LOCUS       NM_020558               3028 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus C1D nuclear receptor co-repressor (C1d), transcript
            variant 1, mRNA.
ACCESSION   NM_020558
VERSION     NM_020558.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3028)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3028)
  AUTHORS   Jackson,R.A., Wu,J.S. and Chen,E.S.
  TITLE     C1D family proteins in coordinating RNA processing, chromosome
            condensation and DNA damage response
  JOURNAL   Cell Div 11, 2 (2016)
   PUBMED   27030795
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3028)
  AUTHORS   Nehls,P., Keck,T., Greferath,R., Spiess,E., Glaser,T.,
            Rothbarth,K., Stammer,H. and Werner,D.
  TITLE     cDNA cloning, recombinant expression and characterization of
            polypetides with exceptional DNA affinity
  JOURNAL   Nucleic Acids Res 26 (5), 1160-1166 (1998)
   PUBMED   9469821
REFERENCE   4  (bases 1 to 3028)
  AUTHORS   Zamir,I., Dawson,J., Lavinsky,R.M., Glass,C.K., Rosenfeld,M.G. and
            Lazar,M.A.
  TITLE     Cloning and characterization of a corepressor and potential
            component of the nuclear hormone receptor repression complex
  JOURNAL   Proc Natl Acad Sci U S A 94 (26), 14400-14405 (1997)
   PUBMED   9405624
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL603925.20, AK035169.1 and AK028702.1.
            
            On Aug 31, 2016 this sequence version replaced NM_020558.3.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK035169.1, AK028702.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-71                AL603925.20        15116-15186
            72-2134             AK035169.1         2-2064
            2135-2657           AK028702.1         2071-2593
            2658-3028           AK035169.1         2588-2958
FEATURES             Location/Qualifiers
     source          1..3028
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 9.89 cM"
     gene            1..3028
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /note="C1D nuclear receptor co-repressor"
                     /db_xref="GeneID:57316"
                     /db_xref="MGI:MGI:1927354"
     exon            1..112
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            113..259
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..547
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /note="nuclear DNA-binding protein; small unique nuclear
                     receptor corepressor"
                     /codon_start=1
                     /product="nuclear nucleic acid-binding protein C1D"
                     /protein_id="NP_065583.2"
                     /db_xref="CCDS:CCDS24451.1"
                     /db_xref="GeneID:57316"
                     /db_xref="MGI:MGI:1927354"
                     /translation="MAGEEMNEDYPVEIHESLTALESSLGAVDDMLKTMMAVSRNELL
                     QKLDPLEQAKVDLVSAYTLNSMFWVYLATQGVNPKEHPVKQELERIRVYMNRVKEITD
                     KKKAAKLDRGAASRFVKNALWEPKAKSTPKVANKGKSKH"
     exon            260..326
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            327..382
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /inference="alignment:Splign:2.1.0"
     exon            383..3028
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1055..1060
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /note="hexamer: AATAAA"
     polyA_site      1086
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /note="major polyA site"
     regulatory      2020..2025
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /note="hexamer: AATAAA"
     polyA_site      2049
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
     regulatory      2514..2519
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /note="hexamer: AATAAA"
     polyA_site      2535
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
     regulatory      2725..2730
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /note="hexamer: ATTAAA"
     polyA_site      2750
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
     regulatory      2948..2953
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
                     /note="hexamer: ATTAAA"
     polyA_site      2984
                     /gene="C1d"
                     /gene_synonym="1110036E10Rik; SUN-CoR"
ORIGIN      
        1 gaagtgcgca cgcgcacgac cgggagagac gcacgggcgg caggcagaag ccgtgtcatg
       61 gcgtcatcat cgtgcgacct atttcccgga gacaggcgtc cacggtattg agttggtcac
      121 aatggcaggt gaagaaatga atgaagatta tcccgtagaa attcacgagt ctttaacagc
      181 cctggagagc tccctgggtg ctgtggacga catgctgaag accatgatgg ctgtttctag
      241 aaacgagttg ttgcagaagt tggacccatt ggaacaagca aaggtggatt tagtttctgc
      301 atacacctta aattcaatgt tttgggttta tttggcaact caaggagtta atcccaaaga
      361 gcatccagtg aagcaggaac tggaaagaat cagagtctac atgaacagag ttaaagaaat
      421 aacagacaag aagaaggctg ccaagctgga cagaggtgct gcttcgagat ttgtcaagaa
      481 cgcactctgg gaacccaaag caaaaagcac accaaaagtg gctaataaag ggaaaagcaa
      541 acactaatct tttggttttg atgtacatgt tttcaaaaag tacatccttt ttaatcagtt
      601 tacaatgtag ttatgtgacc atgtggtgtt taaatggatt ccttttggaa ttcatgtata
      661 aatttacaca ttacatttgt gatactgaat cttttttttg ctgagaaaga ttaagttgtc
      721 tttgttgatt ttcatataaa gcatcatgat gtgtttaata ttgtaagata ttctataagc
      781 agttgtgaaa tccaaatgtt ctctgtaaac atttgtagtg tttgaaatga acaatgatat
      841 tatgaagtgt gctatctgta gactggaggt gtaaggacat ttgttttcag taatgatgag
      901 aaatacagtg acttaaatac ccactctgtt ttctgttcag ttagttcaac atgtttctgt
      961 gatttttttt tttttggagt aattgctgtc ttgatattca aagtacaaaa ttgaaacctt
     1021 aaggctgtac tttaattctt catgttccat ttaaaataaa atgttctcat taactctgat
     1081 ggaaaacacg gttgtatgtc ctgactggct ttggcttgat tcccttttaa taagtatggt
     1141 agctgggtag ctcacatgct tcttgctgtc cactgcgtga gtgaacaagc cctccagatg
     1201 aggcagtgtg agcagctcca ccaggtagag aaggctgatg agtcatggcg gctctctgtt
     1261 ctcttggtct cactcttaga atctttctga ctaagtattt cctaagccat gtggatgttt
     1321 tgaaatatct tctttattaa atactgcccc ttaggcacag gaggaatcaa attatattta
     1381 cattctgatt tatttttcca gggtgttcgt tatgatgaat tctacttatt aatgtctgag
     1441 ctcatataac cttgcttctc taggcccaca tagtcatgtg tagaagtgcc aaggatagct
     1501 aaggtttttt tgttgttgtt cttgagaatt agagttgtag aaattgtctg tgactaactt
     1561 ttaatatatg aatttcttta ttaggtagcg gatagtggaa ctggtctgaa gttatgatgg
     1621 actttgtaag gcatgctaaa atctgattca taaacattaa gtcaatagat gcagaaagtc
     1681 tcagctctga tatcagatag tttgtgatgt gaaagaacat tcatgagcat ttgtagttat
     1741 ttcactctgg gccattttaa ttctctgata atagtgaaag taacttcatt agagaaataa
     1801 gtgctttatg aagataactg tagaatgcat ttttaatgtt attcgctgca aagaaacttg
     1861 ggtcttgtat ttctcttttt aaatttcata aagaaaagag cttttaatgg aaattttcac
     1921 aattgcagaa aataattaac caaggtattt gtgaacaccc agcctatgtc ccacggaatt
     1981 ggatatcttt aacgagttct ctcagcatgc gtttgtagaa ataaaatatt ttaagtctgt
     2041 tctattttat tatagagttt gaaataatta ttacaacata ccaaggagct gtgacagttt
     2101 attaggttat ctgtgtatca caggccaaca cactgtgctc aagtctaggt ttgagagatg
     2161 atgtctgtag cccttgcgtt gtttttctga agcgttatgg aacagtagtc ttgattcaat
     2221 tcagtatttc agagtttcca gaaatcatag gaagttaccc tcactggcct tagccagaac
     2281 tatacaaggt ggagggttca cttattaagt gtagagtagt tattggtaac agtttattcc
     2341 gagtaatgct gttctgaaag ggacggtgtt agttgcatgt tttattaatc ttcttgggaa
     2401 tcaacataat tggaggaatc gcagacatgt agacattgat ctaaatgaaa tctttaatat
     2461 tttaatttaa aaattcttgt tcaaagatac agagtgggaa gtagaatatg ttaaataaag
     2521 ttttaaagat taaaacatgt agatgggttt ttaagaaact gaagtataaa aatctactta
     2581 agttactaaa gtggacacac tacaactttt aaaattgttt agaaacatga gtacttaaaa
     2641 acagtgtact gaaggtagac acttttttct taagtaggtt attgaaaaaa atacttttgg
     2701 attgatcatt tatgattctg ttatattaaa tttaaaccaa caaattccaa gagcttgttg
     2761 ggactttgtt aaacaacagg aagcaaaaga ggcactggcc ctcacagcag agtgactaag
     2821 cttgcccaga tggtcccagt ggtgtccagg gtccagatgt ttcagtggct tgactcatga
     2881 gcttgacggt gtccagatgt ttcagtgcct cttcctagct tgtgtgaata tgcagtggat
     2941 atactttatt aaatgtgaat atttctcttt ccttacattc taaatctaag acttgagttt
     3001 tggaactata aaccataagt tgtttagt
//
