LOCUS       NM_001310712            1635 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus calcium binding protein 1 (Cabp1), transcript variant
            1, mRNA.
ACCESSION   NM_001310712 XM_006530374
VERSION     NM_001310712.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1635)
  AUTHORS   Lopez,J.A., Romero,L.O., Kaung,W.L., Maddox,J.W., Vasquez,V. and
            Lee,A.
  TITLE     Caldendrin Is a Repressor of PIEZO2 Channels and Touch Sensation in
            Mice
  JOURNAL   J Neurosci 44 (10), e1402232023 (2024)
   PUBMED   38262725
  REMARK    GeneRIF: Caldendrin Is a Repressor of PIEZO2 Channels and Touch
            Sensation in Mice.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1635)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 1635)
  AUTHORS   Xiao,Z., Liu,S., Li,Z., Cui,J., Wang,H., Wang,Z., Ren,Q., Xia,L.,
            Wang,Z. and Li,Y.
  TITLE     The Maternal Microbiome Programs the m6A Epitranscriptome of the
            Mouse Fetal Brain and Intestine
  JOURNAL   Front Cell Dev Biol 10, 882994 (2022)
   PUBMED   35874829
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1635)
  AUTHORS   Konietzny,A., Grendel,J., Kadek,A., Bucher,M., Han,Y., Hertrich,N.,
            Dekkers,D.H.W., Demmers,J.A.A., Grunewald,K., Uetrecht,C. and
            Mikhaylova,M.
  TITLE     Caldendrin and myosin V regulate synaptic spine apparatus
            localization via ER stabilization in dendritic spines
  JOURNAL   EMBO J 41 (4), e106523 (2022)
   PUBMED   34935159
  REMARK    GeneRIF: Caldendrin and myosin V regulate synaptic spine apparatus
            localization via ER stabilization in dendritic spines.
REFERENCE   5  (bases 1 to 1635)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1635)
  AUTHORS   Schilling,K. and Oberdick,J.
  TITLE     The treasury of the commons: making use of public gene expression
            resources to better characterize the molecular diversity of
            inhibitory interneurons in the cerebellar cortex
  JOURNAL   Cerebellum 8 (4), 477-489 (2009)
   PUBMED   19554387
REFERENCE   7  (bases 1 to 1635)
  AUTHORS   Cui,G., Meyer,A.C., Calin-Jageman,I., Neef,J., Haeseleer,F.,
            Moser,T. and Lee,A.
  TITLE     Ca2+-binding proteins tune Ca2+-feedback to Cav1.3 channels in
            mouse auditory hair cells
  JOURNAL   J Physiol 585 (Pt 3), 791-803 (2007)
   PUBMED   17947313
  REMARK    GeneRIF: our results implicate CaBP1 rather than CaBP4 in
            conferring the anomalous slow inactivation of Ca(v)1.3 Ca(2+)
            currents required for auditory transmission
REFERENCE   8  (bases 1 to 1635)
  AUTHORS   Bramblett,D.E., Pennesi,M.E., Wu,S.M. and Tsai,M.J.
  TITLE     The transcription factor Bhlhb4 is required for rod bipolar cell
            maturation
  JOURNAL   Neuron 43 (6), 779-793 (2004)
   PUBMED   15363390
REFERENCE   9  (bases 1 to 1635)
  AUTHORS   Gregory,M.S., Duffner,L.A., Hahn,E.L., Tai,H.H., Faunce,D.E. and
            Kovacs,E.J.
  TITLE     Differential production of prostaglandin E(2) in male and female
            mice subjected to thermal injury contributes to the gender
            difference in immune function: possible role for
            15-hydroxyprostaglandin dehydrogenase
  JOURNAL   Cell Immunol 205 (2), 94-102 (2000)
   PUBMED   11104581
REFERENCE   10 (bases 1 to 1635)
  AUTHORS   Haeseleer,F., Sokal,I., Verlinde,C.L., Erdjument-Bromage,H.,
            Tempst,P., Pronin,A.N., Benovic,J.L., Fariss,R.N. and Palczewski,K.
  TITLE     Five members of a novel Ca(2+)-binding protein (CABP) subfamily
            with similarity to calmodulin
  JOURNAL   J Biol Chem 275 (2), 1247-1260 (2000)
   PUBMED   10625670
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            KJ364651.1 and AI851121.1.
            
            On Jul 18, 2015 this sequence version replaced XM_006530374.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KJ364651.1, CX240152.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1458              KJ364651.1         1-1458
            1459-1635           AI851121.1         1-177               c
FEATURES             Location/Qualifiers
     source          1..1635
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 55.99 cM"
     gene            1..1635
                     /gene="Cabp1"
                     /gene_synonym="caldendrin"
                     /note="calcium binding protein 1"
                     /db_xref="GeneID:29867"
                     /db_xref="MGI:MGI:1352750"
     exon            1..728
                     /gene="Cabp1"
                     /gene_synonym="caldendrin"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..1187
                     /gene="Cabp1"
                     /gene_synonym="caldendrin"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="calcium-binding protein 1 isoform 1"
                     /protein_id="NP_001297641.1"
                     /db_xref="CCDS:CCDS80379.1"
                     /db_xref="GeneID:29867"
                     /db_xref="MGI:MGI:1352750"
                     /translation="MGGGDGAAFKRPGDGARLQRVLGLGSRRAPRSLPSGGPAPPPPG
                     HASAGPAAMSSHIAKSESKTSLLKAAAASGGSRAPRHSSARDPGLRGRRLPGPCPGSP
                     PPCGDPSSRRPLCRPVPRDEGARGSRRGLPQAHCRPRETLPPARGRDGEERGLAPALG
                     LRGSLRSRGRGDPAPAGTPEADPFLHRLRPMLSSAFGQDRSLRPEEIEELREAFREFD
                     KDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELMGPKLLA
                     ETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLN
                     GDGRVDFEEFVRMMSR"
     exon            729..759
                     /gene="Cabp1"
                     /gene_synonym="caldendrin"
                     /inference="alignment:Splign:2.1.0"
     exon            760..903
                     /gene="Cabp1"
                     /gene_synonym="caldendrin"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1013
                     /gene="Cabp1"
                     /gene_synonym="caldendrin"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1161
                     /gene="Cabp1"
                     /gene_synonym="caldendrin"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1619
                     /gene="Cabp1"
                     /gene_synonym="caldendrin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1597..1602
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cabp1"
                     /gene_synonym="caldendrin"
                     /note="hexamer: AATAAA"
     polyA_site      1619
                     /gene="Cabp1"
                     /gene_synonym="caldendrin"
                     /note="major polyA site"
ORIGIN      
        1 gggcggggcg cggcggcacc tgggccgcgg gagagccggg ggtgggctct cgggggacaa
       61 ccagctgccc ccccagatct gcagcgccgg ccgccgggag ctcgaggctc caggcgcaga
      121 ggctgcgctg tcacatgggc ggcggcgacg gggccgcatt taagcggcca ggggacggcg
      181 cccgcctgca gcgcgtcctc gggcttggct cccgccgggc gccccgctct ctgccctccg
      241 ggggccccgc accacccccg ccgggccatg cgagcgcggg ccccgccgcg atgagctcgc
      301 acattgccaa gagcgagtcc aagacgtcgc tgctcaaggc ggcggcggcg agcgggggca
      361 gccgggctcc ccgccacagc tctgcgcggg accccgggct gcgtggccgc cggctgcccg
      421 gtccctgccc cggctcgcct ccaccgtgcg gggaccccag ctcgcggagg cccctgtgcc
      481 ggcccgtgcc gcgggacgag ggcgcgcgcg ggagccggcg tgggctgccc caggcgcact
      541 gcaggccccg ggagacgcta ccgccggccc gcgggcgcga tggggaggaa cgggggctgg
      601 cgccagcgct cggtctacgg ggctccctgc gatcgcgggg tcgcggggac ccggctcctg
      661 ctggcacccc cgaggcggac ccgttcctcc accggctgcg ccccatgctc agctccgcct
      721 tcggccagga cagatcgtta cgaccagagg agattgaaga gctccgagag gccttccgag
      781 aatttgacaa agacaaggat ggttacatca actgccggga cctggggaac tgcatgcgca
      841 ccatgggcta catgcccacc gagatggagc tcattgagct gtctcagcag atcaacatga
      901 acctgggtgg ccacgtggat tttgatgact ttgtggaact gatgggccct aaactcctgg
      961 cggagacggc agatatgatt ggtgtaaagg agctgagaga cgcctttcgg gagtttgata
     1021 ccaacggtga cggggagata agtacgagcg agcttcgaga ggccatgagg aagctcctgg
     1081 gtcatcaggt gggacaccgg gacatagagg aaattatccg agacgtggac ctcaatggag
     1141 atggacgagt ggactttgaa gagtttgtcc ggatgatgtc tcgctgaggc ccccgagggg
     1201 ctcctccagg tctgccaact cccacaggcg gggagaagag ctgagctcgc ctcacccccg
     1261 cagtagctgc cgaaagccca ggatgtactg gcggatgggg cctgcctgca ccctggggag
     1321 gtgcccaccc cggacccccc cacccctccg cactgtgaaa gactcacaac tcttgcaact
     1381 ggaaaaaggg ggcgcccgcc ggcgaggagg ccacagtgcc aagccggtag aggacatgca
     1441 aggcaccaag tgccatgtgc ccagccgctg ctggctggct gggtgggcca gggagccggc
     1501 cagcagaccc cacacagcat gtgtgcccca gggcagagcc tctcagcgcc ttcctgatgc
     1561 ccgtcccagc tcgcctagcc ctttgatctc agaaccaata aaaaaaaaac cgagaatgaa
     1621 aaaaaaaaaa aaaaa
//
