LOCUS       NM_028491               1238 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ciliary associated calcium binding coiled-coil 1
            (Cabcoco1), mRNA.
ACCESSION   NM_028491 XM_979581
VERSION     NM_028491.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1238)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1238)
  AUTHORS   Wang,M., Kang,J., Shen,Z., Hu,Y., Chen,M., Cui,X., Liu,H. and
            Gao,F.
  TITLE     CCDC189 affects sperm flagellum formation by interacting with
            CABCOCO1
  JOURNAL   Natl Sci Rev 10 (9), nwad181 (2023)
   PUBMED   37601242
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1238)
  AUTHORS   Kawashima,A., Kigoshi,T., Katoh,Y., Ishikawa,Y., Shawki,H.H.,
            Inoue,N., Tamba,M., Matsuda,M. and Okamura,N.
  TITLE     CABCOCO1, a novel coiled-coil protein With calcium-binding
            activity, is localized in the sperm flagellum
  JOURNAL   Mol Reprod Dev 83 (10), 912-926 (2016)
   PUBMED   26990073
  REMARK    GeneRIF: These results suggested that CABCOCO1 is involved in the
            control of sperm flagellar movement.
REFERENCE   4  (bases 1 to 1238)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 1238)
  AUTHORS   McClintock,T.S., Glasser,C.E., Bose,S.C. and Bergman,D.A.
  TITLE     Tissue expression patterns identify mouse cilia genes
  JOURNAL   Physiol Genomics 32 (2), 198-206 (2008)
   PUBMED   17971504
  REMARK    GeneRIF: 1700040L02Rik is most abundantly expressed in tissues rich
            in highly ciliated cells, such as olfactory sensory neurons, and is
            predicted to be important to cilia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK029622.1.
            
            On May 4, 2006 this sequence version replaced XM_979581.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029622.1, AK006661.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1238
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 35.4 cM"
     gene            1..1238
                     /gene="Cabcoco1"
                     /gene_synonym="1700040L02Rik"
                     /note="ciliary associated calcium binding coiled-coil 1"
                     /db_xref="GeneID:73287"
                     /db_xref="MGI:MGI:1920537"
     exon            1..129
                     /gene="Cabcoco1"
                     /gene_synonym="1700040L02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..945
                     /gene="Cabcoco1"
                     /gene_synonym="1700040L02Rik"
                     /note="uncharacterized protein C10orf107 homolog"
                     /codon_start=1
                     /product="ciliary-associated calcium-binding coiled-coil
                     protein 1"
                     /protein_id="NP_082767.1"
                     /db_xref="CCDS:CCDS23905.1"
                     /db_xref="GeneID:73287"
                     /db_xref="MGI:MGI:1920537"
                     /translation="MKAASSKENVSGSSTGLTSWALTTPGVSPVGSTSDSEENERILS
                     PDILSSDQIIDLLGEENENGIQEKLGVFLNFKNLQTCLRDAILLDYYVSGFCWAKEMN
                     FSIEQYSKFMTLLDMLLHNLQTLHMSLEDSIKWLGEVMAEIGPNHSQKSEDFHVFEVK
                     EANAIIDYLKISLFQHYRLYEFLFYSTREEIVIGTEQTIEVVKPADYPFPAPLEEGIS
                     LDTYSTFIEPLPTPDMEQKVLDQEQGTQEALLESEMREEDPLGGFTIDDVKSALERVT
                     DEVLISMQKEISEKLQVQEEAFNARIEKLKKA"
     exon            130..218
                     /gene="Cabcoco1"
                     /gene_synonym="1700040L02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            219..388
                     /gene="Cabcoco1"
                     /gene_synonym="1700040L02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            389..533
                     /gene="Cabcoco1"
                     /gene_synonym="1700040L02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            534..606
                     /gene="Cabcoco1"
                     /gene_synonym="1700040L02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            607..729
                     /gene="Cabcoco1"
                     /gene_synonym="1700040L02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            730..870
                     /gene="Cabcoco1"
                     /gene_synonym="1700040L02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            871..1238
                     /gene="Cabcoco1"
                     /gene_synonym="1700040L02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1216..1221
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cabcoco1"
                     /gene_synonym="1700040L02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1235
                     /gene="Cabcoco1"
                     /gene_synonym="1700040L02Rik"
ORIGIN      
        1 accacggttg ccttggcgat gaaggctgct tcctctaaag aaaacgtgtc agggtcgtcc
       61 acaggattga cctcctgggc gttgaccacc cctggggtgt cgccagtagg cagcacttct
      121 gactctgagg agaatgaaag gattctgtct ccagatatac tctcctctga ccagatcatt
      181 gacctgttgg gagaagagaa cgaaaatgga attcaagaaa aactgggagt gtttctgaat
      241 tttaaaaatc tccagacttg cctgcgtgac gccatcctct tggactacta tgtgtctggc
      301 ttctgttggg ccaaggagat gaacttttct attgagcagt attccaagtt tatgaccttg
      361 ctggacatgc tacttcataa tcttcaaaca ctgcacatgt ccttagagga cagcattaag
      421 tggctcgggg aagtgatggc agaaatcgga ccaaaccact cgcagaagag tgaagatttc
      481 catgtcttcg aagtcaagga agccaacgcc atcatcgatt acttaaaaat cagcttattc
      541 cagcactaca ggctctacga gtttctgttc tactccacca gggaagaaat tgtcatcggg
      601 actgagcaaa ccatagaggt tgtcaagcct gcagactacc ccttcccagc ccccctggaa
      661 gaaggtatct cattggacac gtattcaacc ttcatagagc cattgccaac gccggacatg
      721 gaacagaagg tgctggatca agagcaaggg actcaggaag ccctgctgga gagtgaaatg
      781 agagaggagg atcccttagg tggcttcacc attgatgacg taaaatcagc cctggagcga
      841 gtgacggatg aggttttgat tagcatgcag aaagagataa gtgaaaaact ccaagtacag
      901 gaagaggcct ttaacgcacg aatagagaaa ctgaagaaag cctgaagacg cggtacaagc
      961 aaagtgatgc tcaacttcag agaaacaaac aaaaccggcc agtacaatag tgtctctaga
     1021 gcgctgggtc acttccatgc agtccgagaa aggaaaaccc acttccggtt atccggactg
     1081 actggcagca cgttgtcccg cccctcccat cccacaccca cctctgagtt tatagtgtaa
     1141 gagcattgct ttgtgtgtat aatcttggag agttatatac gaaaatacaa ttactattag
     1201 gatgctgttt tgactaataa atacaattca tcttccac
//
