LOCUS       NM_207583               4117 bp    mRNA    linear   ROD 02-JUL-2024
DEFINITION  Mus musculus bone morphogenic protein/retinoic acid inducible
            neural-specific 2 (Brinp2), mRNA.
ACCESSION   NM_207583 XM_136316
VERSION     NM_207583.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4117)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4117)
  AUTHORS   Berkowicz,S.R., Featherby,T.J., Whisstock,J.C. and Bird,P.I.
  TITLE     Mice Lacking Brinp2 or Brinp3, or Both, Exhibit Behaviors
            Consistent with Neurodevelopmental Disorders
  JOURNAL   Front Behav Neurosci 10, 196 (2016)
   PUBMED   27826231
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4117)
  AUTHORS   Terashima,M., Kobayashi,M., Motomiya,M., Inoue,N., Yoshida,T.,
            Okano,H., Iwasaki,N., Minami,A. and Matsuoka,I.
  TITLE     Analysis of the expression and function of BRINP family genes
            during neuronal differentiation in mouse embryonic stem
            cell-derived neural stem cells
  JOURNAL   J Neurosci Res 88 (7), 1387-1393 (2010)
   PUBMED   20025061
REFERENCE   4  (bases 1 to 4117)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC076572.1 and CO043107.1.
            
            On Mar 12, 2009 this sequence version replaced NM_207583.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC076572.1, AK032297.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849376 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4009              BC076572.1         1-4009
            4010-4117           CO043107.1         1-108               c
FEATURES             Location/Qualifiers
     source          1..4117
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 68.27 cM"
     gene            1..4117
                     /gene="Brinp2"
                     /gene_synonym="6430517E21Rik; Fam5b; mKIAA1747"
                     /note="bone morphogenic protein/retinoic acid inducible
                     neural-specific 2"
                     /db_xref="GeneID:240843"
                     /db_xref="MGI:MGI:2443333"
     exon            1..744
                     /gene="Brinp2"
                     /gene_synonym="6430517E21Rik; Fam5b; mKIAA1747"
                     /inference="alignment:Splign:2.1.0"
     exon            745..1089
                     /gene="Brinp2"
                     /gene_synonym="6430517E21Rik; Fam5b; mKIAA1747"
                     /inference="alignment:Splign:2.1.0"
     CDS             821..3172
                     /gene="Brinp2"
                     /gene_synonym="6430517E21Rik; Fam5b; mKIAA1747"
                     /note="protein FAM5B; family with sequence similarity 5,
                     member B; BMP/retinoic acid-inducible neural-specific
                     protein 2"
                     /codon_start=1
                     /product="BMP/retinoic acid-inducible neural-specific
                     protein 2 precursor"
                     /protein_id="NP_997466.2"
                     /db_xref="CCDS:CCDS15401.1"
                     /db_xref="GeneID:240843"
                     /db_xref="MGI:MGI:2443333"
                     /translation="MRWPCSSWFRGLWPEAAPWAVLLALGVPGWVLAVSATVAAVVPE
                     QHVSSAGQAPLDWLLTDRGPFHRAQEYADFMERYRQGFTTRYRIYREFARWKVNNLAL
                     ERRDFFSLPLPLAPEFVRNIRLLGRRPNLQQVTENLIKKYGTHFLLSATLGGEESLTI
                     FVDKRKLSRKSETTGGIPVVGGTGNSSAVSLETLHQLAASYFIDRESTLRRLHHIQIA
                     TGAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKVQLLGLQVLLPEHLRERFVAAA
                     LSYITCSSEGELVCRENDCWCKCSPTFPECNCPDADIQAMEDSLLQIQDSWATHNRQF
                     EESEEFQTLLKRLPSDRFLNSTAISQYWTMDSNLQHRYQQLGASLKVLLKKMHRIVRR
                     LFNLCKRCHRQPRFRLPKERSLSFWWNRIQSLLYCGESTFPGTFLEQSHSCTCPYDQS
                     SCQGPIPCALGEGPACAHCASDNSTRCGSCNPGYVLAQGLCRPEVAESLENFLGLETD
                     LQDLELKYLLQKRDSRIEVHSIFISNDMRLGSWFDPSWRKRMLLTLKSNKYKPGLVHV
                     MLALSLQICLTKNSTLEPVMAIYVNPFGGSHSESWFMPVNEGNFPDWERTNVDAAAQC
                     QNWTITLGNRWKTFFETVHVYLRSRIKSLDDSSNETIYYEPLEMTDPSKNLGYMKINT
                     LQVFGYSLPFDPDAIRDLILQLDYPYTQGSQDSALLQLIELRDRVNQLSPPGKVRLDL
                     FSCLLRHRLKLANNEVGRIQSSLRAFNSKLPNPVEYETGKLCS"
     exon            1090..1280
                     /gene="Brinp2"
                     /gene_synonym="6430517E21Rik; Fam5b; mKIAA1747"
                     /inference="alignment:Splign:2.1.0"
     exon            1281..1489
                     /gene="Brinp2"
                     /gene_synonym="6430517E21Rik; Fam5b; mKIAA1747"
                     /inference="alignment:Splign:2.1.0"
     exon            1490..1595
                     /gene="Brinp2"
                     /gene_synonym="6430517E21Rik; Fam5b; mKIAA1747"
                     /inference="alignment:Splign:2.1.0"
     exon            1596..1832
                     /gene="Brinp2"
                     /gene_synonym="6430517E21Rik; Fam5b; mKIAA1747"
                     /inference="alignment:Splign:2.1.0"
     exon            1833..2055
                     /gene="Brinp2"
                     /gene_synonym="6430517E21Rik; Fam5b; mKIAA1747"
                     /inference="alignment:Splign:2.1.0"
     exon            2056..4101
                     /gene="Brinp2"
                     /gene_synonym="6430517E21Rik; Fam5b; mKIAA1747"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      4026
                     /gene="Brinp2"
                     /gene_synonym="6430517E21Rik; Fam5b; mKIAA1747"
                     /note="major polyA site"
ORIGIN      
        1 gtgacactgg ttaggtacgg accgggaagc cggagtgggg acgcgccggg ctgcagctcc
       61 aggatggaat ccgcctgcct gccgcgcggc tcgcggctca acccgcagcg cctccgctga
      121 gctcgacggg ttccggagga cttggaaatg cacctgccgc gcgctccgag gacaccagca
      181 ggtcctcagg cagccgaagg agcccagacg cctgaggaac gatttctgtc catgtacaag
      241 gcacagattt cggatgacag ggcgggtgag tctctttaga gttggaaaaa aaagaaggca
      301 agatcttggg tttcacctcg gtcgagggac aggggacttc tcagttggct tcccactttc
      361 ctcacctctc ccacgccgcg tgcgacccag cctagtgctg atcccacttc acagatgctg
      421 tgggtgcctg ggatgctcgc tgctccacgg caaggcagca ggcaagtggt ctaaaagctg
      481 ccgccgcggc ggcggcggcg acagcaaagc ccagagcagg agaatttgaa aagagacatc
      541 cgttccctct cacaagctga gggggtggca tttcatattt ccccaaagga gaaagagcca
      601 caagaaatca tgaagtaaaa actttggaag gctgccactg gagatgttgc acaaaaatca
      661 ggcgtctttt gggagtctcc tcgcagtcct tggtggtttg gggagcagct gatacagcaa
      721 gaaggactct tacaaggatt caagtttggc gccctggagg agcagcgcgg agtgggagag
      781 cttggcgaga gaatgaagac actaaccgcc tgggagaagc atgaggtggc cgtgcagctc
      841 ttggtttaga gggctttggc cggaggccgc cccatgggca gtcctgctgg cgctaggcgt
      901 acccgggtgg gtgctggctg tctcggccac ggtggccgct gtggtcccgg aacagcatgt
      961 ctcctcagct ggccaggctc ccctggactg gctgctcaca gaccgaggcc ccttccaccg
     1021 agcccaggag tatgctgatt tcatggagcg ttaccgccag gggttcacca ccagatacag
     1081 gatctacagg gagtttgccc gatggaaagt gaacaacttg gccctagaaa ggagagattt
     1141 cttcagtttg cccctgcctc tcgccccaga gtttgtccgc aatatccgcc tccttggaag
     1201 gagacccaat ctgcaacagg ttactgaaaa cctcatcaaa aagtacggca ctcatttctt
     1261 actttctgct actcttggag gagaagagtc tctgaccatt tttgtggaca agaggaaact
     1321 aagcagaaag tcagaaacaa caggaggtat ccctgtagtt gggggcactg ggaacagctc
     1381 cgctgtgtct ctggaaaccc tgcaccagct ggctgcctcc tacttcattg acagagagag
     1441 cacactgcgc agacttcacc atatccaaat agccacaggg gccataaagg tcacagagac
     1501 caggactggt ccactgggct gcagcaacta tgacaacctg gactcagtca gctctgtcct
     1561 ggttcagagt ccagagaaca aggtgcagtt actgggcctg caggtgctgc tccctgaaca
     1621 cctgcgtgag cggttcgtgg ctgcagcact cagctacatc acatgcagtt ctgagggcga
     1681 gctggtctgc agggagaatg actgctggtg caagtgcagc cccacattcc cggaatgcaa
     1741 ctgtcctgat gctgacattc aggctatgga agacagcttg ctgcagatcc aagactcctg
     1801 ggccactcac aacaggcagt ttgaagagtc cgaagaattc cagaccctgc tgaagaggct
     1861 ccccagtgac cggttcctga actccacagc catctcccag tactggacca tggactctaa
     1921 cctccagcac cgttatcagc agctgggagc cagcttgaaa gtcctgttaa agaagatgca
     1981 ccggatcgtc cgccgcctct tcaatctctg caagcgctgt catcggcagc ctcgcttccg
     2041 cctgcccaag gagagatcct tgtctttctg gtggaaccga atccagtccc ttctctactg
     2101 tggagaaagc accttccctg ggacgttcct ggaacagagc cacagctgca cctgccccta
     2161 tgaccaatct tcctgccagg gccccatccc atgtgccttg ggggaagggc ctgcatgtgc
     2221 tcactgtgct tcagacaatt ccacgcgctg tgggagttgt aaccctggtt atgtgctagc
     2281 ccagggactg tgtcggccag aggtagctga gtccctggag aacttccttg ggctggagac
     2341 agacctgcag gaccttgagc tgaagtacct gctgcagaag cgagatagcc gcattgaggt
     2401 acactccatc tttatcagca atgacatgcg cctgggcagc tggtttgatc cttcctggag
     2461 gaagcggatg ctcctgacct tgaagagcaa caagtacaag cccgggctgg tgcatgtgat
     2521 gttggccttg tccttgcaga tctgcctcac taagaacagc accctggaac cggtcatggc
     2581 catctacgtg aacccctttg ggggcagcca ctcagagagc tggttcatgc ctgttaatga
     2641 gggcaacttc ccagactggg aaaggactaa tgtagacgca gctgcccagt gccaaaactg
     2701 gactattact ttggggaaca ggtggaagac tttttttgag acagtccatg tttacctacg
     2761 gagccgaatc aagtccctgg atgacagctc caacgagaca atctactatg agcccctgga
     2821 gatgactgat ccctccaaga atttgggcta catgaaaatc aacaccttgc aggtctttgg
     2881 ctacagcctg ccctttgacc cggatgctat ccgagattta attctccagc tggactaccc
     2941 gtatactcaa ggttcccagg actctgcact cttacaactc attgagctta gagaccgggt
     3001 gaaccaactc tctccccctg gcaaagtccg gctcgacctt ttctcttgct tgctccggca
     3061 taggctcaag ctggccaaca atgaggtggg caggatccag tcctccctga gagcttttaa
     3121 ttccaagctg ccaaatcctg tggagtatga gacgggcaaa ctctgtagct aatgggggga
     3181 actaccccag tgctggtcag agagctgaac cacacattca gggtgcaaag ataatccaag
     3241 ccctcacctc agtgccaaca gagtgcttcc aagagacctt tagcacctgg gagatgggag
     3301 ctcaaggctt ggactgaagc aggcgaaaga caatgaaaca gccactgcac atgtgcacac
     3361 gtgcgtacaa cgccctacca cacacactca cagggaggcc acagcccagc agcctcgaat
     3421 ctgtaaagtc ggtgctctct aaaatgaatg cagttgaaga agagctaagg gagagatcaa
     3481 agcgggctaa atcaggaaag aactgactga agaaaaatgc ttcaaagtga ttcttgtcac
     3541 ggaggatagc aagaggggac agaagtggga ggggtgggga cctcccctct gtggagtcac
     3601 ttttgtattc tttttaacca gatttcttaa aatgttgttg ttccgtgact cccagcactg
     3661 cttcttactt tttgtacagc gcctccctgc gccctggagg cctccctgca ccctggaggc
     3721 cttgggtcta ccgctcttgg tgtccttagg aagtgtgtgc agtgctaggc agaggagccc
     3781 acgctaaggg caggccacag cctccttgct caatcgcccg cccacttctt cctcctgcca
     3841 gctccctcac ttccttggcc tccccagttt cagagttttg acttgttcca agagcccctc
     3901 acagttcatc cggagccctc ttcccacagc acctgtctgt tcaaggaagc agttttgtca
     3961 agttagagag acaacatata tggaaatgtt ctttttttaa aaaaaaaaac aacaaaacaa
     4021 aaaatattta ttttgtgatt gtttttcttg tcaacctact tcagtcacat gaacctatga
     4081 gtaaagtttt acttggttta aaaaaaaaaa aaaaaaa
//
