LOCUS       NM_007574               1063 bp    mRNA    linear   ROD 19-DEC-2022
DEFINITION  Mus musculus complement component 1, q subcomponent, C chain
            (C1qc), mRNA.
ACCESSION   NM_007574
VERSION     NM_007574.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Mortensen SA, Sander B, Jensen RK, Pedersen JS, Golas MM, Jensenius
            JC, Hansen AG, Thiel S and Andersen GR.
  TITLE     Structure and activation of C1, the complex initiating the
            classical pathway of the complement cascade
  JOURNAL   Proc Natl Acad Sci U S A 114 (5), 986-991 (2017)
   PUBMED   28104818
REFERENCE   2  (bases 1 to 1063)
  AUTHORS   Hong S, Beja-Glasser VF, Nfonoyim BM, Frouin A, Li S, Ramakrishnan
            S, Merry KM, Shi Q, Rosenthal A, Barres BA, Lemere CA, Selkoe DJ
            and Stevens B.
  TITLE     Complement and microglia mediate early synapse loss in Alzheimer
            mouse models
  JOURNAL   Science 352 (6286), 712-716 (2016)
   PUBMED   27033548
REFERENCE   3  (bases 1 to 1063)
  AUTHORS   Liu KX, Edwards B, Lee S, Finelli MJ, Davies B, Davies KE and
            Oliver PL.
  TITLE     Neuron-specific antioxidant OXR1 extends survival of a mouse model
            of amyotrophic lateral sclerosis
  JOURNAL   Brain 138 (Pt 5), 1167-1181 (2015)
   PUBMED   25753484
REFERENCE   4  (bases 1 to 1063)
  AUTHORS   Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S,
            Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ,
            Jones AR, Amaral DG, Sestan N, Gage FH and Lein ES.
  TITLE     Conserved molecular signatures of neurogenesis in the hippocampal
            subgranular zone of rodents and primates
  JOURNAL   Development 140 (22), 4633-4644 (2013)
   PUBMED   24154525
REFERENCE   5  (bases 1 to 1063)
  AUTHORS   Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X,
            Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K,
            Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A and Mayr
            M.
  TITLE     Extracellular matrix secretion by cardiac fibroblasts: role of
            microRNA-29b and microRNA-30c
  JOURNAL   Circ Res 113 (10), 1138-1147 (2013)
   PUBMED   24006456
REFERENCE   6  (bases 1 to 1063)
  AUTHORS   Rossi V, Cseh S, Bally I, Thielens NM, Jensenius JC and Arlaud GJ.
  TITLE     Substrate specificities of recombinant mannan-binding
            lectin-associated serine proteases-1 and -2
  JOURNAL   J Biol Chem 276 (44), 40880-40887 (2001)
   PUBMED   11527969
REFERENCE   7  (bases 1 to 1063)
  AUTHORS   Nicholson-Weller A and Klickstein LB.
  TITLE     C1q-binding proteins and C1q receptors
  JOURNAL   Curr Opin Immunol 11 (1), 42-46 (1999)
   PUBMED   10047536
  REMARK    Review article
REFERENCE   8  (bases 1 to 1063)
  AUTHORS   Petry F, McClive PJ, Botto M, Morley BJ, Morahan G and Loos M.
  TITLE     The mouse C1q genes are clustered on chromosome 4 and show
            conservation of gene organization
  JOURNAL   Immunogenetics 43 (6), 370-376 (1996)
   PUBMED   8606057
REFERENCE   9  (bases 1 to 1063)
  AUTHORS   McClive PJ, Huang D and Morahan G.
  TITLE     C57BL/6 and C57BL/10 inbred mouse strains differ at multiple loci
            on chromosome 4
  JOURNAL   Immunogenetics 39 (4), 286-288 (1994)
   PUBMED   7907077
REFERENCE   10 (bases 1 to 1063)
  AUTHORS   Petry F, Reid KB and Loos M.
  TITLE     Isolation, sequence analysis and characterization of cDNA clones
            coding for the C chain of mouse C1q. Sequence similarity of
            complement subcomponent C1q, collagen type VIII and type X and
            precerebellin
  JOURNAL   Eur J Biochem 209 (1), 129-134 (1992)
   PUBMED   1396691
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB636871.1, CK332232.1 and AI385742.1.
            
            [WARNING] On Apr 24, 2023 this sequence was replaced by
            NM_007574.3.
            
            On Aug 31, 2006 this sequence version replaced NM_007574.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC043945.1, X66295.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-39                BB636871.1         2-40
            40-576              CK332232.1         1-537
            577-1063            AI385742.1         1-487               c
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 69.05 cM"
     gene            1..1063
                     /gene="C1qc"
                     /gene_synonym="Adib; C1qg; Ciqc"
                     /note="complement component 1, q subcomponent, C chain"
                     /db_xref="GeneID:12262"
                     /db_xref="MGI:MGI:88225"
     exon            1..71
                     /gene="C1qc"
                     /gene_synonym="Adib; C1qg; Ciqc"
                     /inference="alignment:Splign:2.1.0"
     exon            72..256
                     /gene="C1qc"
                     /gene_synonym="Adib; C1qg; Ciqc"
                     /inference="alignment:Splign:2.1.0"
     exon            257..1054
                     /gene="C1qc"
                     /gene_synonym="Adib; C1qg; Ciqc"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaacagtat gttcctgtct gggagaacag gacgtctctg tgattaggcc tgaagtccct
       61 tacaccctca ggatggtcgt tggacccagt tgccagcctc catgtggact ttgcctgctg
      121 ctgctgtttc ttctggccct accactcagg agccaggcca gcgctggctg ctatgggatc
      181 ccagggatgc caggcatgcc gggggcccct gggaaggacg ggcatgatgg actccagggg
      241 cccaagggag agccaggaat cccagccgtc cctgggaccc gaggacccaa gggtcagaag
      301 ggcgagcctg gcatgcctgg ccaccgtggg aaaaatggcc ccagggggac ctcagggttg
      361 ccaggggacc caggccccag ggggcctccg ggggagccag gtgtggaggg ccgatacaaa
      421 cagaagcacc agtcggtatt cacagtcacc cggcagacca cccagtaccc agaggccaac
      481 gccctcgtca ggttcaactc tgtggtcacc aaccctcagg ggcattacaa cccaagcaca
      541 gggaagttca cctgtgaagt gccgggcctc tactacttcg tctactacac atcgcatacg
      601 gccaacctgt gcgtgcacct gaacctcaac cttgccaggg tggccagctt ctgcgaccac
      661 atgttcaaca gcaagcaggt cagctccgga ggagtcctcc tgcggctcca gaggggcgat
      721 gaggtgtggc tatcagtcaa tgactacaat ggcatggtgg gcatagaggg ctccaacagc
      781 gtcttctctg gtttcctact gtttcccgac tagaacggca ggctgcttcc agcccccagc
      841 cacccacctc gctccctctg ctttccccat cctcactcag acctcttcct ccaggaagtc
      901 caccctggtt cctgatccat cggccctgta tctcctcaga gtttctctgg gaaccaccta
      961 atggtattat tcctgtggcc atttatcaat accttatgag actatttttt tgttcaggtg
     1021 gtgagataga gaaataaata gatcactaaa tacgaaaaaa aaa
//
