LOCUS       NM_009768               1752 bp    mRNA    linear   ROD 19-AUG-2024
DEFINITION  Mus musculus basigin (Bsg), transcript variant 1, mRNA.
ACCESSION   NM_009768
VERSION     NM_009768.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1752)
  AUTHORS   Dai,P., Ma,C., Jiang,T., Shi,J., Liu,S., Zheng,M., Zhou,Y., Li,X.,
            Liu,Y. and Chen,H.
  TITLE     CD147 mediates S protein pseudovirus of SARS-CoV-2 infection and
            its induction of spermatogonia apoptosis
  JOURNAL   Endocrine 85 (3), 1435-1445 (2024)
   PUBMED   38824220
  REMARK    GeneRIF: CD147 mediates S protein pseudovirus of SARS-CoV-2
            infection and its induction of spermatogonia apoptosis.
REFERENCE   2  (bases 1 to 1752)
  AUTHORS   Feigelman,G., Simanovich,E., Brockmeyer,P. and Rahat,M.A.
  TITLE     EMMPRIN promotes spheroid organization and metastatic formation:
            comparison between monolayers and spheroids of CT26 colon carcinoma
            cells
  JOURNAL   Front Immunol 15, 1374088 (2024)
   PUBMED   38725999
  REMARK    GeneRIF: EMMPRIN promotes spheroid organization and metastatic
            formation: comparison between monolayers and spheroids of CT26
            colon carcinoma cells.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1752)
  AUTHORS   Lv,J.J., Wang,H., Zhang,C., Zhang,T.J., Wei,H.L., Liu,Z.K.,
            Ma,Y.H., Yang,Z., He,Q., Wang,L.J., Duan,L.L., Chen,Z.N. and
            Bian,H.
  TITLE     CD147 Sparks Atherosclerosis by Driving M1 Phenotype and Impairing
            Efferocytosis
  JOURNAL   Circ Res 134 (2), 165-185 (2024)
   PUBMED   38166463
  REMARK    GeneRIF: CD147 Sparks Atherosclerosis by Driving M1 Phenotype and
            Impairing Efferocytosis.
REFERENCE   4  (bases 1 to 1752)
  AUTHORS   Talvi,S., Jokinen,J., Sipila,K., Rappu,P., Zhang,F.P., Poutanen,M.,
            Rantakari,P. and Heino,J.
  TITLE     Embigin deficiency leads to delayed embryonic lung development and
            high neonatal mortality in mice
  JOURNAL   iScience 27 (2), 108914 (2024)
   PUBMED   38318368
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1752)
  AUTHORS   Kanekura,T.
  TITLE     CD147/Basigin Is Involved in the Development of Malignant Tumors
            and T-Cell-Mediated Immunological Disorders via Regulation of
            Glycolysis
  JOURNAL   Int J Mol Sci 24 (24), 17344 (2023)
   PUBMED   38139173
  REMARK    GeneRIF: CD147/Basigin Is Involved in the Development of Malignant
            Tumors and T-Cell-Mediated Immunological Disorders via Regulation
            of Glycolysis.
            Review article
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1752)
  AUTHORS   Serikawa,T., Montagutelli,X., Simon-Chazottes,D. and Guenet,J.L.
  TITLE     Polymorphisms revealed by PCR with single, short-sized, arbitrary
            primers are reliable markers for mouse and rat gene mapping
  JOURNAL   Mamm Genome 3 (2), 65-72 (1992)
   PUBMED   1617216
REFERENCE   7  (bases 1 to 1752)
  AUTHORS   Simon-Chazottes,D., Matsubara,S., Miyauchi,T., Muramatsu,T. and
            Guenet,J.L.
  TITLE     Chromosomal localization of two cell surface-associated molecules
            of potential importance in development: midkine (Mdk) and basigin
            (Bsg)
  JOURNAL   Mamm Genome 2 (4), 269-271 (1992)
   PUBMED   1347477
REFERENCE   8  (bases 1 to 1752)
  AUTHORS   Miyauchi,T., Masuzawa,Y. and Muramatsu,T.
  TITLE     The basigin group of the immunoglobulin superfamily: complete
            conservation of a segment in and around transmembrane domains of
            human and mouse basigin and chicken HT7 antigen
  JOURNAL   J Biochem 110 (5), 770-774 (1991)
   PUBMED   1783610
REFERENCE   9  (bases 1 to 1752)
  AUTHORS   Kanekura,T., Miyauchi,T., Tashiro,M. and Muramatsu,T.
  TITLE     Basigin, a new member of the immunoglobulin superfamily: genes in
            different mammalian species, glycosylation changes in the molecule
            from adult organs and possible variation in the N-terminal
            sequences
  JOURNAL   Cell Struct Funct 16 (1), 23-30 (1991)
   PUBMED   2032306
REFERENCE   10 (bases 1 to 1752)
  AUTHORS   Miyauchi,T., Kanekura,T., Yamaoka,A., Ozawa,M., Miyazawa,S. and
            Muramatsu,T.
  TITLE     Basigin, a new, broadly distributed member of the immunoglobulin
            superfamily, has strong homology with both the immunoglobulin V
            domain and the beta-chain of major histocompatibility complex class
            II antigen
  JOURNAL   J Biochem 107 (2), 316-323 (1990)
   PUBMED   2361961
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC151828.3 and AY089967.1.
            
            On Oct 11, 2006 this sequence version replaced NM_009768.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.350166.1,
                                           SRR7345562.3696475.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-142               AC151828.3         112732-112873
            143-1666            AY089967.1         1-1524
            1667-1752           AC151828.3         120268-120353
FEATURES             Location/Qualifiers
     source          1..1752
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..1752
                     /gene="Bsg"
                     /gene_synonym="CD147; EMMPRIN; HT-7"
                     /note="basigin"
                     /db_xref="GeneID:12215"
                     /db_xref="MGI:MGI:88208"
     exon            1..227
                     /gene="Bsg"
                     /gene_synonym="CD147; EMMPRIN; HT-7"
                     /inference="alignment:Splign:2.1.0"
     CDS             161..1330
                     /gene="Bsg"
                     /gene_synonym="CD147; EMMPRIN; HT-7"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; HT7 antigen; membrane glycoprotein gp42; basic
                     immunoglobulin superfamily; neurothelin; 5A11/Basigin; gp
                     42"
                     /codon_start=1
                     /product="basigin isoform 1 precursor"
                     /protein_id="NP_033898.1"
                     /db_xref="CCDS:CCDS23985.1"
                     /db_xref="GeneID:12215"
                     /db_xref="MGI:MGI:88208"
                     /translation="MAAALLLALAFTLLSGQGACAAAGFLKAPLSQERWAGGSVVLHC
                     EAVGSPIPEIQWWFEGNAPNDSCSQLWDGARLDRVHIHAAYRQHAASSLSVDGLTAED
                     TGTYECRASSDPDRNHLTRPPRVKWVRAQASVVVLEPGTIQTSVQEVNSKTQLTCSLN
                     SSGVDIVGHRWMRGGKVLQEDTLPDLHTKYIVDADDRSGEYSCIFLPEPVGRSEINVE
                     GPPRIKVGKKSEHSSEGELAKLVCKSDASYPPITDWFWFKTSDTGEEEAITNSTEANG
                     KYVVVSTPEKSQLTISNLDVNVDPGTYVCNATNAQGTTRETISLRVRSRMAALWPFLG
                     IVAEVLVLVTIIFIYEKRRKPDQTLDEDDPGAAPLKGSGTHMNDKDKNVRQRNAT"
     exon            228..575
                     /gene="Bsg"
                     /gene_synonym="CD147; EMMPRIN; HT-7"
                     /inference="alignment:Splign:2.1.0"
     exon            576..732
                     /gene="Bsg"
                     /gene_synonym="CD147; EMMPRIN; HT-7"
                     /inference="alignment:Splign:2.1.0"
     exon            733..815
                     /gene="Bsg"
                     /gene_synonym="CD147; EMMPRIN; HT-7"
                     /inference="alignment:Splign:2.1.0"
     exon            816..958
                     /gene="Bsg"
                     /gene_synonym="CD147; EMMPRIN; HT-7"
                     /inference="alignment:Splign:2.1.0"
     exon            959..1241
                     /gene="Bsg"
                     /gene_synonym="CD147; EMMPRIN; HT-7"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1266
                     /gene="Bsg"
                     /gene_synonym="CD147; EMMPRIN; HT-7"
                     /inference="alignment:Splign:2.1.0"
     exon            1267..1752
                     /gene="Bsg"
                     /gene_synonym="CD147; EMMPRIN; HT-7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1723..1728
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bsg"
                     /gene_synonym="CD147; EMMPRIN; HT-7"
                     /note="hexamer: AATAAA"
     polyA_site      1742
                     /gene="Bsg"
                     /gene_synonym="CD147; EMMPRIN; HT-7"
                     /note="major polyA site"
ORIGIN      
        1 gtagcgcgag cgggagcggc ggacgctggg tacgtgccta ctccctgtgt gcctggcgcc
       61 ccgccctgcg acgccgcgtg cgtgcgtacg tgcgtgcctg cgtgcgcgcg ccccgccctt
      121 cttatagagc cgcagtgggg cagctcctgg acgaggcgac atggcggcgg cgctgctgct
      181 ggcgctggcc ttcacgctct tgagcggcca aggcgcctgc gcggcggctg gtttcctcaa
      241 ggcaccactg tcgcaggagc ggtgggcggg gggcagcgtg gtcctgcact gtgaggctgt
      301 gggcagcccc atccccgaga tccagtggtg gtttgaaggg aatgctccaa acgacagctg
      361 ctcccagctc tgggatggtg cccggctgga ccgtgttcac atccatgccg cctaccgtca
      421 gcatgcagcc agttcgctct ctgttgatgg gctcaccgca gaggacacag gcacttacga
      481 gtgccgggcc agcagtgacc cagaccgcaa ccaccttact cggccaccca gggtcaagtg
      541 ggtccgtgcc caggcgagcg tggtggtcct tgaaccgggc accatccaaa cctctgtcca
      601 ggaagtcaac tccaaaacac agcttacctg ctctttgaac agcagtggcg ttgacatcgt
      661 tggccaccgc tggatgagag gtggcaaggt actgcaggag gacactctgc ccgacctgca
      721 tacgaagtac atagtggacg cagatgaccg ctctggggaa tattcctgca tcttccttcc
      781 tgagcctgtg ggcagaagcg agatcaatgt ggaagggcca cccaggatca aggtcggaaa
      841 gaaatcagag cattccagtg agggagagct tgcgaaactg gtctgcaagt ccgatgcatc
      901 ctaccctcct attacagatt ggttctggtt taagacctct gacactgggg aagaagaggc
      961 aatcaccaat agcactgaag ccaatggcaa gtatgtggtg gtatccacgc ctgagaagtc
     1021 acagctgacc atcagcaacc ttgacgtaaa tgttgaccct ggcacctacg tgtgtaatgc
     1081 caccaacgcc cagggcacta ctcgggaaac catctcactg cgtgtgcgga gccgcatggc
     1141 agccctctgg cccttcctag gcatcgtggc tgaggtcctg gtgttggtta ccatcatctt
     1201 tatctatgag aagaggcgga agccagacca gaccctggac gaggatgacc ctggcgccgc
     1261 cccactgaag ggcagtggaa ctcacatgaa tgacaaggac aagaatgtac gccagaggaa
     1321 cgccacctga gtggtggggc aggcggggga ggggaggtgc ccagggtgcc tgaccccagg
     1381 ccagcgtcta cctccactcc agtatcccat cctgtcccga tttgaaccta cccaacccaa
     1441 cctatcccaa cccaagtgaa gacagagcct taccttacag aaaacccacc tggaagaagc
     1501 aagccacttg cagcccctgt ttctaattta aactaaatga ggtttctatg cagacaatcc
     1561 attccttagg ggtttatgtt tttatttttc cttcccttct gaagtgttgt cactacagcc
     1621 ctgtggagtg ggggaatggg gccttgtcct tggtcaggag ggaaggccag tgcatgctct
     1681 gacttactgt tggagggggc tgggcctgct ggaacccccc caaataaaga cctaccccac
     1741 catgtgtgtg tc
//
