LOCUS       NM_001033274            5137 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus bromodomain containing 1 (Brd1), mRNA.
ACCESSION   NM_001033274 XM_128275 XM_911868 XM_922179 XM_922196 XM_922199
            XM_922207
VERSION     NM_001033274.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5137)
  AUTHORS   Paternoster,V., Edhager,A.V., Qvist,P., Donskov,J.G., Shliaha,P.,
            Jensen,O.N., Mors,O., Nielsen,A.L., Borglum,A.D., Palmfeldt,J. and
            Christensen,J.H.
  TITLE     Inactivation of the Schizophrenia-associated BRD1 gene in Brain
            Causes Failure-to-thrive, Seizure Susceptibility and Abnormal
            Histone H3 Acetylation and N-tail Clipping
  JOURNAL   Mol Neurobiol 58 (9), 4495-4505 (2021)
   PUBMED   34056693
  REMARK    GeneRIF: Inactivation of the Schizophrenia-associated BRD1 gene in
            Brain Causes Failure-to-thrive, Seizure Susceptibility and Abnormal
            Histone H3 Acetylation and N-tail Clipping.
REFERENCE   2  (bases 1 to 5137)
  AUTHORS   Rajkumar,A.P., Qvist,P., Donskov,J.G., Lazarus,R., Pallesen,J.,
            Nava,N., Winther,G., Liebenberg,N., Cour,S.H., Paternoster,V.,
            Fryland,T., Palmfeldt,J., Fejgin,K., Mork,A., Nyegaard,M.,
            Pakkenberg,B., Didriksen,M., Nyengaard,J.R., Wegener,G., Mors,O.,
            Christensen,J.H. and Borglum,A.D.
  TITLE     Reduced Brd1 expression leads to reversible depression-like
            behaviors and gene-expression changes in female mice
  JOURNAL   Transl Psychiatry 10 (1), 239 (2020)
   PUBMED   32681022
  REMARK    GeneRIF: Reduced Brd1 expression leads to reversible
            depression-like behaviors and gene-expression changes in female
            mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5137)
  AUTHORS   Paternoster,V., Svanborg,M., Edhager,A.V., Rajkumar,A.P.,
            Eickhardt,E.A., Pallesen,J., Grove,J., Qvist,P., Fryland,T.,
            Wegener,G., Nyengaard,J.R., Mors,O., Palmfeldt,J., Borglum,A.D. and
            Christensen,J.H.
  TITLE     Brain proteome changes in female Brd1+/- mice unmask dendritic
            spine pathology and show enrichment for schizophrenia risk
  JOURNAL   Neurobiol Dis 124, 479-488 (2019)
   PUBMED   30590179
REFERENCE   4  (bases 1 to 5137)
  AUTHORS   Qvist,P., Eskildsen,S.F., Hansen,B., Baragji,M., Ringgaard,S.,
            Roovers,J., Paternoster,V., Molgaard,S., Corydon,T.J.,
            Stodkilde-Jorgensen,H., Glerup,S., Mors,O., Wegener,G.,
            Nyengaard,J.R., Borglum,A.D. and Christensen,J.H.
  TITLE     Brain volumetric alterations accompanied with loss of striatal
            medium-sized spiny neurons and cortical parvalbumin expressing
            interneurons in Brd1+/- mice
  JOURNAL   Sci Rep 8 (1), 16486 (2018)
   PUBMED   30405140
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5137)
  AUTHORS   Qvist,P., Rajkumar,A.P., Redrobe,J.P., Nyegaard,M.,
            Christensen,J.H., Mors,O., Wegener,G., Didriksen,M. and
            Borglum,A.D.
  TITLE     Mice heterozygous for an inactivated allele of the schizophrenia
            associated Brd1 gene display selective cognitive deficits with
            translational relevance to schizophrenia
  JOURNAL   Neurobiol Learn Mem 141, 44-52 (2017)
   PUBMED   28341151
  REMARK    GeneRIF: Brd1(+/-) mice exhibit relational encoding deficits,
            compromised working and long term memory, as well as impaired
            executive cognitive functioning with cognitive behaviors relying on
            medial prefrontal cortex being particularly affected. Akin to
            patients with schizophrenia, the cognitive deficits displayed by
            Brd1(+/)(-) mice are not global, but selective.
REFERENCE   6  (bases 1 to 5137)
  AUTHORS   Mishima,Y., Miyagi,S., Saraya,A., Negishi,M., Endoh,M., Endo,T.A.,
            Toyoda,T., Shinga,J., Katsumoto,T., Chiba,T., Yamaguchi,N.,
            Kitabayashi,I., Koseki,H. and Iwama,A.
  TITLE     The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation
            of H3K14 and required for fetal liver erythropoiesis
  JOURNAL   Blood 118 (9), 2443-2453 (2011)
   PUBMED   21753189
  REMARK    GeneRIF: The Hbo1-Brd1 complex is the major H3K14 HAT required for
            transcriptional activation of erythroid developmental regulator
            genes.
REFERENCE   7  (bases 1 to 5137)
  AUTHORS   Doyon,Y., Cayrou,C., Ullah,M., Landry,A.J., Cote,V., Selleck,W.,
            Lane,W.S., Tan,S., Yang,X.J. and Cote,J.
  TITLE     ING tumor suppressor proteins are critical regulators of chromatin
            acetylation required for genome expression and perpetuation
  JOURNAL   Mol Cell 21 (1), 51-64 (2006)
   PUBMED   16387653
REFERENCE   8  (bases 1 to 5137)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   9  (bases 1 to 5137)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 5137)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB610711.1, BC152356.1, AK149714.1, AK220233.1 and BC037388.1.
            
            On Jan 15, 2008 this sequence version replaced NM_001033274.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14995045.1787141.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-275               BB610711.1         13-287
            276-534             BC152356.1         3-261
            535-1079            AK149714.1         547-1091
            1080-4110           AK220233.1         1-3031
            4111-5137           BC037388.1         1438-2464
FEATURES             Location/Qualifiers
     source          1..5137
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 44.17 cM"
     gene            1..5137
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /note="bromodomain containing 1"
                     /db_xref="GeneID:223770"
                     /db_xref="MGI:MGI:1924161"
     exon            1..291
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     exon            292..1672
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     CDS             306..3875
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /note="bromodomain and PHD finger-containing protein 2"
                     /codon_start=1
                     /product="bromodomain-containing protein 1"
                     /protein_id="NP_001028446.2"
                     /db_xref="CCDS:CCDS27730.2"
                     /db_xref="GeneID:223770"
                     /db_xref="MGI:MGI:1924161"
                     /translation="MRRKGRCHRGSAARHPSSPCSIKHSPTRETLTYAQAQRMVEIEI
                     EGRLHRISIFDPLEIILEDDLTAQEMSECNSNKENSERPPVCLRTKRHKNNRVKKKNE
                     VLPSTHGTPASASALPEPKVRIVEYSPPSAPRRPPVYYKFIEKSAEELDNEVEYDMDE
                     EDYAWLEIINEKRKGDCVSAVSQNMFEFLMDRFEKESYCENQKQGEQQSLIDEDAVCC
                     ICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPN
                     KGGAFKKTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKG
                     VGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTGGSATFSVRKTAYCDVHTPPG
                     CTRRPLNIYGDVEMKNGVCRKESSVKTVRSTSKVRKKAKKAKKTLAEPCAVLPTVCAP
                     YIPPQRLNRIANQVAIQRKKQFVERAHSYWLLKRLSRNGAPLLRRLQSSLQSQRNTQQ
                     RENDEEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKREQVKVEQMAMELRLTP
                     LTVLLRSVLEQLQEKDPAKIFAQPVSLKEVPDYLDHIKHPMDFATMRKRLEAQGYKNL
                     HAFEEDFNLIVDNCMKYNAKDTVFYRAAVRLRDQGGVVLRQARREVESIGLEEASGMH
                     LPERPIAAPRRPFSWEEVDRLLDPANRAHMSLEEQLRELLDKLDLTCSMKSSGSRSKR
                     AKLLKKEIALLRNKLSQQHSQAPPTGAGTGGFEDEAAPLAPDTAEEGANSPPKLEPSD
                     ALPLPSNSETNSEPPTLNPVELHPEQSKLFKRVTFDNESHSTCTQSALVSGHPPEPTL
                     ASSGDVPAAAASAVAEPSSDVNRRTSVLFCKSKSVSPPKSAKNTETQPTSPQLGTKTF
                     LSVVLPRLETLLQPRKRSRSTCGDSEVEEESPGKRLDTGLTNGFGGARSEQEPGGGPG
                     RKAAPRRRCASESSICSSNSPLCDSSFSTPKCGRGKPALVRRHTLEDRSELISCIENG
                     NYAKAARIAAEVGQSNMWISTDAAASVLEPLKVVWAKCSGYPSYPALIIDPKMPRVPG
                     HHNGVTIPAPPLDVLKIGEHMQTKSEEKLFLVLFFDNKRSWQWLPKSKMVPLGVDETI
                     DKLKMMEGRNSSIRKAVRIAFDRAMNHLSRVHGEPASDLSDID"
     exon            1673..1829
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     exon            1830..1961
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     exon            1962..2090
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     exon            2091..2403
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     exon            2404..2664
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     exon            2665..3162
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     exon            3163..3298
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     exon            3299..3426
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     exon            3427..3536
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     exon            3537..3691
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     exon            3692..5137
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4853..4858
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
                     /note="hexamer: AATAAA"
     polyA_site      4876
                     /gene="Brd1"
                     /gene_synonym="1110059H06Rik; mKIAA4191"
ORIGIN      
        1 gctggggagc gagcagcgcc tcggcaggcg tccgagcagc tccgcgtccg cgtcctccgc
       61 ccggccgggc cccgagccgg cctcagccgg ccgtgccggc gccgccgacc ccgcccgagc
      121 cgcggcgccc tgcgggcccg gagccgctgg ccgagcgcgc cccggagccc ggcggggcac
      181 ggctgcgcgg ccgttggcgg aggagccgcg gcgccattag cgccgcctcg gccgcgccgg
      241 cctccgcgcc cgcccgcccg ccgggctccc gcggccgcgg cgcccccgaa ggtaatcatt
      301 gccaaatgag gaggaaagga cgatgccatc gaggttctgc agcgaggcat ccttcttccc
      361 cgtgcagtat taaacactcc cccactcgag aaacactgac ctacgcacaa gctcaaagga
      421 tggtggagat agaaatcgaa gggcgcttgc atcggatcag tatttttgat cccttggaga
      481 tcatactaga agatgacctc actgctcagg aaatgagtga atgtaacagt aataaggaga
      541 acagcgagag gccgcctgtt tgcttaagaa ctaagcgtca caaaaacaac agagtcaaaa
      601 agaaaaatga agtcctgccc agcacccacg gcacaccggc gtcagccagt gcccttcccg
      661 agcccaaggt gcggattgtg gagtacagtc ctccctctgc acccaggagg ccccctgtgt
      721 actacaagtt catcgagaag tcagccgagg agctggacaa cgaggtagag tacgacatgg
      781 atgaggaaga ctacgcctgg ctagagatca tcaatgagaa gcggaagggt gactgcgtct
      841 ctgccgtgtc acagaatatg tttgagttcc tgatggaccg cttcgagaag gagtcttact
      901 gtgagaacca gaagcagggt gagcagcagt ccttgataga tgaggacgct gtttgctgca
      961 tctgcatgga cggggagtgc cagaacagca acgttatact cttctgtgac atgtgcaacc
     1021 tggctgtgca ccaggagtgc tatggggtac cctacatccc cgagggccag tggctttgcc
     1081 gccactgcct gcagtctcgg gcccgccctg cggattgcgt gctgtgcccg aataagggcg
     1141 gtgccttcaa aaagacagac gatgaccgct ggggccacgt ggtatgtgcc ctgtggatcc
     1201 cagaggttgg ctttgccaac acggtattca ttgagcccat tgacggtgtg aggaacatcc
     1261 ctcctgcccg gtggaaactg acatgctacc tctgtaagca gaaaggcgtg ggtgcctgca
     1321 ttcagtgcca caaagcaaat tgctacacag cattccatgt gacatgtgcc cagaaggctg
     1381 gcctatacat gaagatggag cctgtgaagg agctgactgg aggcagcgcc acgttctctg
     1441 tcagaaagac tgcttactgt gatgtccaca cgcctccagg ctgtacccgg aggccgttga
     1501 acatttatgg agatgttgaa atgaaaaatg gtgtgtgtcg aaaagaaagc tcagtcaaaa
     1561 cggtcaggtc tacgtccaag gtcaggaaaa aagcaaaaaa ggctaagaaa acactggctg
     1621 agccctgtgc ggtcctgccg accgtgtgcg ctccgtatat cccccctcag agattaaata
     1681 ggattgcgaa tcaggtggcc attcagcgga agaagcagtt tgtggagcga gcccacagct
     1741 actggttgct caaaaggctg tctaggaatg gtgctcccct gttgcggcgg ctccagtcca
     1801 gcctgcagtc ccagagaaac acgcagcaga gagaaaatga tgaagagatg aaagctgcca
     1861 aagagaagct aaagtactgg cagcggctgc gacatgacct agagcgtgca cgcctgctaa
     1921 ttgagctgct gcgcaagcgg gagaaactca agagagagca ggtgaaggtg gagcagatgg
     1981 ctatggagct ccggctgacg ccgctaactg tgctgctacg ctcagtcctg gagcagctac
     2041 aggagaagga ccctgcaaag atctttgccc agcccgtgag tctcaaggag gtaccagatt
     2101 atttggatca cattaaacac cccatggact ttgctacaat gaggaaacgg ctagaagctc
     2161 aagggtataa aaacctccat gcctttgagg aggattttaa tctcattgta gataactgca
     2221 tgaagtacaa tgccaaggac accgtgtttt atagagctgc agtgaggctg cgcgaccagg
     2281 gaggggttgt cctgaggcag gcccggcgag aggtggagag cattggcctg gaagaggcct
     2341 cgggaatgca cctgcctgag cgacccatcg cagcccctcg gcggcccttc tcctgggaag
     2401 aggtggacag gttgctggac ccagccaaca gggcccacat gagcttggag gagcagctga
     2461 gagaacttct ggacaagttg gacctgacct gctccatgaa gtccagcggc tcacggagta
     2521 aacgggcaaa gctgcttaaa aaagagattg ctcttctccg aaacaagctg agccagcagc
     2581 acagccaggc tccgcccaca ggggcaggca cgggaggctt tgaagatgag gctgctccac
     2641 tggccccgga cacagcggag gaaggagcta actctccccc taaacttgaa ccatcagatg
     2701 cattacctct tccttcaaac tcggagacta actcagaacc accaaccctc aacccagtag
     2761 aactccaccc cgagcagagt aaactattca aaagagtcac atttgataat gaatcacata
     2821 gcacttgcac tcagagcgca ctggtaagcg gacaccctcc agagcccacc ctcgccagta
     2881 gtggcgatgt gccggcggcg gcggcctccg cagtggcgga gccatcaagc gatgtaaaca
     2941 gacgcacttc tgttctcttc tgcaaatcga aaagtgtaag ccccccaaag tctgccaaga
     3001 acactgaaac ccagccaact tctcctcagc tagggaccaa aacctttttg tctgtagtcc
     3061 ttccgaggtt ggagactcta ctgcagccaa ggaaaaggtc gaggagcaca tgtggagact
     3121 ccgaagtgga ggaggagtcc ccgggaaagc gcctggacac aggtctcacc aatggctttg
     3181 ggggtgctag aagcgaacag gagccaggag ggggcccagg gaggaaagct gcgccccggc
     3241 ggcgctgtgc atctgaatcc agtatttgtt ccagcaacag cccactctgc gactcaagct
     3301 ttagcacacc caagtgtggg cgagggaaac ctgcccttgt gcgaaggcac acgctagaag
     3361 accgaagcga gctgatatct tgtattgaaa atggaaacta cgctaaggcg gccaggattg
     3421 cagctgaggt gggccagagc aacatgtgga tttccactga cgctgctgcc tccgtcctgg
     3481 agcccctgaa ggtggtatgg gccaagtgca gcggctaccc ctcctaccca gcactgatta
     3541 ttgaccccaa gatgccacga gtgcctggcc accacaatgg cgtcaccatc cctgcgccgc
     3601 cgctggatgt gctgaagatc ggtgaacaca tgcagaccaa gtccgaggag aagctcttcc
     3661 ttgttctgtt tttcgacaat aagaggagct ggcagtggct tcccaagtcc aagatggtcc
     3721 ctcttggtgt cgacgagacc atcgacaagt tgaaaatgat ggaagggagg aactctagca
     3781 tccggaaggc tgtgcggatt gcatttgatc gagccatgaa tcatctgagc cgggtccatg
     3841 gggagccagc cagtgacctc agtgacattg actgaggtgg tttccagcaa aggcggtggc
     3901 caaagcctca gccagccggg agctctgtcc atagtgttga taagctgtac atgtttgtat
     3961 attgttcaga acttaactta ttctggtttt ctaggcgtag ttctttaatt ctttttcccc
     4021 tggggagggg aggtttcact tccaagtttt ctatgaaacc atctggtctt ggctttgcaa
     4081 gtgaggaggg tctgttgcga gcagtgtggt gttggggtcc cactgcaggt gccgagggcc
     4141 gaggcctcac ttattctaat ctgtagggtt tttttttttt tttaaagact tttgaatgtt
     4201 taataatttt gtagatcatg ctctttacac agagtaccgc ttatttaata agacgggatg
     4261 taaatttaca atgacaaatg tgtattttaa gaaagaaaat gacattattt tgaatggtac
     4321 tttgtgcaaa gagggaataa atttatgctg tgtgcatcac ttgcaaatca ccaaaaaatg
     4381 tcccgccagc tgctgccgga cagggcccgt tctcctcgtt gatctgactg ccctgagtct
     4441 cctgctctgc cctggctcct gcaggcgtgc ctcccagcgg gttatttatt gtagaaagtg
     4501 tactcatttg ctttataatg aaaaataaat ttgcaaaggt atattgatat gcatttttat
     4561 acaggcacat aaaaattcaa cttggtgtgg gagcagaatg tgttgcgagg ttatatacac
     4621 gactggcctg tgtgtacttt gattttgtaa cttgtaatct tttgtttaca atgaggagct
     4681 ttctgtaact tgttttcatt tagaacactt tggtagcaat agactttgga tacattttgt
     4741 atggtacatg tgatgtatat agaattagtc ctttattttt atttctaaga ggtaaagcat
     4801 tatgttaggg gaaaggcagg gtgggtttcc aaatttgcat ttttatatta aaaataaagt
     4861 gaagatttgg acagtgtggc cctctcattc ctgcatcact aggaggctgg gtgagctgta
     4921 gcctgaggga cgtgagggac tcggagcacc gggcctggag tgggtggtgt gacacacttg
     4981 atctaacagc tgactcggga tggcattatt tattattttg cctaatcata tttttatttt
     5041 aaagctaaat agttactaaa aattttaaat gttcttttaa atctacatgt ttgtaatatc
     5101 tccatagaaa cttgaaaata aaaagtcttc ctttggt
//
