LOCUS       NM_175682                997 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus BRICHOS domain containing 5 (Bricd5), mRNA.
ACCESSION   NM_175682
VERSION     NM_175682.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 997)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 997)
  AUTHORS   Katzen,J., Wagner,B.D., Venosa,A., Kopp,M., Tomer,Y., Russo,S.J.,
            Headen,A.C., Basil,M.C., Stark,J.M., Mulugeta,S., Deterding,R.R.
            and Beers,M.F.
  TITLE     An SFTPC BRICHOS mutant links epithelial ER stress and spontaneous
            lung fibrosis
  JOURNAL   JCI Insight 4 (6), 126125 (2019)
   PUBMED   30721158
  REMARK    GeneRIF: An SFTPC BRICHOS mutant links epithelial ER stress and
            spontaneous lung fibrosis.
            Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK079437.1.
            
            [WARNING] On Feb 19, 2025 this sequence was replaced by
            NM_175682.4.
            
            On Apr 6, 2007 this sequence version replaced NM_175682.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK079437.1, BC096398.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-997               AK079437.1         2-998
FEATURES             Location/Qualifiers
     source          1..997
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.39 cM"
     gene            1..997
                     /gene="Bricd5"
                     /gene_synonym="9930021D14Rik"
                     /note="BRICHOS domain containing 5"
                     /db_xref="GeneID:319259"
                     /db_xref="MGI:MGI:2441766"
     exon            1..355
                     /gene="Bricd5"
                     /gene_synonym="9930021D14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             338..862
                     /gene="Bricd5"
                     /gene_synonym="9930021D14Rik"
                     /codon_start=1
                     /product="BRICHOS domain-containing protein 5"
                     /protein_id="NP_783613.1"
                     /db_xref="CCDS:CCDS28483.1"
                     /db_xref="GeneID:319259"
                     /db_xref="MGI:MGI:2441766"
                     /translation="MYSSPKPLLQMLRKTFPSSRVPWPNQTTLVDVAQNMATIVVTPF
                     QSNHSWAVLFDGQNGYICYRPAEHQACFLRLMEAQDWETLQLLLNTSRAQESHVPGRD
                     THYAQELLAVLGGHTVDPTQVGVSVQHLCADTPIYWTQWAEGPQRQRLIYLCIDICFP
                     SNICVSVCFYYLPD"
     exon            356..511
                     /gene="Bricd5"
                     /gene_synonym="9930021D14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            512..613
                     /gene="Bricd5"
                     /gene_synonym="9930021D14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            614..767
                     /gene="Bricd5"
                     /gene_synonym="9930021D14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            768..997
                     /gene="Bricd5"
                     /gene_synonym="9930021D14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      977..982
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bricd5"
                     /gene_synonym="9930021D14Rik"
                     /note="hexamer: AATAAA"
     polyA_site      997
                     /gene="Bricd5"
                     /gene_synonym="9930021D14Rik"
                     /note="major polyA site"
ORIGIN      
        1 gactcctcca aggggctgca gacaatcagt gcattgtcag caggggctgc agcatgaagc
       61 aagggcgcat ccacactgag agcctcaggt ccaagcctgc tgaggtaagt ctctaccacc
      121 cccaagacaa gaactcaggg atgccataga agaaaggaat gttaccacat accatcctca
      181 gccccttccc tgagtctcta agccagaagc cccacggcca gtactgtgcc ctcaggtgaa
      241 gaccaaaccc tgccataggg gctggagagc agcaggcctg ctgctgctgc tgacactgct
      301 cactgcgggg gccgtggctg gggggcttct tggcttcatg tacagctctc ccaagccgtt
      361 gctgcagatg ctccgaaaga ccttcccgag ctccagggta ccctggccca accaaactac
      421 tctagtggat gtggcccaga acatggcaac catcgtggtg actccgtttc agagcaacca
      481 cagctgggct gtgctgtttg acgggcagaa cggctacatc tgttaccgcc ctgcagagca
      541 ccaagcctgc ttcctccgtc tgatggaagc ccaagattgg gagaccctgc agctgctgct
      601 gaacacttcc agggcccaag agtcacatgt acctggccgg gatacccact atgcccagga
      661 gctgctggca gttttggggg gccatactgt ggaccctacc caagtgggag tttcagtgca
      721 acacctttgt gcagacactc ccatctactg gacccaatgg gcagaagggc cccagagaca
      781 gcggctgatc tacctctgca ttgacatctg cttcccgagc aacatctgtg tgtctgtctg
      841 cttttattac ctcccagact aagaccccct acccaagccc tcctggcctt tggttccata
      901 ggccagtcct gtccccacag gtcagtaagc tggccaggtc accagtacct atggaaggca
      961 gctgacagta gggattaata aacccagatt gcctggc
//
