LOCUS       NM_146193               3020 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus BTB domain containing 1 (Btbd1), mRNA.
ACCESSION   NM_146193 XM_982296
VERSION     NM_146193.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3020)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3020)
  AUTHORS   Tang,Y., Zhu,Q., Yang,L., Meng,Y., Zhang,G., Zhou,T., Wang,C.,
            Song,X., Su,Y.X. and Ye,J.
  TITLE     MiR-200b-5p inhibits tumor progression in salivary adenoid cystic
            carcinoma via targeting BTBD1
  JOURNAL   Cell Signal 109, 110748 (2023)
   PUBMED   37290676
  REMARK    GeneRIF: MiR-200b-5p inhibits tumor progression in salivary adenoid
            cystic carcinoma via targeting BTBD1.
REFERENCE   3  (bases 1 to 3020)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 3020)
  AUTHORS   Pisani,D.F., Coldefy,A.S., Elabd,C., Cabane,C., Salles,J., Le
            Cunff,M., Derijard,B., Amri,E.Z., Dani,C., Leger,J.J. and
            Dechesne,C.A.
  TITLE     Involvement of BTBD1 in mesenchymal differentiation
  JOURNAL   Exp Cell Res 313 (11), 2417-2426 (2007)
   PUBMED   17462629
  REMARK    GeneRIF: BTBD1 is a key protein of balance between adipogenesis and
            myogenesis.
REFERENCE   5  (bases 1 to 3020)
  AUTHORS   Pisani,D.F., Cabane,C., Derijard,B. and Dechesne,C.A.
  TITLE     The topoisomerase 1-interacting protein BTBD1 is essential for
            muscle cell differentiation
  JOURNAL   Cell Death Differ 11 (11), 1157-1165 (2004)
   PUBMED   15486563
  REMARK    GeneRIF: BTBD1 is essential for myogenic differentiation
REFERENCE   6  (bases 1 to 3020)
  AUTHORS   Xu,L., Yang,L., Moitra,P.K., Hashimoto,K., Rallabhandi,P., Kaul,S.,
            Meroni,G., Jensen,J.P., Weissman,A.M. and D'Arpa,P.
  TITLE     BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the
            RBCC/tripartite motif protein, TRIM5delta
  JOURNAL   Exp Cell Res 288 (1), 84-93 (2003)
   PUBMED   12878161
REFERENCE   7  (bases 1 to 3020)
  AUTHORS   Carim-Todd,L., Sumoy,L., Andreu,N., Estivill,X. and Escarceller,M.
  TITLE     Identification and characterization of BTBD1, a novel BTB domain
            containing gene on human chromosome 15q24
  JOURNAL   Gene 262 (1-2), 275-281 (2001)
   PUBMED   11179693
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC072618.1.
            
            On or before May 4, 2006 this sequence version replaced
            XM_982296.1, NM_146193.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC072618.1, SRR1660811.59640.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..3020
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 45.71 cM"
     gene            1..3020
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /note="BTB domain containing 1"
                     /db_xref="GeneID:83962"
                     /db_xref="MGI:MGI:1933765"
     exon            1..459
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..1507
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /note="glucose signal-repressing protein; BTB (POZ) domain
                     containing 1"
                     /codon_start=1
                     /product="BTB/POZ domain-containing protein 1"
                     /protein_id="NP_666305.2"
                     /db_xref="CCDS:CCDS21407.1"
                     /db_xref="GeneID:83962"
                     /db_xref="MGI:MGI:1933765"
                     /translation="MASLGSAAAGEPATGAEAEPGPPAPPPPPPPPPAPSPSALGPLL
                     PLQREPLYNWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAAAAGGPQRIPAHRFV
                     LAAGSAVFDAMFNGGMATTSAEIELPDVEPAAFLALLRFLYSDEVQIGPETVMTTLYT
                     AKKYAVPALEAHCVEFLTKHLRADNAFMLLTQARLFDEPQLASLCLDTIDKSTVDAIS
                     AEGFTDIDIDTLCAVLERDTLSIRESRLFGAIVRWAEAECQRQQLAVTFGNKQKVLGK
                     ALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYIDRPRCCLRGK
                     ECCINRFQQVESRWGYSGTSDRIRFTVNRRISVVGFGLYGSIHGPTDYQVNIQIIEYE
                     KKQTLGQNDTGFSCDGTANTFRVMFKEPIEILPNVCYTACATLKGPDSHYGTKGLKKV
                     VHETPAASKTVFLFFSSPGNNNGTSIEDGQIPEIIFYT"
     exon            460..616
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            617..722
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            723..920
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1113
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1201
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1348
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1349..3001
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1541..1546
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /note="hexamer: CATAAA"
     polyA_site      1562
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
     regulatory      2979..2984
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3001
                     /gene="Btbd1"
                     /gene_synonym="1190005H08Rik"
                     /note="major polyA site"
ORIGIN      
        1 ccgggtgctc gcagcttgag cggagccgcg cagcaggagg atggcctcgc tcgggtcagc
       61 cgcggccggg gagccggcga ccggagctga ggcggagccc ggccctccgg ccccgccgcc
      121 gcctccgccg ccgccaccgg ctccctcgcc gtccgctctc gggccgctgc tgcccctgca
      181 gcgcgagccg ctgtacaact ggcaggccac caaggcgtcg ctcaaggagc gcttcgcctt
      241 cctcttcaac tcggagctgc tgagcgatgt gcgtttcgtg ctgggcaagg gccgaggcgc
      301 ggcggccgcc gggggcccgc agcgcatccc cgcccaccgc ttcgtgctgg cggccggcag
      361 cgcggtcttc gacgccatgt tcaacggcgg catggccacg acgtcggccg agatcgagct
      421 gccggacgtg gagcccgccg ccttcctggc gctgctgaga tttttgtatt cagacgaagt
      481 tcaaattggt ccagaaaccg ttatgaccac tctttatact gctaagaaat atgcagtccc
      541 tgccttggaa gcacattgcg tagaatttct caccaaacat cttagggcag ataatgcctt
      601 tatgttgctt actcaggcgc ggttgttcga tgagccccag ctggctagtc tttgtctgga
      661 caccatagac aagagcacag tggatgcaat cagtgcggag gggtttactg atattgacat
      721 agatacactc tgtgcagttc tagaaagaga cacactgagt atccgagaaa gtcgactttt
      781 tggagctatt gtacgttggg cagaagcaga gtgtcagaga caacaactgg ctgtgacatt
      841 tggaaacaaa cagaaagttc taggaaaagc actttcctta atccgcttcc cactgatgac
      901 aattgaggag tttgcagcag gtcctgctca atctggaatt ttgtcagacc gtgaagtggt
      961 aaacctcttt cttcatttta ccgtcaatcc taaaccccga gtagagtaca ttgatcggcc
     1021 acgatgctgc ctcagaggaa aggagtgctg catcaaccga ttccagcaag tagagagccg
     1081 ctggggttac agtgggacaa gcgatcgcat caggttcaca gttaacagaa gaatctctgt
     1141 agttggattt ggtttgtatg gatctattca cgggcccacg gattatcaag tgaatataca
     1201 gatcattgaa tatgagaaaa aacaaacctt gggacagaat gatactggat ttagttgtga
     1261 tgggactgct aacacattca gggtcatgtt caaagaacct atagagatcc tgcccaatgt
     1321 ctgttacaca gcgtgcgcaa cactcaaggg cccagattct cactatggca caaaaggact
     1381 gaagaaagta gtgcatgaga cccctgctgc aagcaagact gttttcctat ttttcagttc
     1441 ccctggcaat aacaatggca catcaataga agatggacaa ataccagaaa taatatttta
     1501 tacataatct agtgttaacc attcagtcta atctcaaaag cataaacaac tggccacaaa
     1561 tagtttgagt gtcttgagta tttataatta cagattaaga aacattttag tttcttagaa
     1621 gtaaaatagt taatttaaat ctctgcatga ttcgaagcaa agagaactgg atgtgtgtgt
     1681 aaattgccgt cttttctgct tcgtcttgtg tgatttcgta gatccgctga ctcgtgatct
     1741 ttcagtagtt tgggaattga gagattcttg tcataatagc agatgtgggt gtttgatttt
     1801 taaaactttt gttttaactg ttttgaaagt tagatgagat gggtgagtat tcctacaaaa
     1861 ttctttttaa ctcaaataac taatttcaga aaattaagaa aactgacttt atatttgggg
     1921 ttttcaaata tgtggtcatt accttttgga ataatgccta gaaaacactc aagaaaagtt
     1981 tcagtgcatt tacagggaag gtattctgta acagtataga agtgcatcac atagcactgt
     2041 tttacagctg gaagtggagt ttgtataaat tcacaatgtg atataaacag atcgaaggga
     2101 ttatctgaga tggattcttt atcactccca tcccactaag ccagtcatgg gtgctgcagt
     2161 gatccagatg actgagatgt gacagatgcc aacagatggc cactgcagca ctgcaatgcc
     2221 cttcacagca agaagggggt agaataccaa gatccctaac agctgcgctg aaccataaag
     2281 ctgtccatgt ccagccagtc actcctgctg aagaggaaga aggctttgtg tcatctacat
     2341 agttccaccc aagaagtaaa aatgctacag taagagtgga tcaaagggat atttggcagt
     2401 gtgacatttc tacattttta tataaagcag atttttaaaa tacaagtaag ataatatttt
     2461 cccttgaaaa tgattatctt acaaaaaaac ccttgtataa ttaagcttaa ggtctatcag
     2521 tctatcagat agttgtggga aattattaaa aataagaatt cttttaagta tcaacttaag
     2581 aatttttcta aataggatat aaaagttttc atcaaaagta atattttgta ttttcaagat
     2641 ggcagggagg tgatgtgttg gtggccagga tctcttgaag ttgttgaaga aagggaactg
     2701 ttttcagtct gctctggtac tatgatctta tgggtctaag cctcagttag cgggaatgcc
     2761 catggaatgt gtgattctgc ttaactgaag agaagtaaag actgtgtagt aaccattcct
     2821 taaccagtgt tgcatgccag aggtaagtta gtgctttctg accattgggg cattcgcatg
     2881 ccttgtgctt tactgaacaa ctgtaactga atgtagtcat ggaaggaaca agatacggaa
     2941 ccactcactg acattgggac atcacctgga atttttaaaa taaatttatc ctttttgttt
     3001 aaaaaaaaaa aaaaaaaaaa
//
