      781 ctcatttgaa ggtgtgttct catttcatgt gtgttgctgt gataaagcag ctcactcact
      841 ggtctttgct cagctagctt tctcatgtag cccagaacca cttgtccagg gaatggtgct
      901 gcccagagta gactggggac tcctgtacca attagaaatg aaacatagac ccacagatat
      961 gcccacaggc taatctgatt ctggtagttc ttcacgtgag gtttcccctt tccagacaac
     1021 tcttggttgt gtcaagttga cagtaactat gaactagtac tctgtgggat cacatttgag
     1081 ggaggcaaat ttaaacttgg ctatatcaag tttatattgt gatattctct gaattaaggt
     1141 actcagcatc tagttattgc cttcaggttg ggtcaaaatc tatagtctat ttttcaatcc
     1201 atgcctattt agcctaccca gtcttatctt ttgcaaccat gatgtgaatt ggtgtgcttt
     1261 ggggaacatg tttcctattc tgcatccttc aacttctctt ccctgtaacc tatgtcctgc
     1321 cctcttgttc acttataata cttataaatc cttcaaggaa acaagccaac aacacccctt
     1381 tgtcaagaat ctcccctctc ccttgtctga ataaattaag cctgactgtg aacttta
//
