LOCUS       NM_198614               6764 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus C2 calcium-dependent domain containing 4C (C2cd4c),
            transcript variant 1, mRNA.
ACCESSION   NM_198614 XM_137193
VERSION     NM_198614.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6764)
  AUTHORS   Omori,H., Ogaki,S., Sakano,D., Sato,M., Umeda,K., Takeda,N.,
            Nakagata,N. and Kume,S.
  TITLE     Changes in expression of C2cd4c in pancreatic endocrine cells
            during pancreatic development
  JOURNAL   FEBS Lett 590 (16), 2584-2593 (2016)
   PUBMED   27349930
  REMARK    GeneRIF: our results suggest that C2cd4c is dispensable for
            pancreatic development.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY268666.1 and BC089008.1.
            
            On Dec 12, 2009 this sequence version replaced NM_198614.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 both encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089008.1, CF539082.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-256               BY268666.1         2-257
            257-1839            BC089008.1         239-1821
            1840-6764           BC089008.1         1823-6747
FEATURES             Location/Qualifiers
     source          1..6764
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..6764
                     /gene="C2cd4c"
                     /gene_synonym="4932409I22Rik; Fam148c; Gm238"
                     /note="C2 calcium-dependent domain containing 4C"
                     /db_xref="GeneID:237397"
                     /db_xref="MGI:MGI:2685084"
     exon            1..262
                     /gene="C2cd4c"
                     /gene_synonym="4932409I22Rik; Fam148c; Gm238"
                     /inference="alignment:Splign:2.1.0"
     exon            263..6747
                     /gene="C2cd4c"
                     /gene_synonym="4932409I22Rik; Fam148c; Gm238"
                     /inference="alignment:Splign:2.1.0"
     CDS             290..1549
                     /gene="C2cd4c"
                     /gene_synonym="4932409I22Rik; Fam148c; Gm238"
                     /note="nuclear-localized factor 3; C2cd4cC2CD4 family;
                     family with sequence similarity 148, member C"
                     /codon_start=1
                     /product="C2 calcium-dependent domain-containing protein
                     4C"
                     /protein_id="NP_941016.2"
                     /db_xref="CCDS:CCDS23979.1"
                     /db_xref="GeneID:237397"
                     /db_xref="MGI:MGI:2685084"
                     /translation="MRKTNMWFLERLRGSGENGASRGEAGDKSSKGPLYSNVLTPDKI
                     PDFFIPPKLPSGPTEAEGQADLGPSTSEQNLASPGPRRAPRSPRLPAKLASESRSLLK
                     AATRHVIQIESAEDWTAEEATNADPQAQGAMSLPSVPKAQTSYGFATLAESPHTRRKE
                     SLFHSEHGALAQVGSPGAGRRRAGAKGNGGDGGSREVGGALMSPSRYFSGGESDTGSS
                     AESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLKQSVGRHGSLSADDSTPDTSPGVRRR
                     LSRRATPEPGPESGQAPRGEHTVKMGTRGSVRLLAEYEAAQARLRVRLLAAEGLYDRP
                     CDARSINCCVGLCLVPGKLQKQRSTIIKNSRHPIFNEDFFFDGLGPASVRKLALRIKV
                     VNKGSSLKRDTLLGEEELPLTSLLPFL"
     regulatory      2867..2872
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C2cd4c"
                     /gene_synonym="4932409I22Rik; Fam148c; Gm238"
                     /note="hexamer: AGTAAA"
     polyA_site      2887
                     /gene="C2cd4c"
                     /gene_synonym="4932409I22Rik; Fam148c; Gm238"
                     /note="major polyA site"
     regulatory      6723..6728
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C2cd4c"
                     /gene_synonym="4932409I22Rik; Fam148c; Gm238"
                     /note="hexamer: AATAAA"
     polyA_site      6747
                     /gene="C2cd4c"
                     /gene_synonym="4932409I22Rik; Fam148c; Gm238"
ORIGIN      
        1 ggaatacggc ttggtgggcg gtttcccgcg ccgagaggag agctggccac tgcgctaccg
       61 cctcgctcgc agctgcgccg ggctgtagcc tagctccgcg ttccggagtc gccgcagccc
      121 gtggggcagg tgagcccagc gcgctccgcg ctacccatac ccggcgcaca gggagtcggg
      181 ggcgcggtca gttcgctgca ccgggcccag ggctgtcgcc gcctccccca acgcacagcg
      241 cagcagctga gtgaagccac agactcctgg tctcttgcct gtcgccctca tgagaaaaac
      301 caacatgtgg ttcttggaac gacttcgggg gtctggggag aacggagcca gccgcggtga
      361 ggctggggac aagtcttcca agggtccctt gtatagcaac gtgctgactc cggacaagat
      421 ccccgacttc ttcatcccgc ccaagctgcc ctctggcccc acagaggctg agggacaggc
      481 ggacctgggc ccctccacct cagagcaaaa cctggcttca cctgggcccc gtcgagcacc
      541 tcgcagtccc cggctgccgg ccaagttggc ctcagagagc aggagcctgc tgaaggcagc
      601 cacacgacat gtgattcaga tagagagtgc ggaggactgg acagccgagg aagccaccaa
      661 cgctgacccc caggcgcagg gtgccatgtc attgccctct gtgcccaagg ctcagacatc
      721 ctatggcttt gccacactgg ccgagagccc ccacaccagg cgcaaggagt cccttttcca
      781 cagtgagcac ggggccctgg cccaggtcgg atcccctggt gctggccgcc ggcgagcagg
      841 ggccaagggc aatggaggtg atgggggatc ccgggaggtt gggggggccc tgatgagccc
      901 tagccgctac ttcagtggcg gggaaagtga cacagggtcc tctgctgagt cgtccccctt
      961 cgggtcccct ctgctgtctc gctctgtatc gctgctcaag ggcttcgccc aggacagcca
     1021 ggccaaagtg agccagctga aacagtcggt aggtcgccat ggctccctgt ctgcggatga
     1081 tagcacacca gacaccagcc caggtgtccg tcgccgcttg tcccgcaggg ctaccccgga
     1141 gccaggcccg gagtctggcc aggcaccacg tggagagcac acagtgaaga tgggcaccag
     1201 gggcagcgtg aggctgctgg ccgagtacga ggctgctcag gcccgcctgc gtgtgcgcct
     1261 gctggcggcc gagggcctgt atgaccggcc ctgtgatgcc cggagcatca attgctgcgt
     1321 ggggctgtgc ctggtgcccg ggaagctgca gaagcagcgg agcaccatca tcaaaaacag
     1381 ccgccacccc atcttcaacg aggacttctt ctttgatggc ctggggccag ccagtgtgcg
     1441 taagctggcc ctcaggatca aggtggtcaa taagggtagc agcctcaagc gggacacact
     1501 cctgggggag gaggaattgc cactgacctc cctgttgccc tttctgtgag gtcattggtt
     1561 cctcccttct atacttagct cagctgagcc gggtgagggt gggcggggcc tcttgccccg
     1621 ctttccctgg gtctcttagt ggagtgcgct taggagatgg gctgctgggg caaatattgc
     1681 tgactggaac cccttccccc tccaccttgg cccatccaca tagagttgtg gggttcgtag
     1741 cagtcccagg atcctggtac ctaaggcagc tgggacccag aacagagttt cctgagtgtg
     1801 gaacttgtcc cccgcccccc gccccccccc cccccccccg cttggctgca cgcgggtgtt
     1861 tttcccgcac ggcccggttg ctcagatgct ccgataactt ctttgagact tcccccagtc
     1921 tgtgggaagt catcctccct ggccaggctg gctccaggta ggcctaacct cccaagttct
     1981 ggcgctgatg tgccatctag agctacagga gggcttggct gcgggaatca agaaagccag
     2041 agtgcacaga gagccgaagg aggcggtgac tcttggctga tggctctttg gcacaggctt
     2101 ccctccactc ctgctgatca accagagcca cctgtaaccc aggagcttct gcctcaagtc
     2161 tgtggctcta tcctcatctt gcaagctaca aaccactttc ccagggtgcc cttggcaagt
     2221 cgccctttgc tccagaatgt aaataggcta tagctgtggt gggtgggctg tgtgtatgtg
     2281 tgtgtgtgtg tgtgtgtgta tgtgtgcccg tgtgcacgca cttgtgttgg ggggcagggt
     2341 tctaggttgt ttatgtgtgt gtctttcctg cacaggaaat cctcatgggg tgggatacat
     2401 gggtccctga atggctgctg tgttttgcac aaactctaag actcagaaca gaatggaccg
     2461 cctgttggat aatggcagat aagggagggt ccagcattcc tttgtctttt gctgtttcct
     2521 taaactccca aagcccttgt ccctctagaa aagggttttg agattgattg cttggacctt
     2581 tgaggtgagc caagcaccta ggagttgaac ccctacccaa cccctgtgcc tggtccccat
     2641 tgtctctggg actagggtac atccaggacc tgggctggtc agttggagtg gtggacagag
     2701 ggccccaggg gtctcttgct tttttctgtc tcccatcttc tatgctctgt ggggccctgt
     2761 tttttatacc ctgcactgtt tgatatctct gtttgcagtt gactgtacgt gaatctttta
     2821 agacgcctcc cccaaatgtg tttgtttata atgctgtttt gagtgcagta aaggtgtttg
     2881 gggagtgcgg gggtgcaggc ctgcttgatt tgtgtttaat aacaacagga gtttaaccgt
     2941 ggctgctggc aaggtggggg agcctgaggt gaggaaggcc tttctcacac tcctactctc
     3001 tactgcttgg ggttgaacag aagaagatag aaaagggagg gagaccctgg ccgttgtgaa
     3061 gagggctcac aggtcccacg gctgggctct gtcctcagtc tctatccaca caactcagcc
     3121 tgtccctaca acagcccgca gagtggacat tgtggatatc ccatgaagcg ctggaggcct
     3181 gtggactctg tccagctatc tggtagaggt tgggagggga gacaagttgt gcaggcccca
     3241 gagagatatc tccatcttct ttctaggttt tgtcaacctg gtctcttcag gcactgctgg
     3301 ttgcctaaac caggtactgg cctggagctg tctggcccag ggagaccgga agacaggtct
     3361 agaggctgct gcctagatgg ctgatgcctc tagggcttct cagctagaac agggttttct
     3421 ctgcagtgag tcactgtgta gggatgatct gacactggag ttggagcatc tggcccctgg
     3481 gagtcaccgt tcctatgcac ataccttcag cacacccagg gtgctgggtg aggatgtctt
     3541 agatggatgg caggccccgc tgagaggcag aaggccccgc tgcccctcat taccttgggg
     3601 ctactctgtc aacgtgggtg ggttggacct atgctaaggg gaagacctgc tgtactatga
     3661 cacctgtggc cttctgccag cctgggcatg ggtaacagca atggagagaa gaaattggga
     3721 cgtccaagac aatgtgggaa gggctgggct ggccatgccc gtggctacgg gagagaagtg
     3781 agtagaaccc aggctgggtg ccctggtgac tggaggggca ggttcaagga tatggactga
     3841 cacgtctcct agacttctgg gacagagcac agctcctgct gtctacccaa ggtcctgcga
     3901 cccctctgat cccctccaag gaccccatgt ccctctgact ccaggacagg actctgtgtc
     3961 cctctctgcc caggactggt cagtttagct tagtgcccca gggtacatca aatgcccatg
     4021 ttgccactgg gatccccctg ctacttccgg atccctagca gcccttcctg ccagtagcca
     4081 gcatcactga ggctgaggtc ctaggacggg ttgccagggc aactggcctt ctcctgggcc
     4141 acattcatgc cattcaagag ctgatgtcat ctctggaaac aagtgttctg tgtgtcatcc
     4201 tgacaccctg tgtggctctg aacacatccc tgccttggtt tgtacacttt gtgtgtgttg
     4261 acccgttgtc catatgtaat gtgtgtgtgg ccttttatgg ccatgtttta ccctgtgtct
     4321 ctgtgtctga ctgtggcttc cctgggccaa agcacagggc ctgcatcgtg atttccaata
     4381 tcattgctgc ccgaagctga gagccccttt gagcttggtc cccactctgc ctcatactgc
     4441 ctgggagtac acctgaagaa gcacacagcg tgtccggcat tgcctgttga catgagtccc
     4501 aggagaactt ctctctgcct tgcaacagcc aggggactca ggctgcaagg tctgtggaga
     4561 tggcagaggc aggcatgagt atcagcatgc accctgcctg catggcttct gtctgagctg
     4621 tctttccttg aagatgcagt gggcagccag gtgctcaccg gcagaagcct cttagtggat
     4681 tccactcgct gctggtgtgc catcctcaga gggaactagt ggaagggatg ctgagctgag
     4741 ggagagggtt ccatccatgt tggttgcctg ggtccagcag gcgctctccc tggctgggtg
     4801 tcctttcagc ctggaaaggt gacagagtct gctctgtgct ctagcctgat ggcttccaac
     4861 aagaatgttg gggcagtaag cctatggctg agggacaggg gtcctgggat gctccagggc
     4921 gaagcacaaa agggacacag ctccagaagc ctgggcagtg gacacttgca aagcacgagc
     4981 ctcctgcctc agatctgtag aaggcactga atctaggaag gcaacagagg aaaggggtcc
     5041 agagtggggg ggccaaggaa gggagtggag ggggtggggc aacagggatg acctactcac
     5101 gccctgtata cccttgctgg ccctactctg cagccatcca cgagctctgg agctccacca
     5161 gccctcccta agcccactca ctgatgtggg gtactgaggc tgtttgaggg gcctccctta
     5221 tctccatgtc ccagatcaag tctctgtttt ccacttgact gtgtgggggt tccaggtgag
     5281 cacatgatca gcttgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtag taaccctggg
     5341 ctcagtcctc atgctctgca atggtaatta acacaatcat attaggtggt aattgcaggt
     5401 tgtggaggca gtggctccct gctcctgctc taggtgggcg gagcctcagc cagctcagct
     5461 gaccgacttt gggtttcaag ctgctggagt tgaaggggag gaagggctgc aaggcaatgc
     5521 acacctaggt gtttacaggg tgtggtttgt gagctggcca cctgtttacc cactttacca
     5581 tggtttgtat aagctcctgc cctgagggcc actgatggca ggctttggtt caggactgct
     5641 cttgtgcagt gcagccttgg tttgaatcct ggcaggttgc cacttctctg tgactcagtt
     5701 tcctccccag caccctgcat cctaccctga gggtggtgtg ggaggggtag agactgaaac
     5761 ccagcactgc gttctgcttg ctggagtgct ggggtgagag tcagtttctc ccattgccag
     5821 agagagggct gggctgggcc tgactcctgg aagtggggct tccgtctagt ctactggtgt
     5881 tttggttgaa actaggagga ctttagacct cagggggatt agcctggact ggttggtgcc
     5941 tcagaactca attgccacgt catgtcacag gagagccctg atcgatggtg ataccaagaa
     6001 ggcaagagtg atatttttgt ccctttctaa gctctggatt tttcttaacc cgagaagaga
     6061 ctaagtgtaa gacatgaact gctggccacg tgatagagct agctagtatt ccatatgtta
     6121 gctgtatgca gtaagtgctc agagtatcct ggctgcacat agcaaacgat gcatctagaa
     6181 ggtactcaga tctggctacc gagtctatag aagaaggcgg ttccccttgg tgactcatgt
     6241 tccagatgac atccacaacc ctctctcagc ttgggcagtt tagagcaaca gttagatgtt
     6301 atgttatgac tccacaagac caggtaacaa ctctcaggtc ccaaagaaac ccaggacata
     6361 tggttatcta cggtgcctat tagcatgtgg aagtgcttgc tggcagccag gttcactcag
     6421 ttcctgtgac tctctgctct tatctctcct ccctgcacct tcccccagac ttctccagcc
     6481 caggaacgtc tgatgccaat caaaacctgc cattttgtcc aagtgtggtc ttcattcttt
     6541 tcttgcatcc tcttggtctt ctgctcttga ctcgccatcc tctcttttct cttcctctct
     6601 tgctctcccc gcaccttccc tttccagcct ggtctactcg gctggccagg ttctatttgg
     6661 tacttttttc cctgctctgg actcttccag acgcctctgg ctgttctctc cctcatatct
     6721 acaataaacg ccccctcctc agccataaaa aaaaaaaaaa aaaa
//
