LOCUS       NM_177772               2328 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus BPI fold containing family C (Bpifc), mRNA.
ACCESSION   NM_177772
VERSION     NM_177772.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2328)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2328)
  AUTHORS   Bingle,C.D., Seal,R.L. and Craven,C.J.
  TITLE     Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a
            subfamily of the BPI fold-containing superfamily
  JOURNAL   Biochem Soc Trans 39 (4), 977-983 (2011)
   PUBMED   21787333
REFERENCE   3  (bases 1 to 2328)
  AUTHORS   Bingle,C.D., LeClair,E.E., Havard,S., Bingle,L., Gillingham,P. and
            Craven,C.J.
  TITLE     Phylogenetic and evolutionary analysis of the PLUNC gene family
  JOURNAL   Protein Sci 13 (2), 422-430 (2004)
   PUBMED   14739326
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY142313.1, BC112376.1, AK028764.1 and BB527461.1.
            
            On Nov 28, 2007 this sequence version replaced NM_177772.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK132518.1, BC112376.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-314               BY142313.1         1-314
            315-1665            BC112376.1         303-1653
            1666-2316           AK028764.1         1663-2313
            2317-2328           BB527461.1         177-188
FEATURES             Location/Qualifiers
     source          1..2328
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 41.83 cM"
     gene            1..2328
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /note="BPI fold containing family C"
                     /db_xref="GeneID:270757"
                     /db_xref="MGI:MGI:3026884"
     exon            1..76
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..1600
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /note="bactericidal/permeability-increasing protein-like
                     2; BPI fold-containing family C protein"
                     /codon_start=1
                     /product="BPI fold-containing family C protein precursor"
                     /protein_id="NP_808440.2"
                     /db_xref="CCDS:CCDS48658.1"
                     /db_xref="GeneID:270757"
                     /db_xref="MGI:MGI:3026884"
                     /translation="MRTKQVPVLWACFLLWSLYIASSQTVYPGITARITQRALDYGLQ
                     VGMKVLEQLAKEIVIPDLNGSESLKFLKIDYVKYNFSNIKINAFSFPNTSLAFVPGVG
                     IRALSNHGTANISTNWSVKAPLFRDSGAANLFLSGIYFTGIVAFTRNDFGYPALELQD
                     CHVQVSHARVSFFGSLSALYNSFAEPMEKPILKNLNEMLCPIAISQVEQFNVNISALE
                     VLTKIDNYTVLDCSLISPPEITENHLDFNLKGAFYPLESLVDPPFTPAPFHLPESRDS
                     MLYIGISEYFFKSASFAHYVSGALGTTLSTREISNYFSQNVQGFGSVLSKIAEIYVLS
                     QPFILQMMATGPPMVNLQRNNFSLEFPAAVIMLTQLDNSTIQPIVSMDFVASTSVGLA
                     ILGQKLICSLSLNRFRLSLPENSQRDAKVVRFENILSSILHFGVLPLANTKLQQGFPL
                     PNPYNISFINSDIEVLEGYLLVSSDLAYDTSSKPQPNLNSWGDLNLVHRPWREQPTH"
     exon            77..200
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            201..321
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            322..450
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            451..606
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            607..670
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            671..731
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            732..823
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            824..1000
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1054
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1225
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1293
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1336
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1400
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1477
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     exon            1478..2328
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2306..2311
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /note="hexamer: AATAAA"
     polyA_site      2327
                     /gene="Bpifc"
                     /gene_synonym="4732454E24; Bpil2"
                     /note="major polyA site"
ORIGIN      
        1 agcagagaac actcctgctt caaaggtgaa gggaattgaa ggtactctcc agctttggac
       61 tcatcctggg cttgagatgc ggacaaagca ggtcccagtc ctctgggcat gctttctcct
      121 atggagtctc tacattgcct cctcccagac tgtctaccct ggaatcacgg cgaggatcac
      181 ccagcgtgca ctagactatg gtcttcaagt tgggatgaag gtactggagc aattggcaaa
      241 ggaaatcgtc atcccagatt tgaacggttc tgagtctctt aaatttctga agattgacta
      301 tgtaaagtac aacttctcaa acataaaaat caatgccttc tcattcccaa atacctcact
      361 ggccttcgta cctggggtag gcatcagagc actgagcaac cacggcactg ccaacatcag
      421 caccaactgg agcgtcaagg ctccactttt ccgagactcg ggagctgcca atctgttcct
      481 ctctggaatc tatttcactg gcatcgttgc ctttacccgt aatgactttg gttacccagc
      541 tctggaactc caagactgcc atgttcaagt gagccatgcc cgagtctcat ttttcggaag
      601 tctcagtgcc ctgtataact cctttgctga gcccatggag aaacccattc taaagaattt
      661 aaatgaaatg ctttgtccca ttgccatcag ccaagtggaa cagttcaatg tcaacatcag
      721 cgcactggag gttttaacca agattgacaa ctacacagtg ctggattgtt ccctgatcag
      781 tcctccagaa atcaccgaga accaccttga ctttaatttg aagggtgcgt tctaccctct
      841 ggaaagcctc gtggaccctc ccttcacacc agctcccttc catctcccag agagcagaga
      901 ttccatgctc tacattggca tctctgagta cttctttaaa tctgcgtcat ttgctcacta
      961 tgtatctggg gctcttggta ccacgctgtc cactagggag atttccaact atttcagtca
     1021 aaatgttcaa ggatttggca gcgtactctc caagattgca gagatctatg tcttgtccca
     1081 gccgttcata ctgcagatga tggccacagg gcctcctatg gtcaacttac aacgaaacaa
     1141 tttcagcctg gagttccctg ctgctgtcat catgctcact caactggata actctaccat
     1201 ccagcccatc gtctccatgg acttcgttgc tagtaccagt gttggcctgg ctattttggg
     1261 acaaaaactg atctgctcct tatctttgaa cagattccgc ctgtctttgc cagagaacag
     1321 ccaacgagat gctaaggttg tgagatttga gaatatcctg tcttccattc ttcacttcgg
     1381 cgtcctccca ctggccaaca caaaactgca gcaaggattt cctcttccca acccctacaa
     1441 tatctcattc atcaattcgg atattgaagt tcttgagggt taccttctgg tttctagtga
     1501 cctggcatat gacacatcct caaagccaca gccaaatctg aacagctggg gggatctgaa
     1561 cctagtacat agaccatgga gagaacagcc aacccattga tggcccgctc acaatacacc
     1621 ccaggaagta aacagccttc agtcccccag aaaccagaaa cctggaagat gaagaccgtg
     1681 catcctggat attaaagccc ttgtggaaaa ggtctccttc tggagccctg agagacctag
     1741 agtaaggtcg acagttaaaa tgatgaacag gaacaaggta gtgggagtgg ggtctgtgta
     1801 tgtgagcatg tgtaagcaca ttgtgtgcct gtgtttagcc tttgtgggaa agagtaaggc
     1861 atgtggatcc gaccaggtgg taaggttgta aggaacttgt ctgtatttgc attggtaggt
     1921 gtgtgtgtgt gtgtgtatgt gtgtctgtgt gtgcctctgt gtgtggtgtg tatctgtgtg
     1981 tgtgtgtgtc tgtgtctgtg tgtgtgtctg tgtgtctgtg tgtgtctctg tgtctgtgtt
     2041 tgtgtctgtg tctgtgtgtg tgcctctgtg tctgtgtgcc tctgtgtgtg tatgtatgtg
     2101 tgtgtgtgtg tgtgtgcctc tgtgtgtgtg tctgtgtgta tctgtgtgtg tgtgtgtgtg
     2161 taagactatg tctgctcttt agagactttc tacttttatt ggactttatg ttttatgttt
     2221 actattactg tcctgtgctt aattaaaatt gttttctaac gatgtcagaa tctatgtgtg
     2281 aaagctcctg tcctgaattt attttaataa aatatgacag aaaaatgg
//
